Role of inositol 1,4,5-trisphosphate receptors in regulating apoptotic signaling and heart failure

Heart and Vessels

Volumn 12, Issue SUPPL. 12, 1997, Pages 53-57

  Gutstein, David E ^a   Marks, Andrew R ^a  

^a Columbia University ^*  (United States)

Author keywords

Calcium; Cell death; Channel; Contraction coupling; Excitation; Ryanodine receptor

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM; DEXAMETHASONE; FAS ANTIGEN; INOSITOL 1,4,5 TRISPHOSPHATE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; RYANODINE RECEPTOR; T LYMPHOCYTE RECEPTOR; CALCIUM CHANNEL; CELL RECEPTOR; DNA; ITPR1 PROTEIN, HUMAN; ITPR2 PROTEIN, HUMAN; MESSENGER RNA;

APOPTOSIS; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CELL SURVIVAL; CONFERENCE PAPER; DOWN REGULATION; EXCITATION CONTRACTION COUPLING; HEART FAILURE; HEART MUSCLE CELL; HUMAN; IONIZING RADIATION; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SARCOPLASMIC RETICULUM; T LYMPHOCYTE; ARTICLE; CYTOLOGY; GENETICS; HEART DISEASE; HEART MUSCLE; IMMUNOHISTOCHEMISTRY; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; UPREGULATION;

APOPTOSIS; CALCIUM; CALCIUM CHANNELS; DNA; HEART DISEASES; HUMANS; IMMUNOHISTOCHEMISTRY; INOSITOL 1,4,5-TRISPHOSPHATE; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; MYOCARDIUM; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 0031283329     PISSN: 09108327     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (50)

1. Marks AR (1997) Intracellular calcium release channels: regulators of cell life and death. Am J Phys 41:H597-H605
2. Berridge MJ (1993) Inositol trisphosphate and calcium signaling. Nature 361:315-325
3. Harnick DH, Jayaraman T, Go L, Ma Y, Mulieri P, Marks AR (1995) The human type 1 inositol 1,4,5-trisphosphate receptor from T lymphocytes: structure, localization and phosphorylation. J Biol Chem 270:2833-2840
4. Moschella MC, Marks AR (1993) Inositol 1,4,5-trisphosphate receptor expression in cardiac myocytes. J Cell Biol 120:1137-1146
5. Moschella MC, Jayaraman T, Watras J, Marks AR (1995) Inositol 1,4,5-trisphosphate receptor in skeletal muscle: differential expression in myofibres. J Cell Motil Muscle Res 16:390-400
6. Fleischer S, Inui M (1989) Biochemistry and biophysics of excitation-contraction coupling. Annu Rev Biophys Biophys Chem 18:333-364
7. Callewaert G (1992) Excitation-contraction coupling in mammalian cardiac cells. Cardiovasc Res 26:923-932
8. Barry WH, Bridge JH (1993) Intracellular calcium homeostasis in cardiac myocytes (review). Circulation 87:1806-1815
9. Sanderson MJ, Charles AC, Boitano S, Dirksen ER (1994) Mechanisms and function of intercellular calcium signaling. Mol Cell Endocrinol 98:173-187
10. Cockcroft S, Thomas GMH (1992) Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors. Biochem J 288:1-14
11. Ferris CD, Snyder SH (1992) Inositol 1,4,5-trisphosphate-activated calcium channels. Annu Rev Physiol 54:469-488
12. Jayaraman T, Ondrias K, Ondriasova E, Marks AR (1996) Regulation of the inositol 1,4,5-trisphosphate receptor by tyrosine phosphorylation. Science 272:1492-1494
13. Furuichi T, Yoshikawa S, Miyawaki A, Wada K, Maeda N, Mikoshiba K (1989) Primary structue and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400. Nature 342:32-38
14. Mignery GA, Newton CL, Archer BT, Sudhof TC (1990) Structure and expression of the rat inositol-1,4,5-trisphosphate receptor. J Biol Chem 265:12679-12685
15. Kume S, Muto A, Aruga J, et al (1993) The Xenopus oocyte IP3 receptor: structure, function and localization in oocytes. Cell 73:555-570
16. Chadwick CC, Saito A, Fleischer S (1990) Isolation and characterization of the inositol trisphosphate receptor from smooth muscle. Proc Natl Acad Sci 87:2132-2136
17. Ferris CD, Huganir RL, Supattapone S, Snyder SH (1989) Purified inositol 1,4,5-trisphosphate receptor mediates calcium flux in reconstituted lipid vesicles. Nature 342:87-89
18. Mourey RJ, Verma A, Supattapone S, Snyder SH (1990) Purification and characterization of the inositol 1,4,5-trisphosphate receptor protein from rat vas deferens. Biochem J 272:383-389
19. Ross CA, Meldolesi J, Milner TA, Saloh T, Supattapone S, Snyder SH (1989) Inositol 1,4,5-trisphosphate receptor localized to endoplasmic reticulum in cerebellar Purkinje neurons. Nature 339:468-470
20. Wojcikiewicz RJH (1995) Type I, II, and III inositol 1,4,5-trisphosphate receptors are equally susceptible to down-regulation and are expressed in markedly different proportions in different cell types. J Biol Chem 270:11678-11683
21. Gorza L, Schiaffino S, Volpe P (1993) Inositol 1,4,5-trisphosphate receptor in heart: evidence for its concentration in Purkinje myocytes of the conduction system. J Cell Biol 121:345-353
22. Kijima Y, Saito A, Jetton TL, Magnuson MA, Fleischer S (1993) Different intracellular localization of inositol 1,4,5-trisphosphate and ryandoine receptors in cardiomyocytes. J Biol Chem 268:3499-3506
23. Kentish J, Barsotti R, Lea T, Mulligan I, Patel J, Ferenczi M (1990) Calcium release from cardiac sarcoplasmic reticulum induced by photorelease of calcium or Ins (1,4,5)P3. Am J Physiol 258:H610-H615
24. Beuckelmann DJ, Nabauer M, Erdmann E (1992) Intracellular calcium handling in isolated ventricular myocytes from patients with terminal heart failure. Circulation 85:1046-1055
25. Gwathmey JK, Copelas L, Mackinnon R, et al (1987) Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failure. Circ Res 61:70-76
26. Brillantes AM, Allen PD, Takahasi T, Izumo S, Marks AR (1992) Differences in cardiac calcium release channel (ryanodine receptor) expression in myocardium from patients with end-stage heart failure caused by ischemic versus dilated cardiomyopathy. Circ Res 71:18-26
27. Go LO, Moschella MC, Watras J, Handa KK, Fyfe BS, Marks AR (1995) Differential regulation of two types of intracellular calcium release channels during end-stage heart failure. J Clin Invest 95:888-894
28. Arai M, Alpert NR, MacLennan DH, Barton P, Periasamy M (1993) Alterations in sarcoplasmic reticulum gene expression in human heart failure: a possible mechanism for alterations in systolic and diastolic properties of the failing myocardium. Circ Res 72:463-469
29. Dodd DA, Atkinson JB, Olson RD, et al (1993) Doxorubicin cardiomyopathy is associated with a decrease in calcium release channel of the sarcoplasmic reticulum in a chronic rabbit model. J Clin Invest 91:1697-1705
30. Matsui H, MacLennan DH, Alpert NR, Periasamy M (1995) Sarcoplasmic reticulum gene expression in pressure overload-induced cardiac hypertrophy in rabbit. Am J Physiol 268:C252-258
31. Vatner DE, Sato N, Kiuchi K, Shannon RP, Vatner SF (1994) Decrease in myocardial ryanodine receptors and altered excitation-contraction coupling early in the development of heart failure. Circulation 90:1423-1430
32. Cory RC, McCutcheon LJ, O'Grady M, Pang AW, Geiger JO, O'Brien PJ (1993) Compensatory downregulation of myocardial Ca channel in SR from dogs with heart failure. Am J Physiol 264:H926-H927
33. Handa KK, Moschella MC, Fyfe B, Marks AR (1993) Regulation of calcium channel expression during heart failure. Circulation 88(suppl I):624
34. Kapelko VI, Williams CP, Gutstein DE, Morgan JP (1996) Abnormal myocardial calcium handling in the early stage of adriamycin cardiomyopathy. Arch Physiol Biochem 104:185-191
35. Olivetti G, Abbi R, Quaini F, et al (1997) Apoptosis in the failing human heart. N Engl J Med 336:1131-1141
36. Narula J, Haider N, Virmani R, et al (1996) Apoptosis in myocytes in end-stage heart failure. N Engl J Med 335:1182-1189
37. Mallat Z, Tedgui A, Fontaliran F, Frank R, Durigon M, Fontaine G (1996) Evidence of apoptosis in arrhythmogenic right ventricular dysplasia. N Engl J Med 335:1190-1196
38. Saraste A, Pulkki K, Kallajoki M, Henriksen K, Parvinen M, Voipio-Pulkki L-M (1997) Apoptosis in human acute myocardial infarction. Circulation 95:320-323
39. James TN, St. Martin E, Willis PW, Lohr TO (1996) Apoptosis as a possible cause of gradual development of complete heart block and fatal arrhythmias associated with absence of the AV node, sinus node, and internodal pathways. Circulation 93:1424-1438
40. Sharov VG, Sabbah HN, Shimoyama H, Goussev AV, Lesch M, Goldstein S (1996) Evidence of cardiocyte apoptosis in myocardium of dogs with chronic heart failure. Am J Pathol 148:141-149
41. Liu Y, Cigola E, Cheng W, et al (1995) Myocyte nucler mitotic division and programmed myocyte cell death characterize the cardiac myopathy induced by rapid ventricular pacing in dogs. Lab Invest 73:771-787
42. Bialik S, Geenen DL, Sasson I, et al (1997) Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53. J Clin Invest (in press)
43. Kajstura J, Cheng W, Reiss K, et al (1996) Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats. Lab Invest 74:86-107
44. Gottleib RA, Burleson KO, Kloner RA, Babior BM, Engler RL (1994) Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J Clin Invest 94:1621-1628
45. Tanaka M, Ito H, Adachi S, et al (1994) Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes. Circ Res 75:426-433
46. Krown KA, Page MT, Nguyen C, et al (1996) Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes: involvement of the sphingolipid signaling cascade in cardiac cell death. J clin Invest 98:2854-2865
47. Jayaraman T, Marks AR (1997) T cells deficient in inositol 1,4,5-trisphosphate receptor are resistant to apoptosis. Mol Cell Biol 17:3005-3012
48. Sugawara H, Kurosaki M, Takata M, Kurosaki T (1997) Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1,4,5-trisphosphate receptors in signal transduction through the B-cell antigen receptor. EMBO J 16:3078-3088
49. Khan AA, Soloski MJ, Sharp AH, et al (1996) Lymphocyte apoptosis: mediation by increased type 3 inositol 1,4,5-trisphosphate receptor. Science 273:503-507
50. Jayaraman T, Ondriasova E, Ondrias K, Harnick D, Marks AR (1995) The inositol 1,4,5-trisphosphate receptor is essential for T cell receptor signaling. Proc Natl Acad Sci USA 92:6007-6011