Enantiomerically pure synthesis of β-substituted γ- butyrolactones: A key intermediate to concise synthesis of pregabalin

Journal of Organic Chemistry

Volumn 72, Issue 19, 2007, Pages 7390-7393

  Ok, Taedong ^a   Jeon, Aram ^a   Lee, Joohee ^a   Jung, Hak Lim ^b   Chang, Seop Hong ^b   Lee, Hee Seung ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b Korea University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BUTANE; DERIVATIVES; ENANTIOMERS; NUCLEOPHILES; SUBSTITUTION REACTIONS; SYNTHESIS (CHEMICAL);

BIOLOGICALLY ACTIVE COMPOUNDS; BUTYROLACTONES; ENANTIOMERICALLY PURE SYNTHESIS; GAMMA AMINOBUTYRIC ACID (GABA);

BIOACTIVITY;

GAMMA BUTYROLACTONE DERIVATIVE; PREGABALIN;

ARTICLE; CHIRALITY; CRYSTAL STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; REACTION ANALYSIS; STEREOCHEMISTRY;

4-BUTYROLACTONE; ANTICONVULSANTS; CRYSTALLOGRAPHY, X-RAY; GAMMA-AMINOBUTYRIC ACID; STEREOISOMERISM;

EID: 34548792285     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0709605     Document Type: Article

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