-
1
-
-
0036776370
-
Regulation of thymocyte differentiation: Pre-TCR signals and β-selection
-
Michie, A. M., and J. C. Zuniga-Pflucker. 2002. Regulation of thymocyte differentiation: pre-TCR signals and β-selection. Semin. Immunol. 14: 311-323.
-
(2002)
Semin. Immunol
, vol.14
, pp. 311-323
-
-
Michie, A.M.1
Zuniga-Pflucker, J.C.2
-
2
-
-
0033119330
-
Pleiotropic changes controlled by the pre-T-cell receptor
-
von Boehmer, H., I. Aifantis, J. Feinberg, O. Lechner, C. Saint-Ruf, U. Walter, J. Buer, and O. Azogui. 1999. Pleiotropic changes controlled by the pre-T-cell receptor. Curr. Opin. Immunol. 11: 135-142.
-
(1999)
Curr. Opin. Immunol
, vol.11
, pp. 135-142
-
-
von Boehmer, H.1
Aifantis, I.2
Feinberg, J.3
Lechner, O.4
Saint-Ruf, C.5
Walter, U.6
Buer, J.7
Azogui, O.8
-
3
-
-
0030294283
-
Fyn can partially substitute for Lck in T lymphocyte development
-
Groves, T., P. Smiley, M. P. Cooke, K. Forbush, R. M. Perlmutter, and C. J. Guidos. 1996. Fyn can partially substitute for Lck in T lymphocyte development. Immunity 5: 417-428.
-
(1996)
Immunity
, vol.5
, pp. 417-428
-
-
Groves, T.1
Smiley, P.2
Cooke, M.P.3
Forbush, K.4
Perlmutter, R.M.5
Guidos, C.J.6
-
4
-
-
0030293791
-
αβ T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases
-
van Oers, N. S., B. Lowin-Kropf, D. Finlay, K. Connolly, and A. Weiss. 1996. αβ T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases. Immunity 5: 429-436.
-
(1996)
Immunity
, vol.5
, pp. 429-436
-
-
van Oers, N.S.1
Lowin-Kropf, B.2
Finlay, D.3
Connolly, K.4
Weiss, A.5
-
5
-
-
0030886836
-
The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling
-
Cheng, A. M., I. Negishi, S. J. Anderson, A. C. Chan, J. Bolen, D. Y. Loh, and T. Pawson. 1997. The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling. Proc. Natl. Acad. Sci. USA 94: 9797-9801.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9797-9801
-
-
Cheng, A.M.1
Negishi, I.2
Anderson, S.J.3
Chan, A.C.4
Bolen, J.5
Loh, D.Y.6
Pawson, T.7
-
6
-
-
0032542350
-
Gads is a novel SH2 and SH3 domain-containing adaptor protein that binds to tyrosine-phosphorylated Shc
-
Liu, S. K., and C. J. McGlade. 1998. Gads is a novel SH2 and SH3 domain-containing adaptor protein that binds to tyrosine-phosphorylated Shc. Oncogene 17: 3073-3082.
-
(1998)
Oncogene
, vol.17
, pp. 3073-3082
-
-
Liu, S.K.1
McGlade, C.J.2
-
7
-
-
0032534809
-
Mona, a novel hematopoietic-specific adaptor interacting with the macrophage colony-stimulating factor receptor, is implicated in monocyte/macrophage development
-
Bourette, R. P., S. Arnaud, G. M. Myles, J. P. Blanchet, L. R. Rohrschneider, and G. Mouchiroud. 1998. Mona, a novel hematopoietic-specific adaptor interacting with the macrophage colony-stimulating factor receptor, is implicated in monocyte/macrophage development. EMBO J. 17: 7273-7281.
-
(1998)
EMBO J
, vol.17
, pp. 7273-7281
-
-
Bourette, R.P.1
Arnaud, S.2
Myles, G.M.3
Blanchet, J.P.4
Rohrschneider, L.R.5
Mouchiroud, G.6
-
8
-
-
0033583420
-
GrpL, a Grb2-related adaptor protein, interacts with SLP-76 to regulate nuclear factor of activated T cell activation
-
Law, C. L., M. K. Ewings, P. M. Chaudhary, S. A. Solow, T. J. Yun, A. J. Marshall, L. Hood, and E. A. Clark. 1999. GrpL, a Grb2-related adaptor protein, interacts with SLP-76 to regulate nuclear factor of activated T cell activation. J. Exp. Med. 189: 1243-1253.
-
(1999)
J. Exp. Med
, vol.189
, pp. 1243-1253
-
-
Law, C.L.1
Ewings, M.K.2
Chaudhary, P.M.3
Solow, S.A.4
Yun, T.J.5
Marshall, A.J.6
Hood, L.7
Clark, E.A.8
-
9
-
-
0033519283
-
Grf40, A novel Grb2 family member, is involved in T cell signaling through interaction with SLP-76 and LAT
-
Asada, H., N. Ishii, Y. Sasaki, K. Endo, H. Kasai, N. Tanaka, T. Takeshita, S. Tsuchiya, T. Konno, and K. Sugamura. 1999. Grf40, A novel Grb2 family member, is involved in T cell signaling through interaction with SLP-76 and LAT. J. Exp. Med. 189: 1383-1390.
-
(1999)
J. Exp. Med
, vol.189
, pp. 1383-1390
-
-
Asada, H.1
Ishii, N.2
Sasaki, Y.3
Endo, K.4
Kasai, H.5
Tanaka, N.6
Takeshita, T.7
Tsuchiya, S.8
Konno, T.9
Sugamura, K.10
-
10
-
-
0034041979
-
GRID: A novel Grb-2-related adapter protein that interacts with the activated T cell costimulatory receptor CD28
-
Ellis, J. H., C. Ashman, M. N. Burden, K. E. Kilpatrick, M. A. Morse, and P. A. Hamblin. 2000. GRID: a novel Grb-2-related adapter protein that interacts with the activated T cell costimulatory receptor CD28. J. Immunol. 164: 5805-5814.
-
(2000)
J. Immunol
, vol.164
, pp. 5805-5814
-
-
Ellis, J.H.1
Ashman, C.2
Burden, M.N.3
Kilpatrick, K.E.4
Morse, M.A.5
Hamblin, P.A.6
-
11
-
-
17444390883
-
Expression and function of the adaptor protein Gads in murine B cells
-
Yankee, T. M., K. E. Draves, and E. A. Clark. 2005. Expression and function of the adaptor protein Gads in murine B cells. Eur. J. Immunol. 35: 1184-1192.
-
(2005)
Eur. J. Immunol
, vol.35
, pp. 1184-1192
-
-
Yankee, T.M.1
Draves, K.E.2
Clark, E.A.3
-
12
-
-
0032563256
-
Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76
-
Pivniouk, V., E. Tsitsikov, P. Swinton, G. Rathbun, F. W. Alt, and R. S. Geha. 1998. Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76. Cell 94: 229-238.
-
(1998)
Cell
, vol.94
, pp. 229-238
-
-
Pivniouk, V.1
Tsitsikov, E.2
Swinton, P.3
Rathbun, G.4
Alt, F.W.5
Geha, R.S.6
-
13
-
-
0032540906
-
Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development
-
Clements, J. L., B. Yang, S. E. Ross-Barta, S. L. Eliason, R. F. Hrstka, R. A. Williamson, and G. A. Koretzky. 1998. Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development. Science 281: 416-419.
-
(1998)
Science
, vol.281
, pp. 416-419
-
-
Clements, J.L.1
Yang, B.2
Ross-Barta, S.E.3
Eliason, S.L.4
Hrstka, R.F.5
Williamson, R.A.6
Koretzky, G.A.7
-
14
-
-
0033103833
-
Essential role of LAT in T cell development
-
Zhang, W., C. L. Sommers, D. N. Burshtyn, C. C. Stebbins, J. B. DeJarnette, R. P. Trible, A. Grinberg, H. C. Tsay, H. M. Jacobs, C. M. Kessler, et al. 1999. Essential role of LAT in T cell development. Immunity 10: 323-332.
-
(1999)
Immunity
, vol.10
, pp. 323-332
-
-
Zhang, W.1
Sommers, C.L.2
Burshtyn, D.N.3
Stebbins, C.C.4
DeJarnette, J.B.5
Trible, R.P.6
Grinberg, A.7
Tsay, H.C.8
Jacobs, H.M.9
Kessler, C.M.10
-
15
-
-
0035831340
-
Requirement for the SLP-76 adaptor GADS in T cell development
-
Yoder, J., C. Pham, Y. M. Iizuka, O. Kanagawa, S. K. Liu, J. McGlade, and A. M. Cheng. 2001. Requirement for the SLP-76 adaptor GADS in T cell development. Science 291: 1987-1991.
-
(2001)
Science
, vol.291
, pp. 1987-1991
-
-
Yoder, J.1
Pham, C.2
Iizuka, Y.M.3
Kanagawa, O.4
Liu, S.K.5
McGlade, J.6
Cheng, A.M.7
-
16
-
-
3242803474
-
The Gads (GrpL) adaptor protein regulates T cell homeostasis
-
Yankee, T. M., T. J. Yun, K. E. Draves, K. Ganesh, M. J. Bevan, K. Murali-Krishna, and E. A. Clark. 2004. The Gads (GrpL) adaptor protein regulates T cell homeostasis. J. Immunol. 173: 1711-1720.
-
(2004)
J. Immunol
, vol.173
, pp. 1711-1720
-
-
Yankee, T.M.1
Yun, T.J.2
Draves, K.E.3
Ganesh, K.4
Bevan, M.J.5
Murali-Krishna, K.6
Clark, E.A.7
-
17
-
-
0036916440
-
Induction of T cell development from hematopoietic progenitor cells by δ-like-1 in vitro
-
Schmitt, T. M., and J. C. Zuniga-Pflucker. 2002. Induction of T cell development from hematopoietic progenitor cells by δ-like-1 in vitro. Immunity 17: 749-756.
-
(2002)
Immunity
, vol.17
, pp. 749-756
-
-
Schmitt, T.M.1
Zuniga-Pflucker, J.C.2
-
18
-
-
33747605056
-
Visualization of the earliest steps of γδ T cell development in the adult thymus
-
Prinz, I., A. Sansoni, A. Kissenpfennig, L. Ardouin, M. Malissen, and B. Malissen. 2006. Visualization of the earliest steps of γδ T cell development in the adult thymus. Nat. Immunol. 7: 995-1003.
-
(2006)
Nat. Immunol
, vol.7
, pp. 995-1003
-
-
Prinz, I.1
Sansoni, A.2
Kissenpfennig, A.3
Ardouin, L.4
Malissen, M.5
Malissen, B.6
-
19
-
-
4043147851
-
- T cells in the thymus
-
- T cells in the thymus. J. Immunol. 173: 2253-2261.
-
(2004)
J. Immunol
, vol.173
, pp. 2253-2261
-
-
Zheng, X.1
Gao, J.X.2
Chang, X.3
Wang, Y.4
Liu, Y.5
Wen, J.6
Zhang, H.7
Zhang, J.8
Liu, Y.9
Zheng, P.10
-
20
-
-
0034989139
-
Suppression of thymic development by the dominant-negative form of Gads
-
Kikuchi, K., Y. Kawasaki, N. Ishii, Y. Sasaki, H. Asao, T. Takeshita, I. Miyoshi, N. Kasai, and K. Sugamura. 2001. Suppression of thymic development by the dominant-negative form of Gads. Int. Immunol. 13: 777-783.
-
(2001)
Int. Immunol
, vol.13
, pp. 777-783
-
-
Kikuchi, K.1
Kawasaki, Y.2
Ishii, N.3
Sasaki, Y.4
Asao, H.5
Takeshita, T.6
Miyoshi, I.7
Kasai, N.8
Sugamura, K.9
-
21
-
-
0027153201
-
- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression
-
- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. J. Immunol. 150: 4244-4252.
-
(1993)
J. Immunol
, vol.150
, pp. 4244-4252
-
-
Godfrey, D.I.1
Kennedy, J.2
Suda, T.3
Zlotnik, A.4
-
22
-
-
0029072262
-
+) thymocytes in normal and genetically modified mice
-
+) thymocytes in normal and genetically modified mice. J. Immunol. 154: 5103-5113.
-
(1995)
J. Immunol
, vol.154
, pp. 5103-5113
-
-
Penit, C.1
Lucas, B.2
Vasseur, F.3
-
23
-
-
23844462453
-
Cutting edge: T cell development requires the combined activities of the p110γ and p110δ catalytic isoforms of phosphatidylinositol 3-kinase
-
Webb, L. M., E. Vigorito, M. P. Wymann, E. Hirsch, and M. Turner. 2005. Cutting edge: T cell development requires the combined activities of the p110γ and p110δ catalytic isoforms of phosphatidylinositol 3-kinase. J. Immunol. 175: 2783-2787.
-
(2005)
J. Immunol
, vol.175
, pp. 2783-2787
-
-
Webb, L.M.1
Vigorito, E.2
Wymann, M.P.3
Hirsch, E.4
Turner, M.5
-
24
-
-
0033386808
-
Caspase activation is required for T cell proliferation
-
Kennedy, N. J., T. Kataoka, J. Tschopp, and R. C. Budd. 1999. Caspase activation is required for T cell proliferation. J. Exp. Med. 190: 1891-1896.
-
(1999)
J. Exp. Med
, vol.190
, pp. 1891-1896
-
-
Kennedy, N.J.1
Kataoka, T.2
Tschopp, J.3
Budd, R.C.4
-
25
-
-
0037605790
-
Caspase activity is required for stimulated B lymphocytes to enter the cell cycle
-
Olson, N. E., J. D. Graves, G. L. Shu, E. J. Ryan, and E. A. Clark. 2003. Caspase activity is required for stimulated B lymphocytes to enter the cell cycle. J. Immunol. 170: 6065-6072.
-
(2003)
J. Immunol
, vol.170
, pp. 6065-6072
-
-
Olson, N.E.1
Graves, J.D.2
Shu, G.L.3
Ryan, E.J.4
Clark, E.A.5
-
26
-
-
4344560197
-
Caspase-8 serves both apoptotic and nonapoptotic roles
-
Kang, T. B., T. Ben-Moshe, E. E. Varfolomeev, Y. Pewzner-Jung, N. Yogev, A. Jurewicz, A. Waisman, O. Brenner, R. Haffner, E. Gustafsson, et al. 2004. Caspase-8 serves both apoptotic and nonapoptotic roles. J. Immunol. 173: 2976-2984.
-
(2004)
J. Immunol
, vol.173
, pp. 2976-2984
-
-
Kang, T.B.1
Ben-Moshe, T.2
Varfolomeev, E.E.3
Pewzner-Jung, Y.4
Yogev, N.5
Jurewicz, A.6
Waisman, A.7
Brenner, O.8
Haffner, R.9
Gustafsson, E.10
-
27
-
-
20044368218
-
The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival
-
Mandal, M., C. Borowski, T. Palomero, A. A. Ferrando, P. Oberdoerffer, F. Meng, A. Ruiz-Vela, M. Ciofani, J. C. Zuniga-Pflucker, I. Screpanti, et al. 2005. The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival. J. Exp. Med. 201: 603-614.
-
(2005)
J. Exp. Med
, vol.201
, pp. 603-614
-
-
Mandal, M.1
Borowski, C.2
Palomero, T.3
Ferrando, A.A.4
Oberdoerffer, P.5
Meng, F.6
Ruiz-Vela, A.7
Ciofani, M.8
Zuniga-Pflucker, J.C.9
Screpanti, I.10
-
28
-
-
33745200724
-
Overexpression of the antiapoptotic protein A1 promotes the survival of double positive thymocytes awaiting positive selection
-
Verschelde, C., D. Michonneau, M. C. Trescol-Biemont, I. Berberich, A. Schimpl, and N. Bonnefoy-Berard. 2006. Overexpression of the antiapoptotic protein A1 promotes the survival of double positive thymocytes awaiting positive selection. Cell Death Differ. 13: 1213-1221.
-
(2006)
Cell Death Differ
, vol.13
, pp. 1213-1221
-
-
Verschelde, C.1
Michonneau, D.2
Trescol-Biemont, M.C.3
Berberich, I.4
Schimpl, A.5
Bonnefoy-Berard, N.6
-
29
-
-
0030874326
-
The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression
-
von Freeden-Jeffry, U., N. Solvason, M. Howard, and R. Murray. 1997. The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression. Immunity 7: 147-154.
-
(1997)
Immunity
, vol.7
, pp. 147-154
-
-
von Freeden-Jeffry, U.1
Solvason, N.2
Howard, M.3
Murray, R.4
-
30
-
-
0042969051
-
Pre-TCR signaling regulates IL-7 receptor α expression promoting thymocyte survival at the transition from the double-negative to double-positive stage
-
Trigueros, C., K. Hozumi, B. Silva-Santos, L. Bruno, A. C. Hayday, M. J. Owen, and D. J. Pennington. 2003. Pre-TCR signaling regulates IL-7 receptor α expression promoting thymocyte survival at the transition from the double-negative to double-positive stage. Eur. J. Immunol. 33: 1968-1977.
-
(2003)
Eur. J. Immunol
, vol.33
, pp. 1968-1977
-
-
Trigueros, C.1
Hozumi, K.2
Silva-Santos, B.3
Bruno, L.4
Hayday, A.C.5
Owen, M.J.6
Pennington, D.J.7
-
31
-
-
1642321960
-
Thymocytes between the β-selection and positive selection checkpoints are nonresponsive to IL-7 as assessed by STAT-5 phosphorylation
-
Van De Wiele, C. J., J. H. Marino, B. W. Murray, S. S. Vo, M. E. Whetsell, and T. K. Teague. 2004. Thymocytes between the β-selection and positive selection checkpoints are nonresponsive to IL-7 as assessed by STAT-5 phosphorylation. J. Immunol. 172: 4235-4244.
-
(2004)
J. Immunol
, vol.172
, pp. 4235-4244
-
-
Van De Wiele, C.J.1
Marino, J.H.2
Murray, B.W.3
Vo, S.S.4
Whetsell, M.E.5
Teague, T.K.6
-
32
-
-
0035898387
-
Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid development
-
Lind, E. F., S. E. Prockop, H. E. Porritt, and H. T. Petrie. 2001. Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid development. J. Exp. Med. 194: 127-134.
-
(2001)
J. Exp. Med
, vol.194
, pp. 127-134
-
-
Lind, E.F.1
Prockop, S.E.2
Porritt, H.E.3
Petrie, H.T.4
-
33
-
-
33645099763
-
Thymic microenvironments for T cell differentiation and selection
-
Ladi, E., X. Yin, T. Chtanova, and E. A. Robey. 2006. Thymic microenvironments for T cell differentiation and selection. Nat. Immunol. 7: 338-343.
-
(2006)
Nat. Immunol
, vol.7
, pp. 338-343
-
-
Ladi, E.1
Yin, X.2
Chtanova, T.3
Robey, E.A.4
-
34
-
-
33644845679
-
Journey through the thymus: Stromal guides for T-cell development and selection
-
Takahama, Y. 2006. Journey through the thymus: stromal guides for T-cell development and selection. Nat. Rev. Immunol. 6: 127-135.
-
(2006)
Nat. Rev. Immunol
, vol.6
, pp. 127-135
-
-
Takahama, Y.1
-
35
-
-
33644637143
-
Thymocyte motility: Mutants, movies and migration patterns
-
Yin, X., T. Chtanova, E. Ladi, and E. A. Robey. 2006. Thymocyte motility: mutants, movies and migration patterns. Curr. Opin. Immunol. 18: 191-197.
-
(2006)
Curr. Opin. Immunol
, vol.18
, pp. 191-197
-
-
Yin, X.1
Chtanova, T.2
Ladi, E.3
Robey, E.A.4
-
36
-
-
10844231899
-
Ontogeny and regulation of IL-7-expressing thymic epithelial cells
-
Zamisch, M., B. Moore-Scott, D. M. Su, P. J. Lucas, N. Manley, and E. R. Richie. 2005. Ontogeny and regulation of IL-7-expressing thymic epithelial cells. J. Immunol. 174: 60-67.
-
(2005)
J. Immunol
, vol.174
, pp. 60-67
-
-
Zamisch, M.1
Moore-Scott, B.2
Su, D.M.3
Lucas, P.J.4
Manley, N.5
Richie, E.R.6
-
37
-
-
17444377206
-
The role of Notch and IL-7 signaling in early thymocyte proliferation and differentiation
-
Balciunaite, G., R. Ceredig, H. J. Fehling, J. C. Zuniga-Pflucker, and A. G. Rolink. 2005. The role of Notch and IL-7 signaling in early thymocyte proliferation and differentiation. Eur. J. Immunol. 35: 1292-1300.
-
(2005)
Eur. J. Immunol
, vol.35
, pp. 1292-1300
-
-
Balciunaite, G.1
Ceredig, R.2
Fehling, H.J.3
Zuniga-Pflucker, J.C.4
Rolink, A.G.5
|