-
1
-
-
33646084606
-
Separation of μ-opioid receptor desensitization and internalization: Endogenous receptors in primary neuronal cultures
-
Arttamangkul S., Torrecilla M., Kobayashi K., Okano H. Williams J. T. (2006) Separation of μ-opioid receptor desensitization and internalization: endogenous receptors in primary neuronal cultures. J. Neurosci. 26, 4118 4125.
-
(2006)
J. Neurosci.
, vol.26
, pp. 4118-4125
-
-
Arttamangkul, S.1
Torrecilla, M.2
Kobayashi, K.3
Okano, H.4
Williams, J.T.5
-
2
-
-
33748590520
-
DEP-domain-mediated regulation of GPCR signaling responses
-
Ballon D. R., Flanary P. L., Gladue D. P., Konopka J. B., Dohlman H. G. Thorner J. (2006) DEP-domain-mediated regulation of GPCR signaling responses. Cell 126, 1079 1093.
-
(2006)
Cell
, vol.126
, pp. 1079-1093
-
-
Ballon, D.R.1
Flanary, P.L.2
Gladue, D.P.3
Konopka, J.B.4
Dohlman, H.G.5
Thorner, J.6
-
3
-
-
0031916822
-
Mammalian RGS proteins: Barbarians at the gates
-
Berman D. M. Gilman A. G. (1998) Mammalian RGS proteins: barbarians at the gates. J. Biol. Chem. 273, 1269 1272.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 1269-1272
-
-
Berman, D.M.1
Gilman, A.G.2
-
4
-
-
0033601341
-
Enhanced morphine analgesia in mice lacking β-arrestin 2
-
Bohn L. M., Lefkowitz R. J., Gainetdinov R. R., Peppel K., Caron M. G. Lin F. T. (1999) Enhanced morphine analgesia in mice lacking β-arrestin 2. Science 286, 2495 2498.
-
(1999)
Science
, vol.286
, pp. 2495-2498
-
-
Bohn, L.M.1
Lefkowitz, R.J.2
Gainetdinov, R.R.3
Peppel, K.4
Caron, M.G.5
Lin, F.T.6
-
5
-
-
0034619796
-
Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence
-
Bohn L. M., Gaietdinov R. R., Lin F. S., Lefkowitz R. R. Caron M. G. (2000) Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence. Nature 408, 720 723.
-
(2000)
Nature
, vol.408
, pp. 720-723
-
-
Bohn, L.M.1
Gaietdinov, R.R.2
Lin, F.S.3
Lefkowitz, R.R.4
Caron, M.G.5
-
6
-
-
0034598728
-
Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1
-
Chen C. K., Burns M. E., He W., Wensel T., Baylor D. A. Simon M. I. (2000) Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1. Nature 403, 557 560.
-
(2000)
Nature
, vol.403
, pp. 557-560
-
-
Chen, C.K.1
Burns, M.E.2
He, W.3
Wensel, T.4
Baylor, D.A.5
Simon, M.I.6
-
9
-
-
0031041306
-
RGS proteins and signaling by heterotrimeric G proteins
-
Dohlman H. G. Thorner J. (1997) RGS proteins and signaling by heterotrimeric G proteins. J. Biol. Chem. 272, 3871 3874.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3871-3874
-
-
Dohlman, H.G.1
Thorner, J.2
-
10
-
-
0141744853
-
Brain region-specific mechanisms for acute morphine-induced mitogen-activated protein kinase modulation and distinct patterns of activation during analgesic tolerance and locomotor sensitization
-
Eitan S., Bryant C. D., Saliminejad N., Yang Y. C., Vojdani E., Keith D. Jr., Polakiewicz R. Evans C. J. (2003) Brain region-specific mechanisms for acute morphine-induced mitogen-activated protein kinase modulation and distinct patterns of activation during analgesic tolerance and locomotor sensitization. J. Neurosci. 23, 8360 8369.
-
(2003)
J. Neurosci.
, vol.23
, pp. 8360-8369
-
-
Eitan, S.1
Bryant, C.D.2
Saliminejad, N.3
Yang, Y.C.4
Vojdani, E.5
Keith Jr., D.6
Polakiewicz, R.7
Evans, C.J.8
-
11
-
-
4644374022
-
Secrets of the opium poppy revealed
-
Evans C. J. (2004) Secrets of the opium poppy revealed. Neuropharmacology 47 (Suppl. 1 293 299.
-
(2004)
Neuropharmacology
, vol.47
, Issue.1
, pp. 293-299
-
-
Evans, C.J.1
-
12
-
-
19244367478
-
The R7 subfamily of RGS proteins assists tachyphylaxis and acute tolerance at mu-opioid receptors
-
Garzon J., López-Fando A. Sánchez-Blázquez P. (2003) The R7 subfamily of RGS proteins assists tachyphylaxis and acute tolerance at mu-opioid receptors. Neuropsychopharmacology 28, 1983 1990.
-
(2003)
Neuropsychopharmacology
, vol.28
, pp. 1983-1990
-
-
Garzon, J.1
López-Fando, A.2
Sánchez-Blázquez, P.3
-
13
-
-
0030764226
-
Regulators of G-protein signaling (RGS) proteins: Region-specific expression of nine subtypes in rat brain
-
Gold S. J., Ni Y. G., Dohlman H. G. Nestler E. J. (1997) Regulators of G-protein signaling (RGS) proteins: region-specific expression of nine subtypes in rat brain. J. Neurosci. 17, 8024 8037.
-
(1997)
J. Neurosci.
, vol.17
, pp. 8024-8037
-
-
Gold, S.J.1
Ni, Y.G.2
Dohlman, H.G.3
Nestler, E.J.4
-
14
-
-
0027457992
-
Pigment dispersion in frog melanophores can be induced by a phorbol ester or stimulation of a recombinant receptor that activates phospholipase C
-
Graminski G. F., Jayawickreme C. K., Potenza M. N. Lerner M. R. (1993) Pigment dispersion in frog melanophores can be induced by a phorbol ester or stimulation of a recombinant receptor that activates phospholipase C. J. Biol. Chem. 1268, 5957 5964.
-
(1993)
J. Biol. Chem.
, vol.1268
, pp. 5957-5964
-
-
Graminski, G.F.1
Jayawickreme, C.K.2
Potenza, M.N.3
Lerner, M.R.4
-
15
-
-
0038380503
-
Morphine acutely regulates opioid receptor trafficking selectively in dendrites of nucleus accumbens neurons
-
Haberstock-Debic H., Wein M., Barrot M., Colago E. E., Rahman Z., Neve R. L., Pickel V. M., Nestler E. J., von Zastrow M. Svingos A. L. (2003) Morphine acutely regulates opioid receptor trafficking selectively in dendrites of nucleus accumbens neurons. J. Neurosci. 23, 4324 4332.
-
(2003)
J. Neurosci.
, vol.23
, pp. 4324-4332
-
-
Haberstock-Debic, H.1
Wein, M.2
Barrot, M.3
Colago, E.E.4
Rahman, Z.5
Neve, R.L.6
Pickel, V.M.7
Nestler, E.J.8
Von Zastrow, M.9
Svingos, A.L.10
-
16
-
-
23944437411
-
Morphine promotes rapid. Arrestin-dependent endocytosis of mu-opioid receptors in striatal neurons
-
Haberstock-Debic H., Kim K., Joy Yu Y. von Zastrow M. (2005) Morphine promotes rapid. Arrestin-dependent endocytosis of mu-opioid receptors in striatal neurons. J. Neurosci. 25, 7847 7857.
-
(2005)
J. Neurosci.
, vol.25
, pp. 7847-7857
-
-
Haberstock-Debic, H.1
Kim, K.2
Joy Yu, Y.3
Von Zastrow, M.4
-
17
-
-
0034711252
-
Modules in the photoreceptor RGS9-1.G beta 5L GTPase-accelerating protein complex control effector coupling, GTPase acceleration, protein folding, and stability
-
He W., Lu L., Zhang X., El-Hodiri H. M., Chen C. K., Slep K. C., Simon M. I., Jamrich M. Wensel T. G. (2000) Modules in the photoreceptor RGS9-1.G beta 5L GTPase-accelerating protein complex control effector coupling, GTPase acceleration, protein folding, and stability. J. Biol. Chem. 275, 37093 37100.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 37093-37100
-
-
He, W.1
Lu, L.2
Zhang, X.3
El-Hodiri, H.M.4
Chen, C.K.5
Slep, K.C.6
Simon, M.I.7
Jamrich, M.8
Wensel, T.G.9
-
18
-
-
0036733358
-
Cellular regulation of RGS proteins: Modulators and integrators of G protein signaling
-
Hollinger S. Hepler J. R. (2002) Cellular regulation of RGS proteins: modulators and integrators of G protein signaling. Pharmacol. Rev. 54, 527 559.
-
(2002)
Pharmacol. Rev.
, vol.54
, pp. 527-559
-
-
Hollinger, S.1
Hepler, J.R.2
-
19
-
-
0036323891
-
Clinical pharmacology of opioids for pain
-
Inturrisi C. E. (2002) Clinical pharmacology of opioids for pain. Clin. J. Pain 18 (4 Suppl. S3 S13.
-
(2002)
Clin. J. Pain
, vol.18
, Issue.4
-
-
Inturrisi, C.E.1
-
20
-
-
11244344642
-
Receptor endocytosis counteracts the development of opioid tolerance
-
Koch T., Widera A., Bartzsch K., Schulz S., Brandenburg L. O., Wundrack N., Beyer A., Grecksch G. Holt V. (2005) Receptor endocytosis counteracts the development of opioid tolerance. Mol. Pharmacol. 67, 280 287.
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 280-287
-
-
Koch, T.1
Widera, A.2
Bartzsch, K.3
Schulz, S.4
Brandenburg, L.O.5
Wundrack, N.6
Beyer, A.7
Grecksch, G.8
Holt, V.9
-
21
-
-
20044362374
-
2 Dopamine receptors colocalize regulator of G-protein signaling 9-2 (RGS9-2) via the RGS9 DEP domain, and RGS9 knockout mice develop dyskinesias associated with dopamine pathways
-
2 Dopamine receptors colocalize regulator of G-protein signaling 9-2 (RGS9-2) via the RGS9 DEP domain, and RGS9 knockout mice develop dyskinesias associated with dopamine pathways. J. Neurosci. 25, 2157 2165.
-
(2005)
J. Neurosci.
, vol.25
, pp. 2157-2165
-
-
Kovoor, A.1
Sevffarth, P.2
Ebert, J.3
-
22
-
-
17644402459
-
Transduction of receptor signals by beta arrestins
-
Lefkowitz R. J. Shenoy S. K. (2005) Transduction of receptor signals by beta arrestins. Science 308, 512 517.
-
(2005)
Science
, vol.308
, pp. 512-517
-
-
Lefkowitz, R.J.1
Shenoy, S.K.2
-
23
-
-
0345687489
-
The DEP domain determines subcellular targeting of the GTPase activating protein RGS9 in vivo
-
Martemyanov K. A. et al. (2003) The DEP domain determines subcellular targeting of the GTPase activating protein RGS9 in vivo. J. Neurosci. 23, 10175 10181.
-
(2003)
J. Neurosci.
, vol.23
, pp. 10175-10181
-
-
Martemyanov, K.A.1
-
24
-
-
0029852678
-
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene
-
Matthes H. W. et al. (1996) Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene. Nature 383, 819 823.
-
(1996)
Nature
, vol.383
, pp. 819-823
-
-
Matthes, H.W.1
-
25
-
-
3342917288
-
In vivo regulation of extracellular signal-regulated protein kinase (ERK) and protein kinase B (Akt) phosphorylation by acute and chronic Morphine
-
Muller D. L. Unterwald E. M. (2004) In vivo regulation of extracellular signal-regulated protein kinase (ERK) and protein kinase B (Akt) phosphorylation by acute and chronic Morphine. J. Pharmacol. Exp. Ther. 310, 774 782.
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.310
, pp. 774-782
-
-
Muller, D.L.1
Unterwald, E.M.2
-
26
-
-
0030766528
-
Molecular and cellular basis of addiction
-
Nestler E. J. Aghajanian G. K. (1996) Molecular and cellular basis of addiction. Science 278, 58 63.
-
(1996)
Science
, vol.278
, pp. 58-63
-
-
Nestler, E.J.1
Aghajanian, G.K.2
-
27
-
-
0033559843
-
Cloning and characterization of RGS9-2: A striatal enriched alternatively spliced product of the RGS9 gene
-
Rahman Z., Gold S. J., Potenza M. N., Cowan C. W., Ni Y. G., He W., Wensel T. G. Nestler E. J. (1999) Cloning and characterization of RGS9-2: a striatal enriched alternatively spliced product of the RGS9 gene. J. Neurosci. 19, 2016 2026.
-
(1999)
J. Neurosci.
, vol.19
, pp. 2016-2026
-
-
Rahman, Z.1
Gold, S.J.2
Potenza, M.N.3
Cowan, C.W.4
Ni, Y.G.5
He, W.6
Wensel, T.G.7
Nestler, E.J.8
-
28
-
-
33646644504
-
Mu opioid receptor regulation and opioid responsiveness
-
Reahal K. M. Bohn L. M. (2006) Mu opioid receptor regulation and opioid responsiveness. AAPS 7, E587 E591.
-
(2006)
AAPS
, vol.7
-
-
Reahal, K.M.1
Bohn, L.M.2
-
29
-
-
0033962013
-
Involvement of mitogen-activated protein kinase in agonist-induced phosphorylation of the mu-opioid receptor in HEK 293 cells
-
Schmidt H., Schulz S., Klutzny M., Koch T., Handel M. Hollt V. (2000) Involvement of mitogen-activated protein kinase in agonist-induced phosphorylation of the mu-opioid receptor in HEK 293 cells. J. Neurochem. 74, 414 422.
-
(2000)
J. Neurochem.
, vol.74
, pp. 414-422
-
-
Schmidt, H.1
Schulz, S.2
Klutzny, M.3
Koch, T.4
Handel, M.5
Hollt, V.6
-
30
-
-
16344394786
-
Regulators of G protein signaling and drugs of abuse
-
Traynor J. R. Neubig R. R. (2005) Regulators of G protein signaling and drugs of abuse. Mol. Interv. 5, 30 41.
-
(2005)
Mol. Interv.
, vol.5
, pp. 30-41
-
-
Traynor, J.R.1
Neubig, R.R.2
-
31
-
-
0038383458
-
Regulated endocytosis of opioid receptors: Cellular mechanism and proposed roles in physiological adaptation to opiate drugs
-
Von Zastrow M., Svingos A., Haberstock-Debic H. Evans C. (2003) Regulated endocytosis of opioid receptors: cellular mechanism and proposed roles in physiological adaptation to opiate drugs. Curr. Opin. Neurobiol. 13, 348 353.
-
(2003)
Curr. Opin. Neurobiol.
, vol.13
, pp. 348-353
-
-
Von Zastrow, M.1
Svingos, A.2
Haberstock-Debic, H.3
Evans, C.4
-
32
-
-
0033179904
-
Functional dissociation of mu opioid receptor signaling and endocytosis: Implications for the biology of opiate tolerance and addiction
-
Whistler J. L., Chuang H., Chu P., Jan L. Y. von Zastrow M. (1999) Functional dissociation of mu opioid receptor signaling and endocytosis: implications for the biology of opiate tolerance and addiction. Neuron 23, 737 746.
-
(1999)
Neuron
, vol.23
, pp. 737-746
-
-
Whistler, J.L.1
Chuang, H.2
Chu, P.3
Jan, L.Y.4
Von Zastrow, M.5
|