-
1
-
-
0034523345
-
Phylogeny of the serpin superfamily: Implications of patterns of amino acid conservation for structure and function
-
Irving JA, Pike RN, Lesk AM, et al. Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function. Genome Res 2000; 10: 1845-1864.
-
(2000)
Genome Res
, vol.10
, pp. 1845-1864
-
-
Irving, J.A.1
Pike, R.N.2
Lesk, A.M.3
-
2
-
-
1642464622
-
Evolutionary families of peptidase inhibitors
-
Rawlings ND, Tolle DP, Barrett AJ. Evolutionary families of peptidase inhibitors. Biochem J 2004; 378: 705-716.
-
(2004)
Biochem J
, vol.378
, pp. 705-716
-
-
Rawlings, N.D.1
Tolle, D.P.2
Barrett, A.J.3
-
3
-
-
0035823595
-
The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature
-
Silverman GA, Bird PI, Carrell RW, et al. The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature. J Biol Chem 2001; 276: 33293-33296.
-
(2001)
J Biol Chem
, vol.276
, pp. 33293-33296
-
-
Silverman, G.A.1
Bird, P.I.2
Carrell, R.W.3
-
4
-
-
0034687422
-
Structure of a serpin-protease complex shows inhibition by deformation
-
Huntington JA, Read RJ, Carrell RW. Structure of a serpin-protease complex shows inhibition by deformation. Nature 2000; 407: 923-926.
-
(2000)
Nature
, vol.407
, pp. 923-926
-
-
Huntington, J.A.1
Read, R.J.2
Carrell, R.W.3
-
5
-
-
0037066736
-
Inhibitory activity of a heterochromatin-associated serpin (MENT) against papain-like cysteine proteinases affects chromatin structure and blocks cell proliferation
-
Irving JA, Shushanov SS, Pike RN, et al. Inhibitory activity of a heterochromatin-associated serpin (MENT) against papain-like cysteine proteinases affects chromatin structure and blocks cell proliferation. J Biol Chem 2002; 277: 13192-13201.
-
(2002)
J Biol Chem
, vol.277
, pp. 13192-13201
-
-
Irving, J.A.1
Shushanov, S.S.2
Pike, R.N.3
-
6
-
-
0345094925
-
A serpin regulates dorsal-ventral axis formation in the Drosophila embryo
-
Ligoxygakis P, Roth S, Reichhart JM. A serpin regulates dorsal-ventral axis formation in the Drosophila embryo. Curr Biol 2003; 13: 2097-2102.
-
(2003)
Curr Biol
, vol.13
, pp. 2097-2102
-
-
Ligoxygakis, P.1
Roth, S.2
Reichhart, J.M.3
-
7
-
-
2442485932
-
SRP-2 is a cross-class inhibitor that participates in postembryonic development of the nematode Caenorhabditis elegans: Initial characterization of the clade L serpins
-
Pak SC, Kumar V, Tsu C, et al. SRP-2 is a cross-class inhibitor that participates in postembryonic development of the nematode Caenorhabditis elegans: initial characterization of the clade L serpins. J Biol Chem 2004; 279: 15448-15459.
-
(2004)
J Biol Chem
, vol.279
, pp. 15448-15459
-
-
Pak, S.C.1
Kumar, V.2
Tsu, C.3
-
8
-
-
0033578917
-
Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila
-
Levashina EA, Langley E, Green C, et al. Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila. Science 1999; 285: 1917-1919.
-
(1999)
Science
, vol.285
, pp. 1917-1919
-
-
Levashina, E.A.1
Langley, E.2
Green, C.3
-
9
-
-
0026728952
-
Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme
-
Ray CA, Black RA, Kronheim SR, et al. Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme. Cell 1992; 69: 597-604.
-
(1992)
Cell
, vol.69
, pp. 597-604
-
-
Ray, C.A.1
Black, R.A.2
Kronheim, S.R.3
-
10
-
-
0038005314
-
Serpins: Structure, function and molecular evolution
-
Van Gent D, Sharp P, Morgan K, et al. Serpins: structure, function and molecular evolution. Int J Biochem Cell Biol 2003; 35: 1536-1547.
-
(2003)
Int J Biochem Cell Biol
, vol.35
, pp. 1536-1547
-
-
Van Gent, D.1
Sharp, P.2
Morgan, K.3
-
12
-
-
0036881507
-
Antithrombin deficiency: Issues in laboratory diagnosis
-
Kottke-Marchant K, Duncan A. Antithrombin deficiency: issues in laboratory diagnosis. Arch Pathol Lab Med 2002; 126: 1326-1336.
-
(2002)
Arch Pathol Lab Med
, vol.126
, pp. 1326-1336
-
-
Kottke-Marchant, K.1
Duncan, A.2
-
13
-
-
0032479424
-
Calcium enhances heparin catalysis of the antithrombin-factor Xa reaction by a template mechanism. Evidence that calcium alleviates Gla domain antagonism of heparin binding to factor Xa
-
Rezaie AR. Calcium enhances heparin catalysis of the antithrombin-factor Xa reaction by a template mechanism. Evidence that calcium alleviates Gla domain antagonism of heparin binding to factor Xa. J Biol Chem 1998; 273: 16924-16827.
-
(1998)
J Biol Chem
, vol.273
, pp. 16924-16827
-
-
Rezaie, A.R.1
-
14
-
-
0141609849
-
Mechanisms of glycosaminoglycan activation of the serpins in hemostasis
-
Huntington JA. Mechanisms of glycosaminoglycan activation of the serpins in hemostasis. J Thromb Haemost 2003; 1: 1535-1549.
-
(2003)
J Thromb Haemost
, vol.1
, pp. 1535-1549
-
-
Huntington, J.A.1
-
15
-
-
0033807066
-
Complete antithrombin deficiency in mice results in embryonic lethality
-
Ishiguro K, Kojima T, Kadomatsu K, et al. Complete antithrombin deficiency in mice results in embryonic lethality. J Clin Invest 2000; 106: 873-878.
-
(2000)
J Clin Invest
, vol.106
, pp. 873-878
-
-
Ishiguro, K.1
Kojima, T.2
Kadomatsu, K.3
-
16
-
-
26244432935
-
Control of the coagulation system by serpins. Getting by with a little help from glycosaminoglycans
-
Pike RN, Buckle AM, le Bonniec BF, et al. Control of the coagulation system by serpins. Getting by with a little help from glycosaminoglycans. FEBS J 2005; 272: 4842-4851.
-
(2005)
FEBS J
, vol.272
, pp. 4842-4851
-
-
Pike, R.N.1
Buckle, A.M.2
le Bonniec, B.F.3
-
17
-
-
0032483018
-
Isolation of a protein Z-dependent plasma protease inhibitor
-
Han X, Fiehler R, Broze GJ Jr. Isolation of a protein Z-dependent plasma protease inhibitor. Proc Natl Acad Sci U S A; 1998; 95: 9250-9255.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 9250-9255
-
-
Han, X.1
Fiehler, R.2
Broze Jr., G.J.3
-
18
-
-
0034329329
-
Characterization of the protein Z-dependent protease inhibitor
-
Han X, Fiehler R, Broze GJ Jr. Characterization of the protein Z-dependent protease inhibitor. Blood 2000; 96: 3049-3055.
-
(2000)
Blood
, vol.96
, pp. 3049-3055
-
-
Han, X.1
Fiehler, R.2
Broze Jr., G.J.3
-
19
-
-
26644467924
-
Down-regulation of factor IXa in the factor Xase complex by protein Z-dependent protease inhibitor
-
Heeb MJ, Cabral KM, Ruan, L. Down-regulation of factor IXa in the factor Xase complex by protein Z-dependent protease inhibitor. J Biol Chem 2005; 280: 33819-33825.
-
(2005)
J Biol Chem
, vol.280
, pp. 33819-33825
-
-
Heeb, M.J.1
Cabral, K.M.2
Ruan, L.3
-
20
-
-
0036880595
-
Heparin cofactor II deficiency
-
Tollefsen DM. Heparin cofactor II deficiency. Arch Pathol Lab Med 2002; 126: 1394-1400.
-
(2002)
Arch Pathol Lab Med
, vol.126
, pp. 1394-1400
-
-
Tollefsen, D.M.1
-
21
-
-
33745627306
-
A nonsense polymorphism in the protein Z-dependent protease inhibitor increases the risk for venous thrombosis
-
Corral J, Gonzalez-Conejero R, Soria JM, et al. A nonsense polymorphism in the protein Z-dependent protease inhibitor increases the risk for venous thrombosis. Blood 2006; 108: 177-183.
-
(2006)
Blood
, vol.108
, pp. 177-183
-
-
Corral, J.1
Gonzalez-Conejero, R.2
Soria, J.M.3
-
22
-
-
5644235083
-
Mutations within the protein Z-dependent protease inhibitor gene are associated with venous thromboembolic disease: A new form of thrombophilia
-
Water N, Tan T, Ashton F, et al. Mutations within the protein Z-dependent protease inhibitor gene are associated with venous thromboembolic disease: a new form of thrombophilia. Br J Haematol 2004; 127: 190-194.
-
(2004)
Br J Haematol
, vol.127
, pp. 190-194
-
-
Water, N.1
Tan, T.2
Ashton, F.3
-
23
-
-
0034923318
-
Protein Z-dependent regulation of coagulation
-
Broze GJ Jr. Protein Z-dependent regulation of coagulation. Thromb Haemost 2001; 86: 8-13.
-
(2001)
Thromb Haemost
, vol.86
, pp. 8-13
-
-
Broze Jr., G.J.1
-
24
-
-
33947532591
-
Protein Z/Z-dependent protease inhibitor (PZ/ZPI) anticoagulant system and thrombosis
-
Corral J, González-Conejero R, Hernández-Espinosa D, et al. Protein Z/Z-dependent protease inhibitor (PZ/ZPI) anticoagulant system and thrombosis. Br J Haematol 2007; 137: 99-108.
-
(2007)
Br J Haematol
, vol.137
, pp. 99-108
-
-
Corral, J.1
González-Conejero, R.2
Hernández-Espinosa, D.3
-
25
-
-
4444233600
-
Homozygous deficiency of heparin cofactor II: Relevance of P17 glutamate residue in serpins, relationship with conformational diseases, and role in thrombosis
-
Corral J, Aznar J, Gonzalez-Conejero R, et al. Homozygous deficiency of heparin cofactor II: relevance of P17 glutamate residue in serpins, relationship with conformational diseases, and role in thrombosis. Circulation 2004; 110: 1303-1307.
-
(2004)
Circulation
, vol.110
, pp. 1303-1307
-
-
Corral, J.1
Aznar, J.2
Gonzalez-Conejero, R.3
-
26
-
-
33646466168
-
Polymorphisms of the protein Z-dependent protease inhibitor (ZPI) gene and the risk of venous thromboembolism
-
Razzari C, Martinelli I, Bucciarelli P, et al. Polymorphisms of the protein Z-dependent protease inhibitor (ZPI) gene and the risk of venous thromboembolism. Thromb Haemost 2006; 95: 909-910.
-
(2006)
Thromb Haemost
, vol.95
, pp. 909-910
-
-
Razzari, C.1
Martinelli, I.2
Bucciarelli, P.3
-
29
-
-
0032589794
-
A 2.6 A structure of a serpin polymer and implications for conformational disease
-
Huntington JA, Pannu NS, Hazes B, et al. A 2.6 A structure of a serpin polymer and implications for conformational disease. J Mol Biol 1999; 293: 449-455.
-
(1999)
J Mol Biol
, vol.293
, pp. 449-455
-
-
Huntington, J.A.1
Pannu, N.S.2
Hazes, B.3
-
30
-
-
33747770769
-
Serpin crystal structure and serpin polymer structure
-
Marszal E, Shrake A. Serpin crystal structure and serpin polymer structure. Arch Biochem Biophys 2006; 453: 123-129.
-
(2006)
Arch Biochem Biophys
, vol.453
, pp. 123-129
-
-
Marszal, E.1
Shrake, A.2
-
31
-
-
0030841343
-
Conformational disease
-
Carrell RW, Lomas DA. Conformational disease. Lancet 1997; 350: 134-138.
-
(1997)
Lancet
, vol.350
, pp. 134-138
-
-
Carrell, R.W.1
Lomas, D.A.2
-
32
-
-
0036789017
-
Serpinopathies and the conformational dementias
-
Lomas DA, Carrell RW. Serpinopathies and the conformational dementias. Nat Rev Genet 2002; 3: 759-768.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 759-768
-
-
Lomas, D.A.1
Carrell, R.W.2
-
33
-
-
21744457450
-
Molecular mousetraps, alpha1-antitrypsin deficiency and the serpinopathies
-
Lomas DA. Molecular mousetraps, alpha1-antitrypsin deficiency and the serpinopathies. Clin Med 2005; 5: 249-257.
-
(2005)
Clin Med
, vol.5
, pp. 249-257
-
-
Lomas, D.A.1
-
34
-
-
0037011795
-
Alpha1-antitrypsin deficiency. A model for conformational diseases
-
Carrell RW, Lomas DA. Alpha1-antitrypsin deficiency. A model for conformational diseases. N Engl J Med 2002; 346: 45-53.
-
(2002)
N Engl J Med
, vol.346
, pp. 45-53
-
-
Carrell, R.W.1
Lomas, D.A.2
-
35
-
-
33645078896
-
Neuroserpin: A serpin to think about
-
Miranda E, Lomas DA. Neuroserpin: a serpin to think about. Cell Mol Life Sci 2006; 63: 709-722.
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 709-722
-
-
Miranda, E.1
Lomas, D.A.2
-
36
-
-
0032877043
-
Alpha 1-antitrypsin TAQ I polymorphism and alpha 1-antichymotrypsin mutations in patients with obstructive pulmonary disease
-
Benetazzo MG, Gile LS, Bombieri C, et al. Alpha 1-antitrypsin TAQ I polymorphism and alpha 1-antichymotrypsin mutations in patients with obstructive pulmonary disease. Respir Med 1999; 93: 648-654.
-
(1999)
Respir Med
, vol.93
, pp. 648-654
-
-
Benetazzo, M.G.1
Gile, L.S.2
Bombieri, C.3
-
37
-
-
0036212766
-
Current management of hereditary angio-oedema (C'1 esterase inhibitor deficiency)
-
Fay A, Abinun M. Current management of hereditary angio-oedema (C'1 esterase inhibitor deficiency). J Clin Pathol 2002; 55: 266-270.
-
(2002)
J Clin Pathol
, vol.55
, pp. 266-270
-
-
Fay, A.1
Abinun, M.2
-
40
-
-
0029589824
-
What do dysfunctional serpins tell us about molecular mobility and disease?
-
Stein PE, Carrell RW. What do dysfunctional serpins tell us about molecular mobility and disease? Nat Struct Biol 1995; 2: 96-113.
-
(1995)
Nat Struct Biol
, vol.2
, pp. 96-113
-
-
Stein, P.E.1
Carrell, R.W.2
-
41
-
-
0032559775
-
Trends in the incidence of deep vein thrombosis and pulmonary embolism: A 25-year population-based study
-
Silverstein MD, Heit JA, Mohr DN, et al. Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25-year population-based study. Arch Intern Med 1998; 158: 585-593.
-
(1998)
Arch Intern Med
, vol.158
, pp. 585-593
-
-
Silverstein, M.D.1
Heit, J.A.2
Mohr, D.N.3
-
42
-
-
0025942131
-
Physician practices in the prevention of venous thromboembolism
-
Amderson FA Jr, Wheeler HB, Goldberg RJ, et al. Physician practices in the prevention of venous thromboembolism. Ann Intern Med 1991; 115: 591-595.
-
(1991)
Ann Intern Med
, vol.115
, pp. 591-595
-
-
Amderson Jr, F.A.1
Wheeler, H.B.2
Goldberg, R.J.3
-
43
-
-
0026764834
-
A prospective study of the incidence of deep-vein thrombosis within a defined urban population
-
Nordstrom M, Lindblad B, Bergqvist D, et al. A prospective study of the incidence of deep-vein thrombosis within a defined urban population. J Intern Med 1992; 232: 155-160.
-
(1992)
J Intern Med
, vol.232
, pp. 155-160
-
-
Nordstrom, M.1
Lindblad, B.2
Bergqvist, D.3
-
44
-
-
0033535363
-
Predictors of survival after deep vein thrombosis and pulmonary embolism: A population-based, cohort study
-
Heit JA, Silverstein MD, Mohr DN, et al. Predictors of survival after deep vein thrombosis and pulmonary embolism: a population-based, cohort study. Arch Intern Med 1999; 159: 445-453.
-
(1999)
Arch Intern Med
, vol.159
, pp. 445-453
-
-
Heit, J.A.1
Silverstein, M.D.2
Mohr, D.N.3
-
45
-
-
0032558306
-
Science, medicine, and the future: Assessing thrombotic risk
-
Laffan M, Tuddenham E. Science, medicine, and the future: assessing thrombotic risk. Br Med J 1998; 317: 520-523.
-
(1998)
Br Med J
, vol.317
, pp. 520-523
-
-
Laffan, M.1
Tuddenham, E.2
-
46
-
-
84907041478
-
Thrombophilia caused by inheritable deficiency of blood antithrombin
-
Egeberg O. Thrombophilia caused by inheritable deficiency of blood antithrombin. Scand J Clin Lab Invest 1965; 17: 92.
-
(1965)
Scand J Clin Lab Invest
, vol.17
, pp. 92
-
-
Egeberg, O.1
-
47
-
-
34548666504
-
-
of London. Antithrombin mutation database. is/ haemo/coag/antithrombin
-
Bayston T, Lane D. Imperial College of London. Antithrombin mutation database. http://wwwfom.sk.med.ic.ac.uk/medicine/about/divisions/is/ haemo/coag/antithrombin.
-
Imperial College
-
-
Bayston, T.1
Lane, D.2
-
48
-
-
34548684898
-
-
OMIM
-
OMIM. http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=107300.
-
-
-
-
49
-
-
34548694194
-
-
HGMD
-
HGMD. http://www.hgmd.cf.ac.uk/ac/gene.php?gene=SERPINC1.
-
-
-
-
50
-
-
0035912152
-
Genetic susceptibility to venous thrombosis
-
Seligsohn U, Lubetsky A. Genetic susceptibility to venous thrombosis. N Engl J Med 2001; 344: 1222-1231.
-
(2001)
N Engl J Med
, vol.344
, pp. 1222-1231
-
-
Seligsohn, U.1
Lubetsky, A.2
-
51
-
-
0033600562
-
The protein Z-dependent protease inhibitor is a serpin
-
Han X, Huang ZF, Fiehler R, et al. The protein Z-dependent protease inhibitor is a serpin. Biochemistry 1999; 38: 11073-11078.
-
(1999)
Biochemistry
, vol.38
, pp. 11073-11078
-
-
Han, X.1
Huang, Z.F.2
Fiehler, R.3
-
52
-
-
0033570979
-
Formation of the antithrombin heterodimer in vivo and the onset of thrombosis
-
Zhou A, Huntington JA, Carrell RW. Formation of the antithrombin heterodimer in vivo and the onset of thrombosis. Blood 1999; 94: 3388-3396.
-
(1999)
Blood
, vol.94
, pp. 3388-3396
-
-
Zhou, A.1
Huntington, J.A.2
Carrell, R.W.3
-
53
-
-
0033578910
-
Antiangiogenic activity of the cleaved conformation of the serpin antithrombin
-
O'Reilly MS, Pirie-Shepherd S, Lane WS, et al. Antiangiogenic activity of the cleaved conformation of the serpin antithrombin. Science 1999; 285: 1926-1928.
-
(1999)
Science
, vol.285
, pp. 1926-1928
-
-
O'Reilly, M.S.1
Pirie-Shepherd, S.2
Lane, W.S.3
-
54
-
-
33846025442
-
Antiangiogenic antithrombin blocks the heparan sulfate-dependent binding of proangiogenic growth factors to their endothelial cell receptors
-
Zhang W, Swanson R, Xiong Y, et al. Antiangiogenic antithrombin blocks the heparan sulfate-dependent binding of proangiogenic growth factors to their endothelial cell receptors. J Biol Chem 2006; 281: 37302-37310.
-
(2006)
J Biol Chem
, vol.281
, pp. 37302-37310
-
-
Zhang, W.1
Swanson, R.2
Xiong, Y.3
-
55
-
-
13244295561
-
Mutations in the shutter region of antithrombin result in formation of disulfide-linked dimers and severe venous thrombosis
-
Corral J, Huntington JA, Gonzalez-Conejero R, et al. Mutations in the shutter region of antithrombin result in formation of disulfide-linked dimers and severe venous thrombosis. J Thromb Haemost 2004; 2: 931-939.
-
(2004)
J Thromb Haemost
, vol.2
, pp. 931-939
-
-
Corral, J.1
Huntington, J.A.2
Gonzalez-Conejero, R.3
-
56
-
-
0043245935
-
Antithrombin F229L: A new homozygous variant leading to spontaneous antithrombin polymerization in vivo associated with severe childhood thrombosis
-
Picard V, Dautzenberg MD, Villoutreix BO, et al. Antithrombin F229L: a new homozygous variant leading to spontaneous antithrombin polymerization in vivo associated with severe childhood thrombosis. Blood 2003; 102: 919-925.
-
(2003)
Blood
, vol.102
, pp. 919-925
-
-
Picard, V.1
Dautzenberg, M.D.2
Villoutreix, B.O.3
-
57
-
-
0027999955
-
Thromboembolic diseases due to conformational changes of antithrombin Rouen VI (187 Asnà Asp)
-
Bruce D, Perry DJ, Borg J-Y, et al. Thromboembolic diseases due to conformational changes of antithrombin Rouen VI (187 Asnà Asp). J Clin Invest 1994; 94: 2265-2274.
-
(1994)
J Clin Invest
, vol.94
, pp. 2265-2274
-
-
Bruce, D.1
Perry, D.J.2
Borg, J.-Y.3
-
58
-
-
0032532347
-
Antithrombins Wibble and Wobble (T85M/K): Archetypal conformational diseases with in vivo latent-transition, thrombosis, and heparin activation
-
Beauchamp NJ, Pike RN, Daly M, et al. Antithrombins Wibble and Wobble (T85M/K): archetypal conformational diseases with in vivo latent-transition, thrombosis, and heparin activation. Blood 1998; 92: 2696-2706.
-
(1998)
Blood
, vol.92
, pp. 2696-2706
-
-
Beauchamp, N.J.1
Pike, R.N.2
Daly, M.3
-
59
-
-
0035171975
-
Molecular mechanism of type I congenital heparin cofactor (HC) II deficiency caused by a missense mutation at reactive P2 site: HC II Tokushima
-
Kanagawa Y, Shigekiyo T, Aihara K, et al. Molecular mechanism of type I congenital heparin cofactor (HC) II deficiency caused by a missense mutation at reactive P2 site: HC II Tokushima. Thromb Haemost 2001; 85: 101-107.
-
(2001)
Thromb Haemost
, vol.85
, pp. 101-107
-
-
Kanagawa, Y.1
Shigekiyo, T.2
Aihara, K.3
-
60
-
-
0034768820
-
Creation of an additional glycosylation site as a mechanism for type I antithrombin deficiency
-
Fitches AC, Lewandowski K, Olds RJ. Creation of an additional glycosylation site as a mechanism for type I antithrombin deficiency. Thromb Haemost 2001; 86: 1023-1027.
-
(2001)
Thromb Haemost
, vol.86
, pp. 1023-1027
-
-
Fitches, A.C.1
Lewandowski, K.2
Olds, R.J.3
-
61
-
-
0031051903
-
Antithrombin Morioka (Cys 95-Arg): A novel missense mutation causing type I antithrombin deficiency
-
Ozawa T, Takikawa Y, Niiya K, et al. Antithrombin Morioka (Cys 95-Arg): a novel missense mutation causing type I antithrombin deficiency. Thromb Haemost 1997; 77: 403.
-
(1997)
Thromb Haemost
, vol.77
, pp. 403
-
-
Ozawa, T.1
Takikawa, Y.2
Niiya, K.3
-
62
-
-
0028170632
-
Three novel mutations of antithrombin inducing high-molecular-mass compounds
-
Emmerich J, Vidaud D, Alhenc-Gelas M, et al. Three novel mutations of antithrombin inducing high-molecular-mass compounds. Arterioscler Thromb 1994; 14: 1958-1965.
-
(1994)
Arterioscler Thromb
, vol.14
, pp. 1958-1965
-
-
Emmerich, J.1
Vidaud, D.2
Alhenc-Gelas, M.3
-
63
-
-
12344264070
-
Conformational Asn187Asp/Lys antithrombin variants and thrombosis. Clinical and biological features in 13 new heterozygotes
-
Picard V, Bauters A, Khairy M, et al. Conformational Asn187Asp/Lys antithrombin variants and thrombosis. Clinical and biological features in 13 new heterozygotes. Thromb Haemost 2005; 93: 57-62.
-
(2005)
Thromb Haemost
, vol.93
, pp. 57-62
-
-
Picard, V.1
Bauters, A.2
Khairy, M.3
-
64
-
-
0028915906
-
Antithrombin-TRI (Ala382 to Thr) causing severe thromboembolic tendency undergoes the S-to-R transition and is associated with a plasma-inactive high-molecular-weight complex of aggregated antithrombin
-
Lindo VS, Kakkar W, Learmonth M, et al. Antithrombin-TRI (Ala382 to Thr) causing severe thromboembolic tendency undergoes the S-to-R transition and is associated with a plasma-inactive high-molecular-weight complex of aggregated antithrombin. Br J Haematol 1995; 89: 589-601.
-
(1995)
Br J Haematol
, vol.89
, pp. 589-601
-
-
Lindo, V.S.1
Kakkar, W.2
Learmonth, M.3
-
65
-
-
0029816014
-
Exhaustive mutation scanning by fluorescence-assisted mismatch analysis discloses new genotype-phenotype correlations in angioedema
-
Verpy E, Biasotto M, Brai M, et al. Exhaustive mutation scanning by fluorescence-assisted mismatch analysis discloses new genotype-phenotype correlations in angioedema. Am J Hum Genet 1996; 59: 308-319.
-
(1996)
Am J Hum Genet
, vol.59
, pp. 308-319
-
-
Verpy, E.1
Biasotto, M.2
Brai, M.3
-
66
-
-
17444434242
-
C1 inhibitor hinge region mutations produce dysfunction by different mechanisms
-
Davis AE, Aulak K, Parad RB, et al. C1 inhibitor hinge region mutations produce dysfunction by different mechanisms. Nature Genet 1992; 1: 354-358.
-
(1992)
Nature Genet
, vol.1
, pp. 354-358
-
-
Davis, A.E.1
Aulak, K.2
Parad, R.B.3
-
67
-
-
0024582992
-
CpG mutations in the reactive site of human C1 inhibitor
-
Skriver K, Radziejewska E, Siebermann JA, et al. CpG mutations in the reactive site of human C1 inhibitor. J Bio Chem 1989; 264: 3066-3071.
-
(1989)
J Bio Chem
, vol.264
, pp. 3066-3071
-
-
Skriver, K.1
Radziejewska, E.2
Siebermann, J.A.3
-
68
-
-
0026540117
-
Type II hereditary angio-oedema associated with two mutations in one allele of the C1-inhibitor gene around the reactive-site coding region
-
Siddique Z, McPhaden AR, Whaley K. Type II hereditary angio-oedema associated with two mutations in one allele of the C1-inhibitor gene around the reactive-site coding region. Hum Hered 1992; 42: 298-301.
-
(1992)
Hum Hered
, vol.42
, pp. 298-301
-
-
Siddique, Z.1
McPhaden, A.R.2
Whaley, K.3
-
69
-
-
0025097925
-
Type II hereditary angioneurotic edema that may result from a single nucleotide change in the codon for alanine-436 in the C1 inhibitor gene
-
Levy NJ, Ramesh N, Cicardi M, et al. Type II hereditary angioneurotic edema that may result from a single nucleotide change in the codon for alanine-436 in the C1 inhibitor gene. Proc Nat Acad Sci 1990; 87: 265-268.
-
(1990)
Proc Nat Acad Sci
, vol.87
, pp. 265-268
-
-
Levy, N.J.1
Ramesh, N.2
Cicardi, M.3
-
70
-
-
0028804702
-
Crucial residues in the carboxy-terminal end of C1 inhibitor revealed by pathogenic mutants impaired in secretion or function
-
Verpy E, Couture-Tosi E, Eldering E, et al. Crucial residues in the carboxy-terminal end of C1 inhibitor revealed by pathogenic mutants impaired in secretion or function. J Clin Invest 1995; 95: 350-359.
-
(1995)
J Clin Invest
, vol.95
, pp. 350-359
-
-
Verpy, E.1
Couture-Tosi, E.2
Eldering, E.3
-
71
-
-
4444275023
-
Mutation screening of the C1 inhibitor gene among Hungarian patients with hereditary angioedema
-
Kalmar L, Bors A, Farkas H, et al. Mutation screening of the C1 inhibitor gene among Hungarian patients with hereditary angioedema. Hum Mutat 2003; 22: 498.
-
(2003)
Hum Mutat
, vol.22
, pp. 498
-
-
Kalmar, L.1
Bors, A.2
Farkas, H.3
-
72
-
-
0024423930
-
Implications of the three-dimensional structure of alpha 1-antitrypsin for structure and function of serpins
-
Huber R, Carrell RW. Implications of the three-dimensional structure of alpha 1-antitrypsin for structure and function of serpins. Biochemistry 1989; 28: 8951-8966.
-
(1989)
Biochemistry
, vol.28
, pp. 8951-8966
-
-
Huber, R.1
Carrell, R.W.2
-
73
-
-
0024416244
-
Hereditary alpha 2-plasmin inhibitor deficiency caused by a transport-deficient mutation (alpha 2-PI-Okinawa). Deletion of Glu137 by a trinucleotide deletion blocks intracellular transport
-
Miura O, Sugahara Y, Aoki N. Hereditary alpha 2-plasmin inhibitor deficiency caused by a transport-deficient mutation (alpha 2-PI-Okinawa). Deletion of Glu137 by a trinucleotide deletion blocks intracellular transport. J Biol Chem 1989; 264: 18213-18219.
-
(1989)
J Biol Chem
, vol.264
, pp. 18213-18219
-
-
Miura, O.1
Sugahara, Y.2
Aoki, N.3
-
75
-
-
0035952980
-
Conformational properties of serine proteinase inhibitors (serpins) confer multiple pathophysiological roles
-
Janciauskiene S. Conformational properties of serine proteinase inhibitors (serpins) confer multiple pathophysiological roles. Biochim Biophys Acta 2001; 1535: 221-235.
-
(2001)
Biochim Biophys Acta
, vol.1535
, pp. 221-235
-
-
Janciauskiene, S.1
-
76
-
-
13244269951
-
Latent antithrombin and its detection, formation and turnover in the circulation
-
Mushunje A, Evans G, Brennan SO, et al. Latent antithrombin and its detection, formation and turnover in the circulation. J Thromb Haemost 2004; 2: 2170-2177.
-
(2004)
J Thromb Haemost
, vol.2
, pp. 2170-2177
-
-
Mushunje, A.1
Evans, G.2
Brennan, S.O.3
-
77
-
-
0345255812
-
Detection of conformational transformation of antithrombin in blood by crossed immunoelectrophoresis: New application for a classical method. Effect of temperature in plasmatic antithrombin; role in senescence of antithrombin and thrombosis
-
Corral J, Rivera J, Martínez C, et al. Detection of conformational transformation of antithrombin in blood by crossed immunoelectrophoresis: New application for a classical method. Effect of temperature in plasmatic antithrombin; role in senescence of antithrombin and thrombosis. J Lab Clin Med 2003; 142: 298-315.
-
(2003)
J Lab Clin Med
, vol.142
, pp. 298-315
-
-
Corral, J.1
Rivera, J.2
Martínez, C.3
-
78
-
-
0034737309
-
Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation
-
Nar H, Bauer M, Stassen JM, et al. Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation. J Mol Biol 2000; 297: 683-695.
-
(2000)
J Mol Biol
, vol.297
, pp. 683-695
-
-
Nar, H.1
Bauer, M.2
Stassen, J.M.3
-
79
-
-
0038053035
-
Serpin polymerization is prevented by a hydrogen bond network that is centered on his-334 and stabilized by glycerol
-
Zhou A, Stein PE, Huntington JA, et al. Serpin polymerization is prevented by a hydrogen bond network that is centered on his-334 and stabilized by glycerol. J Biol Chem 2003; 278: 15116-15122.
-
(2003)
J Biol Chem
, vol.278
, pp. 15116-15122
-
-
Zhou, A.1
Stein, P.E.2
Huntington, J.A.3
-
80
-
-
30644472060
-
The risk of thrombosis in patients with acute leukemia: Occurrence of thrombosis at diagnosis and during treatment
-
De Stefano V, Sora F, Rossi E, et al. The risk of thrombosis in patients with acute leukemia: occurrence of thrombosis at diagnosis and during treatment. J Thromb Haemost 2005; 3: 1985-1992.
-
(2005)
J Thromb Haemost
, vol.3
, pp. 1985-1992
-
-
De Stefano, V.1
Sora, F.2
Rossi, E.3
-
81
-
-
33745714798
-
L-asparaginase-induced antithrombin type I deficiency: Implications for conformational diseases
-
Hernandez-Espinosa D, Minano A, Martinez C, et al. L-asparaginase-induced antithrombin type I deficiency: implications for conformational diseases. Am J Pathol 2006: 169: 142-153.
-
(2006)
Am J Pathol
, vol.169
, pp. 142-153
-
-
Hernandez-Espinosa, D.1
Minano, A.2
Martinez, C.3
-
82
-
-
0026581553
-
Protein C in patients with alcoholic cirrhosis and other liver diseases
-
Bell H, Odegaard OR, Andersson T, et al. Protein C in patients with alcoholic cirrhosis and other liver diseases. J Hepatol 1992; 14: 163-167.
-
(1992)
J Hepatol
, vol.14
, pp. 163-167
-
-
Bell, H.1
Odegaard, O.R.2
Andersson, T.3
-
83
-
-
0030043815
-
Disseminated intravascular coagulation and antithrombin III depression in acute fatty liver of pregnancy
-
Castro MA, Goodwin TM, Shaw KJ, et al. Disseminated intravascular coagulation and antithrombin III depression in acute fatty liver of pregnancy. Am J Obstet Gynecol 1996; 174: 211-216.
-
(1996)
Am J Obstet Gynecol
, vol.174
, pp. 211-216
-
-
Castro, M.A.1
Goodwin, T.M.2
Shaw, K.J.3
-
84
-
-
33745603440
-
Intracellular retention of hepatic serpins caused by severe hyperlipidemia
-
Hernandez-Espinosa D, Ayala I, Castells MT, et al. Intracellular retention of hepatic serpins caused by severe hyperlipidemia. Liver Int 2006; 26: 708-715.
-
(2006)
Liver Int
, vol.26
, pp. 708-715
-
-
Hernandez-Espinosa, D.1
Ayala, I.2
Castells, M.T.3
-
85
-
-
34247871526
-
In vivo effects of hyperthermia on the functional and conformational characteristics of antithrombin
-
Hernandez-Espinosa D, Mota R, Miñano A, et al. In vivo effects of hyperthermia on the functional and conformational characteristics of antithrombin. J Thromb Haemost 2007; 5: 963-970.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 963-970
-
-
Hernandez-Espinosa, D.1
Mota, R.2
Miñano, A.3
|