-
1
-
-
33644857442
-
The structure of dimeric ROCK I reveals the mechanism for ligand selectivity
-
Jacobs M, Hayakawa K, Swenson L, Bellon S, Fleming M, Taslimi P, Doran J. The structure of dimeric ROCK I reveals the mechanism for ligand selectivity. J Biol Chem. 2006;281:260-260.
-
(2006)
J Biol Chem
, vol.281
, pp. 260-260
-
-
Jacobs, M.1
Hayakawa, K.2
Swenson, L.3
Bellon, S.4
Fleming, M.5
Taslimi, P.6
Doran, J.7
-
2
-
-
24144498411
-
Rho-kinase is an important therapeutic target in cardiovascular medicine
-
Shimokawa H, Takeshita A. Rho-kinase is an important therapeutic target in cardiovascular medicine. Arterioscler Thromb Vasc Biol. 2005;25:1767-1775.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 1767-1775
-
-
Shimokawa, H.1
Takeshita, A.2
-
3
-
-
26444561489
-
Rho/Rho kinase signal transduction pathway in cardiovascular disease and cardiovascular remodeling
-
Jalil JE, Lavandero S, Chiong M, Ocaranza MP. Rho/Rho kinase signal transduction pathway in cardiovascular disease and cardiovascular remodeling. Rev Esp Cardiol. 2005;58:951-961.
-
(2005)
Rev Esp Cardiol
, vol.58
, pp. 951-961
-
-
Jalil, J.E.1
Lavandero, S.2
Chiong, M.3
Ocaranza, M.P.4
-
4
-
-
0035316139
-
Involvement of Rho-kinase in hypertensive vascular disease: A novel therapeutic target in hypertension
-
Mukai Y, Shimokawa H, Matoba T, Kandabashi T, Satoh S, Hiroki J, Kaibuchi K, Takeshita A. Involvement of Rho-kinase in hypertensive vascular disease: a novel therapeutic target in hypertension. FASEB J. 2001;15:1062-1064.
-
(2001)
FASEB J
, vol.15
, pp. 1062-1064
-
-
Mukai, Y.1
Shimokawa, H.2
Matoba, T.3
Kandabashi, T.4
Satoh, S.5
Hiroki, J.6
Kaibuchi, K.7
Takeshita, A.8
-
5
-
-
0035150402
-
Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells
-
Fukata Y, Amano M, Kaibuchi K. Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells. Trends Pharmacol Sci. 2001;22:32-39.
-
(2001)
Trends Pharmacol Sci
, vol.22
, pp. 32-39
-
-
Fukata, Y.1
Amano, M.2
Kaibuchi, K.3
-
6
-
-
0032559362
-
Rho GTPase and the actin cytoskeleton
-
Hall A. Rho GTPase and the actin cytoskeleton. Science. 1998;279:509-514.
-
(1998)
Science
, vol.279
, pp. 509-514
-
-
Hall, A.1
-
7
-
-
0031048791
-
Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase
-
Amano M, Chihara K, Kimura K, Fukata Y, Nakamura N, Matsuura Y, Kaibuchi K. Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase. Science. 1997;275:1308-1311.
-
(1997)
Science
, vol.275
, pp. 1308-1311
-
-
Amano, M.1
Chihara, K.2
Kimura, K.3
Fukata, Y.4
Nakamura, N.5
Matsuura, Y.6
Kaibuchi, K.7
-
8
-
-
0035093056
-
Cytoskeletal effects of Rho-like small guanine nucleotide-binding proteins in the vascular system
-
van Nieuw Amerongen GP, van Hinsbergh VWM. Cytoskeletal effects of Rho-like small guanine nucleotide-binding proteins in the vascular system. Arterioscler Thromb Vasc Biol. 2001;21:300-311.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 300-311
-
-
van Nieuw Amerongen, G.P.1
van Hinsbergh, V.W.M.2
-
9
-
-
0033527623
-
Cell migration: Movin' on
-
Horwitz AR, Parsons JT. Cell migration: movin' on. Science. 1999;286:1102-1103.
-
(1999)
Science
, vol.286
, pp. 1102-1103
-
-
Horwitz, A.R.1
Parsons, J.T.2
-
10
-
-
0029791373
-
The small GTPase Rho: Cellular functions and signal transduction
-
Narumiya S. The small GTPase Rho: cellular functions and signal transduction. J Biochem (Tokyo). 1996;120:215-228.
-
(1996)
J Biochem (Tokyo)
, vol.120
, pp. 215-228
-
-
Narumiya, S.1
-
11
-
-
0037423816
-
Activation of Rho A and inhibition of myosin phosphatase as important components in hypertension in vascular smooth muscle
-
Seko T, Ito M, Kureishi Y, Okamoto R, Moriki N, Onishi K, Isaka N, Hartshorne DJ, Nakano T. Activation of Rho A and inhibition of myosin phosphatase as important components in hypertension in vascular smooth muscle. Circ Res. 2003;92:411-418.
-
(2003)
Circ Res
, vol.92
, pp. 411-418
-
-
Seko, T.1
Ito, M.2
Kureishi, Y.3
Okamoto, R.4
Moriki, N.5
Onishi, K.6
Isaka, N.7
Hartshorne, D.J.8
Nakano, T.9
-
12
-
-
4744347777
-
Activation of Rho/Rho kinase signaling pathway by reactive oxygen species in rat aorta
-
Jin L, Ying Z, Webb RC. Activation of Rho/Rho kinase signaling pathway by reactive oxygen species in rat aorta. Am J Physiol Heart Circ Physiol. 2004;287:1495-1500.
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.287
, pp. 1495-1500
-
-
Jin, L.1
Ying, Z.2
Webb, R.C.3
-
13
-
-
9644280885
-
Hypertension and RhoA/Rho kinase signaling in the vasculature
-
Lee DL, Clinton Webb R, Jin L. Hypertension and RhoA/Rho kinase signaling in the vasculature. Hypertension. 2004;44:796-799.
-
(2004)
Hypertension
, vol.44
, pp. 796-799
-
-
Lee, D.L.1
Clinton Webb, R.2
Jin, L.3
-
14
-
-
0033601250
-
Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphatase
-
Feng J, Ito M, Ichikawa K, Isaka N, Nishikawa M, Hartshorne DJ, Nakano T. Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphatase. J Biol Chem. 1999;274:37385-37390.
-
(1999)
J Biol Chem
, vol.274
, pp. 37385-37390
-
-
Feng, J.1
Ito, M.2
Ichikawa, K.3
Isaka, N.4
Nishikawa, M.5
Hartshorne, D.J.6
Nakano, T.7
-
15
-
-
16644383772
-
Rho and Rho kinase are involved in parathyroid hormone-stimulated protein kinase C alpha translocation and IL-6 promotor activity in osteoblast cells
-
Radeff JM, Nagy Z, Stern PH. Rho and Rho kinase are involved in parathyroid hormone-stimulated protein kinase C alpha translocation and IL-6 promotor activity in osteoblast cells. J Bone Mineral Res. 2004;19:1882-1891.
-
(2004)
J Bone Mineral Res
, vol.19
, pp. 1882-1891
-
-
Radeff, J.M.1
Nagy, Z.2
Stern, P.H.3
-
16
-
-
0035571072
-
Rho-kinase mediates angiotensin II-induced monocyte chemoattractant protein-1 expression in rat vascular smooth muscle cells
-
Funakoshi Y, Ichiki T, Shimokawa H, Egashira K, Kaibuchi K, Takeya M, Yoshimura T, Takeshita A. Rho-kinase mediates angiotensin II-induced monocyte chemoattractant protein-1 expression in rat vascular smooth muscle cells. Hypertension. 2001;38:100-104.
-
(2001)
Hypertension
, vol.38
, pp. 100-104
-
-
Funakoshi, Y.1
Ichiki, T.2
Shimokawa, H.3
Egashira, K.4
Kaibuchi, K.5
Takeya, M.6
Yoshimura, T.7
Takeshita, A.8
-
17
-
-
0035725015
-
-
Beswick R, Dorrance AM, Leite R, Webb RC. NADH/NADPH oxidase and enhanced superoxide production in the mineralocorticiod hypertensive rat. Hypertension. 2001;38:1107-1115.
-
Beswick R, Dorrance AM, Leite R, Webb RC. NADH/NADPH oxidase and enhanced superoxide production in the mineralocorticiod hypertensive rat. Hypertension. 2001;38:1107-1115.
-
-
-
-
18
-
-
7744232120
-
Association of increased phagocytic NADPH oxidase-dependent superoxide production with diminished nitric oxide generation in essential hypertension
-
Fortuño A, Olivan S, Beloqui O, San Jose G, Moreno MU, Diez J, Zalba G. Association of increased phagocytic NADPH oxidase-dependent superoxide production with diminished nitric oxide generation in essential hypertension. J Hypertens. 2004;22:2169-2175.
-
(2004)
J Hypertens
, vol.22
, pp. 2169-2175
-
-
Fortuño, A.1
Olivan, S.2
Beloqui, O.3
San Jose, G.4
Moreno, M.U.5
Diez, J.6
Zalba, G.7
-
19
-
-
0035041566
-
Critical role of Rho-kinase and MEK/ERK pathways for angiotensin II-induced plasminogen activator inhibitor-1 gene expression
-
Takeda K, Ichiki T, Tokunou T, Iino N, Fujii S, Kitabatake A, Shimokawa H, Takeshita A. Critical role of Rho-kinase and MEK/ERK pathways for angiotensin II-induced plasminogen activator inhibitor-1 gene expression. Arterioscler Thromb Vasc Biol. 2001;21:868-873.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 868-873
-
-
Takeda, K.1
Ichiki, T.2
Tokunou, T.3
Iino, N.4
Fujii, S.5
Kitabatake, A.6
Shimokawa, H.7
Takeshita, A.8
-
20
-
-
9144227431
-
Long-term inhibition of Rho-kinase suppresses neointimal formation after stent implantation in porcine coronary arteries. Involvement of multiple mechanisms
-
Matsumoto Y, Uwatoku T, Abe K, Oi K, Hattori T, Morishige K, Eto Y, Fukumoto Y, Nakamura K, Shibata Y, Matsuda T, Takeshita A, Shimokawa H. Long-term inhibition of Rho-kinase suppresses neointimal formation after stent implantation in porcine coronary arteries. Involvement of multiple mechanisms. Arterioscler Thromb Vasc Biol. 2004;24:181-186.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 181-186
-
-
Matsumoto, Y.1
Uwatoku, T.2
Abe, K.3
Oi, K.4
Hattori, T.5
Morishige, K.6
Eto, Y.7
Fukumoto, Y.8
Nakamura, K.9
Shibata, Y.10
Matsuda, T.11
Takeshita, A.12
Shimokawa, H.13
-
21
-
-
0346690256
-
Long-term treatment with a specific Rho-kinase inhibitor suppresses cardiac allograft vasculopathy in mice
-
Hattori T, Shimokawa H, Higashi M, Hiroki J, Mukai Y, Kaibuchi K, Takeshita A. Long-term treatment with a specific Rho-kinase inhibitor suppresses cardiac allograft vasculopathy in mice. Circ Res. 2004;94:46-52.
-
(2004)
Circ Res
, vol.94
, pp. 46-52
-
-
Hattori, T.1
Shimokawa, H.2
Higashi, M.3
Hiroki, J.4
Mukai, Y.5
Kaibuchi, K.6
Takeshita, A.7
-
22
-
-
0348109425
-
Reactive oxygen species in the vasculature: Molecular and cellular mechanisms
-
Taniyama Y, Griendling K. Reactive oxygen species in the vasculature: molecular and cellular mechanisms. Hypertension. 2003;42:1075-1081.
-
(2003)
Hypertension
, vol.42
, pp. 1075-1081
-
-
Taniyama, Y.1
Griendling, K.2
-
23
-
-
0036645303
-
Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase
-
Takemoto M, Sun J, Hiroki J, Shimokawa H, Liao JK. Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase. Circulation. 2002;106:57-62.
-
(2002)
Circulation
, vol.106
, pp. 57-62
-
-
Takemoto, M.1
Sun, J.2
Hiroki, J.3
Shimokawa, H.4
Liao, J.K.5
-
24
-
-
0344442916
-
AT1b receptor predominantly mediates contractions in major mouse blood vessels
-
Zhou Y, Chen Y, Dirksen WP, Morris M, Periasamy M. AT1b receptor predominantly mediates contractions in major mouse blood vessels. Circ Res. 2003;93:1089-1094.
-
(2003)
Circ Res
, vol.93
, pp. 1089-1094
-
-
Zhou, Y.1
Chen, Y.2
Dirksen, W.P.3
Morris, M.4
Periasamy, M.5
-
25
-
-
0142120102
-
Long-term inhibition of Rho-kinase suppresses angiotensin II-induced cardiovascular hypertrophy in rats in vivo. Effects on endothelial NAD(P)H oxidase system
-
Higashi M, Shimokawa H, Hattori T, Hiroki J, Mukai Y, Morikawa K, Ichiki T, Takahashi S, Takeshita A. Long-term inhibition of Rho-kinase suppresses angiotensin II-induced cardiovascular hypertrophy in rats in vivo. Effects on endothelial NAD(P)H oxidase system. Circ Res. 2003;93:767-775.
-
(2003)
Circ Res
, vol.93
, pp. 767-775
-
-
Higashi, M.1
Shimokawa, H.2
Hattori, T.3
Hiroki, J.4
Mukai, Y.5
Morikawa, K.6
Ichiki, T.7
Takahashi, S.8
Takeshita, A.9
-
26
-
-
0033984069
-
Involvement of Rho-kinase in angiotensin II-induced hypertrophy of rat vascular smooth muscle cells
-
Yamakawa T, Tanaka S, Numaguchi K, Yamakawa Y, Motley ED, Ichihara S, Inagami T. Involvement of Rho-kinase in angiotensin II-induced hypertrophy of rat vascular smooth muscle cells. Hypertension. 2000;35:313-318.
-
(2000)
Hypertension
, vol.35
, pp. 313-318
-
-
Yamakawa, T.1
Tanaka, S.2
Numaguchi, K.3
Yamakawa, Y.4
Motley, E.D.5
Ichihara, S.6
Inagami, T.7
-
27
-
-
0036005997
-
Genotypes of the renin-angiotensin-aldosterone system: On the search of cardiovascular diseases
-
Jalil JE, Ocaranza MP. Genotypes of the renin-angiotensin-aldosterone system: on the search of cardiovascular diseases. Rev Esp Cardiol. 2002;55:89-91.
-
(2002)
Rev Esp Cardiol
, vol.55
, pp. 89-91
-
-
Jalil, J.E.1
Ocaranza, M.P.2
-
28
-
-
0042835819
-
Levels of plasma angiotensin-(1-7) in patients with hypertension who have the angiotensin-I-converting enzyme deletion/deletion genotype
-
Jalil JE, Palomera C, Ocaranza MP, Godoy I, Roman M, Chiong M, Lavandero S. Levels of plasma angiotensin-(1-7) in patients with hypertension who have the angiotensin-I-converting enzyme deletion/deletion genotype. Am J Cardiol. 2003;92:749-751.
-
(2003)
Am J Cardiol
, vol.92
, pp. 749-751
-
-
Jalil, J.E.1
Palomera, C.2
Ocaranza, M.P.3
Godoy, I.4
Roman, M.5
Chiong, M.6
Lavandero, S.7
-
29
-
-
0036686961
-
Angiotensin I-converting enzyme insertion/ deletion polymorphism and adrenergic response to exercise in hypertensive patients
-
Jalil JE, Cordova S, Ocaranza M, Schumacher E, Braun S, Chamorro G, Fardella C, Lavandero S. Angiotensin I-converting enzyme insertion/ deletion polymorphism and adrenergic response to exercise in hypertensive patients. Med Sci Monit. 2002;8:CR566-CR571.
-
(2002)
Med Sci Monit
, vol.8
-
-
Jalil, J.E.1
Cordova, S.2
Ocaranza, M.3
Schumacher, E.4
Braun, S.5
Chamorro, G.6
Fardella, C.7
Lavandero, S.8
-
30
-
-
1842422888
-
Transforming growth factor-beta 1 production is correlated with genetically determined ACE expression in congenic rats: A possible link between ACE genotype and diabetic nephropathy
-
Pueyo ME, Challah M, Gauguier D, Louedec L, Philippe M, Gaertner R, Marre M, Michel JB, Jacob MP. Transforming growth factor-beta 1 production is correlated with genetically determined ACE expression in congenic rats: a possible link between ACE genotype and diabetic nephropathy. Diabetes. 2004;53:1111-1118.
-
(2004)
Diabetes
, vol.53
, pp. 1111-1118
-
-
Pueyo, M.E.1
Challah, M.2
Gauguier, D.3
Louedec, L.4
Philippe, M.5
Gaertner, R.6
Marre, M.7
Michel, J.B.8
Jacob, M.P.9
-
31
-
-
31944444434
-
Increased aortic NADPH oxidase activity in rats with genetically high angiotensin-converting enzyme levels
-
Jalil JE, Perez A, Ocaranza MP, Bargetto J, Galaz A, Lavandero S. Increased aortic NADPH oxidase activity in rats with genetically high angiotensin-converting enzyme levels. Hypertension. 2005;46:1362-1367.
-
(2005)
Hypertension
, vol.46
, pp. 1362-1367
-
-
Jalil, J.E.1
Perez, A.2
Ocaranza, M.P.3
Bargetto, J.4
Galaz, A.5
Lavandero, S.6
-
32
-
-
0036492363
-
Angiotensin I-converting enzyme gene polymorphism influences chronic hypertensive response in the rat Goldblatt model
-
Ocaranza MP, Piddo AM, Faundez P, Lavandero S, Jalil JE. Angiotensin I-converting enzyme gene polymorphism influences chronic hypertensive response in the rat Goldblatt model. J Hypertens. 2002;20:413-420.
-
(2002)
J Hypertens
, vol.20
, pp. 413-420
-
-
Ocaranza, M.P.1
Piddo, A.M.2
Faundez, P.3
Lavandero, S.4
Jalil, J.E.5
-
33
-
-
32944470823
-
Effect of hypertension on angiotensin-(1-7) levels in rats with different angiotensin-I converting enzyme polymorphism
-
Ocaranza MP, Palomera C, Roman M, Bargetto J, Lavandero S, Jalil JE. Effect of hypertension on angiotensin-(1-7) levels in rats with different angiotensin-I converting enzyme polymorphism. Life Sci. 2006;78:1535-1542.
-
(2006)
Life Sci
, vol.78
, pp. 1535-1542
-
-
Ocaranza, M.P.1
Palomera, C.2
Roman, M.3
Bargetto, J.4
Lavandero, S.5
Jalil, J.E.6
-
34
-
-
0035459162
-
Angiotensin I-converting enzyme modulates neutral endopeptidase activity in the rat
-
Oliveri C, Ocaranza MP, Campos X, Lavandero S, Jalil J. Angiotensin I-converting enzyme modulates neutral endopeptidase activity in the rat. Hypertension. 2001;38:650-654.
-
(2001)
Hypertension
, vol.38
, pp. 650-654
-
-
Oliveri, C.1
Ocaranza, M.P.2
Campos, X.3
Lavandero, S.4
Jalil, J.5
-
35
-
-
19244369841
-
Polymorphism in gene coding for ACE determines different development of myocardial fibrosis in rats
-
Ocaranza MP, Diaz-Araya G, Carreno JE, Munoz D, Riveros JP, Jalil JE, Lavandero S. Polymorphism in gene coding for ACE determines different development of myocardial fibrosis in rats. Am J Physiol. 2004;H286:498-506.
-
(2004)
Am J Physiol
, vol.H286
, pp. 498-506
-
-
Ocaranza, M.P.1
Diaz-Araya, G.2
Carreno, J.E.3
Munoz, D.4
Riveros, J.P.5
Jalil, J.E.6
Lavandero, S.7
-
36
-
-
0031809462
-
Angiotensin I-converting enzyme genotype influences arterial response to injury in normotensive rats
-
Challah M, Villard E, Philippe M, Ribadeau-Dumas A, Giraudeau B, Janiak P, Vilaine JP, Soubrier F, Michel JB. Angiotensin I-converting enzyme genotype influences arterial response to injury in normotensive rats. Arterioscler Thromb Vasc Biol. 1998;18:235-243.
-
(1998)
Arterioscler Thromb Vasc Biol
, vol.18
, pp. 235-243
-
-
Challah, M.1
Villard, E.2
Philippe, M.3
Ribadeau-Dumas, A.4
Giraudeau, B.5
Janiak, P.6
Vilaine, J.P.7
Soubrier, F.8
Michel, J.B.9
-
37
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram cuantities of protein utilizing the principle of protein-dye binding
-
Bradford MM. A rapid and sensitive method for the quantitation of microgram cuantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248-254.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
38
-
-
33750528156
-
Androgens potentiate renal vascular responses to angiotensin II via amplification of the Rho kinase signaling pathway
-
Song J, Kost CK Jr, Martin DS. Androgens potentiate renal vascular responses to angiotensin II via amplification of the Rho kinase signaling pathway. Cardiovasc Res. 2006;72:456-463.
-
(2006)
Cardiovasc Res
, vol.72
, pp. 456-463
-
-
Song, J.1
Kost Jr, C.K.2
Martin, D.S.3
-
39
-
-
33746539611
-
Involvements of Rho-kinase and TGF-beta pathways in aldosterone-induced renal injury
-
Sun GP, Kohno M, Guo P, Nagai Y, Miyata K, Fan YY, Kimura S, Kiyomoto H, Ohmori K, Li DT, Abe Y, Nishiyama A. Involvements of Rho-kinase and TGF-beta pathways in aldosterone-induced renal injury. J Am Soc Nephrol. 2006;17:2193-2201.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 2193-2201
-
-
Sun, G.P.1
Kohno, M.2
Guo, P.3
Nagai, Y.4
Miyata, K.5
Fan, Y.Y.6
Kimura, S.7
Kiyomoto, H.8
Ohmori, K.9
Li, D.T.10
Abe, Y.11
Nishiyama, A.12
-
40
-
-
34147189502
-
Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats
-
Oka M, Homma N, Taraseviciene-Stewart L, Morris KG, Kraskauskas D, Burns N, Voelkel NF, McMurtry IF. Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats. Circ Res. 2007;100:923-929.
-
(2007)
Circ Res
, vol.100
, pp. 923-929
-
-
Oka, M.1
Homma, N.2
Taraseviciene-Stewart, L.3
Morris, K.G.4
Kraskauskas, D.5
Burns, N.6
Voelkel, N.F.7
McMurtry, I.F.8
-
41
-
-
0035895333
-
Myocardial fibrosis in DOCA-salt hypertensive rats: Effect of endothelin ET(A) receptor antagonism
-
Ammarguellat F, Larouche I, Schiffrin EL. Myocardial fibrosis in DOCA-salt hypertensive rats: effect of endothelin ET(A) receptor antagonism. Circulation. 2001;103:319-324.
-
(2001)
Circulation
, vol.103
, pp. 319-324
-
-
Ammarguellat, F.1
Larouche, I.2
Schiffrin, E.L.3
-
42
-
-
34249301303
-
Development of Rho-kinase inhibitors for cardiovascular medicine
-
Shimokawa H, Rashid M. Development of Rho-kinase inhibitors for cardiovascular medicine. Trends Pharmacol Sci. 2007;28:296-302.
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 296-302
-
-
Shimokawa, H.1
Rashid, M.2
-
43
-
-
0036226356
-
Involvement of Rho-kinase phathway for angiotensin II induced plasminogen activator inhibitor-1 gene expression and cardiovascular remodeling in hypertensive rats
-
Kobayashi N, Nakano S, Mita SI, Kobayashi T, Honda T, Tsubokou Y, Matsuoka H. Involvement of Rho-kinase phathway for angiotensin II induced plasminogen activator inhibitor-1 gene expression and cardiovascular remodeling in hypertensive rats. J Pharmacol Exp Therap. 2002;301:459-466.
-
(2002)
J Pharmacol Exp Therap
, vol.301
, pp. 459-466
-
-
Kobayashi, N.1
Nakano, S.2
Mita, S.I.3
Kobayashi, T.4
Honda, T.5
Tsubokou, Y.6
Matsuoka, H.7
-
44
-
-
18244401416
-
Important role of Rho-kinase in the pathogenesis of cardiovascular inflammation and remodeling induced by long-term blockade of nitric oxide synthesis in rats
-
Kataoka C, Egashira K, Inoue S, Takemoto M, Ni W, Koyanagi M, Kitamoto S, Usui. Important role of Rho-kinase in the pathogenesis of cardiovascular inflammation and remodeling induced by long-term blockade of nitric oxide synthesis in rats. Hypertension. 2002;39:245-250.
-
(2002)
Hypertension
, vol.39
, pp. 245-250
-
-
Kataoka, C.1
Egashira, K.2
Inoue, S.3
Takemoto, M.4
Ni, W.5
Koyanagi, M.6
Kitamoto, S.7
Usui8
-
45
-
-
20144366571
-
Role of Rho-kinase and p27 in angiotensin II-induced vascular injury
-
Kanda T, Hayashi K, Wakino S, Homma K, Yoshioka K, Hasegawa K, Sugano N, Tatematsu S, Takamatsu I, Mitsuhashi T, Saruta T. Role of Rho-kinase and p27 in angiotensin II-induced vascular injury. Hypertension. 2005;45:724-729.
-
(2005)
Hypertension
, vol.45
, pp. 724-729
-
-
Kanda, T.1
Hayashi, K.2
Wakino, S.3
Homma, K.4
Yoshioka, K.5
Hasegawa, K.6
Sugano, N.7
Tatematsu, S.8
Takamatsu, I.9
Mitsuhashi, T.10
Saruta, T.11
-
46
-
-
20944444181
-
-
Wang Y, Martin-McNulty B, da Cunha V, Vincelette J, Lu X, Feng Q, Halks-Miller M, Mahmoudi M, Schroeder M, Subramanyam B, Tseng J, Deng G, Schirm S, Johns A, Kauser K, Dole WP, Light DR. Fasudil, a Rho-kinase inhibitor, attenuates angiotensin I-induced abdominal aortic aneurysm in apolipoprotein E-Deficient mice by inhibiting apoptosis and proteolysis. Circulation. 2005;111:2219-2226.
-
Wang Y, Martin-McNulty B, da Cunha V, Vincelette J, Lu X, Feng Q, Halks-Miller M, Mahmoudi M, Schroeder M, Subramanyam B, Tseng J, Deng G, Schirm S, Johns A, Kauser K, Dole WP, Light DR. Fasudil, a Rho-kinase inhibitor, attenuates angiotensin I-induced abdominal aortic aneurysm in apolipoprotein E-Deficient mice by inhibiting apoptosis and proteolysis. Circulation. 2005;111:2219-2226.
-
-
-
-
47
-
-
33845659817
-
Rho kinase inhibition improves endothelial function in human subjects with coronary artery disease
-
Nohria A, Grunert ME, Rikitake Y, Noma K, Prsic A, Ganz P, Liao JK, Creager MA. Rho kinase inhibition improves endothelial function in human subjects with coronary artery disease. Circ Res. 2006;99:1426-1432.
-
(2006)
Circ Res
, vol.99
, pp. 1426-1432
-
-
Nohria, A.1
Grunert, M.E.2
Rikitake, Y.3
Noma, K.4
Prsic, A.5
Ganz, P.6
Liao, J.K.7
Creager, M.A.8
-
48
-
-
33645370510
-
Vasodilatory effect of subsequent administration of fasudil, a Rho-kinase inhibitor, surpasses that of nitroglycerin at the concentric coronary stenosis in patients with stable angina pectoris
-
Otsuka T, Ibuki C, Suzuki T, Ishii K, Kodani E. Atarashi H, Kishida H, Takano T. Vasodilatory effect of subsequent administration of fasudil, a Rho-kinase inhibitor, surpasses that of nitroglycerin at the concentric coronary stenosis in patients with stable angina pectoris. Circ J. 2006;70:402-408.
-
(2006)
Circ J
, vol.70
, pp. 402-408
-
-
Otsuka, T.1
Ibuki, C.2
Suzuki, T.3
Ishii, K.4
Kodani, E.5
Atarashi, H.6
Kishida, H.7
Takano, T.8
-
49
-
-
33646763902
-
Rho kinases in cardiovascular physiology and pathophysiology
-
Loirand G, Guerin P, Pacaud P. Rho kinases in cardiovascular physiology and pathophysiology. Circ Res. 2006;98:322-334.
-
(2006)
Circ Res
, vol.98
, pp. 322-334
-
-
Loirand, G.1
Guerin, P.2
Pacaud, P.3
-
50
-
-
0345486977
-
Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham Heart Study
-
O'Donnell CJ, Lindpaintner K, Larson MG, Rao VS, Ordovas JM, Schaefer EJ, Myers RH, Levy D. Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham Heart Study. Circulation. 1998;97:1766-1772.
-
(1998)
Circulation
, vol.97
, pp. 1766-1772
-
-
O'Donnell, C.J.1
Lindpaintner, K.2
Larson, M.G.3
Rao, V.S.4
Ordovas, J.M.5
Schaefer, E.J.6
Myers, R.H.7
Levy, D.8
-
51
-
-
0034595316
-
Deletion allele of angiotensin-converting enzyme gene increases risk of essential hypertension in japanese men. The Suita Study
-
Higaki J, Baba S, Katsuya T, Sato N, Ishikawa K, Mannami T, Ogata J, Ogihara T. Deletion allele of angiotensin-converting enzyme gene increases risk of essential hypertension in japanese men. The Suita Study. Circulation. 2000;101:2060-2065.
-
(2000)
Circulation
, vol.101
, pp. 2060-2065
-
-
Higaki, J.1
Baba, S.2
Katsuya, T.3
Sato, N.4
Ishikawa, K.5
Mannami, T.6
Ogata, J.7
Ogihara, T.8
-
52
-
-
0030842473
-
D allele of the angiotensin I-converting enzyme is a major risk factor for restenosis after coronary stenting
-
Amant C, Bauters C, Bodart JC, Lablanche JM, Grollier G, Danchin N, Hamon M, Richard F, Helbecque N, McFadden EP, Amouyel P, Bertrand ME. D allele of the angiotensin I-converting enzyme is a major risk factor for restenosis after coronary stenting. Circulation. 1997;96:56-60.
-
(1997)
Circulation
, vol.96
, pp. 56-60
-
-
Amant, C.1
Bauters, C.2
Bodart, J.C.3
Lablanche, J.M.4
Grollier, G.5
Danchin, N.6
Hamon, M.7
Richard, F.8
Helbecque, N.9
McFadden, E.P.10
Amouyel, P.11
Bertrand, M.E.12
-
53
-
-
0033158360
-
D/D genotype of the gene for angiotensin converting enzyme as a risk factor for post-stent coronary restenosis
-
Guarda E, Fajuri A, Marchant E, Martinez A, Jalil J, Illanes G, Vecchiola A, Lazen R, Flores A, Barra V, Irarrazabal S, Ilabaca F. D/D genotype of the gene for angiotensin converting enzyme as a risk factor for post-stent coronary restenosis. Rev Esp Cardiol. 1999;52:475-480.
-
(1999)
Rev Esp Cardiol
, vol.52
, pp. 475-480
-
-
Guarda, E.1
Fajuri, A.2
Marchant, E.3
Martinez, A.4
Jalil, J.5
Illanes, G.6
Vecchiola, A.7
Lazen, R.8
Flores, A.9
Barra, V.10
Irarrazabal, S.11
Ilabaca, F.12
|