GM1 and NGF modulate Ca2+ homeostasis and GAP43 mRNA expression in cultured dorsal root ganglion neurons with excitotoxicity induced by glutamate

Nutritional Neuroscience

Volumn 10, Issue 3-4, 2007, Pages 105-111

  Huang, Fei ^a,b   Liu, Zhen ^a   Liu, Huaxiang ^c   Wang, Lihong ^a   Wang, Huaijing ^a   Li, Zhenzhong ^a  

^a SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b BINZHOU MEDICAL UNIVERSITY   (China)

^c SHANDONG UNIVERSITY   (China)

Author keywords

Dorsal root ganglion; Glutamate; GM1; Neuroprotective effect; Neurotoxicity; NGF

Indexed keywords

CALCIUM; GANGLIOSIDE GM1; GLUTAMIC ACID; MESSENGER RNA; NERVE GROWTH FACTOR; NEUROMODULIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG POTENTIATION; EMBRYO; FLUORESCENCE ANALYSIS; GENE EXPRESSION; IN VITRO STUDY; NERVE CELL CULTURE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINAL GANGLION;

ANIMALS; CALCIUM; CELLS, CULTURED; GANGLIA, SPINAL; GANGLIOSIDES; GAP-43 PROTEIN; HOMEOSTASIS; NERVE GROWTH FACTORS; NEURONS; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

RATTUS;

EID: 34848851402     PISSN: 1028415X     EISSN: 14768305     Source Type: Journal    
DOI: 10.1080/10284150701406752     Document Type: Article

References (48)

1. Ahmed, I., Calle, Y., Iwashita, S. and Nur-E-Kamal, A. (2006) Role of Cdc42 in neurite outgrowth of PC12 cells and cerebellar granule neurons. Mol Cell Biochem, 281, pp. 17-25.
2. Anderson, KD, Merhege, MA, Morin, M., Bolognani, F. and Perrone-Bizzozero, NI (2003) Increased expression and localization of the RNA-binding protein HuD and GAP-43 mRNA to cytoplasmic granules in DRG neurons during nerve regeneration. Exp Neurol, 183, pp. 100-108.
3. Bachis, A., Rabin, SJ, Fiacco, M Del and Mocchetti, I. (2002) Gangliosides prevent excitotoxicity through activation of TrkB receptor. Neurotox Res, 4, pp. 225-234.
4. Bezprozvanny, I. and Hayden, MR (2004) Deranged neuronal calcium signaling and Huntington disease. Biochem Biophys Res Commun, 322, pp. 1310-1317.
5. Bolsover, SR (2005) Calcium signalling in growth cone migration. Cell Calcium, 37, pp. 395-402.
6. Brocard, JB, Tassetto, M. and Reynolds, IJ (2001) Quantitative evaluation of mitochondrial calcium content in rat cortical neurones following a glutamate stimulus. J Physiol, 531, pp. 793-805.
7. Cafferty, WB, Gardiner, NJ, Das, P., Qiu, J., McMahon, SB and Thompson, SW (2004) Conditioning injury-induced spinal axon regeneration fails in interleukin-6 knock-out mice. J Neurosci, 24, pp. 4432-4443.
8. Choi, JS, Kim, JA and Joo, CK (2003) Activation of MAPK and CREB by GM1 induces survival of RGCs in the retina with axotomized nerve. Invest Ophthalmol Vis Sci, 44, pp. 1747-1752.
9. Cunha, GM, Moraes, RA, Moraes, GA, Franca Jr., MC, Moraes, MO and Viana, GS (1999) Nerve growth factor, ganglioside and vitamin E reverse glutamate cytotoxicity in hippocampal cells. Eur J Pharmacol, 367, pp. 107-112.
10. Edling, Y., Ingelman-Sundberg, M. and Simi, A. (2007) Glutamate activates c-fos in glial cells via a novel mechanism involving the glutamate receptor subtype mGlu5 and the transcriptional repressor DREAM. Glia, 55, pp. 328-340.
11. Farooqui, T., Franklin, T., Pearl, DK and Yates, AJ (1997) Ganglioside GM1 enhances induction by nerve growth factor of a putative dimer of TrkA. J Neurochem, 68, pp. 2348-2355.
12. Fleming, J., Ginn, SL, Weinberger, RP, Trahair, TN, Smythe, JA and Alexander, IE (2001) Adeno-associated virus and lentivirus vectors mediate efficient and sustained transduction of cultured mouse and human dorsal root ganglia sensory neurons. Hum Gene Ther, 12, pp. 77-86.
13. Fong, TG, Vogelsberg, V., Neff, NH and Hadjiconstantinou, M. (1995) GM1 and NGF synergism on choline acetyltransferase and choline uptake in aged brain. Neurobiol Aging, 16, pp. 917-923.
14. Gericke, CA, Schulte-Herbruggen, O., Arendt, T. and Hellweg, R. (2006) Chronic alcohol intoxication in rats leads to a strong but transient increase in NGF levels in distinct brain regions. J Neural Transm, 113, pp. 813-820.
15. Goettl, VM, Neff, NH and Hadjiconstantinou, M. (2003) Sciatic nerve axotomy in aged rats: Response of motoneurons and the effect of GM1 ganglioside treatment. Brain Res, 968, pp. 44-53.
16. Hiroi, S., Taira, E., Ogawa, K. and Tsukamoto, Y. (2005) Neurite extension of DRG neurons by gicerin expression is enhanced by nerve growth factor. Int J Mol Med, 16, pp. 1009-1014.
17. Kakinoki, B., Sekimoto, S., Yuki, S., Ohgami, T., Sejima, M., Yamagami, K. and Saito, K. (2006) Orally active neurotrophin-enhancing agent protects against dysfunctions of the peripheral nerves in hyperglycemic animals. Diabetes, 55, pp. 616-621.
18. Kato, N., Nemoto, K., Arino, H. and Fujikawa, K. (2003) Influence of peripheral inflammation on growth-associated phosphoprotein (GAP-43) expression in dorsal root ganglia and on nerve recovery after crush injury. Neurosci Res, 45, pp. 297-303.
19. Kushnareva, YE, Wiley, SE, Ward, MW, Andreyev, AY and Murphy, AN (2005) Excitotoxic injury to mitochondria isolated from cultured neurons. J Biol Chem, 280, pp. 28894-28902.
20. Liu, JR, Ding, MP, Wei, EQ, Huang, JZ, Song, Y., Ding, Q. and Ge, QF (2004) Monosialoganglioside protected ischemic rat hippocampal slices through stabilizing expression of N-methyl-d-aspartate receptor subunit. Acta Pharmacol Sin, 25, pp. 727-732.
21. Zheng, YL, Luo, L., Wu, DM, Sun, DX and Feng, YJ (2006) Quercetin reverses d-galactose induced neurotoxicity in mouse brain. Behav Brain Res, 171, pp. 251-260.
22. Merighi, A., Carmignoto, G., Gobbo, S., Lossi, L., Salio, C., Vergnano, AM and Zonta, M. (2004) Neurotrophins in spinal cord nociceptive pathways. Prog Brain Res, 146, pp. 291-321.
23. Montell, C. (2005) The latest waves in calcium signaling. Cell, 122, pp. 157-163.
24. Ren, Q., Duchemin, AM, Neff, NH and Hadjiconstantinou, M. (2005) GM1 and ERK signaling in the aged brain. Brain Res, 1054, pp. 125-134.
25. Mutoh, T., Hamano, T., Yano, S., Koga, H., Yamamoto, H., Furukawa, K. and Ledeen, RW (2002) Stable transfection of GM1 synthase gene into GM1-deficient NG108-15 cells, CR-72 cells, rescues the responsiveness of Trk-neurotrophin receptor to its ligand, NGF. Neurochem Res, 27, pp. 801-806.
26. Nicholls, DG (2004) Mitochondrial dysfunction and glutamate excitotoxicity studied in primary neuronal cultures. Curr Mol Med, 4, pp. 149-177.
27. Nishio, M., Fukumoto, S., Furukawa, K., Ichimura, A., Miyazaki, H., Kusunoki, S., Urano, T. and Furukawa, K. (2004) Overexpressed GM1 suppresses nerve growth factor (NGF) signals by modulating the intracellular localization of NGF receptors and membrane fluidity in PC12 cells. J Biol Chem, 279, pp. 33368-33378.
28. Petruska, JC and Mendell, LM (2004) The many functions of nerve growth factor: Multiple actions on nociceptors. Neurosci Lett, 361, pp. 168-171.
29. Rabin, SJ, Bachis, A. and Mocchetti, I. (2002) Gangliosides activate Trk receptors by inducing the release of neurotrophins. J Biol Chem, 277, pp. 49466-49472.
30. Rameau, GA, Tukey, DS, Garcin-Hosfield, ED, Titcombe, RF, Misra, C., Khatri, L., Getzoff, ED and Ziff, EB (2007) Biphasic coupling of neuronal nitric oxide synthase phosphorylation to the NMDA receptor regulates AMPA receptor trafficking and neuronal cell death. J Neurosci, 27, pp. 3445-3455.
31. Rodriguez, JA, Piddini, E., Hasegawa, T., Miyagi, T. and Dotti, CG (2001) Plasma membrane ganglioside sialidase regulates axonal growth and regeneration in hippocampal neurons in culture. J Neurosci, 21, pp. 8387-8395.
32. Sanelli, T., Leystra-Lantz, C. and Strong, MJ (2007) Calcium mediated excitotoxicity in neurofilament aggregate-bearing neurons in vitro is NMDA receptor dependant. J Neurol Sci, 256, pp. 39-51.
33. Shimohama, S., Ogawa, N., Tamura, Y., Akaike, A., Tsukahara, T., Iwata, H. and Kimura, J. (1993) Protective effect of nerve growth factor against glutamate-induced neurotoxicity in cultured cortical neurons. Brain Res, 632, pp. 296-302.
34. Skoff, AM and Adler, JE (2006) Nerve growth factor regulates substance P in adult sensory neurons through both TrkA and p75 receptors. Exp Neurol, 197, pp. 430-436.
35. 2+ signaling and apoptosis of medium spiny neurons in Huntington's disease. Proc Natl Acad Sci USA, 102, pp. 2602-2607.
36. Tsai, SY, Yang, LY, Wu, CH, Chang, SF, Hsu, CY, Wei, CP, Leu, SJ, Liaw, J., Lee, YH and Tsai, MD (2007) Injury-induced Janus kinase/protein kinase C-dependent phosphorylation of growth-associated protein 43 and signal transducer and activator of transcription 3 for neurite growth in dorsal root ganglion. J Neurosci Res, 85, pp. 321-331.
37. Tymianski, M., Charlton, MP, Carlen, PL and Tator, CH (1993) Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons. J Neurosci, 13, pp. 2085-2104.
38. Villoslada, P. and Genain, CP (2004) Role of nerve growth factor and other trophic factors in brain inflammation. Prog Brain Res, 146, pp. 403-414.
39. Vorwerk, CK, Bonheur, J., Kreutz, MR, Dreyer, EB and Laev, H. (1999) GM1 ganglioside administration protects spinal neurons after glutamate excitotoxicity. Restor Neurol Neurosci, 14, pp. 47-51.
40. Wang, GJ and Thayer, SA (2002) NMDA-induced calcium loads recycle across the mitochondrial inner membrane of hippocampal neurons in culture. J Neurophysiol, 87, pp. 740-749.
41. Ward, MW, Kushnareva, Y., Greenwood, S. and Connolly, CN (2005) Cellular and subcellular calcium accumulation during glutamate-induced injury in cerebellar granule neurons. J Neurochem, 92, pp. 1081-1090.
42. Wilcox, CL, Smith, RL, Freed, CR and Johnson, EM (1990) Nerve growth factor-dependence of herpes simplex virus latency in peripheral sympathetic and sensory neurons in vitro. J Neurosci, 10, pp. 1268-1275.
43. Lu, ZH, Xie, X. and Ledeen, RW (2004) Susceptibility of cerebellar granule neurons from GM2/GD2 synthase-null mice to apoptosis induced by glutamate excitotoxicity and elevated KCl: Rescue by GM1 and LIGA20. Glycoconj J, 21, pp. 305-313.
44. Lu, ZH, Wang, J., Wang, Y., Xie, X., Meyenhofer, MF and Ledeen, RW (2005) Enhanced susceptibility to kainate-induced seizures, neuronal apoptosis, and death in mice lacking gangliotetraose gangliosides: Protection with LIGA 20, a membrane-permeant analog of GM1. J Neurosci, 25, pp. 11014-11022.
45. Xie, X., Lu, ZH and Ledeen, RW (2002) Potentiation of a sodium-calcium exchanger in the nuclear envelope by nuclear GM1 ganglioside. J Neurochem, 81, pp. 1185-1195.
46. Yamada, T., Terashima, T., Okubo, T., Juneja, LR and Yokogoshi, H. (2005) Effects of theanine, r-glutamylethylamide, on neurotransmitter release and its relationship with glutamic acid neurotransmission. Nutr Neurosci, 8, pp. 219-226.
47. Yamamoto, N., Fukata, Y., Fukata, M. and Yanagisawa, K. (2007) GM1-ganglioside-induced Abeta assembly on synaptic membranes of cultured neurons. Biochim Biophys Acta, 1768, pp. 1128-1137.
48. Zhou, Z., Chen, H., Zhang, K., Yang, H., Liu, J. and Huang, Q. (2003) Protective effect of nerve growth factor on neurons after traumatic brain injury. J Basic Clin Physiol Pharmacol, 14, pp. 217-224.