Functional analyses of the extra- and intracellular domains of the yeast cell wall integrity sensors Mid2 and Wsc1

FEBS Letters

Volumn 581, Issue 23, 2007, Pages 4495-4500

  Straede, Andrea ^a   Heinisch, Jürgen J ^a  

^a UNIVERSITY OF OSNABRÜCK   (Germany)

Author keywords

Mid2; Stress; Wsc1 Slg1; Yeast

Indexed keywords

CELL MEMBRANE PROTEIN; CHIMERIC PROTEIN; FUNGAL PROTEIN; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; PROTEIN MID2; PROTEIN WSC1; UNCLASSIFIED DRUG;

ARTICLE; CELLULAR DISTRIBUTION; DELETION MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; YEAST CELL;

CALCIUM-BINDING PROTEINS; CELL WALL; CYTOPLASM; GREEN FLUORESCENT PROTEINS; MEMBRANE PROTEINS; MICROSCOPY, FLUORESCENCE; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

SACCHAROMYCES CEREVISIAE;

EID: 34548463794     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2007.08.027     Document Type: Article

References (26)

1. Bowman S.M., and Free S.J. The structure and synthesis of the fungal cell wall. Bioessays 28 (2006) 799-808
2. Carrillo-Munoz A.J., Guisiano G., Ezkurra P.A., and Quindós G. Antifungal agents: mode of action in yeast cells. Rev. Esp. Quimoterap. 19 (2006) 130-139
3. Klis F.M., Boorsma A., and De Groot P.W. Cell wall construction in Saccharomyces cerevisiae. Yeast 23 (2006) 185-202
4. Heinisch J.J. Baker's yeast as a tool for the development of antifungal kinase inhibitors - targeting protein kinase C and the cell integrity pathway. Biochim. Biophys. Acta 1754 (2005) 171-182
5. Levin D.E. Cell wall integrity signaling in Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev. 69 (2005) 262-291
6. Roncero C., and Duran A. Effect of Calcofluor white and Congo red on fungal wall morphogenesis: In vivo activation of chitin polymerization. J. Bacteriol. 163 (1985) 1180-1185
7. Straede A., Corran A., Bundy J., and Heinisch J.J. The effect of tea tree oil and antifungal agents on a reporter for yeast cell integrity signalling. Yeast 24 (2007) 321-334
8. Gray J.V., Ogas J.P., Kamada Y., Stone M., Levin D.E., and Herskowitz I. A role for the Pkcl MAP kinase pathway of Saccharomyces cerevisiae in bud emergence and identification of a putative upstream regulator. EMBO J. 16 (1997) 4924-4937
9. Jacoby J.J., Nilius S.M., and Heinisch J.J. A screen for upstream components of the yeast protein kinase C signal transduction pathway identifies the product of the SLG1 gene. Mol. Gen. Genet. 258 (1998) 148-155
10. Verna J., Lodder A., Lee K., Vagts A., and Ballester R. A family of genes required for maintenance of cell wall integrity and for the stress response in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 94 (1997) 13804-13809
11. Ketela T., Green R., and Bussey H. Saccharomyces cerevisiae Mid2p is a potential cell wall stress sensor and upstream activator of the PKC1-MPK1 cell integrity pathway. J. Bacteriol. 181 (1999) 3330-3340
12. Lommel M., Bagnat M., and Strahl S. Aberrant processing of the WSC family and Mid2p cell surface sensors results in cell death of Saccharomyces cerevisiae O-mannosylation mutants. Mol. Cell. Biol. 24 (2004) 46-57
13. Rajavel M., Philip B., Buehrer B.M., Errede B., and Levin D.E. Mid2 is a putative sensor for cell integrity signaling in Saccharomyces cerevisiae. Mol. Cell. Biol. 19 (1999) 3969-3976
14. Lodder A.L., Lee T.K., and Ballester R. Characterization of the Wscl protein, a putative receptor in the stress response of Saccharomyces cerevisiae. Genetics 152 (1999) 1487-1499
15. Green R., Lesage G., Sdicu A.M., Menard P., and Bussey H. A synthetic analysis of the Saccharomyces cerevisiae stress sensor Mid2p, and identification of a Mid2p-interacting protein, Zeolp, that modulates the PKC1-MPK1 cell integrity pathway. Microbiology 149 (2003) 2487-2499
16. Philip B., and Levin D.E. Wscl and Mid2 are cell surface sensors for cell wall integrity signaling that act through Rom2, a guanine nucleotide exchange factor for Rhol. Mol. Cell. Biol. 21 (2001) 271-280
17. Arvanitidis A., and Heinisch J.J. Studies on the function of yeast phosphofructokinase subunits by in vitro mutagenesis. J. Biol. Chem. 269 (1994) 8911-8918
18. Wach A., Brachat A., Alberti Segui, Rebischung C., and Philippsen P. Heterologous HIS3 marker and GFP reporter modules for PCR-targeting in Saccharomyces cerevisiae. Yeast 13 (1997) 1065-1075
19. Longtine M.S., McKenzie III A., Demarini D.J., Shah N.G., Wach A., Brachat A., Philippsen P., and Pringle J.R. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14 (1998) 953-961
20. Sheff M.A., and Thorn K.S. Optimized cassettes for fluorescent protein tagging in Saccharomyces cerevisiae. Yeast 21 (2004) 661-670
21. Rodicio, R., Buchwald, U., Schmitz, H.P. and Heinisch, J.J. (in press) Dissecting sensor functions in cell wall integrity signaling in Kluyveromyces lactis, Fungal Genet. Biol., doi:10.1016/j.fgb.2007.07.009..
22. Lorberg A., Jacoby J.J., Schmitz H.P., and Heinisch J.J. The PH domain of the yeast GEF Rom2p serves an essential function in vivo. Mol. Genet. Genomics 266 (2001) 505-513
23. Vay H.A., Philip B., and Levin D.E. Mutational analysis of the cytoplasmic domain of the Wscl cell wall stress sensor. Microbiology 150 (2004) 3281-3288
24. Markovich S., Yekutiel A., Shalit I., Shadkchan Y., and Osherov N. Genomic approach to identification of mutations affecting caspofungin susceptibility in Saccharomyces cerevisiae. Antimicrob. Agents Chemother. 48 (2004) 3871-3876
25. Serrano R., Martin H., Casamayor A., and Arino J. Signaling alkaline pH stress in the yeast Saccharomyces cerevisiae through the Wscl cell surface sensor and the Slt2 MAPK pathway. J. Biol. Chem. 281 (2006) 39785-39795
26. Piao H.L., Machado I.M., and Payne G.S. NPFXD-mediated endocytosis is required for polarity and function of a yeast cell wall stress sensor. Mol. Biol. Cell 18 (2007) 57-65