Wsc1 and Mid2 are cell surface sensors for cell wall integrity signaling that act through Rom2, a guanine nucleotide exchange factor for Rho1

Molecular and Cellular Biology

Volumn 21, Issue 1, 2001, Pages 271-280

  Philip, B ^a   Levin, D E ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MANNOSE; MITOGEN ACTIVATED PROTEIN KINASE; PHEROMONE; PROTEIN KINASE C; PROTEIN MID2; PROTEIN ROM2; PROTEIN WSC1; RHO FACTOR; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL WALL; CYTOLYSIS; DELETION MUTANT; GENE MUTATION; GLYCOSYLATION; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN LOCALIZATION; SACCHAROMYCES CEREVISIAE; SENSOR; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; CALCIUM-BINDING PROTEINS; CELL WALL; ENZYME ACTIVATION; GUANINE NUCLEOTIDE EXCHANGE FACTORS; MANNOSYLTRANSFERASES; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MUTATION; PHEROMONES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; RHO GTP-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; TWO-HYBRID SYSTEM TECHNIQUES;

FUNGI; SACCHAROMYCES CEREVISIAE;

EID: 0034749351     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.1.271-280.2001     Document Type: Article

References (51)

1. The N-terminal pleckstrin, coiled-coil, and IQ domains of the exchange factor Ras-GRF act cooperatively to facilitate activation by calcium
2. Coordination of the mating and cell integrity mitogen-activated protein kinase pathways in Saccharomyces cerevisiae
3. A role for the noncatalytic N terminus in the function of Cdc25, a Saccharomyces cerevisiae Ras-guanine nucleotide exchange factor
4. Molecular basis of cell integrity and morphogenesis in Saccharomyces cerevisiae
5. A synthetic lethal screen identifies SLK1, a novel protein kinase homolog implicated in yeast cell morphogenesis and cell growth
6. A second osmosensing signal transduction pathway in yeast
7. The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1,3-β-D-glucan synthase
8. Rho1p, a yeast protein at the interface between cell polarization and morphogenesis
9. Dynamics and organization of MAP kinase signal pathways
10. Structure-function analysis of the dolichyl phosphate-mannose: Protein O-mannosyltransferase ScPmt1p
11. A role for the Pkc1 MAP kinase pathway of Saccharomyces cerevisiae in bud emergence and identification of a putative upstream regulator
12. Yeast/E. coli shuttle vectors with multiple unique restriction sites
13. Site-directed mutagenesis by overlap extension using the polymerase chain reaction
14. 2+ influx and mating
15. Characterization and gene cloning of 1,3-β-D-glucan synthase from Saccharomyces cerevisiae
16. MKK1 and MKK2, which encode Saccharomyces cerevisiae mitogen-activated protein kinase-kinase homologs, function in the pathway mediated by protein kinase C
17. Transformation of intact yeast cells treated with alkali cations
18. A screen for upstream components of the yeast protein kinase C signal transduction pathway identifies the product of the SLG1 gene
19. Why are proteins O-glycosylated?
20. Genome-wide analysis of gene expression regulated by the yeast cell wall integrity signaling pathway
21. The protein kinase C-activated MAP kinase pathway of Saccharomyces cerevisiae mediates a novel aspect of the heat shock response
22. Activation of yeast protein kinase C by Rho1 GTPase
23. Saccharomyces cerevisiae Mid2p is a potential cell wall stress sensor and upstream activator of the PKC1-MPK1 cell integrity pathway
24. Control of cellular morphogenesis by the Ip12/Bem2 GTP-activating protein: Possible role of protein phosphorylation
25. Review: Cell wall assembly in yeast
26. A yeast mitogen-activated protein kinase homolog (Mpk1) mediates signalling by protein kinase C
27. Dominant mutations in a gene encoding a putative protein kinase (BCK1) bypass the requirement for a Saccharomyces cerevisiae protein kinase C homolog
28. Mutants in the S. cerevisiae PKC1 gene display a cell cycle-specific osmotic stability defect
29. Dissecting the protein kinase C/MAP kinase signaling pathway of Saccharomyces cerevisiae
30. The proliferation of MAP kinase signaling pathways in yeast
31. A candidate protein kinase C gene PKC1, is required for the S. cerevisiae cell cycle
32. Characterization of the Wsc1 protein, a putative receptor in the stress response of Saccharomyces cerevisiae
33. The Rho-GEF Rom2p localizes to sites of polarized cell growth and participates in cytoskeletal functions in Saccharomyces cerevisiae
34. Differential expression and function of two homologous subunits of yeast 1,3-β-D-glucan synthase
35. A downstream target of RHO1 small GTP-binding protein is PKC1, a homolog of protein kinase C, which leads to activation of the MAP kinase cascade in Saccharomyces cerevisiae
36. +)-binding domain and shows mating pheromone-stimulated expression in Saccharomyces cerevisiae
37. Rom1p and Rom2p are small GDP/GTP exchange proteins (GEPs) for the Rho1p small GTP-binding protein in Saccharomyces cerevisiae
38. The osmotic integrity of the yeast cell requires a functional PKC1 gene product
39. Interactions between the bud emergence proteins Bem1 and Bem2 and the Rho-type GTPases in yeast
40. Identification of yeast Rho1p GTPase as a regulatory subunit of 1,3-β-glucan synthase
41. Guanine nucleotide exchange factors: Activators of the Ras superfamily of proteins
42. Mid2 is a putative sensor for cell integrity signaling in Saccharomyces cerevisiae
43. Identification of two cell cycle regulated genes affecting the β-1,3-glucan content of cell wall in Saccharomyces cerevisiae
44. The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2
45. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
46. Protein O-mannosylation
47. A family of genes required for the maintenance of cell wall integrity and for the stress response in Saccharomyces cerevisiae
48. Saccharomyces cerevisiae PKC1 encodes a protein kinase C (PKC) homolog with a substrate specificity similar to that of mammalian PKC
49. Characterization of a serum response factor-like protein in Saccharomyces cerevisiae, Rlm1, which has transcriptional activity regulated by the Mpk1 (Slt2) mitogen-activated protein kinase pathway
50. Pheromone signaling in Saccharomyces cerevisiae requires the small GTP-binding protein Cdc42p and its activator CDC24