-
1
-
-
0029066299
-
A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes
-
Boushey C.J., Beresford S.A., Omenn G.S., and Motulsky A.G. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. JAMA 274 (1995) 1049-1057
-
(1995)
JAMA
, vol.274
, pp. 1049-1057
-
-
Boushey, C.J.1
Beresford, S.A.2
Omenn, G.S.3
Motulsky, A.G.4
-
2
-
-
0030934392
-
Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease
-
Christensen B., Frosst P., Lussier-Cacan S., Selhub J., Goyette P., Rosenblatt D.S., et al. Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease. Arterioscler Thromb Vasc Biol 17 (1997) 569-573
-
(1997)
Arterioscler Thromb Vasc Biol
, vol.17
, pp. 569-573
-
-
Christensen, B.1
Frosst, P.2
Lussier-Cacan, S.3
Selhub, J.4
Goyette, P.5
Rosenblatt, D.S.6
-
3
-
-
1842331509
-
Plasma homocysteine as a risk factor for vascular disease: the European Concerted Action Project
-
Graham I.M., Daly L.E., Refsum H.M., Robinson K., Brattström L.E., Ueland P.M., et al. Plasma homocysteine as a risk factor for vascular disease: the European Concerted Action Project. JAMA 277 (1997) 1775-1781
-
(1997)
JAMA
, vol.277
, pp. 1775-1781
-
-
Graham, I.M.1
Daly, L.E.2
Refsum, H.M.3
Robinson, K.4
Brattström, L.E.5
Ueland, P.M.6
-
4
-
-
1842370239
-
Plasma homocysteine levels and mortality in patients with coronary artery disease
-
Nygard O., Nordrehaug J.E., Refsum H., Ueland P.M., Farstad M., and Vollset S.E. Plasma homocysteine levels and mortality in patients with coronary artery disease. N Engl J Med 337 (1997) 230-236
-
(1997)
N Engl J Med
, vol.337
, pp. 230-236
-
-
Nygard, O.1
Nordrehaug, J.E.2
Refsum, H.3
Ueland, P.M.4
Farstad, M.5
Vollset, S.E.6
-
5
-
-
0033533527
-
Homocysteine and cardiovascular disease: a critical review of the epidemiologic evidence
-
Eikelboom J.W., Lonn E., Genest J., Hankey G., and Yusuf S. Homocysteine and cardiovascular disease: a critical review of the epidemiologic evidence. Ann Intern Med 131 (1999) 363-375
-
(1999)
Ann Intern Med
, vol.131
, pp. 363-375
-
-
Eikelboom, J.W.1
Lonn, E.2
Genest, J.3
Hankey, G.4
Yusuf, S.5
-
6
-
-
0011689010
-
Epidemiology of vascular and thrombotic associations
-
Carmel R., and Jacobsen D. (Eds), Cambridge University Press, Cambridge
-
Verhoef P., and Stampfer M. Epidemiology of vascular and thrombotic associations. In: Carmel R., and Jacobsen D. (Eds). Homocysteine in health and disease (2001), Cambridge University Press, Cambridge 357-370
-
(2001)
Homocysteine in health and disease
, pp. 357-370
-
-
Verhoef, P.1
Stampfer, M.2
-
7
-
-
0036208436
-
Homocysteine and cardiovascular disease: a systematic review of the evidence with special emphasis on case-control studies and nested case-control studies
-
Ford E.S., Smith S.J., Stroup D.F., Steinberg K.K., Mueller P.W., and Thacker S.B. Homocysteine and cardiovascular disease: a systematic review of the evidence with special emphasis on case-control studies and nested case-control studies. Int J Epidemiol 31 (2002) 59-70
-
(2002)
Int J Epidemiol
, vol.31
, pp. 59-70
-
-
Ford, E.S.1
Smith, S.J.2
Stroup, D.F.3
Steinberg, K.K.4
Mueller, P.W.5
Thacker, S.B.6
-
8
-
-
0038572727
-
Homocysteine and coronary artery disease
-
Carmel R., and Jacobsen D. (Eds), Cambridge University Press, Cambridge
-
Robinson K. Homocysteine and coronary artery disease. In: Carmel R., and Jacobsen D. (Eds). Homocysteine in health and disease (2001), Cambridge University Press, Cambridge 371-383
-
(2001)
Homocysteine in health and disease
, pp. 371-383
-
-
Robinson, K.1
-
10
-
-
0033999287
-
Polygenic influence on plasma homocysteine: association of two prevalent mutations, the 844ins68 of cystathionine β-synthase and A2756G of methionine synthase, with lowered plasma homocysteine levels
-
Tsai M.Y., Bignell M., Yang F., Welge B.G., Graham K.J., and Hanson N.Q. Polygenic influence on plasma homocysteine: association of two prevalent mutations, the 844ins68 of cystathionine β-synthase and A2756G of methionine synthase, with lowered plasma homocysteine levels. Atherosclerosis 149 (2000) 131-137
-
(2000)
Atherosclerosis
, vol.149
, pp. 131-137
-
-
Tsai, M.Y.1
Bignell, M.2
Yang, F.3
Welge, B.G.4
Graham, K.J.5
Hanson, N.Q.6
-
11
-
-
0035159261
-
Gene-environment and gene-gene interaction in the determination of plasma homocysteine levels in healthy middle-aged men
-
Dekou V., Gudnason V., Hawe E., Miller G.J., Stansbie D., and Humphries S.E. Gene-environment and gene-gene interaction in the determination of plasma homocysteine levels in healthy middle-aged men. Thromb Haemost 85 (2001) 67-74
-
(2001)
Thromb Haemost
, vol.85
, pp. 67-74
-
-
Dekou, V.1
Gudnason, V.2
Hawe, E.3
Miller, G.J.4
Stansbie, D.5
Humphries, S.E.6
-
12
-
-
0035922669
-
Epidemiological methods for studying genes and environmental factors in complex diseases
-
Clayton D., and McKeigue P.M. Epidemiological methods for studying genes and environmental factors in complex diseases. Lancet 358 (2001) 1356-1360
-
(2001)
Lancet
, vol.358
, pp. 1356-1360
-
-
Clayton, D.1
McKeigue, P.M.2
-
13
-
-
0032531249
-
The human cystathionine β-synthase (CβS) gene: complete sequence, alternative splicing, and polymorphisms
-
Kraus J.P., Oliveriusova J., Sokolova J., Kraus E., Vlcek C., de Franchis R., et al. The human cystathionine β-synthase (CβS) gene: complete sequence, alternative splicing, and polymorphisms. Genomics 52 (1998) 312-324
-
(1998)
Genomics
, vol.52
, pp. 312-324
-
-
Kraus, J.P.1
Oliveriusova, J.2
Sokolova, J.3
Kraus, E.4
Vlcek, C.5
de Franchis, R.6
-
14
-
-
0002051637
-
Polymorphisms of folate and cobalamin metabolism
-
Carmel R., and Jacobsen D. (Eds), Cambridge University Press, Cambridge
-
Rozen R. Polymorphisms of folate and cobalamin metabolism. In: Carmel R., and Jacobsen D. (Eds). Homocysteine in health and disease (2001), Cambridge University Press, Cambridge 259-269
-
(2001)
Homocysteine in health and disease
, pp. 259-269
-
-
Rozen, R.1
-
15
-
-
0021998698
-
Heterozygosity for homocystinuria in premature peripheral and cerebral occlusive arterial disease
-
Boers G.H., Smals A.G., Trijbels F.J., Fowler B., Bakkeren J.A., Schoonderwaldt H.C., et al. Heterozygosity for homocystinuria in premature peripheral and cerebral occlusive arterial disease. N Engl J Med 313 (1985) 709-715
-
(1985)
N Engl J Med
, vol.313
, pp. 709-715
-
-
Boers, G.H.1
Smals, A.G.2
Trijbels, F.J.3
Fowler, B.4
Bakkeren, J.A.5
Schoonderwaldt, H.C.6
-
16
-
-
0025756673
-
Hyperhomocysteinemia: an independent risk factor for vascular disease
-
Clarke R., Daly L., Robinson K., Naughten E., Cahalane S., Fowler B., et al. Hyperhomocysteinemia: an independent risk factor for vascular disease. N Engl J Med 324 (1991) 1149-1155
-
(1991)
N Engl J Med
, vol.324
, pp. 1149-1155
-
-
Clarke, R.1
Daly, L.2
Robinson, K.3
Naughten, E.4
Cahalane, S.5
Fowler, B.6
-
17
-
-
0035159261
-
Gene-environment and gene-gene interaction in the determination of plasma homocysteine levels in healthy middle-aged men
-
Dekou V., Gudnason V., Hawe E., Miller G.J., Stansbie D., and Humphries S.E. Gene-environment and gene-gene interaction in the determination of plasma homocysteine levels in healthy middle-aged men. Thromb Haemost 85 (2001) 67-74
-
(2001)
Thromb Haemost
, vol.85
, pp. 67-74
-
-
Dekou, V.1
Gudnason, V.2
Hawe, E.3
Miller, G.J.4
Stansbie, D.5
Humphries, S.E.6
-
18
-
-
0026691381
-
Age dependency of cystathionine beta-synthase activity in human fibroblasts in homocyst(e)inemia and atherosclerotic vascular disease
-
Nordstrom M., and Kjellstrom T. Age dependency of cystathionine beta-synthase activity in human fibroblasts in homocyst(e)inemia and atherosclerotic vascular disease. Atherosclerosis 94 (1992) 213-221
-
(1992)
Atherosclerosis
, vol.94
, pp. 213-221
-
-
Nordstrom, M.1
Kjellstrom, T.2
-
19
-
-
0028890671
-
Thermolabile 5,10-methylenetetrahydrofolate reductase as a cause of mild hyperhomocysteinemia
-
Engbersen A.M., Franken D.G., Boers G.H., Stevens E.M., Trijbels F.J., and Blom H.J. Thermolabile 5,10-methylenetetrahydrofolate reductase as a cause of mild hyperhomocysteinemia. Am J Hum Genet 56 (1995) 142-150
-
(1995)
Am J Hum Genet
, vol.56
, pp. 142-150
-
-
Engbersen, A.M.1
Franken, D.G.2
Boers, G.H.3
Stevens, E.M.4
Trijbels, F.J.5
Blom, H.J.6
-
20
-
-
0023892344
-
Thermolabile methylenetetrahydrofolate reductase in patients with coronary artery disease
-
Kang S.S., Wong P.W., Zhou J.M., Sora J., Lessick M., Ruggie N., et al. Thermolabile methylenetetrahydrofolate reductase in patients with coronary artery disease. Metabolism 37 (1988) 611-613
-
(1988)
Metabolism
, vol.37
, pp. 611-613
-
-
Kang, S.S.1
Wong, P.W.2
Zhou, J.M.3
Sora, J.4
Lessick, M.5
Ruggie, N.6
-
21
-
-
0023696435
-
Intermediate homocysteinemia: a thermolabile variant of methylenetetrahydrofolate reductase
-
Kang S.S., Zhou J., Wong P.W., Kowalisyn J., and Strokosch G. Intermediate homocysteinemia: a thermolabile variant of methylenetetrahydrofolate reductase. Am J Hum Genet 43 (1998) 414-421
-
(1998)
Am J Hum Genet
, vol.43
, pp. 414-421
-
-
Kang, S.S.1
Zhou, J.2
Wong, P.W.3
Kowalisyn, J.4
Strokosch, G.5
-
22
-
-
0029049553
-
A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase
-
Frosst P., Blom H.J., Milos R., Goyette P., Sheppard C.A., Matthews R.G., et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet 10 (1995) 111-113
-
(1995)
Nat Genet
, vol.10
, pp. 111-113
-
-
Frosst, P.1
Blom, H.J.2
Milos, R.3
Goyette, P.4
Sheppard, C.A.5
Matthews, R.G.6
-
23
-
-
0031886747
-
An enzyme conversion immunoassay for determining total homocysteine in plasma or serum
-
Frantzen F., Faaren A.L., Alfheim I., and Nordhei A.K. An enzyme conversion immunoassay for determining total homocysteine in plasma or serum. Clin Chem 44 (1998) 311-316
-
(1998)
Clin Chem
, vol.44
, pp. 311-316
-
-
Frantzen, F.1
Faaren, A.L.2
Alfheim, I.3
Nordhei, A.K.4
-
24
-
-
0031687887
-
A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity
-
Weisberg I., Tran P., Christensen B., Sibani S., and Rozen R. A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity. Mol Genet Metab 64 (1998) 169-172
-
(1998)
Mol Genet Metab
, vol.64
, pp. 169-172
-
-
Weisberg, I.1
Tran, P.2
Christensen, B.3
Sibani, S.4
Rozen, R.5
-
25
-
-
0035864635
-
Influence of a methionine synthase (D919G) polymorphism on plasma homocysteine and folate levels and relation to risk of myocardial infarction
-
Chen J., Stampfer M.J., Ma J., Selhub J., Malinow M.R., Hennekens C.H., et al. Influence of a methionine synthase (D919G) polymorphism on plasma homocysteine and folate levels and relation to risk of myocardial infarction. Atherosclerosis 154 (2001) 667-672
-
(2001)
Atherosclerosis
, vol.154
, pp. 667-672
-
-
Chen, J.1
Stampfer, M.J.2
Ma, J.3
Selhub, J.4
Malinow, M.R.5
Hennekens, C.H.6
-
26
-
-
0037212592
-
National Heart, Lung and Blood Institute, National Institutes of Health. Effects of polymorphisms of methionine synthase and methionine synthase reductase on total plasma homocysteine in the NHLBI family heart study
-
Jacques P.F., Bostom A.G., Selhub J., Rich S., Ellison R.C., Eckfeldt J.H., et al. National Heart, Lung and Blood Institute, National Institutes of Health. Effects of polymorphisms of methionine synthase and methionine synthase reductase on total plasma homocysteine in the NHLBI family heart study. Atherosclerosis 166 (2003) 49-55
-
(2003)
Atherosclerosis
, vol.166
, pp. 49-55
-
-
Jacques, P.F.1
Bostom, A.G.2
Selhub, J.3
Rich, S.4
Ellison, R.C.5
Eckfeldt, J.H.6
-
27
-
-
0034827634
-
Genetic defects as important factors for moderate hyperhomocysteinemia
-
Geisel J., Zimbelmann I., Schorr H., Knapp J.P., Bodis M., Hübner U., et al. Genetic defects as important factors for moderate hyperhomocysteinemia. Clin Chem Lab Med 39 (2001) 698-704
-
(2001)
Clin Chem Lab Med
, vol.39
, pp. 698-704
-
-
Geisel, J.1
Zimbelmann, I.2
Schorr, H.3
Knapp, J.P.4
Bodis, M.5
Hübner, U.6
-
28
-
-
0031832051
-
Plasma folic acid cutoff value, derived from its relationship with homocyst(e)ine
-
Brouwer D.A., Welten H.T., Reijngoud D.J., van Doormaal J.J., and Muskiet F.A. Plasma folic acid cutoff value, derived from its relationship with homocyst(e)ine. Clin Chem 44 (1998) 1545-1550
-
(1998)
Clin Chem
, vol.44
, pp. 1545-1550
-
-
Brouwer, D.A.1
Welten, H.T.2
Reijngoud, D.J.3
van Doormaal, J.J.4
Muskiet, F.A.5
-
29
-
-
0034033521
-
Hyperhomocysteinemia is chronic alcohoism: relations to folic acid and vitamins B(6) and B(12) status
-
Carvo M.L., and Camilo M.E. Hyperhomocysteinemia is chronic alcohoism: relations to folic acid and vitamins B(6) and B(12) status. Nutrition 16 (2000) 296-302
-
(2000)
Nutrition
, vol.16
, pp. 296-302
-
-
Carvo, M.L.1
Camilo, M.E.2
-
30
-
-
20244366362
-
Genetic causes of mild hyperhomocysteinemia in patients with premature occlusive coronary artery disease
-
Tsai M.Y., Welge B.G., Hanson N.Q., Bignell M.K., Vessey J., Schwichtenberg K., et al. Genetic causes of mild hyperhomocysteinemia in patients with premature occlusive coronary artery disease. Atherosclerosis 143 (1999) 163-170
-
(1999)
Atherosclerosis
, vol.143
, pp. 163-170
-
-
Tsai, M.Y.1
Welge, B.G.2
Hanson, N.Q.3
Bignell, M.K.4
Vessey, J.5
Schwichtenberg, K.6
-
31
-
-
1842483147
-
Homocysteine-indiced thrombosis
-
Edrisinghe S.P. Homocysteine-indiced thrombosis. Br J Biomed Sci (2004) 40-70
-
(2004)
Br J Biomed Sci
, pp. 40-70
-
-
Edrisinghe, S.P.1
-
32
-
-
0036999105
-
Hyperhomocysteinemia, vascular function and atherosclerosis: effects of vitamins
-
Haynes W.G. Hyperhomocysteinemia, vascular function and atherosclerosis: effects of vitamins. Cardiovasc Drugs Ther 16 (2002) 391-399
-
(2002)
Cardiovasc Drugs Ther
, vol.16
, pp. 391-399
-
-
Haynes, W.G.1
-
33
-
-
0028788020
-
Total plasma homocysteine and cardiovascular risk profile. The Hordaland Homocysteine Study
-
Nygard O., Vollset S.E., Refsum H., et al. Total plasma homocysteine and cardiovascular risk profile. The Hordaland Homocysteine Study. J Am Med Assoc 274 (1995) 1526-1533
-
(1995)
J Am Med Assoc
, vol.274
, pp. 1526-1533
-
-
Nygard, O.1
Vollset, S.E.2
Refsum, H.3
-
34
-
-
0036800550
-
Smoking and plasma homocysteine
-
and the European COMAC group
-
O'Callaghan P., Meleady R., Fitzgerald T., Graham I., and and the European COMAC group. Smoking and plasma homocysteine. Eur Heart J 23 (2002) 1580-1586
-
(2002)
Eur Heart J
, vol.23
, pp. 1580-1586
-
-
O'Callaghan, P.1
Meleady, R.2
Fitzgerald, T.3
Graham, I.4
-
35
-
-
0028205719
-
-
Bartecci, CE, Mackenzie, TD, Schrier, RW. The human costs of tobacco use. N Engl J Med 1994; 330: (pt1) 907-12, (pt2) 975-80.
-
-
-
-
36
-
-
0032480790
-
Hyperhomocysteinemia after an oral methionine load acutely impairs endothelial function in adults
-
Bellamy M.F., McDowell I.F., Ramsey M.W., Brownlee M., Bones C., Newcombe R.G., et al. Hyperhomocysteinemia after an oral methionine load acutely impairs endothelial function in adults. Circulation 98 (1998) 1848-1852
-
(1998)
Circulation
, vol.98
, pp. 1848-1852
-
-
Bellamy, M.F.1
McDowell, I.F.2
Ramsey, M.W.3
Brownlee, M.4
Bones, C.5
Newcombe, R.G.6
-
37
-
-
0033538267
-
Impairement of endothelial function by acute hyper-homocysteinemia and reversal by antioxidant vitamins
-
Nappo F., De Rossa N., and Marfella R. Impairement of endothelial function by acute hyper-homocysteinemia and reversal by antioxidant vitamins. JAMA 281 (1996) 2113-2118
-
(1996)
JAMA
, vol.281
, pp. 2113-2118
-
-
Nappo, F.1
De Rossa, N.2
Marfella, R.3
-
38
-
-
0028298171
-
Promotion of vascular smooth muscle cell growth by homocysteine: a link to atherosclerosis
-
Tsai J.C., Perrella M.A., and Yoshizumi. Promotion of vascular smooth muscle cell growth by homocysteine: a link to atherosclerosis. Proc Natl Acad Sci U S A 91 (1994) 6369-6373
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 6369-6373
-
-
Tsai, J.C.1
Perrella, M.A.2
Yoshizumi3
-
39
-
-
0027250615
-
Homocysteine, a risk factor for premature vascular disease and thrombosis, induces tissue factor activity in endothelial cells
-
Freyer R.H., Wilson B.D., Gubler D.B., Fitzgerald L.A., and Rodgers G.M. Homocysteine, a risk factor for premature vascular disease and thrombosis, induces tissue factor activity in endothelial cells. Arterioscler Thromb 13 (1993) 1327-1333
-
(1993)
Arterioscler Thromb
, vol.13
, pp. 1327-1333
-
-
Freyer, R.H.1
Wilson, B.D.2
Gubler, D.B.3
Fitzgerald, L.A.4
Rodgers, G.M.5
-
40
-
-
0023001487
-
Blood coagulation changes in homocystinuria: effects of pyridoxine and other specific therapy
-
Palareti G., Salardi S., and Piazzi S. Blood coagulation changes in homocystinuria: effects of pyridoxine and other specific therapy. J Pediatr 109 (1986) 1001-1006
-
(1986)
J Pediatr
, vol.109
, pp. 1001-1006
-
-
Palareti, G.1
Salardi, S.2
Piazzi, S.3
-
41
-
-
0031971515
-
A second common mutation in the methylene-tetrahydrofolate reductase gene: an additional risk factor for neural-tube defects?
-
van der Put N.M., Gabreels F., Stevens E.M.B., Smeitink J.A., Trijbels F.J., Eskes T.K., et al. A second common mutation in the methylene-tetrahydrofolate reductase gene: an additional risk factor for neural-tube defects?. Am J Hum Genet 62 (1998) 1044-1051
-
(1998)
Am J Hum Genet
, vol.62
, pp. 1044-1051
-
-
van der Put, N.M.1
Gabreels, F.2
Stevens, E.M.B.3
Smeitink, J.A.4
Trijbels, F.J.5
Eskes, T.K.6
-
42
-
-
0036223658
-
Homocysteine and methylenetetrahydrofolate reductase genotype: association with risk of coronary heart disease and relation to inflammatory, hemostatic and lipid parameters
-
Rothenbacher D., Fischer H.G., Hoffmeister A., Hoffmann M.M., März W., Bode G., et al. Homocysteine and methylenetetrahydrofolate reductase genotype: association with risk of coronary heart disease and relation to inflammatory, hemostatic and lipid parameters. Atherosclerosis 162 (2002) 193-200
-
(2002)
Atherosclerosis
, vol.162
, pp. 193-200
-
-
Rothenbacher, D.1
Fischer, H.G.2
Hoffmeister, A.3
Hoffmann, M.M.4
März, W.5
Bode, G.6
-
43
-
-
0035870245
-
Methylenetetrahydrofolate reductase polymorphisms increases risk of esophageal squamous cell carcinoma in a Chinese population
-
Song C., Xing D., Tan W., Wei Q., and Lin D. Methylenetetrahydrofolate reductase polymorphisms increases risk of esophageal squamous cell carcinoma in a Chinese population. Cancer Res 61 (2001) 3272-3275
-
(2001)
Cancer Res
, vol.61
, pp. 3272-3275
-
-
Song, C.1
Xing, D.2
Tan, W.3
Wei, Q.4
Lin, D.5
-
44
-
-
0037384215
-
5,10-methylenetetrahydrofolate reductase 677C→T and 1298A→C mutations are genetic determinants of elevated homocysteine
-
Castro R., Rivera I., Ravasco P., Jakobs C., Blom H.J., Camilo M.E., et al. 5,10-methylenetetrahydrofolate reductase 677C→T and 1298A→C mutations are genetic determinants of elevated homocysteine. Q J Med 96 (2003) 297-303
-
(2003)
Q J Med
, vol.96
, pp. 297-303
-
-
Castro, R.1
Rivera, I.2
Ravasco, P.3
Jakobs, C.4
Blom, H.J.5
Camilo, M.E.6
-
45
-
-
0032923453
-
A second mutation in the methylenetetrahydrofolate reductase gene and the risk of venous thrombotic disease
-
Franco R.F., Morelli V., Lourenco D., Maffei F.H., Tavella M.H., Piccinato C.E., et al. A second mutation in the methylenetetrahydrofolate reductase gene and the risk of venous thrombotic disease. Br J Haematol 105 (1999) 556-559
-
(1999)
Br J Haematol
, vol.105
, pp. 556-559
-
-
Franco, R.F.1
Morelli, V.2
Lourenco, D.3
Maffei, F.H.4
Tavella, M.H.5
Piccinato, C.E.6
-
46
-
-
0032865186
-
A common mutation A1298C in human methylenetetrahydrofolate reductase gene: association with plasma total homocysteine and folate concentrations
-
Friedman G., Goldschmidt N., Friedlander Y., Ben-Yehuda A., Selhub J., Babaey S., et al. A common mutation A1298C in human methylenetetrahydrofolate reductase gene: association with plasma total homocysteine and folate concentrations. J Nutr 129 (1999) 1656-1661
-
(1999)
J Nutr
, vol.129
, pp. 1656-1661
-
-
Friedman, G.1
Goldschmidt, N.2
Friedlander, Y.3
Ben-Yehuda, A.4
Selhub, J.5
Babaey, S.6
-
47
-
-
0036878158
-
No association between the MTHFR A1298C and transcobalamin C776G genetic polymorphisms and hyper-homocysteinemia in thrombotic disease
-
Zetterberg H., Coppala A., D'Angelo A., Palmér M., Rymo L., and Blennow. No association between the MTHFR A1298C and transcobalamin C776G genetic polymorphisms and hyper-homocysteinemia in thrombotic disease. Thromb Res 108 (2003) 127-131
-
(2003)
Thromb Res
, vol.108
, pp. 127-131
-
-
Zetterberg, H.1
Coppala, A.2
D'Angelo, A.3
Palmér, M.4
Rymo, L.5
Blennow6
-
48
-
-
0036019532
-
A1298C methyleneteetrahydrofolate reductase mutation and coronary artery disease: relationships with C677T polymorphism and homocysteine/folate metabolism
-
Friso S., Girelli D., Trabetti E., Stranieri C., Olivieri O., Tinazzi E., et al. A1298C methyleneteetrahydrofolate reductase mutation and coronary artery disease: relationships with C677T polymorphism and homocysteine/folate metabolism. Clin Exp Med 2 (2002) 7-12
-
(2002)
Clin Exp Med
, vol.2
, pp. 7-12
-
-
Friso, S.1
Girelli, D.2
Trabetti, E.3
Stranieri, C.4
Olivieri, O.5
Tinazzi, E.6
-
49
-
-
84984934734
-
MTHFR C677T and A1298C polymorphisms and mutated sequences occurring in cis
-
Zetterberg H., Rymo L., Coppola A., D'Angelo A., Spandidos D.A., and Blennow K. MTHFR C677T and A1298C polymorphisms and mutated sequences occurring in cis. Eur J Hum Genet 10 (2002) 579-582
-
(2002)
Eur J Hum Genet
, vol.10
, pp. 579-582
-
-
Zetterberg, H.1
Rymo, L.2
Coppola, A.3
D'Angelo, A.4
Spandidos, D.A.5
Blennow, K.6
-
50
-
-
0035370968
-
Mutation A1298C methylenetetrahydrofolate reductase: risk for early coronary disease not associated with hyperhomocysteinemia
-
Szczeklik A., Sanak M., Jankowski M., Dropinski J., Czachor R., Musial J., et al. Mutation A1298C methylenetetrahydrofolate reductase: risk for early coronary disease not associated with hyperhomocysteinemia. Am J Med Genet 101 (2001) 36-39
-
(2001)
Am J Med Genet
, vol.101
, pp. 36-39
-
-
Szczeklik, A.1
Sanak, M.2
Jankowski, M.3
Dropinski, J.4
Czachor, R.5
Musial, J.6
-
51
-
-
0030897112
-
Genetic polymorphism of 5,10 methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease
-
Morita H., Taguchi J., Kurihara H., Kitaoka M., Kaneda H., Kurihara Y., et al. Genetic polymorphism of 5,10 methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease. Circulation 95 (1997) 2032-2036
-
(1997)
Circulation
, vol.95
, pp. 2032-2036
-
-
Morita, H.1
Taguchi, J.2
Kurihara, H.3
Kitaoka, M.4
Kaneda, H.5
Kurihara, Y.6
-
52
-
-
0038446637
-
Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults
-
Kluijtmans L.A., Young I.S., Boreham C.A., Murray L., McMaster D., McNulty H., et al. Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults. Blood 101 (2003) 2483-2488
-
(2003)
Blood
, vol.101
, pp. 2483-2488
-
-
Kluijtmans, L.A.1
Young, I.S.2
Boreham, C.A.3
Murray, L.4
McMaster, D.5
McNulty, H.6
-
53
-
-
0035880967
-
MTHFR 677C→T mutation: a predictor of early-onset coronary artery disease
-
Payne D.A., Chamoun A.J., Seifert S.I., and Stouffer G.A. MTHFR 677C→T mutation: a predictor of early-onset coronary artery disease. Thromb Res 103 (2001) 275-279
-
(2001)
Thromb Res
, vol.103
, pp. 275-279
-
-
Payne, D.A.1
Chamoun, A.J.2
Seifert, S.I.3
Stouffer, G.A.4
-
54
-
-
0035552975
-
polymorphisms in the methylenetetrahydrofolate reductase gene: clinical consequences
-
Schwahn B., and Rozen R. polymorphisms in the methylenetetrahydrofolate reductase gene: clinical consequences. Am J Pharmacogenomics 1 (2001) 189-201
-
(2001)
Am J Pharmacogenomics
, vol.1
, pp. 189-201
-
-
Schwahn, B.1
Rozen, R.2
-
55
-
-
0030804226
-
Sequence analysis of the coding region of human methionine synthase: relevance to hyperhomocysteinemia in neural-tube defects and vascular disease
-
van der Put N.M., van der Molen E.F., Kluijtmans L.A., Heil S.G., Trijbels J.M., Eskes T.K., et al. Sequence analysis of the coding region of human methionine synthase: relevance to hyperhomocysteinemia in neural-tube defects and vascular disease. Q J Med 90 (1997) 511-517
-
(1997)
Q J Med
, vol.90
, pp. 511-517
-
-
van der Put, N.M.1
van der Molen, E.F.2
Kluijtmans, L.A.3
Heil, S.G.4
Trijbels, J.M.5
Eskes, T.K.6
-
56
-
-
0032773207
-
Relationship between total plasma homocysteine, polymorphisms of homocysteine metabolism related enzymes, risk factors and coronary artery disease in the Australian hospital-based population
-
Wang X.L., Duarte N., Cai H., Adachi T., Sim A.S., and Cranney G. Relationship between total plasma homocysteine, polymorphisms of homocysteine metabolism related enzymes, risk factors and coronary artery disease in the Australian hospital-based population. Atherosclerosis 146 (1999) 133-140
-
(1999)
Atherosclerosis
, vol.146
, pp. 133-140
-
-
Wang, X.L.1
Duarte, N.2
Cai, H.3
Adachi, T.4
Sim, A.S.5
Cranney, G.6
-
57
-
-
0142196591
-
The 2756A→G variant in the gene encoding methionine synthase: its relation with plasma homocysteine levels and risk of coronary heart disease in a Dutch case-control study
-
Klerk M., Lievers K.J., Kluijtmans L.A., Blom H.J., de Heijer M., Schouten E.G., et al. The 2756A→G variant in the gene encoding methionine synthase: its relation with plasma homocysteine levels and risk of coronary heart disease in a Dutch case-control study. Thromb Res 110 (2003) 87-91
-
(2003)
Thromb Res
, vol.110
, pp. 87-91
-
-
Klerk, M.1
Lievers, K.J.2
Kluijtmans, L.A.3
Blom, H.J.4
de Heijer, M.5
Schouten, E.G.6
-
58
-
-
0034670081
-
Effect of heterozygosity for the methionine synthase 2756A→G mutation on the risk for recurrent cardiovascular events
-
Hyndman M.E., Bridge P.J., Warnica J.W., Fick G., and Parsons H.G. Effect of heterozygosity for the methionine synthase 2756A→G mutation on the risk for recurrent cardiovascular events. Am J Cardiol 86 (2000) 1144-1146
-
(2000)
Am J Cardiol
, vol.86
, pp. 1144-1146
-
-
Hyndman, M.E.1
Bridge, P.J.2
Warnica, J.W.3
Fick, G.4
Parsons, H.G.5
-
59
-
-
0032415394
-
The frequency of a common mutation of the methionine synthase gene in the Australian population and its relation to smoking and coronary artery disease
-
Wang X.L., Cai H., Cranney G., and Wilcken D.E. The frequency of a common mutation of the methionine synthase gene in the Australian population and its relation to smoking and coronary artery disease. J Cardiovasc Risk 5 (1998) 289-295
-
(1998)
J Cardiovasc Risk
, vol.5
, pp. 289-295
-
-
Wang, X.L.1
Cai, H.2
Cranney, G.3
Wilcken, D.E.4
-
60
-
-
0032713815
-
Methionine synthase D919G polymorphism is a significant but modest determinant of circulating homocysteine concentrations
-
Harmon D.L., Shields D.C., Woodside J.V., McMaster D., Yarnell J.W., Young I.S., et al. Methionine synthase D919G polymorphism is a significant but modest determinant of circulating homocysteine concentrations. Genet Epidemiol 17 (1999) 298-309
-
(1999)
Genet Epidemiol
, vol.17
, pp. 298-309
-
-
Harmon, D.L.1
Shields, D.C.2
Woodside, J.V.3
McMaster, D.4
Yarnell, J.W.5
Young, I.S.6
-
61
-
-
0034168107
-
The role of vitamin B12 in fasting hyper-homocysteinemia and its interaction with the homozygous C677T mutation of the MTHFR gene. A case-control study of patients with early-onset thrombotic events
-
D'Angelo A., Coppola A., Madonna P., Fermo I., Pagano A., Mazzola G., et al. The role of vitamin B12 in fasting hyper-homocysteinemia and its interaction with the homozygous C677T mutation of the MTHFR gene. A case-control study of patients with early-onset thrombotic events. Thromb Haemost 83 (2000) 563-570
-
(2000)
Thromb Haemost
, vol.83
, pp. 563-570
-
-
D'Angelo, A.1
Coppola, A.2
Madonna, P.3
Fermo, I.4
Pagano, A.5
Mazzola, G.6
-
62
-
-
0032966833
-
Polymorphism of the methionine synthase gene: association with homocysteine metabolism and late-onset vascular diseases in the Japanese population
-
Morita H., Kurihara H., Sugiyama T., Sugiyama T., Hamada C., Sakai E., et al. Polymorphism of the methionine synthase gene: association with homocysteine metabolism and late-onset vascular diseases in the Japanese population. Arterioscler Thromb Vasc Biol 19 (1999) 298-302
-
(1999)
Arterioscler Thromb Vasc Biol
, vol.19
, pp. 298-302
-
-
Morita, H.1
Kurihara, H.2
Sugiyama, T.3
Sugiyama, T.4
Hamada, C.5
Sakai, E.6
-
63
-
-
0032856882
-
A common variant in methionine synthase reductase combined with low cobalamin increases risk for spina bifida
-
Wilson A., Platt R., Wu Q., Leclerc D., Christensen B., Yang H., et al. A common variant in methionine synthase reductase combined with low cobalamin increases risk for spina bifida. Mol Genet Metab 67 (1999) 317-323
-
(1999)
Mol Genet Metab
, vol.67
, pp. 317-323
-
-
Wilson, A.1
Platt, R.2
Wu, Q.3
Leclerc, D.4
Christensen, B.5
Yang, H.6
-
64
-
-
13144282730
-
Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria
-
Leclerc D., Wilson A., Dumas R., Gafuik C., Song D., Watkins D., et al. Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria. Proc Natl Acad Sci U S A 95 (1998) 3059-3064
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 3059-3064
-
-
Leclerc, D.1
Wilson, A.2
Dumas, R.3
Gafuik, C.4
Song, D.5
Watkins, D.6
-
65
-
-
2342572325
-
Identification of novel polymorphisms and analysis of haplotypes in the methionine synthase reductase gene [abstract]
-
Zavadakova P., Sokolova J., and Kozich V. Identification of novel polymorphisms and analysis of haplotypes in the methionine synthase reductase gene [abstract]. J Inherit Metab Dis 26 (2003) 36
-
(2003)
J Inherit Metab Dis
, vol.26
, pp. 36
-
-
Zavadakova, P.1
Sokolova, J.2
Kozich, V.3
-
66
-
-
2342536908
-
Methionine synthase reductase MTRR 66A→G has no effect on total homocysteine, folate, and vitamin B12 concentrations in renal transplant patients
-
Feix A., Winkelmayer W.C., Eberle C., Sunder-Plassmann G., and Födinger M. Methionine synthase reductase MTRR 66A→G has no effect on total homocysteine, folate, and vitamin B12 concentrations in renal transplant patients. Atherosclerosis 174 (2004) 43-48
-
(2004)
Atherosclerosis
, vol.174
, pp. 43-48
-
-
Feix, A.1
Winkelmayer, W.C.2
Eberle, C.3
Sunder-Plassmann, G.4
Födinger, M.5
-
67
-
-
0034827634
-
Genetic defects as important factors for moderate hyperhomocysteinemia
-
Geisel J., Zimbelmann I., Schorr H., Knapp J.P., Bodis M., Hübner U., et al. Genetic defects as important factors for moderate hyperhomocysteinemia. Clin Chem Lab Med 39 (2001) 698-704
-
(2001)
Clin Chem Lab Med
, vol.39
, pp. 698-704
-
-
Geisel, J.1
Zimbelmann, I.2
Schorr, H.3
Knapp, J.P.4
Bodis, M.5
Hübner, U.6
-
68
-
-
0033912873
-
A common polymorphism in methionine synthase reductase increases risk of premature coronary artery disease
-
Brown C.A., McKinney K.Q., Kaufman J.S., Gravel R.A., and Rozen R. A common polymorphism in methionine synthase reductase increases risk of premature coronary artery disease. J Cardiovasc Risk 7 (2000) 197-200
-
(2000)
J Cardiovasc Risk
, vol.7
, pp. 197-200
-
-
Brown, C.A.1
McKinney, K.Q.2
Kaufman, J.S.3
Gravel, R.A.4
Rozen, R.5
-
69
-
-
0034949476
-
Genetics University of Toronto Thrombophilia Study in Women (GUTTSI): genetic and other risk factors for venous thromboembolism in women
-
Ray J.G., Langman L.J., Vermeulen M.J., Evrovski J., Yeo E.L., and Cole D.E.C. Genetics University of Toronto Thrombophilia Study in Women (GUTTSI): genetic and other risk factors for venous thromboembolism in women. Curr Control Trials Cardiovasc Med 2 (2001) 141-149
-
(2001)
Curr Control Trials Cardiovasc Med
, vol.2
, pp. 141-149
-
-
Ray, J.G.1
Langman, L.J.2
Vermeulen, M.J.3
Evrovski, J.4
Yeo, E.L.5
Cole, D.E.C.6
-
70
-
-
0033004216
-
Serum total homocysteine concentrations in adolescent and adult Americans: results from the third National Health and Nutrition Examination Survey
-
Jacques P.F., Rosenberg I.H., Rogers G., Selhub J., Bowman B.A., Gunter E.W., et al. Serum total homocysteine concentrations in adolescent and adult Americans: results from the third National Health and Nutrition Examination Survey. Am J Clin Nutr 69 (1999) 482-489
-
(1999)
Am J Clin Nutr
, vol.69
, pp. 482-489
-
-
Jacques, P.F.1
Rosenberg, I.H.2
Rogers, G.3
Selhub, J.4
Bowman, B.A.5
Gunter, E.W.6
-
71
-
-
0033846999
-
Polymorphisms in genes involved in folate metabolism as maternal risk factors for Down syndrome
-
Hobbs C.A., Sherman S.L., Yi P., Hopkins S.E., Torfs C.P., Hine R.J., et al. Polymorphisms in genes involved in folate metabolism as maternal risk factors for Down syndrome. Am J Hum Genet 67 (2000) 623
-
(2000)
Am J Hum Genet
, vol.67
, pp. 623
-
-
Hobbs, C.A.1
Sherman, S.L.2
Yi, P.3
Hopkins, S.E.4
Torfs, C.P.5
Hine, R.J.6
|