메뉴 건너뛰기




Volumn 110, Issue 5, 2007, Pages 1559-1569

Immunologic evidence for lack of heterologous protection following resolution of HCV in patients with non-genotype 1 infection

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT PROTEIN; VIRUS PROTEIN;

EID: 34548844159     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2007-01-069583     Document Type: Article
Times cited : (25)

References (63)
  • 1
    • 0038575483 scopus 로고    scopus 로고
    • Acute hepatitis C: High rate of both spontaneous and treatment-induced viral clearance
    • Gerlach JT, Diepolder HM, Zachoval R, et al. Acute hepatitis C: high rate of both spontaneous and treatment-induced viral clearance. Gastroenterology. 2003;125:80-88.
    • (2003) Gastroenterology , vol.125 , pp. 80-88
    • Gerlach, J.T.1    Diepolder, H.M.2    Zachoval, R.3
  • 2
    • 0037181727 scopus 로고    scopus 로고
    • Protection against persistence of hepatitis C
    • Mehta SH, Cox A, Hoover DR, et al. Protection against persistence of hepatitis C. Lancet. 2002;359:1478-1483.
    • (2002) Lancet , vol.359 , pp. 1478-1483
    • Mehta, S.H.1    Cox, A.2    Hoover, D.R.3
  • 3
    • 14944375587 scopus 로고    scopus 로고
    • Immunology of hepatitis B virus and hepatitis C virus infection
    • Rehermann B, Nascimbeni M. Immunology of hepatitis B virus and hepatitis C virus infection. Nat Rev Immunol. 2005;5:215-229.
    • (2005) Nat Rev Immunol , vol.5 , pp. 215-229
    • Rehermann, B.1    Nascimbeni, M.2
  • 5
    • 33749452020 scopus 로고    scopus 로고
    • Outcomes and Treatment of Acute Hepatitis C Virus Infection in a United States Population
    • Corey KE, Ross AS, Wurcel A, et al. Outcomes and Treatment of Acute Hepatitis C Virus Infection in a United States Population. Clin Gastroenterol Hepatol. 2006;4:1278-1282.
    • (2006) Clin Gastroenterol Hepatol , vol.4 , pp. 1278-1282
    • Corey, K.E.1    Ross, A.S.2    Wurcel, A.3
  • 6
    • 0029151623 scopus 로고
    • Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection
    • Diepolder HM, Zachoval R, Hoffmann RM, et al. Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection. Lancet. 1995;346:1006-1007.
    • (1995) Lancet , vol.346 , pp. 1006-1007
    • Diepolder, H.M.1    Zachoval, R.2    Hoffmann, R.M.3
  • 7
    • 17644444485 scopus 로고    scopus 로고
    • Analysis of successful immune responses in persons infected with hepatitis C virus
    • Lechner F, Wong DK, Dunbar PR, et al. Analysis of successful immune responses in persons infected with hepatitis C virus. J Exp Med. 2000;191:1499-1512.
    • (2000) J Exp Med , vol.191 , pp. 1499-1512
    • Lechner, F.1    Wong, D.K.2    Dunbar, P.R.3
  • 8
    • 0035914925 scopus 로고    scopus 로고
    • Determinants of viral clearance and persistence during acute hepatitis C virus infection
    • Thimme R, Oldach D, Chang KM, Steiger C, Ray SC, Chisari FV. Determinants of viral clearance and persistence during acute hepatitis C virus infection. J Exp Med. 2001;194:1395-1406.
    • (2001) J Exp Med , vol.194 , pp. 1395-1406
    • Thimme, R.1    Oldach, D.2    Chang, K.M.3    Steiger, C.4    Ray, S.C.5    Chisari, F.V.6
  • 9
    • 0035196927 scopus 로고    scopus 로고
    • Differential CD4(+) and CD8(+) T-cell responsiveness in hepatitis C virus infection
    • Chang KM, Thimme R, Melpolder JJ, et al. Differential CD4(+) and CD8(+) T-cell responsiveness in hepatitis C virus infection. Hepatology. 2001;33:267-276.
    • (2001) Hepatology , vol.33 , pp. 267-276
    • Chang, K.M.1    Thimme, R.2    Melpolder, J.J.3
  • 10
    • 24744453723 scopus 로고    scopus 로고
    • Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes
    • Schulze zur Wiesch J, Lauer GM, Day CL et al. Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes. J Immunol. 2005;175:3603-3613.
    • (2005) J Immunol , vol.175 , pp. 3603-3613
    • Schulze zur Wiesch, J.1    Lauer, G.M.2    Day, C.L.3
  • 11
    • 0036891826 scopus 로고    scopus 로고
    • Broad specificity of virus-specific CD4+ T-helper-cell responses in resolved hepatitis C virus infection
    • Day CL, Lauer GM, Robbins GK, et al. Broad specificity of virus-specific CD4+ T-helper-cell responses in resolved hepatitis C virus infection. J Virol. 2002;76:12584-12595.
    • (2002) J Virol , vol.76 , pp. 12584-12595
    • Day, C.L.1    Lauer, G.M.2    Robbins, G.K.3
  • 12
    • 23944467250 scopus 로고    scopus 로고
    • Adaptive immune responses in acute and chronic hepatitis C virus infection
    • Bowen DGC, Walker M. Adaptive immune responses in acute and chronic hepatitis C virus infection. Nature. 2005;436:946-952.
    • (2005) Nature , vol.436 , pp. 946-952
    • Bowen, D.G.C.1    Walker, M.2
  • 13
    • 23944481107 scopus 로고    scopus 로고
    • Unscrambling hepatitis C virus-host interactions
    • Chisari FV. Unscrambling hepatitis C virus-host interactions. Nature. 2005;436:930-932.
    • (2005) Nature , vol.436 , pp. 930-932
    • Chisari, F.V.1
  • 14
    • 9244255343 scopus 로고    scopus 로고
    • Cell-mediated immunity and the outcome of hepatitis C virus infection
    • Shoukry NH, Cawthon AG, Walker CM. Cell-mediated immunity and the outcome of hepatitis C virus infection. Annu Rev Microbiol. 2004;58:391-424.
    • (2004) Annu Rev Microbiol , vol.58 , pp. 391-424
    • Shoukry, N.H.1    Cawthon, A.G.2    Walker, C.M.3
  • 15
    • 0042905866 scopus 로고    scopus 로고
    • Subversion of immune responses by hepatitis C virus: Immunomodulatory strategies beyond evasion?
    • Hahn YS. Subversion of immune responses by hepatitis C virus: immunomodulatory strategies beyond evasion? Curr Opin Immunol. 2003;15:443-449.
    • (2003) Curr Opin Immunol , vol.15 , pp. 443-449
    • Hahn, Y.S.1
  • 16
    • 7444256169 scopus 로고    scopus 로고
    • Genetic diversity and evolution of hepatitis C virus-15 years on
    • Simmonds P. Genetic diversity and evolution of hepatitis C virus-15 years on. J Gen Virol. 2004;85:3173-3188.
    • (2004) J Gen Virol , vol.85 , pp. 3173-3188
    • Simmonds, P.1
  • 17
    • 23944452579 scopus 로고    scopus 로고
    • Prospects for a vaccine against the hepatitis C virus
    • Houghton M, Abrignani S. Prospects for a vaccine against the hepatitis C virus. Nature. 2005;436:961-966.
    • (2005) Nature , vol.436 , pp. 961-966
    • Houghton, M.1    Abrignani, S.2
  • 18
    • 0027225677 scopus 로고
    • Superinfection of heterologous hepatitis C virus in a patient with chronic type C hepatitis
    • Kao JH, Chen PJ, Lai MY, Chen DS. Superinfection of heterologous hepatitis C virus in a patient with chronic type C hepatitis. Gastroenterology. 1993;105:583-587.
    • (1993) Gastroenterology , vol.105 , pp. 583-587
    • Kao, J.H.1    Chen, P.J.2    Lai, M.Y.3    Chen, D.S.4
  • 19
    • 0029837003 scopus 로고    scopus 로고
    • Superinfection by homotypic virus in hepatitis C virus carriers: Studies on patients with post-transfusion hepatitis
    • Kao JH, Chen PJ, Wang JT, et al. Superinfection by homotypic virus in hepatitis C virus carriers: studies on patients with post-transfusion hepatitis. J Med Virol. 1996;50:303-308.
    • (1996) J Med Virol , vol.50 , pp. 303-308
    • Kao, J.H.1    Chen, P.J.2    Wang, J.T.3
  • 20
    • 0028158455 scopus 로고
    • Hepatitis C virus in multiple episodes of acute hepatitis in polytransfused thalassaemic children
    • Lai ME, Mazzoleni AP, Argiolu F, et al. Hepatitis C virus in multiple episodes of acute hepatitis in polytransfused thalassaemic children. Lancet. 1994;343:388-390.
    • (1994) Lancet , vol.343 , pp. 388-390
    • Lai, M.E.1    Mazzoleni, A.P.2    Argiolu, F.3
  • 21
    • 0033890784 scopus 로고    scopus 로고
    • Two successive hepatitis C virus infections in an intravenous drug user
    • Proust B, Dubois F, Bacq Y, et al. Two successive hepatitis C virus infections in an intravenous drug user. J Clin Microbiol. 2000;38:3125-3127.
    • (2000) J Clin Microbiol , vol.38 , pp. 3125-3127
    • Proust, B.1    Dubois, F.2    Bacq, Y.3
  • 22
    • 0347634389 scopus 로고    scopus 로고
    • Crossgenotype immunity to hepatitis C virus
    • Lanford RE, Guerra B, Chavez D, et al. Crossgenotype immunity to hepatitis C virus. J Virol. 2004;78:1575-1581.
    • (2004) J Virol , vol.78 , pp. 1575-1581
    • Lanford, R.E.1    Guerra, B.2    Chavez, D.3
  • 23
    • 27744438976 scopus 로고    scopus 로고
    • Protection against chronic hepatitis C virus infection after rechallenge with homologous, but not heterologous, genotypes in a chimpanzee model
    • Prince AM, Brotman B, Lee DH, et al. Protection against chronic hepatitis C virus infection after rechallenge with homologous, but not heterologous, genotypes in a chimpanzee model. J Infect Dis. 2005;192:1701-1709.
    • (2005) J Infect Dis , vol.192 , pp. 1701-1709
    • Prince, A.M.1    Brotman, B.2    Lee, D.H.3
  • 24
    • 0346734182 scopus 로고    scopus 로고
    • Conserved hierarchy of helper T cell responses in a chimpanzee during primary and secondary hepatitis C virus infections
    • Shoukry NH, Sidney J, Sette A, Walker CM. Conserved hierarchy of helper T cell responses in a chimpanzee during primary and secondary hepatitis C virus infections. J Immunol. 2004;172:483-492.
    • (2004) J Immunol , vol.172 , pp. 483-492
    • Shoukry, N.H.1    Sidney, J.2    Sette, A.3    Walker, C.M.4
  • 25
    • 0027959912 scopus 로고
    • Superinfection of chimpanzees carrying hepatitis C virus of genotype II/1b with that of genotype III/2a or I/1a
    • Okamoto H, Mishiro S, Tokita H, Tsuda F, Miyakawa Y, Mayumi M. Superinfection of chimpanzees carrying hepatitis C virus of genotype II/1b with that of genotype III/2a or I/1a. Hepatology. 1994;20:1131-1136.
    • (1994) Hepatology , vol.20 , pp. 1131-1136
    • Okamoto, H.1    Mishiro, S.2    Tokita, H.3    Tsuda, F.4    Miyakawa, Y.5    Mayumi, M.6
  • 26
    • 32244435842 scopus 로고    scopus 로고
    • A T-cell HCV vaccine eliciting effective immunity against heterologous virus challenge in chimpanzees
    • Folgori A, Capone S, Ruggeri L, et al. A T-cell HCV vaccine eliciting effective immunity against heterologous virus challenge in chimpanzees. Nat Med. 2006;12:190-197.
    • (2006) Nat Med , vol.12 , pp. 190-197
    • Folgori, A.1    Capone, S.2    Ruggeri, L.3
  • 27
    • 2442641285 scopus 로고    scopus 로고
    • Evidence for a relation between the viral load and genotype and hepatitis C virus-specific T cell responses
    • Hultgren C, Desombere I, Leroux-Roels G, et al. Evidence for a relation between the viral load and genotype and hepatitis C virus-specific T cell responses. J Hepatol. 2004;40:971-978.
    • (2004) J Hepatol , vol.40 , pp. 971-978
    • Hultgren, C.1    Desombere, I.2    Leroux-Roels, G.3
  • 28
    • 20044395103 scopus 로고    scopus 로고
    • T-cell response relative to genotype and ethnicity during antiviral therapy for chronic hepatitis C
    • Kaplan DE, Sugimoto K, Ikeda F, et al. T-cell response relative to genotype and ethnicity during antiviral therapy for chronic hepatitis C. Hepatology. 2005;41:1365-1375.
    • (2005) Hepatology , vol.41 , pp. 1365-1375
    • Kaplan, D.E.1    Sugimoto, K.2    Ikeda, F.3
  • 29
    • 2442702625 scopus 로고    scopus 로고
    • Interferon-alpha for hepatitis C: Antiviral or immunotherapy?
    • Diepolder HM. Interferon-alpha for hepatitis C: antiviral or immunotherapy? J Hepatol. 2004;40:1030-1031.
    • (2004) J Hepatol , vol.40 , pp. 1030-1031
    • Diepolder, H.M.1
  • 30
    • 0034120427 scopus 로고    scopus 로고
    • Clinical significance of hepatitis C virus genotypes
    • Zein NN. Clinical significance of hepatitis C virus genotypes. Clin Microbiol Rev. 2000;13:223-235.
    • (2000) Clin Microbiol Rev , vol.13 , pp. 223-235
    • Zein, N.N.1
  • 31
    • 0037234636 scopus 로고    scopus 로고
    • Evidence for lack of cross-genotype protection of CD4+ T cell responses during chronic hepatitis C virus infection
    • Harcourt GC, Lucas M, Godkin AJ, Kantzanou M, Phillips RE, Klenerman P. Evidence for lack of cross-genotype protection of CD4+ T cell responses during chronic hepatitis C virus infection. Clin Exp Immunol. 2003;131:122-129.
    • (2003) Clin Exp Immunol , vol.131 , pp. 122-129
    • Harcourt, G.C.1    Lucas, M.2    Godkin, A.J.3    Kantzanou, M.4    Phillips, R.E.5    Klenerman, P.6
  • 32
    • 18744382757 scopus 로고    scopus 로고
    • Strainspecific T-cell suppression and protective immunity in patients with chronic hepatitis C virus infection
    • Sugimoto K, Kaplan DE, Ikeda F, et al. Strainspecific T-cell suppression and protective immunity in patients with chronic hepatitis C virus infection. J Virol. 2005;79:6976-6983.
    • (2005) J Virol , vol.79 , pp. 6976-6983
    • Sugimoto, K.1    Kaplan, D.E.2    Ikeda, F.3
  • 33
    • 0033180411 scopus 로고    scopus 로고
    • Presence of multiple genotype-specific antibodies in patients with persistent infection with hepatitis C virus (HCV) of a single genotype: Evidence for transient or occult superinfection with HCV of different genotypes
    • Toyoda H, Fukuda Y, Hayakawa T, et al. Presence of multiple genotype-specific antibodies in patients with persistent infection with hepatitis C virus (HCV) of a single genotype: evidence for transient or occult superinfection with HCV of different genotypes. Am J Gastroenterol. 1999;94:2230-2236.
    • (1999) Am J Gastroenterol , vol.94 , pp. 2230-2236
    • Toyoda, H.1    Fukuda, Y.2    Hayakawa, T.3
  • 35
    • 34548845981 scopus 로고    scopus 로고
    • European Union, Accessed January 2
    • European Union. European HCV Database. http://euhcvdb.ibcp.fr/euHCVdb/. Accessed January 2, 2006.
    • (2006) European HCV Database
  • 36
    • 34548840098 scopus 로고    scopus 로고
    • National Institute of Allergies and Infectious Diseases, Accessed January 2, 2006
    • National Institute of Allergies and Infectious Diseases. HCV Virus Database Project. http://hcv-.lanl.gov/content/hcv-db/index. Accessed January 2, 2006.
    • HCV Virus Database Project
  • 37
    • 19944428565 scopus 로고    scopus 로고
    • CD8 epitope escape and reversion in acute HCV infection
    • Timm J, Lauer GM, Kavanagh DG, et al. CD8 epitope escape and reversion in acute HCV infection. J Exp Med. 2004;200:1593-1604.
    • (2004) J Exp Med , vol.200 , pp. 1593-1604
    • Timm, J.1    Lauer, G.M.2    Kavanagh, D.G.3
  • 38
    • 0028931257 scopus 로고
    • Comprehensive, serologically equivalent DNA typing for HLA-B by PCR using sequence-specific primers (PCR-SSP)
    • Bunce M, Fanning GC, Welsh KI. Comprehensive, serologically equivalent DNA typing for HLA-B by PCR using sequence-specific primers (PCR-SSP). Tissue Antigens. 1995;45:81-90.
    • (1995) Tissue Antigens , vol.45 , pp. 81-90
    • Bunce, M.1    Fanning, G.C.2    Welsh, K.I.3
  • 39
    • 0029618012 scopus 로고
    • Phototyping: Comprehensive DNA typing for HLA-A, B, C, DRB1, DRB3, DRB4, DRB5 and DQB1 by PCR with 144 primer mixes utilizing sequence-specific primers (PCR-SSP)
    • Bunce M, O'Neill CM, Barnardo MC, et al. Phototyping: comprehensive DNA typing for HLA-A, B, C, DRB1, DRB3, DRB4, DRB5 and DQB1 by PCR with 144 primer mixes utilizing sequence-specific primers (PCR-SSP). Tissue Antigens. 1995;46:355-367.
    • (1995) Tissue Antigens , vol.46 , pp. 355-367
    • Bunce, M.1    O'Neill, C.M.2    Barnardo, M.C.3
  • 40
    • 26444435730 scopus 로고    scopus 로고
    • Full-breadth analysis of CD8+ T-cell responses in acute hepatitis C virus infection and early therapy
    • Lauer GM, Lucas M, Timm J, et al. Full-breadth analysis of CD8+ T-cell responses in acute hepatitis C virus infection and early therapy. J Virol. 2005;79:12979-12988.
    • (2005) J Virol , vol.79 , pp. 12979-12988
    • Lauer, G.M.1    Lucas, M.2    Timm, J.3
  • 41
    • 25144508604 scopus 로고    scopus 로고
    • Minimal T-cell-stimulatory sequences and spectrum of HLA restriction of immunodominant CD4+ T-cell epitopes within hepatitis C virus NS3 and NS4 proteins
    • Gerlach JT, Ulsenheimer A, Gruner NH, et al. Minimal T-cell-stimulatory sequences and spectrum of HLA restriction of immunodominant CD4+ T-cell epitopes within hepatitis C virus NS3 and NS4 proteins. J Virol. 2005;79:12425-12433.
    • (2005) J Virol , vol.79 , pp. 12425-12433
    • Gerlach, J.T.1    Ulsenheimer, A.2    Gruner, N.H.3
  • 42
    • 0030790664 scopus 로고    scopus 로고
    • Immunodominant CD4+ T-cell epitope within nonstructural protein 3 in acute hepatitis C virus infection
    • Diepolder HM, Gerlach JT, Zachoval R, et al. Immunodominant CD4+ T-cell epitope within nonstructural protein 3 in acute hepatitis C virus infection. J Virol. 1997;71:6011-6019.
    • (1997) J Virol , vol.71 , pp. 6011-6019
    • Diepolder, H.M.1    Gerlach, J.T.2    Zachoval, R.3
  • 43
    • 0032870469 scopus 로고    scopus 로고
    • Conserved hepatitis C virus sequences are highly immunogenic for CD4(+) T cells: Implications for vaccine development
    • Lamonaca V, Missale G, Urbani S, et al. Conserved hepatitis C virus sequences are highly immunogenic for CD4(+) T cells: implications for vaccine development. Hepatology. 1999;30:1088-1098.
    • (1999) Hepatology , vol.30 , pp. 1088-1098
    • Lamonaca, V.1    Missale, G.2    Urbani, S.3
  • 44
    • 19944428565 scopus 로고    scopus 로고
    • CD8 epitope escape and reversion in acute HCV infection
    • Timm J, Lauer GM, Kavanagh DG, et al. CD8 epitope escape and reversion in acute HCV infection. J Exp Med. 2004;200:1593-1604.
    • (2004) J Exp Med , vol.200 , pp. 1593-1604
    • Timm, J.1    Lauer, G.M.2    Kavanagh, D.G.3
  • 46
    • 0347594006 scopus 로고    scopus 로고
    • Progress in defining CD4 helper cell responses in chronic viral infections
    • Day CLB, Walker D. Progress in defining CD4 helper cell responses in chronic viral infections. J Exp Med. 2003;198:1773-1777.
    • (2003) J Exp Med , vol.198 , pp. 1773-1777
    • Day, C.L.B.1    Walker, D.2
  • 48
    • 0030986358 scopus 로고    scopus 로고
    • A critical role for neutralizing- antibody-producing B cells, CD4(+) T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: Implications for adoptive immunotherapy of virus carriers
    • Planz O, Ehl S Furrer E, et al. A critical role for neutralizing- antibody-producing B cells, CD4(+) T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: implications for adoptive immunotherapy of virus carriers. Proc Natl Acad Sci U S A. 1997;94:6874-6879.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 6874-6879
    • Planz, O.1    Ehl, S.2    Furrer, E.3
  • 49
    • 0037432787 scopus 로고    scopus 로고
    • Requirement for CD4 T cell help in generating functional CD8 T cell memory
    • Shedlock DJ, Shen H. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science. 2003;300:337-339.
    • (2003) Science , vol.300 , pp. 337-339
    • Shedlock, D.J.1    Shen, H.2
  • 50
    • 0037442136 scopus 로고    scopus 로고
    • Role of CD4 T cell help and costimulation in CD8 T cell responses during Listeria monocytogenes infection
    • Shedlock DJ, Whitmire JK, Tan J, MacDonald AS, Ahmed R, Shen H. Role of CD4 T cell help and costimulation in CD8 T cell responses during Listeria monocytogenes infection. J Immunol. 2003;170:2053-2063.
    • (2003) J Immunol , vol.170 , pp. 2053-2063
    • Shedlock, D.J.1    Whitmire, J.K.2    Tan, J.3    MacDonald, A.S.4    Ahmed, R.5    Shen, H.6
  • 51
    • 0037432776 scopus 로고    scopus 로고
    • Defective CD8 T cell memory following acute infection without CD4 T cell help
    • Sun JCM, Bevan J. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science. 2003;300:339-342.
    • (2003) Science , vol.300 , pp. 339-342
    • Sun, J.C.M.1    Bevan, J.2
  • 52
    • 0030053663 scopus 로고    scopus 로고
    • CD4-deficient mice have reduced levels of memory cytotoxic T lymphocytes after immunization and show diminished resistance to subsequent virus challenge
    • von Herrath MG, Yokoyama M, Dockter J, Oldstone MB, Whitton JL. CD4-deficient mice have reduced levels of memory cytotoxic T lymphocytes after immunization and show diminished resistance to subsequent virus challenge. J Virol. 1996;70:1072-1079.
    • (1996) J Virol , vol.70 , pp. 1072-1079
    • von Herrath, M.G.1    Yokoyama, M.2    Dockter, J.3    Oldstone, M.B.4    Whitton, J.L.5
  • 53
    • 0037432736 scopus 로고    scopus 로고
    • Immunology: CD8 T cells remember with a little help
    • Kaech SM, Ahmed R. Immunology: CD8 T cells remember with a little help. Science. 2003;300:263-265.
    • (2003) Science , vol.300 , pp. 263-265
    • Kaech, S.M.1    Ahmed, R.2
  • 54
    • 15644366143 scopus 로고    scopus 로고
    • A vigorous virus-specific CD4+ T cell response may contribute to the association of HLA-DR13 with viral clearance in hepatitis B
    • Diepolder HM, Jung MC, Keller E, et al. A vigorous virus-specific CD4+ T cell response may contribute to the association of HLA-DR13 with viral clearance in hepatitis B. Clin Exp Immunol. 1998;113:244-251.
    • (1998) Clin Exp Immunol , vol.113 , pp. 244-251
    • Diepolder, H.M.1    Jung, M.C.2    Keller, E.3
  • 55
    • 33745497485 scopus 로고    scopus 로고
    • Early impairment of HCV-specific T-cell proliferation during acute infection leads to failure of viral clearance
    • Folgori A, Spada E, Pezzanera M, et al. Early impairment of HCV-specific T-cell proliferation during acute infection leads to failure of viral clearance. Gut. 2006;55:1012-1019.
    • (2006) Gut , vol.55 , pp. 1012-1019
    • Folgori, A.1    Spada, E.2    Pezzanera, M.3
  • 56
    • 0032832514 scopus 로고    scopus 로고
    • Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T-cell response in acute hepatitis C
    • Gerlach JT, Diepolder HM, Jung MC, et al. Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T-cell response in acute hepatitis C. Gastroenterology. 1999;117:933-941.
    • (1999) Gastroenterology , vol.117 , pp. 933-941
    • Gerlach, J.T.1    Diepolder, H.M.2    Jung, M.C.3
  • 57
    • 0038374730 scopus 로고    scopus 로고
    • Detection of functionally altered hepatitis C virus-specific CD4 T cells in acute and chronic hepatitis C
    • Ulsenheimer A, Gerlach JT, Gruener NH, et al. Detection of functionally altered hepatitis C virus-specific CD4 T cells in acute and chronic hepatitis C. Hepatology. 2003;37:1189-1198.
    • (2003) Hepatology , vol.37 , pp. 1189-1198
    • Ulsenheimer, A.1    Gerlach, J.T.2    Gruener, N.H.3
  • 58
    • 15444374647 scopus 로고    scopus 로고
    • Private aspects of heterologous immunity
    • Rehermann BE, Shin C. Private aspects of heterologous immunity. J Exp Med. 2005;201:667-670.
    • (2005) J Exp Med , vol.201 , pp. 667-670
    • Rehermann, B.E.1    Shin, C.2
  • 59
    • 0038379214 scopus 로고    scopus 로고
    • Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever
    • Mongkolsapaya J, Dejnirattisai W, Xu XN, et al. Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever. Nat Med. 2003;9:921-927.
    • (2003) Nat Med , vol.9 , pp. 921-927
    • Mongkolsapaya, J.1    Dejnirattisai, W.2    Xu, X.N.3
  • 60
    • 23444438390 scopus 로고    scopus 로고
    • Altered cytokine responses of dengue-specific CD4+ T cells to heterologous serotypes
    • Mangada MMA, Rothman L. Altered cytokine responses of dengue-specific CD4+ T cells to heterologous serotypes. J Immunol. 2005;175:2676-2683.
    • (2005) J Immunol , vol.175 , pp. 2676-2683
    • Mangada, M.M.A.1    Rothman, L.2
  • 61
    • 2142827156 scopus 로고    scopus 로고
    • Dengue: Defining protective versus pathologic immunity
    • Rothman AL. Dengue: defining protective versus pathologic immunity. J Clin Invest. 2004;113:946-951.
    • (2004) J Clin Invest , vol.113 , pp. 946-951
    • Rothman, A.L.1
  • 62
    • 3242759735 scopus 로고    scopus 로고
    • Host genetic determinants in hepatitis C virus infection
    • Yee LJ. Host genetic determinants in hepatitis C virus infection. Genes Immun. 2004;5:237-245.
    • (2004) Genes Immun , vol.5 , pp. 237-245
    • Yee, L.J.1
  • 63
    • 33746697713 scopus 로고    scopus 로고
    • Differential antigenic hierarchy associated with spontaneous recovery from hepatitis C virus infection: Implications for vaccine design
    • Smyk-Pearson S, Tester IA, Lezotte D, Sasaki AW, Lewinsohn DM, Rosen HR. Differential antigenic hierarchy associated with spontaneous recovery from hepatitis C virus infection: implications for vaccine design. J Infect Dis. 2006;194:454-463.
    • (2006) J Infect Dis , vol.194 , pp. 454-463
    • Smyk-Pearson, S.1    Tester, I.A.2    Lezotte, D.3    Sasaki, A.W.4    Lewinsohn, D.M.5    Rosen, H.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.