Eosinophils from lineage-ablated ΔdblGATA bone marrow progenitors: The dblGATA enhancer in the promoter of GATA-1 is not essential for differentiation ex vivo

Journal of Immunology

Volumn 179, Issue 3, 2007, Pages 1693-1699

  Dyer, Kimberly D ^a   Czapiga, Meggan ^a   Foster, Barbara ^a   Foster, Paul S ^b   Kang, Elizabeth M ^a   Lappas, Courtney M ^a   Moser, Jennifer M ^a   Naumann, Nora ^a   Percopo, Caroline M ^a   Siegel, Steven J ^a   Swartz, Jonathan M ^a   Ravin, Suksee Ting De ^a   Rosenberg, Helene F ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

EOSINOPHIL PEROXIDASE; MAJOR BASIC PROTEIN; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR GATA 3; GATA1 PROTEIN, MOUSE; GATA2 PROTEIN, MOUSE; GATA3 PROTEIN, MOUSE; INTERLEUKIN 5; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL GRANULE; CELL GROWTH; CELL LINEAGE; CELL MATURATION; CONTROLLED STUDY; EOSINOPHIL; EX VIVO STUDY; FIBROBLAST; IMMUNOCOMPETENT CELL; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SEQUENCE ANALYSIS; STROMA CELL; ANIMAL; BAGG ALBINO MOUSE; BINDING SITE; BONE MARROW CELL; CELL CULTURE; CELL PROLIFERATION; COCULTURE; CYTOLOGY; ENHANCER REGION; GENETICS; HEMATOPOIETIC STEM CELL; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; PROMOTER REGION; TH2 CELL; TRANSPLANTATION;

ANIMALS; BINDING SITES; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CELLS, CULTURED; COCULTURE TECHNIQUES; ENHANCER ELEMENTS (GENETICS); EOSINOPHILS; GATA1 TRANSCRIPTION FACTOR; GATA2 TRANSCRIPTION FACTOR; GATA3 TRANSCRIPTION FACTOR; HEMATOPOIETIC STEM CELLS; INTERLEUKIN-5; MALE; MICE; MICE, INBRED BALB C; MICE, MUTANT STRAINS; PROMOTER REGIONS (GENETICS); TH2 CELLS;

EID: 34548654413     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.179.3.1693     Document Type: Article

References (30)

1. Humbles, A. A., C. M. Lloyd, S. J. McMillan, D. S. Friend, G. Xanthou, E. E. McKenna, S. Ghiran, N. P. Gerard, C. Yu, S. H. Orkin, and C. Gerard. 2004. A critical role for eosinophils in allergic airways remodeling. Science 305: 1776-1779.
2. Lee, J. J., D. Dimina, M. P. Macias, S. I. Ochkur, M. P. McGarry, K. R. O'Neill, C. Protheroe, R. Pero, T. Nguyen, S. A. Cormier, et al. 2004. Defining a link with asthma in mice congenitally deficient in eosinophils. Science 305: 1773-1776.
3. Swartz, J. M., K. D. Dyer, A. W. Cheever, T. Ramalingam, L. Pesnicak, J. B. Domachowske, J. J. Lee, N. A. Lee, P. S. Foster, T. A. Wynn, and H. F. Rosenberg. 2006. Schistosoma mansoni infection in eosinophil lineage-ablated mice. Blood 108: 2420-2427.
4. Yu, C., A. B. Cantor, H. Yang, C. Browne, R. A. Wells, Y. Fujiwara, and S. H. Orkin. 2002. Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo. J. Exp. Med. 195: 1387-1395.
5. Fujiwara, Y., C. P. Browne, K. Cunniff, S. C. Goff, and S. H. Orkin. 1996. Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1. Proc. Natl. Acad. Sci. USA 93: 12355-12358.
6. Pevny, L., M. C. Simon, E. Robertson, W. H. Klein, S. F. Tsai, V. D'Agati, S. H. Orkin, and F. Costantini. 1991. Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1. Nature 349: 257-260.
7. Fulkerson, P. C., C. A. Fischetti, M. L. McBride, L. M. Hassman, S. P. Hogan, and M. E. Rothenberg. 2006. A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammation. Proc. Natl. Acad. Sci. USA 103: 16418-16423.
8. Bystrom, J., K. D. Dyer, S. S. Ting-De Ravin, N. Naumann, D. A. Stephany, P. S. Foster, T. A. Wynn, and H. F. Rosenberg. 2006. Interleukin-5 does not influence differential transcription of transmembrane and soluble isoforms of IL-5R α in vivo. Eur. J. Haematol. 77: 181-190.
9. Domachowske, J. B., C. A. Bonville, A. J. Easton, and H. F. Rosenberg. 2002. Differential expression of proinflammatory cytokine genes in vivo in response to pathogenic and nonpathogenic pneumovirus infections. J. Infect. Dis. 186: 8-14.
10. Nitto, T., K. D. Dyer, M. Czapiga, and H. F. Rosenberg. 2006. Evolution and function of leukocyte RNase A ribonucleases of the avian species, Gallus gallus. J. Biol. Chem. 281: 25622-25634.
11. Grimaldi, J. C., N. X. Yu, G. Grunig, B. W. Seymour, F. Cottrez, D. S. Robinson, N. Hosken, W. G. Ferlin, X. Wu, H. Soto, et al. 1999. Depletion of eosinophils in mice through the use of antibodies specific for C-C chemokine receptor 3 (CCR3). J. Leukocyte Biol. 65: 846-853.
12. Tateno, H., P. R. Crocker, and J. C. Paulson. 2005. Mouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6′-sulfo-sialyl Lewis X as a preferred glycan ligand. Glycobiology 15: 1125-1135.
13. Zhang, J. Q., B. Biedermann, L. Nitschke, and P. R. Crocker. 2004. The murine inhibitory receptor mSiglec-E is expressed broadly on cells of the innate immune system whereas mSiglec-F is restricted to eosinophils. Eur. J. Immunol. 34: 1175-1184.
14. Her, E., J. Frazer, K. F. Austen, and W. F. Owen, Jr. 1991. Eosinophil hematopoietins antagonize the programmed cell death of eosinophils: cytokine and glucocorticoid effects on eosinophils maintained by endothelial cell-conditioned medium. J. Clin. Invest. 88: 1982-1987.
15. Stern, M., L. Meagher, J. Savill, and C. Haslett. 1992. Apoptosis in human eosinophils: programmed cell death in the eosinophil leads to phagocytosis by macrophages and is modulated by IL-5. J. Immunol. 148: 3543-3549.
16. Yamaguchi, Y., T. Suda, S. Ohta, K. Tominaga, Y. Miura, and T. Kasahara. 1991. Analysis of the survival of mature human eosinophils: interleukin-5 prevents apoptosis in mature human eosinophils. Blood 78: 2542-2547.
17. Ito, E., T. Toki, H. Ishihara, H. Ohtani, L. Gu, M. Yokoyama, J. D. Engel, and M. Yamamoto. 1993. Erythroid transcription factor GATA-1 is abundantly transcribed in mouse testis. Nature 362: 466-468.
18. Nicolis, S., C. Bertini, A. Ronchi, S. Crotta, L. Lanfranco, E. Moroni, B. Giglioni, and S. Ottolenghi. 1991. An erythroid specific enhancer upstream to the gene encoding the cell-type specific transcription factor GATA-1. Nucleic Acids Res. 19: 5285-5291.
19. Tsai, S. F., E. Strauss, and S. H. Orkin. 1991. Functional analysis and in vivo footprinting implicate the erythroid transcription factor GATA-1 as a positive regulator of its own promoter. Genes Dev. 5: 919-931.
20. Seshasayee, D., J. N. Geiger, P. Gaines, and D. M. Wojchowski. 2000. Intron 1 elements promote erythroid-specific GATA-1 gene expression. J. Biol. Chem. 275: 22969-22977.
21. Rothenberg, M. E., and S. P. Hogan. 2006. The eosinophil. Annu. Rev. Immunol. 24: 147-174.
22. Dyer, K. D., and H. F. Rosenberg. 2000. Shared features of transcription: mutational analysis of the eosinophil/basophil Charcot-Leyden crystal protein gene promoter. J. Leukocyte Biol. 67: 691-698.
23. Gombart, A. F., S. H. Kwok, K. L. Anderson, Y. Yamaguchi, B. E. Torbett, and H. P. Koeffler. 2003. Regulation of neutrophil and eosinophil secondary granule gene expression by transcription factors C/EBP ε and PU. 1. Blood 101: 3265-3273.
24. Handen, J. S., and H. F. Rosenberg. 1997. Intronic enhancer activity of the eosinophil-derived neurotoxin (RNS2) and eosinophil cationic protein (RNS3) genes is mediated by an NFAT-1 consensus binding sequence. J. Biol. Chem. 272: 1665-1669.
25. Yamaguchi, Y., S. J. Ackerman, N. Minegishi, M. Takiguchi, M. Yamamoto, and T. Suda. 1998. Mechanisms of transcription in eosinophils: GATA-1, but not GATA-2, transactivates the promoter of the eosinophil granule major basic protein gene. Blood 91: 3447-3458.
26. Ohneda, K., R. Shimizu, S. Nishimura, Y. Muraosa, S. Takahashi, J. D. Engel, and M. Yamamoto. 2002. A minigene containing four discrete cis elements recapitulates GATA-1 gene expression in vivo. Genes Cells 7: 1243-1254.
27. Trainor, C. D., J. G. Omichinski, T. L. Vandergon, A. M. Gronenborn, G. M. Clore, and G. Felsenfeld. 1996. A palindromic regulatory site within vertebrate GATA-1 promoters requires both zinc fingers of the GATA-1 DNA-binding domain for high-affinity interaction. Mol. Cell Biol. 16: 2238-2247.
28. Kitamura, Y., and S. Go. 1979. Decreased production of mast cells in S1/S1d anemic mice. Blood 53: 492-497.
29. Morii, E., K. Oboki, K. Ishihara, T. Jippo, T. Hirano, and Y. Kitamura. 2004. Roles of MITF for development of mast cells in mice: effects on both precursors and tissue environments. Blood 104: 1656-1661.
30. Swartz, J. M., J. Bystrom, K. D. Dyer, T. Nitto, T. A. Wynn, and H. F. Rosenberg. 2004. Plasminogen activator inhibitor-2 (PAI-2) in eosinophilic leukocytes. J. Leukocyte Biol. 76: 812-819.