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Volumn 22, Issue 10, 2007, Pages 1612-1620

RGS18 acts as a negative regulator of osteoclastogenesis by modulating the acid-sensing OGR1/NFAT signaling pathway

Author keywords

Acidosis; G protein; OGR1; Osteoclast; Regulator of G protein signaling protein

Indexed keywords

ANTIBODY; COLONY STIMULATING FACTOR 1; GUANOSINE TRIPHOSPHATE; MESSENGER RNA; OSTEOCLAST DIFFERENTIATION FACTOR; POLYCLONAL ANTIBODY; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; REGULATOR OF G PROTEIN SIGNALING 18; REGULATOR PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFAT C1; UNCLASSIFIED DRUG; ACID; G PROTEIN COUPLED RECEPTOR; GPR68 PROTEIN, MOUSE; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN SUBUNIT; RGS18 PROTEIN, MOUSE; SIGNAL PEPTIDE;

EID: 34548560654     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.070612     Document Type: Article
Times cited : (48)

References (34)
  • 1
    • 0034284970 scopus 로고    scopus 로고
    • Bone resorption by osteoclasts
    • Teitelbaum SL 2000 Bone resorption by osteoclasts. Science 289:1504-1508.
    • (2000) Science , vol.289 , pp. 1504-1508
    • Teitelbaum, S.L.1
  • 2
    • 0043267732 scopus 로고    scopus 로고
    • Genetic regulation of osteoclast development and function
    • Teitelbaum SL, Ross FP 2003 Genetic regulation of osteoclast development and function. Nat Rev Genet 4:638-649.
    • (2003) Nat Rev Genet , vol.4 , pp. 638-649
    • Teitelbaum, S.L.1    Ross, F.P.2
  • 3
    • 0037673945 scopus 로고    scopus 로고
    • Osteoclast differentiation and activation
    • Boyle WJ, Simonet WS, Lacey DL 2003 Osteoclast differentiation and activation. Nature 423:337-342.
    • (2003) Nature , vol.423 , pp. 337-342
    • Boyle, W.J.1    Simonet, W.S.2    Lacey, D.L.3
  • 6
    • 14044249546 scopus 로고    scopus 로고
    • Convergent signaling by acidosis and receptor activator of NF-κB (RANKL) on the calcium/calcineurin/NFAT pathway in osteoclasts
    • Komarova SV, Pereverzev A, Shum JW, Sims SM, Dixon SJ 2005 Convergent signaling by acidosis and receptor activator of NF-κB (RANKL) on the calcium/calcineurin/NFAT pathway in osteoclasts. Proc Natl Acad Sci USA 102:2643-2648.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 2643-2648
    • Komarova, S.V.1    Pereverzev, A.2    Shum, J.W.3    Sims, S.M.4    Dixon, S.J.5
  • 7
    • 33747742467 scopus 로고    scopus 로고
    • Expression of and role for ovarian cancer G-protein-coupled receptor (OGR1) during osteoclastogenesis
    • Yang M, Mailhot G, Birnbaum MJ, MacKay CA, Mason-Savas A, Odgren PR 2006 Expression of and role for ovarian cancer G-protein-coupled receptor (OGR1) during osteoclastogenesis. J Biol Chem 281:23598-23605.
    • (2006) J Biol Chem , vol.281 , pp. 23598-23605
    • Yang, M.1    Mailhot, G.2    Birnbaum, M.J.3    MacKay, C.A.4    Mason-Savas, A.5    Odgren, P.R.6
  • 9
    • 0023062991 scopus 로고
    • G proteins: Transducers of receptor-generated signals
    • Gilman AG 1987 G proteins: Transducers of receptor-generated signals. Annu Rev Biochem 56:615-649.
    • (1987) Annu Rev Biochem , vol.56 , pp. 615-649
    • Gilman, A.G.1
  • 11
    • 0030576518 scopus 로고    scopus 로고
    • GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits
    • Berman DM, Wilkie TM, Gilman AG 1996 GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits. Cell 86:445-452.
    • (1996) Cell , vol.86 , pp. 445-452
    • Berman, D.M.1    Wilkie, T.M.2    Gilman, A.G.3
  • 12
    • 0033783132 scopus 로고    scopus 로고
    • GTPase-activating proteins for heterotrimeric G proteins: Regulators of G protein signaling (RGS) and RGS-like proteins
    • Ross EM, Wilkie TM 2000 GTPase-activating proteins for heterotrimeric G proteins: Regulators of G protein signaling (RGS) and RGS-like proteins. Annu Rev Biochem 69:795-827.
    • (2000) Annu Rev Biochem , vol.69 , pp. 795-827
    • Ross, E.M.1    Wilkie, T.M.2
  • 13
    • 0036490096 scopus 로고    scopus 로고
    • Regulators of G-protein signalling as new central nervous system drug targets
    • Neubig RR, Siderovski DP 2002 Regulators of G-protein signalling as new central nervous system drug targets. Nat Rev Drug Discov 1:187-197.
    • (2002) Nat Rev Drug Discov , vol.1 , pp. 187-197
    • Neubig, R.R.1    Siderovski, D.P.2
  • 14
    • 0242384221 scopus 로고    scopus 로고
    • Physiological actions of regulators of G-protein signaling (RGS) proteins
    • Ishii M, Kurachi Y 2003 Physiological actions of regulators of G-protein signaling (RGS) proteins. Life Sci 74:163-171.
    • (2003) Life Sci , vol.74 , pp. 163-171
    • Ishii, M.1    Kurachi, Y.2
  • 15
    • 0031931196 scopus 로고    scopus 로고
    • Heterotrimeric G protein signaling: Roles in immune function and fine-tuning by RGS proteins
    • Kehrl JH 1998 Heterotrimeric G protein signaling: Roles in immune function and fine-tuning by RGS proteins. Immunity 8:1-10.
    • (1998) Immunity , vol.8 , pp. 1-10
    • Kehrl, J.H.1
  • 16
    • 0033104788 scopus 로고    scopus 로고
    • Regulators of G protein signaling exhibit distinct patterns of gene expression and target G protein specificity in human lymphocytes
    • Beadling C, Druey KM, Richter G, Kehrl JH, Smith KA 1999 Regulators of G protein signaling exhibit distinct patterns of gene expression and target G protein specificity in human lymphocytes. J Immunol 162:2677-2682.
    • (1999) J Immunol , vol.162 , pp. 2677-2682
    • Beadling, C.1    Druey, K.M.2    Richter, G.3    Kehrl, J.H.4    Smith, K.A.5
  • 17
    • 0033578840 scopus 로고    scopus 로고
    • RGS1 is expressed in monocytes and acts as a GTPase-activating protein for G-protein-coupled chemoattractant receptors
    • Denecke B, Meyerdierks A, Bottger EC 1999 RGS1 is expressed in monocytes and acts as a GTPase-activating protein for G-protein-coupled chemoattractant receptors. J Biol Chem 274:26860-26868.
    • (1999) J Biol Chem , vol.274 , pp. 26860-26868
    • Denecke, B.1    Meyerdierks, A.2    Bottger, E.C.3
  • 18
    • 0034192097 scopus 로고    scopus 로고
    • RGS molecule expression in murine B lymphocytes and ability to down-regulate chemotaxis to lymphoid chemokines
    • Reif K, Cyster JG 2000 RGS molecule expression in murine B lymphocytes and ability to down-regulate chemotaxis to lymphoid chemokines. J Immunol 164:4720-4729.
    • (2000) J Immunol , vol.164 , pp. 4720-4729
    • Reif, K.1    Cyster, J.G.2
  • 21
    • 0035803952 scopus 로고    scopus 로고
    • Profile of RGS expression in single rat atrial myocytes
    • Doupnik CA, Xu T, Shinaman JM 2001 Profile of RGS expression in single rat atrial myocytes. Biochim Biophys Acta 1552:97-107.
    • (2001) Biochim Biophys Acta , vol.1552 , pp. 97-107
    • Doupnik, C.A.1    Xu, T.2    Shinaman, J.M.3
  • 23
    • 1242318796 scopus 로고    scopus 로고
    • Fluorescence-based staining for tartrate-resistant acidic phosphatase (TRAP) in osteoclasts combined with other fluorescent dyes and protocols
    • Filgueira L 2004 Fluorescence-based staining for tartrate-resistant acidic phosphatase (TRAP) in osteoclasts combined with other fluorescent dyes and protocols. J Histochem Cytochem 52:411-414.
    • (2004) J Histochem Cytochem , vol.52 , pp. 411-414
    • Filgueira, L.1
  • 25
    • 0035874503 scopus 로고    scopus 로고
    • A novel regulator of G-protein signaling bearing GAP activity for Gαi and Gαq in megakaryocytes
    • Nagata Y, Oda M, Nakata H, Shozaki Y, Kozasa T, Todokoro K 2001 A novel regulator of G-protein signaling bearing GAP activity for Gαi and Gαq in megakaryocytes. Blood 97:3051-3060.
    • (2001) Blood , vol.97 , pp. 3051-3060
    • Nagata, Y.1    Oda, M.2    Nakata, H.3    Shozaki, Y.4    Kozasa, T.5    Todokoro, K.6
  • 27
    • 0020490738 scopus 로고
    • ADP ribosylation of the specific membrane protein of C6 cells by islet-activating protein associated with modification of adenylate cyclase activity
    • Katada T, Ui M 1982 ADP ribosylation of the specific membrane protein of C6 cells by islet-activating protein associated with modification of adenylate cyclase activity. J Biol Chem 257:7210-7216.
    • (1982) J Biol Chem , vol.257 , pp. 7210-7216
    • Katada, T.1    Ui, M.2
  • 28
    • 0021325727 scopus 로고
    • Purification and properties of the inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase
    • Bokoch GM, Katada T, Northup JK, Ui M, Gilman AG 1984 Purification and properties of the inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. J Biol Chem 259:3560-3567.
    • (1984) J Biol Chem , vol.259 , pp. 3560-3567
    • Bokoch, G.M.1    Katada, T.2    Northup, J.K.3    Ui, M.4    Gilman, A.G.5
  • 29
    • 3542998744 scopus 로고    scopus 로고
    • Diverse and essential roles of mammalian vacuolar-type proton pump ATPase: Toward the physiological understanding of inside acidic compartments
    • Sun-Wada GH, Wada Y, Futai M 2004 Diverse and essential roles of mammalian vacuolar-type proton pump ATPase: Toward the physiological understanding of inside acidic compartments. Biochim Biophys Acta 1658:106-114.
    • (2004) Biochim Biophys Acta , vol.1658 , pp. 106-114
    • Sun-Wada, G.H.1    Wada, Y.2    Futai, M.3
  • 30
    • 1642433325 scopus 로고    scopus 로고
    • Recent advances in osteoclast biology and pathological bone resorption
    • Blair HC, Athanasou NA 2004 Recent advances in osteoclast biology and pathological bone resorption. Histol Histopathol 19:189-199.
    • (2004) Histol Histopathol , vol.19 , pp. 189-199
    • Blair, H.C.1    Athanasou, N.A.2
  • 32
    • 4344561709 scopus 로고    scopus 로고
    • Assay of RGS protein modulation by phosphatidylinositides and calmodulin
    • Ishii M, Kurachi Y 2004 Assay of RGS protein modulation by phosphatidylinositides and calmodulin. Methods Enzymol 389:105-118.
    • (2004) Methods Enzymol , vol.389 , pp. 105-118
    • Ishii, M.1    Kurachi, Y.2
  • 33
    • 33845921194 scopus 로고    scopus 로고
    • RGS12 is essential for RANKL-evoked signaling for terminal differentiation of osteoclasts in vitro
    • Yang S, Li Y-P 2007 RGS12 is essential for RANKL-evoked signaling for terminal differentiation of osteoclasts in vitro. J Bone Miner Res 22:45-54.
    • (2007) J Bone Miner Res , vol.22 , pp. 45-54
    • Yang, S.1    Li, Y.-P.2
  • 34
    • 0344442671 scopus 로고    scopus 로고
    • Dynamic expression of RGS4 in the developing nervous system and regulation by the neural type-specific transcription factor Phox2b
    • Grillet N, Dubreuil V, Dufour HD, Brunet JF 2003 Dynamic expression of RGS4 in the developing nervous system and regulation by the neural type-specific transcription factor Phox2b. J Neurosci 23:10613-10621.
    • (2003) J Neurosci , vol.23 , pp. 10613-10621
    • Grillet, N.1    Dubreuil, V.2    Dufour, H.D.3    Brunet, J.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.