Prostaglandin E2 activates phospholipase C and elevates intracellular calcium in cultured myometrial cells: Involvement of EP1 and EP3 receptor subtypes

Endocrinology

Volumn 137, Issue 6, 1996, Pages 2572-2579

  Asbóth, Gergely ^a   Phaneuf, Sylvain ^a   Europe Finner, G Nicholas ^a   Tóth, Miklós ^b   Bernal, Andrés López ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHOLIPASE C; PROSTAGLANDIN E2; RECEPTOR SUBTYPE; BORDETELLA VIRULENCE FACTOR; CALCIUM; INOSITOL PHOSPHATE; OXYTOCIN; PERTUSSIS TOXIN; PROSTAGLANDIN E; PROSTAGLANDIN E RECEPTOR; PROSTANOID RECEPTOR EP1;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CHILDBIRTH; ENZYME ACTIVATION; FEMALE; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; HUMAN TISSUE; MYOMETRIUM; PRIORITY JOURNAL; RECEPTOR AFFINITY; SECOND MESSENGER; UTERUS CONTRACTILITY; CELL CULTURE; DRUG EFFECT; METABOLISM; PHYSIOLOGY;

CALCIUM; CELLS, CULTURED; DINOPROSTONE; ENZYME ACTIVATION; FEMALE; HUMANS; INOSITOL PHOSPHATES; MYOMETRIUM; OXYTOCIN; PERTUSSIS TOXIN; PHOSPHOLIPASE C; PROSTAGLANDINS E, SYNTHETIC; RECEPTORS, PROSTAGLANDIN E; VIRULENCE FACTORS, BORDETELLA;

EID: 85047676329     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.6.8641211     Document Type: Article

References (51)

1. Keirse MJNC 1979 Endogenous prostaglandins in human parturition. In: Keirse MJNC, Anderson ABM, Bennebroek Gravenhorst J (eds) Human Parturition. Uterine contractility. University Press, Leiden, pp 101-142
2. MacKenzie IZ, Castle BM, Mountford L, Ferguson L, Brennecke S, Embrey MP 1987 Prostaglandin release from preparations used vaginally for the induction of labour. Prostaglandins 34:939-946
3. Keirse MJNC 1992 Inhibitors of prostaglandin synthesis for treatment of preterm labour. In: Drife JO, Calder AA (eds) Prostaglandins and the Uterus. Springer-Verlag, London, pp 277-293
4. Wikland M, Lindblom B, Wilhelmsson L, Wiqvist N 1982 Oxytocin, prostaglandins, and contractility of the human uterus at term pregnancy. Acta Obstet Gynecol Scand 61:467-472
5. Senior J, Marshall K, Sangha R, Baxter GS, Clayton JK 1991 In vitro characterization of prostanoid EP receptors in the non-pregnant human myometrium. Br J Pharmacol 102:747-753
6. Senior J, Marshall K, Sangha R, Clayton JK 1993 In vitro characterization of prostanoid receptors on human myometrium at term pregnancy. Br J Pharmacol 108:501-506
7. Mackenzie LW, Word RA, Casey ML, Stull JT 1990 Myosin light chain phosphorylation in human myometrial smooth muscle cells. Am J Physiol 258:C92-C98
8. Wray S 1993 Uterine contraction and physiological mechanism for modulation. Am J Physiol 264:C1-C18
9. Diamond J 1990 Beta-adrenoceptors, cyclic AMP, and cyclic GMP in control of uterine motility. In: Carsten ME, Miller JD (eds) Uterine Function. Molecular and Cellular Aspects. Plenum Press, New York, pp 249-275
10. i, myosin light chain phosphorylation, and contraction in human myometrium. Am J Physiol 260:C861-C867
11. Smith WL 1989 The eicosanoids and their biochemical mechanisms of action. Biochem J 259:315-324
12. Coleman RA, Kennedy I, Humphrey PPA, Levy GP, Lumley P 1990 Prostanoids and their receptors. In: Hansch C, Sammes PG, Taylor JB (eds) Comprehensive Medicinal Chemistry. Pergamon Press, Oxford, pp 643-714
13. Bunce KT, Clayton NM, Coleman RA, Collington EW, Finch H, Humphray JM, Humphrey PPA, Reeves JJ, Scheldrick RLG, Stables R 1991 GR 63799X a novel prostanoid with selectivity for EP3 receptors. Adv Prostaglandin Thromboxane Leukotriene Res 21: 379-382
14. 2 sensitive (EP) receptors. Adv Prostaglandin Thromboxane Leukotriene Res 17:467-470
15. Reeves JJ, Bunce KT, Scheidrick RLG, Stables R 1988 Evidence for the PGE receptor subtype mediating inhibition of acid secretion in the rat. Br J Pharmacol 95:805P
16. Coleman RA, Kennedy I, Scheidrick RLG 1985 AH 6809, a prostanoid EP1 receptor blocking drug. Br J Pharmacol 85:273P
17. Dong YJ, Jones RL 1982 Effects of prostaglandins and thromboxane analogues on bullock and dog iris sphincter preparations. Br J Pharmacol 76:149-155
18. 2+ transients evoked by prostanoids in Swiss 3T3 cells suggest an FP receptor mediated response. Adv Prostaglandin Thromboxane Leukotriene Res 21A:367-370
19. Coleman RA, Smith WL, Narumiya S 1994 VIII. International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes. Pharmacol Rev 46:205-229
20. Goureau O, Tanfin Z, Marc S, Harbon S 1992 Diverse prostaglandin receptors activate distinct signal transduction pathways in rat myometrium. Am J Physiol 263:C257-C265
21. Kimura T, Tanizawa O, Mori K, Brownstein MJ, Okayama H 1992 Structure and expression of a human oxytocin receptor. Nature 356:526-529
22. Phaneuf S, Europe-Finner GN, Varney M, MacKenzie IZ, Watson SP, López Bernal A 1993 Oxytocin-stimulated phosphoinositide hydrolysis in human myometrial cells: involvement of pertussis toxin-sensitive and -insensitive G-proteins. J Endocrinol 136:497-509
23. Casey ML, MacDonald PC, Mitchell MD, Snyder JM 1984 Maintenance and characterisation of human myometrial smooth muscle cells in monolayer culture. In Vitro 20:396-403
24. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450
25. Bone EA, Fretten P, Palmer S, Kirk CS, Michell RM 1984 Rapid accumulation of inositol phosphates in isolated rat superior cervical sympathetic ganglia exposed to V1-vasopressin and muscarinic cholinergic stimuli. Biochem J 221:803-811
26. Phaneuf S, Berta P, Peuch LP, Haiech J, Cavadore JC 1988 Phorbol ester modulation of cyclic AMP accumulation in a primary culture of rat aortic smooth muscle cells. J Pharmacol Exp Ther 245:1042-1047
27. Laemmli UK 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
28. i signaling in pregnant human myometrium. Am J Physiol 264:E77-E87
29. 2α stimulates inositol phosphate production in human pregnant myometrium. Prostaglandins 45:269-283
30. 2 receptor transduce both intracellular calcium and cAMP signals. Biochemistry 33:14496-14502
31. Irie A, Segi E, Sugimoto Y, Ichikawa A, Negishi M 1994 Mouse prostaglandin E receptor EP3 subtype mediates calcium signals via Gi in cDNA transfected Chinese hamster ovary cells. Biochem Biophys Res Commun 204:303-309
32. Namba T, Sugimoto T, Negishi M, Irie A, Ushikubi F, Kakizuka A, Ito S, Ichikawa A, Narumiya S 1993 Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity. Nature 365:166-170
33. Adam M, Boie Y, Rushmore TH, Muller G, Bastien L, McKee KT, Metters KM, Abramowitz M 1994 Cloning and expression of three isoforms of the human EP3 prostanoid receptor. FEBS Lett 338:170-174
34. Regan JW, Bailey TJ, Donello JE, Pierce KL, Pepperl DJ, Zhang D, Kedzie KM, Fairbairn CE, Bogardus AM, Woodward DF, Gil DW 1994 Molecular cloning and expression of human EP3 receptors: evidence of three variants with differing carboxyl termini. Br J Pharmacol 112:377-385
35. Schmid A, Thierauch KH, Schleuning WD, Dinter H 1995 Splice variants of the human EP3 receptor for prostaglandin E2. Eur J Biochem 228:23-30
36. Simon MI, Strathmann MP, Gautam N 1991 Diversity of G proteins in signal transduction. Science 252:802-808
37. Negishi M, Sugimoto Y, Hayashi Y, Namba T, Honda A, Watabe A, Narumiya S, Ichikawa A 1993 Functional interaction of prostaglandin E receptor EP3 subtype with guanin nucleotide binding proteins showing low affinity ligand binding. Biochim Biophys Acta 1175:343-350
38. Schwaner I, Offermans S, Spicher K, Seifert R, Schultz G 1995 Differential activation of Gi and Gs proteins by E type and I type prostaglandins in membranes from the human erythroleukaemia cell line. Biochim Biophys Acta 1265:8-14
39. s in pregnancy. Endocrinology 132:2484-2490
40. Phaneuf S, Carrasco MP, Europe-Finner GN, Hamilton CH, López Bernai A, Multiple G proteins and phospholipase C isoforms in human myometrial cells. Implication for oxytocin action. J Clin Endocrinol Metab, in press
41. 2 alpha: comparison with oxytocin. J Clin Endocrinol Metab 71:1243-1250
42. q/11. Endocrinology 136:1509-1515
43. Funk CD, Furci L, FitzGerald GA, Grygorczyk R, Rochette Ch, Bayne MA, Abramowitz M, Adam M, Metters K 1993 Cloning and expression of a cDNA for the human prostaglandin E receptor EP1 subtype. J Biol Chem 268:26767-26772
44. Watabe A, Sugimoto Y, Honda A, Irie T, Namba T, Negishi M, Ito S, Narumiya S, Ichikawa A 1993 Cloning and expression of cDNA for a mouse EP1 subtype of prostaglandin E receptor. J Biol Chem 268:20175-20178
45. 2+ mobilization in human myometrial cells. J Clin Endocrinol Metab, in press
46. 2 in single cultured human myometrial cells. Exp Physiol 77:293-305
47. Galione A 1993 Cyclic ADP-ribose: a new way to control calcium. Science 259:325-326
48. Ghosh TK, Bian J, Gill DL 1990 Intracellular calcium release mediated by sphingosine derivatives generated in cells. Science 248: 1653-1656
49. Lee HCh, Aarhus R 1995 A derivative of NADP mobilizes calcium stores insensitive to inositol triphosphate and cyclic ADP ribose. J Biol Chem 270:2152-2157
50. Mironneau J 1990 Ion channels and excitation-contraction coupling in myometrium. In: Garfield RE (ed) Uterine Contractility, Serono Symposia, Norwell, pp 9-19
51. McDonald TF, Pelzer S, Trautwein W, Pelzer DJ 1994 Regulation and modulation of calcium channels in cardiac skeletal and smooth muscle cells Physiol Rev 74:365-507