Take your "M" time

Cell Cycle

Volumn 6, Issue 17, 2007, Pages 2087-2090

  Baldassarre, Gustavo ^a   Croce, Carlo M ^b   Vecchione, Andrea ^b,c  

^a CENTRO DI RIFERIMENTO ONCOLOGICO   (Italy)

^b OHIO STATE UNIVERSITY   (United States)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Aneuploidia; CDC25C; cdk1 activity; lzts1; Mitosis; Proteasomal degradation

Indexed keywords

CYCLIN B1;

ALLELE; APOPTOSIS; CARCINOGENESIS; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CHROMOSOME 8P; DNA DAMAGE; FEZ1 GENE; GENE DELETION; GENE EXPRESSION; GENE OVEREXPRESSION; MITOSIS; NONHUMAN; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; REVIEW; TUMOR SUPPRESSOR GENE;

MUS;

EID: 34548833816     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.6.17.4628     Document Type: Review

References (40)

1. Pines J. Mitosis: A matter of getting rid of the right protein at the right time. Trends Cell Biol 2006; 16:55-63.
2. Nigg EA. Mitotic kinases as regulators of cell division and its checkpoints. Nat Rev Mol Cell Rev Mol Biol 2001; 2:21-32.
3. 2/M transition. Biochim Biophys Acta 2001; 1519:1-12.
4. Sha W, Moore J, Chen K, Lassaletta AD, Yi CS, Tyson JJ, Sible JC. Hysteresis drives cell-cy- Sha W, cycle transitions in Xenopus laevis egg extracts. Proc Natl Acad Sci USA 2003; 100:975-80.
5. Pomerening JR, Sontag ED, Ferrell Jr JE. Building a cell cycle oscillator: Hysteresis and bistability in the activation of Cdc2. Nat Cell Biol 2003; 5:346-51.
6. Musacchio A, Hardwick KG. The spindle checkpoint: Structural insights into dynamic signalling. Nat Rev Mol Cell Biol 2002; 3(10):731-41.
7. Weaver BA, Cleveland DW. Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death. Cancer Cell 2005; 8:7-12.
8. Michel LS, Liberal V, Chatterjee A, Kirchwegger R, Pasche B, Gerald W, Dobles M, Sorger PK, Murty VV, Benezra R. MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells. Nature 2001; 409:355-9.
9. Cimini D, Moree B, Canman JC, Salmon ED. Merotelic kinetochore orientation occurs frequently during early mitosis in mammalian tissue cells and error correction is achieved by two different mechanisms. J Cell Sci 2003; 116:4213-25.
10. Stegmeier F, Rape M, Draviam VM, Nalepa G, Sowa ME, Ang XL, McDonald IIIrd ER, Li MZ, Hannon GJ, Sorger PK, Kirschner MW, Harper JW, Elledge SJ. Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities. Nature 2007; 446:876-81.
11. Reddy SK, Rape M, Margansky WA, Kirschner MW. Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation. Nature 2007; 446:921-5.
12. Draviam VM, Stegmeier F, Nalepa G, Sowa ME, Chen J, Liang A, Hannon GJ, Sorger PK, Harper JW, Elledge SJ. A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling. Nat Cell Biol 2007; 9:556-64.
13. Vecchione A, Baldassarre G, Ishii H, Nicoloso MS, Belletti B, Petrocca F, Zanesi N, Fong LY, Battista S, Guarnieri D, Baffa R, Alder H, Farber JL, Donovan PJ, Croce CM. Fez1/Lzts1 absence impairs Cdk1/Cdc25C interaction during mitosis and predisposes mice to cancer development. Cancer Cell 2007; 11:275-89.
14. Ishii H, Baffa R, Numata S, Murakumo Y, Rattan S, Inoue H, Mori M, Fidanza V, Alder H, Croce CM. The FEZ1 gene at chromosome 8p22 encodes a leucine-zipper protein, and its expression is altered in multiple human tumors. Proc Natl Acad Sci USA 1999; 96:3928-33.
15. Vocke CD, Pozzatti RO, Bostwick DG, Florence CD, Jennings SB, Strup SE, Duray PH, Liotta LA, Emmert-Buck MR, Linehan WM. Analysis of 99 microdissected prostate carcinomas reveals a high frequency of allelic loss on chromosome 8p12-21. Cancer Res 1996; 56:2411-6.
16. Wagner U, Bubendorf L, Gasser TC, Moch H, Gorog JP, Richter J, Mihatsch MJ, Waldman FM, Sauter G. Chromosome 8p deletions are associated with invasive tumor growth in urinary bladder cancer. Am J Pathol 1997; 151:753-9.
17. Anbazhagan R, Fujii H, Gabrielson E. Allelic loss of chromosomal arm 8p in breast cancer progression. Am J Pathol 1998; 152:815-9.
18. El-Naggar AK, Coombes MM, Batsakis JG, Hong WK, Goepfert H, Kagan J. Localization of chromosome 8p regions involved in early tumorigenesis of oral and laryngeal squamous carcinoma. Oncogene 1998; 16:2983-7.
19. Cabeza-Arvelaiz Y, Sepulveda JL, Lebovitz RM, Thompson TC, Chinault AC. Functional identification of LZTS1 as a candidate prostate tumor suppressor gene on human chromosome 8p22. Oncogene 2001; 20:4169-79.
20. Vecchione A, Ishii H, Shiao YH, Trapasso F, Rugge M, Alder H, Croce CM, Baffa, R. Altered expression of Fez1 protein in gastric carcinoma. Clin Cancer Res 2001; 7:1546-52.
21. Vecchione A, Ishii H, Baldassarre G, Bassi P, Trapasso F, Alder H, Pagano F, Gomella LG, Croce CM, Baffa R. FEZ1/LZTS1 is down-regulated in high-grade bladder cancer, and its restoration suppresses tumorigenicity in transitional cell carcinoma cells. Am J Pathol 2002; 160:1345-52.
22. Toyooka S, Fukuyama Y, Wistuba II, Tockman MS, Minna JD, Gazdar AF. Differential expression of FEZ1/LZTS1 gene in lung cancers and their cell cultures. Clin Cancer Res 2002; 8:2292-7.
23. Ono K, Uzawa K, Nakatsuru M, Shiiba M, Mochida Y, Tada A, Bukawa H, Miyakawa A, Yokoe H, Tanzawa H. Down-regulation of FEZ1/LZTS1 gene with frequent loss of heterozigosity in oral squamous cell carcinomas. Int J Oncol 2003; 23:297-302.
24. Nonaka D, Fabbri A, Roz L, Mariani L, Vecchione A, Moore GW, Tavecchio L, Croce CM, Sozzi G. Reduced FEZ1/LZTS1 expression and outcome prediction in lung cancer. Cancer Res 2005; 65:1207-12.
25. Chen W, Salto-Tellez M, Palanisamy N, Ganesan K, Hou Q, Tan LK, Sii LH, Ito K, Tan B, Wu J, Tay A, Tan KC, Ang E, Tan BK, Tan PH, Ito Y, Tan P. Targets of genome copy number reduction in primary breast cancers identified by integrative genomics. Genes Chromosomes Cancer 2007; 46:288-301.
26. Ishii H, Vecchione A, Murakumo Y, Baldassarre G, Numata S, Trapasso F, Alder H, Baffa R, Croce CM. FEZ1/LZTS1 gene at 8p22 suppresses cancer cell growth and regulates mitosis. Proc Natl Acad Sci USA 2001; 98:10374-9.
27. Chang DC, Xu N, Luo KQ. Degradation of cyclin B is required for the onset of anaphase in mammalian cells. J Biol Chem 2003; 278:37865-73.
28. Clute P, Pines J. Temporal and spatial control of cyclin B1 destruction in metaphase. Nat Cell Biol 1999; 1:82-7.
29. Seong YS, Min C, Li L, Yang JY, Kim SY, Cao X, Kim K, Yuspa SH, Chung HH, Lee KS. Characterization of a novel cyclin-dependent kinase 1 inhibitor, BMI-1026. Cancer Res 2003; 63:7384-91.
30. Niiya F, Xie X, Lee KS, Inoue H, Miki T. Inhibition of cyclin-dependent kinase 1 induces cytokinesis without chromosome segregation in an ECT2 and MgcRacGAP-dependent manner. J Biol Chem 2005; 280:36502-9.
31. Potapova TA, Daum JR, Pittman BD, Hudson JR, Jones TN, Satinover DL, Stukenberg PT, Gorbsky GJ. The reversibility of mitotic exit in vertebrate cells. Nature 2006; 440:954-8.
32. Vassilev LT, Tovar C, Chen S, Knezevic D, Zhao X, Sun H, Heimbrook DC, Chen L. Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1. Proc Natl Acad Sci USA 2006; 103:10660-5.
33. Chen MS, Hurov J, White LS, Woodford-Thomas T, Piwnica-Worms H. Absence of apparent phenotype in mice lacking Cdc25C protein phosphatase. Mol Cell Biol 2001; 21:3853-61.
34. Lindqvist A, Kallstrom H, Lundgren A, Barsoum E, Rosenthal CK. Cdc25B cooperates with Cdc25A to induce mitosis but has a unique role in activating cyclin B1-Cdk1 at the centrosome. J Cell Biol 2005; 171:35-45.
35. Rodrigues MA, Gomes DA, Leite MF, Grant W, Zhang L, Lam W, Cheng YC, Bennett AM, Nathanson MH. Nucleoplasmic calcium is required for cell proliferation. J Biol Chem 2007; In press.
36. Yu J, Zhao Y, Li Z, Galas S, Goldberg ML. Greatwall kinase participates in the CDC2 autoregulatory loop in Xenopus egg extracts. Mol Cell 2006; 22:83-91.
37. Song MS, Song SJ, Ayad NG, Chang JS, Lee JH, Hong HK, Lee H, Choi N, Kim J, Kim H, et al. The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex. Nat Cell Biol 2004; 6:129-37.
38. Carnero A. Targeting the cell cycle for cancer therapy. Br J Cancer 2002; 87:129-33.
39. Weaver BA, Silk AD, Montagna C, Verdier-Pinard P, Cleveland DW. Aneuploidy acts both oncogenically and as a tumor suppressor. Cancer Cell 2007; 11:25-36.
40. Sotillo R, Hernando E, Diaz-Rodriguez E, Teruya-Feldstein J, Cordon-Cardo C, Lowe SW, Benezra R. Mad2 overexpression promotes aneuploidy and tumorigenesis in mice. Cancer Cell 2007; 11:9-23.