Reply to ‘mthfr c677t and a1298c polymorphisms and mutated sequences occurring in cis’

European Journal of Human Genetics

Volumn 10, Issue 10, 2002, Pages 579-582

  Zetterberg, Henrik ^a   Coppola, Antonio ^b   D’Angelo, Armando ^c   Spandidos, Demetrios A ^d   Blennow, Kaj ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c IRCCSHS Raffaele   (Italy)

^d UNIVERSITY OF CRETE   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84984934734     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5200863     Document Type: Article

References (14)

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2. van der Put NMJ, Gabreëls F, Stevens EMB et al: A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects?. Am J Hum Genet 1998; 62: 1044-1051.
3. Weisberg I, Tran P, Christensen B, Sibani S, Rozen R: A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity. Mol Genet Metab 1998; 64: 169-172.
4. Chango A, Boisson F, Barbé F et al: The effect of 677C→T and 1298A→C mutations on plasma homocysteine and 5, 10-methylenetetrahydrofolate reductase activity in healthy subjects. Br J Nutr 2000; 83: 593-596.
5. Stegmann K, Ziegler A, Ngo ETKM et al: Linkage disequilibrium of MTHFR genotypes 677C/T-1298A/C in the German population and association studies in probands with neural tube defects (NTD). Am J Med Genet 1999; 87: 23-29.
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8. Rady PL, Tyring SK, Hudnall SD et al: Methylenetetrahydrofolate reductase (MTHFR): the incidence of mutations C677T and A1298C in the Ashkenazi Jewish population. Am J Med Genet 1998; 86: 380-384.
9. Rosenberg N, Murata M, Ikeda Y, Opare-Sem O, Zivelin A, Geffen E, Seligsohn U: The frequent 5, 10-methylenetetrahydrofolate reductase C677T polymorphism is associated with a common haplotype in whites, Japanese, and Africans. Am J Hum Genet 2002; 70: 758-762.
10. Isotalo PA, Wells GA, Donnelly JG: Neonatal and fetal methylenetetrahydrofolate reductase genetic polymorphisms: an examination of C677T and A1298C mutations. Am J Hum Genet 2000; 67: 986-990.
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