메뉴 건너뛰기




Volumn 85, Issue 6, 2007, Pages 481-489

Toll-like receptors in the gonads and reproductive tract: Emerging roles in reproductive physiology and pathology

Author keywords

Cancer; Gametogenesis; Infertility; Inflammation; Pregnancy; Prostate

Indexed keywords

TOLL LIKE RECEPTOR;

EID: 34548428385     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/sj.icb.7100086     Document Type: Review
Times cited : (81)

References (114)
  • 1
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol 2004; 4: 499-511.
    • (2004) Nat Rev Immunol , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 4
    • 33846035724 scopus 로고    scopus 로고
    • Mammalian toll-like receptors: From endogenous ligands to tissue regeneration
    • Zhang Z, Schluesener HJ. Mammalian toll-like receptors: from endogenous ligands to tissue regeneration. Cell Mol Life Sci 2006; 63: 2901-2907.
    • (2006) Cell Mol Life Sci , vol.63 , pp. 2901-2907
    • Zhang, Z.1    Schluesener, H.J.2
  • 5
    • 0036200191 scopus 로고    scopus 로고
    • Ovulation: New dimensions and new regulators of the inflammatory-like response
    • Richards JS, Russell DL, Ochsner S, Espey LL. Ovulation: new dimensions and new regulators of the inflammatory-like response. Ann Rev Physiol 2002; 64: 69-92.
    • (2002) Ann Rev Physiol , vol.64 , pp. 69-92
    • Richards, J.S.1    Russell, D.L.2    Ochsner, S.3    Espey, L.L.4
  • 6
    • 0037080024 scopus 로고    scopus 로고
    • Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
    • Zarember KA, Godowski PJ. Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines. J Immunol 2002; 168: 554-561.
    • (2002) J Immunol , vol.168 , pp. 554-561
    • Zarember, K.A.1    Godowski, P.J.2
  • 7
    • 33751552132 scopus 로고    scopus 로고
    • Induced expression of pattern recognition receptors in cumulus oocyte complexes: Novel evidence for innate immune-like functions during ovulation
    • Shimada M, Hernandez-Gonzalez I, Gonzalez-Robanya I, Richards JS. Induced expression of pattern recognition receptors in cumulus oocyte complexes: novel evidence for innate immune-like functions during ovulation. Mol Endocrinol 2006; 20: 3228-3239.
    • (2006) Mol Endocrinol , vol.20 , pp. 3228-3239
    • Shimada, M.1    Hernandez-Gonzalez, I.2    Gonzalez-Robanya, I.3    Richards, J.S.4
  • 8
    • 33846211375 scopus 로고    scopus 로고
    • Inflammation, cancer and chemoresistance: Taking advantage of the toll-like receptor signaling pathway
    • Chen R, Alvero AB, Silasi DA, Mor G. Inflammation, cancer and chemoresistance: taking advantage of the toll-like receptor signaling pathway. Am J Reprod Immunol 2007; 57: 93-107.
    • (2007) Am J Reprod Immunol , vol.57 , pp. 93-107
    • Chen, R.1    Alvero, A.B.2    Silasi, D.A.3    Mor, G.4
  • 9
    • 8444227941 scopus 로고    scopus 로고
    • Endometriosis
    • Giudice LC, Kao LC. Endometriosis. Lancet 2004; 364: 1789-1799.
    • (2004) Lancet , vol.364 , pp. 1789-1799
    • Giudice, L.C.1    Kao, L.C.2
  • 10
    • 33645727988 scopus 로고    scopus 로고
    • TLR-4 signaling promotes tumor growth and paclitaxel chemoresistance in ovarian cancer
    • Kelly MG, Alvero AB, Chen R, Silasi DA, Abrahams VM, Chan S et al. TLR-4 signaling promotes tumor growth and paclitaxel chemoresistance in ovarian cancer. Cancer Res 2006; 66: 3859-3868.
    • (2006) Cancer Res , vol.66 , pp. 3859-3868
    • Kelly, M.G.1    Alvero, A.B.2    Chen, R.3    Silasi, D.A.4    Abrahams, V.M.5    Chan, S.6
  • 11
    • 33645889669 scopus 로고    scopus 로고
    • Melanoma cell lines are responsive in vitro to lipopolysaccharide and express TLR-4
    • Molteni M, Marabella D, Orlandi C, Rossetti C. Melanoma cell lines are responsive in vitro to lipopolysaccharide and express TLR-4. Cancer Lett 2006; 235: 75-83.
    • (2006) Cancer Lett , vol.235 , pp. 75-83
    • Molteni, M.1    Marabella, D.2    Orlandi, C.3    Rossetti, C.4
  • 12
    • 0037206403 scopus 로고    scopus 로고
    • The innate and early immune response to pathogen challenge in the female genital tract and the pivotal role of epithelial cells
    • Quayle AJ. The innate and early immune response to pathogen challenge in the female genital tract and the pivotal role of epithelial cells. J Reprod Immunol 2002; 57: 61-79.
    • (2002) J Reprod Immunol , vol.57 , pp. 61-79
    • Quayle, A.J.1
  • 13
    • 33745755367 scopus 로고    scopus 로고
    • Human oviductal stromal fibroblasts, but not oviductal epithelial cells, express Toll-like receptor 4: The site-specific mucosal immunity of the human fallopian tube against bacterial infection
    • Itoh H, Nasu K, Nishida M, Matsumoto H, Yuge A, Narahara H. Human oviductal stromal fibroblasts, but not oviductal epithelial cells, express Toll-like receptor 4: the site-specific mucosal immunity of the human fallopian tube against bacterial infection. Am J Reprod Immunol 2006; 56: 91-101.
    • (2006) Am J Reprod Immunol , vol.56 , pp. 91-101
    • Itoh, H.1    Nasu, K.2    Nishida, M.3    Matsumoto, H.4    Yuge, A.5    Narahara, H.6
  • 14
    • 19644362276 scopus 로고    scopus 로고
    • Tissue-specific mRNA expression profiles of human toll-like receptors and related genes
    • Nishimura M, Naito S. Tissue-specific mRNA expression profiles of human toll-like receptors and related genes. Biol Pharmaceut Bull 2005; 28: 886-892.
    • (2005) Biol Pharmaceut Bull , vol.28 , pp. 886-892
    • Nishimura, M.1    Naito, S.2
  • 15
    • 27844602914 scopus 로고    scopus 로고
    • A review on pelvic inflammatory disease
    • Barrett S, Taylor C. A review on pelvic inflammatory disease. Int J STD AIDS 2005; 16: 715-720.
    • (2005) Int J STD AIDS , vol.16 , pp. 715-720
    • Barrett, S.1    Taylor, C.2
  • 16
    • 4644269276 scopus 로고    scopus 로고
    • Differential expression of Toll-like receptors 2 and 4 in tissues of the human female reproductive tract
    • Pioli PA, Amiel E, Schaefer TM, Connolly JE, Wira CR, Guyre PM. Differential expression of Toll-like receptors 2 and 4 in tissues of the human female reproductive tract. Infect Immun 2004; 72: 5799-5806.
    • (2004) Infect Immun , vol.72 , pp. 5799-5806
    • Pioli, P.A.1    Amiel, E.2    Schaefer, T.M.3    Connolly, J.E.4    Wira, C.R.5    Guyre, P.M.6
  • 17
    • 20344386219 scopus 로고    scopus 로고
    • Characterization of Toll-like receptors in the female reproductive tract in humans
    • Fazeli A, Bruce C, Anumba DO. Characterization of Toll-like receptors in the female reproductive tract in humans. Human Reprod 2005; 20: 1372-1378.
    • (2005) Human Reprod , vol.20 , pp. 1372-1378
    • Fazeli, A.1    Bruce, C.2    Anumba, D.O.3
  • 18
    • 27144471314 scopus 로고    scopus 로고
    • Pattern recognition molecules activated by Chlamydia muridarum infection of cloned murine oviduct epithelial cell lines
    • Derbigny WA, Kerr MS, Johnson RM. Pattern recognition molecules activated by Chlamydia muridarum infection of cloned murine oviduct epithelial cell lines. J Immunol 2005; 175: 6065-6075.
    • (2005) J Immunol , vol.175 , pp. 6065-6075
    • Derbigny, W.A.1    Kerr, M.S.2    Johnson, R.M.3
  • 19
    • 33846558133 scopus 로고    scopus 로고
    • Human oviductal epithelial cells express Toll-like receptor 3 and respond to double-stranded RNA: Fallopian tube-specific mucosal immunity against viral infection
    • Nasu K, Itoh H, Yuge A, Nishida M, Narahara H. Human oviductal epithelial cells express Toll-like receptor 3 and respond to double-stranded RNA: fallopian tube-specific mucosal immunity against viral infection. Human Reprod 2007; 22: 356-361.
    • (2007) Human Reprod , vol.22 , pp. 356-361
    • Nasu, K.1    Itoh, H.2    Yuge, A.3    Nishida, M.4    Narahara, H.5
  • 20
    • 0344585387 scopus 로고    scopus 로고
    • Toll-like receptor-2, but not Toll-like receptor-4, is essential for development of oviduct pathology in chlamydial genital tract infection
    • Darville T, O'Neill JM, Andrews Jr CW, Nagarajan UM, Stahl L, Ojcius DM. Toll-like receptor-2, but not Toll-like receptor-4, is essential for development of oviduct pathology in chlamydial genital tract infection. J Immunol 2003; 171: 6187-6197.
    • (2003) J Immunol , vol.171 , pp. 6187-6197
    • Darville, T.1    O'Neill, J.M.2    Andrews Jr, C.W.3    Nagarajan, U.M.4    Stahl, L.5    Ojcius, D.M.6
  • 21
    • 0037206409 scopus 로고    scopus 로고
    • Leukocyte networks and human endometrial remodelling
    • Salamonsen LA, Zhang J, Brasted M. Leukocyte networks and human endometrial remodelling. J Reprod Immunol 2002; 57: 95-108.
    • (2002) J Reprod Immunol , vol.57 , pp. 95-108
    • Salamonsen, L.A.1    Zhang, J.2    Brasted, M.3
  • 22
    • 0037351730 scopus 로고    scopus 로고
    • Tissue injury and repair in the female human reproductive tract
    • Salamonsen LA. Tissue injury and repair in the female human reproductive tract. Reproduction 2003; 125: 301-311.
    • (2003) Reproduction , vol.125 , pp. 301-311
    • Salamonsen, L.A.1
  • 24
    • 3042789092 scopus 로고    scopus 로고
    • Toll-like receptor (TLR) expression and TLR-mediated cytokine/chemokine production by human uterine epithelial cells
    • Schaefer TM, Desouza K, Fahey JV, Beagley KW, Wira CR. Toll-like receptor (TLR) expression and TLR-mediated cytokine/chemokine production by human uterine epithelial cells. Immunology 2004; 112: 428-436.
    • (2004) Immunology , vol.112 , pp. 428-436
    • Schaefer, T.M.1    Desouza, K.2    Fahey, J.V.3    Beagley, K.W.4    Wira, C.R.5
  • 25
    • 33646234302 scopus 로고    scopus 로고
    • Expression of Toll-like receptors (TLR) and responsiveness to TLR agonists by polarized mouse uterine epithelial cells in culture
    • Soboll G, Shen L, Wira CR. Expression of Toll-like receptors (TLR) and responsiveness to TLR agonists by polarized mouse uterine epithelial cells in culture. Biol Reprod 2006; 75: 131-139.
    • (2006) Biol Reprod , vol.75 , pp. 131-139
    • Soboll, G.1    Shen, L.2    Wira, C.R.3
  • 26
    • 3543142347 scopus 로고    scopus 로고
    • Expression of Toll-like receptors in human endometrial epithelial cells and cell lines
    • Young SL, Lyddon TD, Jorgenson RL, Misfeldt ML. Expression of Toll-like receptors in human endometrial epithelial cells and cell lines. Am J Reprod Immunol 2004; 52: 67-73.
    • (2004) Am J Reprod Immunol , vol.52 , pp. 67-73
    • Young, S.L.1    Lyddon, T.D.2    Jorgenson, R.L.3    Misfeldt, M.L.4
  • 27
    • 20444397424 scopus 로고    scopus 로고
    • Human endometrial epithelial cells cyclically express Toll-like receptor 3 (TLR3) and exhibit TLR3-dependent responses to dsRNA
    • Jorgenson RL, Young SL, Lesmeister MJ, Lyddon TD, Misfeldt ML. Human endometrial epithelial cells cyclically express Toll-like receptor 3 (TLR3) and exhibit TLR3-dependent responses to dsRNA. Human Immunol 2005; 66: 469-482.
    • (2005) Human Immunol , vol.66 , pp. 469-482
    • Jorgenson, R.L.1    Young, S.L.2    Lesmeister, M.J.3    Lyddon, T.D.4    Misfeldt, M.L.5
  • 28
    • 11844289006 scopus 로고    scopus 로고
    • Innate immunity in the human female reproductive tract: Antiviral response of uterine epithelial cells to the TLR3 agonist poly(I:C)
    • Schaefer TM, Fahey JV, Wright JA, Wira CR. Innate immunity in the human female reproductive tract: antiviral response of uterine epithelial cells to the TLR3 agonist poly(I:C). J Immunol 2005; 174: 992-1002.
    • (2005) J Immunol , vol.174 , pp. 992-1002
    • Schaefer, T.M.1    Fahey, J.V.2    Wright, J.A.3    Wira, C.R.4
  • 29
    • 24944547619 scopus 로고    scopus 로고
    • Migration inhibitory factor secretion by polarized uterine epithelial cells is enhanced in response to the TLR3 agonist poly (I:C)
    • Schaefer TM, Fahey JV, Wright JA, Wira CR. Migration inhibitory factor secretion by polarized uterine epithelial cells is enhanced in response to the TLR3 agonist poly (I:C). Am J Reprod Immunol 2005; 54: 193-202.
    • (2005) Am J Reprod Immunol , vol.54 , pp. 193-202
    • Schaefer, T.M.1    Fahey, J.V.2    Wright, J.A.3    Wira, C.R.4
  • 30
    • 33646550220 scopus 로고    scopus 로고
    • Effect of oestradiol on PAMP-mediated CCL20/MIP-3 α production by mouse uterine epithelial cells in culture
    • Soboll G, Crane-Godreau MA, Lyimo MA, Wira CR. Effect of oestradiol on PAMP-mediated CCL20/MIP-3 α production by mouse uterine epithelial cells in culture. Immunology 2006; 118: 185-194.
    • (2006) Immunology , vol.118 , pp. 185-194
    • Soboll, G.1    Crane-Godreau, M.A.2    Lyimo, M.A.3    Wira, C.R.4
  • 31
    • 33847651871 scopus 로고    scopus 로고
    • Toll-like receptor signalling and the clinical benefits that lie within
    • Verstak B, Hertzog P, Mansell A. Toll-like receptor signalling and the clinical benefits that lie within. Inflamm Res 2007; 56: 1-10.
    • (2007) Inflamm Res , vol.56 , pp. 1-10
    • Verstak, B.1    Hertzog, P.2    Mansell, A.3
  • 34
    • 33750560683 scopus 로고    scopus 로고
    • Endogenous transforming growth factor-β inhibits toll-like receptor mediated activation of human uterine natural killer cells
    • Eriksson M, Meadows SK, Wira CR, Sentman CL. Endogenous transforming growth factor-β inhibits toll-like receptor mediated activation of human uterine natural killer cells. Am J Reprod Immunol 2006; 56: 321-328.
    • (2006) Am J Reprod Immunol , vol.56 , pp. 321-328
    • Eriksson, M.1    Meadows, S.K.2    Wira, C.R.3    Sentman, C.L.4
  • 35
    • 0028540535 scopus 로고
    • Infections related to the menstrual cycle. A study of five otherwise healthy women with recurrent abscesses and a review of the literature
    • Weischer M, Friis-Moller A, Bremmelgaard A. Infections related to the menstrual cycle. A study of five otherwise healthy women with recurrent abscesses and a review of the literature. Infection 1994; 22: 395-400.
    • (1994) Infection , vol.22 , pp. 395-400
    • Weischer, M.1    Friis-Moller, A.2    Bremmelgaard, A.3
  • 36
    • 0346288394 scopus 로고    scopus 로고
    • The mucosal immune system in the human female reproductive tract: Influence of stage of the menstrual cycle and menopause on mucosal immunity in the uterus
    • Glasser SR, Aplin J, Giudice LC, Tabibzadeh S eds, Taylor and Francis: London
    • Wira CR, Fahey JV, White HD, Yeaman GR, Givan AL, Howell AL. The mucosal immune system in the human female reproductive tract: influence of stage of the menstrual cycle and menopause on mucosal immunity in the uterus. In: Glasser SR, Aplin J, Giudice LC, Tabibzadeh S (eds). The Endometrium. Taylor and Francis: London, 2002, pp 371-404.
    • (2002) The Endometrium , pp. 371-404
    • Wira, C.R.1    Fahey, J.V.2    White, H.D.3    Yeaman, G.R.4    Givan, A.L.5    Howell, A.L.6
  • 37
    • 34247620170 scopus 로고    scopus 로고
    • Hirata T, Osuga Y, Hamasaki K, Hirota Y, Nose E, Morimoto C et al. Expression of toll-like receptors 2, 3, 4, and 9 genes in the human endometrium during the menstrual cycle. J Reprod Immunol 2007; 74: 53-60.
    • Hirata T, Osuga Y, Hamasaki K, Hirota Y, Nose E, Morimoto C et al. Expression of toll-like receptors 2, 3, 4, and 9 genes in the human endometrium during the menstrual cycle. J Reprod Immunol 2007; 74: 53-60.
  • 39
    • 0036311544 scopus 로고    scopus 로고
    • Could an infectious trigger explain the differential maternal response to the shared placental pathology of preeclampsia and normotensive intrauterine growth restriction?
    • von Dadelszen P, Magee LA. Could an infectious trigger explain the differential maternal response to the shared placental pathology of preeclampsia and normotensive intrauterine growth restriction? Acta Obstet Gynecol Scand 2002; 81: 642-648.
    • (2002) Acta Obstet Gynecol Scand , vol.81 , pp. 642-648
    • von Dadelszen, P.1    Magee, L.A.2
  • 42
    • 0034457684 scopus 로고    scopus 로고
    • Cloning and characterization of a sub-family of human toll-like receptors: HTLR7, hTLR8 and hTLR9
    • Chuang TH, Ulevitch RJ. Cloning and characterization of a sub-family of human toll-like receptors: hTLR7, hTLR8 and hTLR9. Eur Cytokine Netw 2000; 11: 372-378.
    • (2000) Eur Cytokine Netw , vol.11 , pp. 372-378
    • Chuang, T.H.1    Ulevitch, R.J.2
  • 44
    • 0036379787 scopus 로고    scopus 로고
    • Expression and regulation of the pattern recognition receptors Toll-like receptor-2 and Toll-like receptor-4 in the human placenta
    • Holmlund U, Cebers G, Dahlfors AR, Sandstedt B, Bremme K, Ekstrom ES et al. Expression and regulation of the pattern recognition receptors Toll-like receptor-2 and Toll-like receptor-4 in the human placenta. Immunology 2002; 107: 145-151.
    • (2002) Immunology , vol.107 , pp. 145-151
    • Holmlund, U.1    Cebers, G.2    Dahlfors, A.R.3    Sandstedt, B.4    Bremme, K.5    Ekstrom, E.S.6
  • 45
    • 34247574137 scopus 로고    scopus 로고
    • Innate immune function of the human decidual cell at the maternal-fetal interface
    • Canavan TP, Simhan HN. Innate immune function of the human decidual cell at the maternal-fetal interface. J Reprod Immunol 2007; 74: 46-52.
    • (2007) J Reprod Immunol , vol.74 , pp. 46-52
    • Canavan, T.P.1    Simhan, H.N.2
  • 46
    • 28844479767 scopus 로고    scopus 로고
    • Expression and subcellular localization of TLR-4 in term and first trimester human placenta
    • Beijar EC, Mallard C, Powell TL. Expression and subcellular localization of TLR-4 in term and first trimester human placenta. Placenta 2006; 27: 322-326.
    • (2006) Placenta , vol.27 , pp. 322-326
    • Beijar, E.C.1    Mallard, C.2    Powell, T.L.3
  • 47
    • 33749540348 scopus 로고    scopus 로고
    • Expression and secretion of antiviral factors by trophoblast cells following stimulation by the TLR-3 agonist, Poly(I : C)
    • Abrahams VM, Schaefer TM, Fahey JV, Visintin I, Wright JA, Aldo PB et al. Expression and secretion of antiviral factors by trophoblast cells following stimulation by the TLR-3 agonist, Poly(I : C). Human Reprod 2006; 21: 2432-2439.
    • (2006) Human Reprod , vol.21 , pp. 2432-2439
    • Abrahams, V.M.1    Schaefer, T.M.2    Fahey, J.V.3    Visintin, I.4    Wright, J.A.5    Aldo, P.B.6
  • 48
    • 21444435035 scopus 로고    scopus 로고
    • Toll-like receptors and their role in the trophoblast
    • Abrahams VM, Mor G. Toll-like receptors and their role in the trophoblast. Placenta 2005; 26: 540-547.
    • (2005) Placenta , vol.26 , pp. 540-547
    • Abrahams, V.M.1    Mor, G.2
  • 49
    • 34247574592 scopus 로고    scopus 로고
    • Toll-like receptor 3 agonist induces impairment of uterine vascular remodeling and fetal losses in CBAxDBA/2 mice
    • Zhang J, Wei H, Wu D, Tian Z. Toll-like receptor 3 agonist induces impairment of uterine vascular remodeling and fetal losses in CBAxDBA/2 mice. J Reprod Immunol 2007; 74: 61-67.
    • (2007) J Reprod Immunol , vol.74 , pp. 61-67
    • Zhang, J.1    Wei, H.2    Wu, D.3    Tian, Z.4
  • 50
    • 33747877119 scopus 로고    scopus 로고
    • Ultraviolet-inactivated human cytomegalovirus induces placental syncytiotrophoblast apoptosis in a Toll-like receptor-2 and tumour necrosis factor-α dependent manner
    • Chan G, Guilbert LJ. Ultraviolet-inactivated human cytomegalovirus induces placental syncytiotrophoblast apoptosis in a Toll-like receptor-2 and tumour necrosis factor-α dependent manner. J Pathol 2006; 210: 111-120.
    • (2006) J Pathol , vol.210 , pp. 111-120
    • Chan, G.1    Guilbert, L.J.2
  • 51
    • 0142244180 scopus 로고    scopus 로고
    • A new model for inflammation-induced preterm birth: The role of platelet-activating factor and Toll-like receptor-4
    • Elovitz MA, Wang Z, Chien EK, Rychlik DF, Phillippe M. A new model for inflammation-induced preterm birth: the role of platelet-activating factor and Toll-like receptor-4. Am J Pathol 2003; 163: 2103-2111.
    • (2003) Am J Pathol , vol.163 , pp. 2103-2111
    • Elovitz, M.A.1    Wang, Z.2    Chien, E.K.3    Rychlik, D.F.4    Phillippe, M.5
  • 52
    • 0344306682 scopus 로고    scopus 로고
    • Bacterially-induced preterm labor and regulation of prostaglandin-metabolizing enzyme expression in mice: The role of toll-like receptor 4
    • Wang H, Hirsch E. Bacterially-induced preterm labor and regulation of prostaglandin-metabolizing enzyme expression in mice: the role of toll-like receptor 4. Biol Reprod 2003; 69: 1957-1963.
    • (2003) Biol Reprod , vol.69 , pp. 1957-1963
    • Wang, H.1    Hirsch, E.2
  • 53
    • 1642539988 scopus 로고    scopus 로고
    • Immunohistochemical distribution of Toll-like receptor 4 in term and preterm human placentas from normal and complicated pregnancy including chorioamnionitis
    • Kumazaki K, Nakayama M, Yanagihara I, Suehara N, Wada Y. Immunohistochemical distribution of Toll-like receptor 4 in term and preterm human placentas from normal and complicated pregnancy including chorioamnionitis. Human Pathol 2004; 35: 47-54.
    • (2004) Human Pathol , vol.35 , pp. 47-54
    • Kumazaki, K.1    Nakayama, M.2    Yanagihara, I.3    Suehara, N.4    Wada, Y.5
  • 54
    • 85058202395 scopus 로고    scopus 로고
    • Toll-like receptor 4: A potential link between 'danger signals, ' the innate immune system, and preeclampsia?
    • Kim YM, Romero R, Oh SY, Kim CJ, Kilburn BA, Armant DR et al. Toll-like receptor 4: a potential link between 'danger signals, ' the innate immune system, and preeclampsia? Am J Obstet Gynecol 2005; 193: 921-927.
    • (2005) Am J Obstet Gynecol , vol.193 , pp. 921-927
    • Kim, Y.M.1    Romero, R.2    Oh, S.Y.3    Kim, C.J.4    Kilburn, B.A.5    Armant, D.R.6
  • 55
    • 29144506920 scopus 로고    scopus 로고
    • A role for TLRs in the regulation of immune cell migration by first trimester trophoblast cells
    • Abrahams VM, Visintin I, Aldo PB, Guller S, Romero R, Mor G. A role for TLRs in the regulation of immune cell migration by first trimester trophoblast cells. J Immunol 2005; 175: 8096-8104.
    • (2005) J Immunol , vol.175 , pp. 8096-8104
    • Abrahams, V.M.1    Visintin, I.2    Aldo, P.B.3    Guller, S.4    Romero, R.5    Mor, G.6
  • 56
    • 33947388299 scopus 로고    scopus 로고
    • Toll-like receptor 3 agonist enhances IFN-γ and TNF-α production by murine uterine NK cells
    • Zhang J, Sun R, Wei H, Wu D, Tian Z. Toll-like receptor 3 agonist enhances IFN-γ and TNF-α production by murine uterine NK cells. Int Immunopharmacol 2007; 7: 588-596.
    • (2007) Int Immunopharmacol , vol.7 , pp. 588-596
    • Zhang, J.1    Sun, R.2    Wei, H.3    Wu, D.4    Tian, Z.5
  • 57
    • 8444247042 scopus 로고    scopus 로고
    • Toll-like receptor (TLR)-3, but not TLR4, agonist protects against genital herpes infection in the absence of inflammation seen with CpG DNA
    • Ashkar AA, Yao XD, Gill N, Sajic D, Patrick AJ, Rosenthal KL. Toll-like receptor (TLR)-3, but not TLR4, agonist protects against genital herpes infection in the absence of inflammation seen with CpG DNA. J Infect Dis 2004; 190: 1841-1849.
    • (2004) J Infect Dis , vol.190 , pp. 1841-1849
    • Ashkar, A.A.1    Yao, X.D.2    Gill, N.3    Sajic, D.4    Patrick, A.J.5    Rosenthal, K.L.6
  • 58
    • 0036499128 scopus 로고    scopus 로고
    • Response to Neisseria gonorrhoeae by cervicovaginal epithelial cells occurs in the absence of toll-like receptor 4-mediated signaling
    • Fichorova RN, Cronin AO, Lien E, Anderson DJ, Ingalls RR. Response to Neisseria gonorrhoeae by cervicovaginal epithelial cells occurs in the absence of toll-like receptor 4-mediated signaling. J Immunol 2002; 168: 2424-2432.
    • (2002) J Immunol , vol.168 , pp. 2424-2432
    • Fichorova, R.N.1    Cronin, A.O.2    Lien, E.3    Anderson, D.J.4    Ingalls, R.R.5
  • 59
    • 33646241763 scopus 로고    scopus 로고
    • Effect of toll-like receptor (TLR) agonists on TLR and microbicide expression in uterine and vaginal tissues of the mouse
    • Soboll G, Schaefer TM, Wira CR. Effect of toll-like receptor (TLR) agonists on TLR and microbicide expression in uterine and vaginal tissues of the mouse. Am J Reprod Immunol 2006; 55: 434-446.
    • (2006) Am J Reprod Immunol , vol.55 , pp. 434-446
    • Soboll, G.1    Schaefer, T.M.2    Wira, C.R.3
  • 60
    • 24944511233 scopus 로고    scopus 로고
    • Microbial compounds induce the expression of pro-inflammatory cytokines, chemokines and human β-defensin-2 in vaginal epithelial cells
    • Pivarcsi A, Nagy I, Koreck A, Kis K, Kenderessy-Szabo A, Szell M et al. Microbial compounds induce the expression of pro-inflammatory cytokines, chemokines and human β-defensin-2 in vaginal epithelial cells. Microbes Infect 2005; 7: 1117-1127.
    • (2005) Microbes Infect , vol.7 , pp. 1117-1127
    • Pivarcsi, A.1    Nagy, I.2    Koreck, A.3    Kis, K.4    Kenderessy-Szabo, A.5    Szell, M.6
  • 61
    • 0042208151 scopus 로고    scopus 로고
    • Local delivery of CpG oligodeoxynucleotides induces rapid changes in the genital mucosa and inhibits replication, but not entry, of herpes simplex virus type 2
    • Ashkar AA, Bauer S, Mitchell WJ, Vieira J, Rosenthal KL. Local delivery of CpG oligodeoxynucleotides induces rapid changes in the genital mucosa and inhibits replication, but not entry, of herpes simplex virus type 2. J Virol 2003; 77: 8948-8956.
    • (2003) J Virol , vol.77 , pp. 8948-8956
    • Ashkar, A.A.1    Bauer, S.2    Mitchell, W.J.3    Vieira, J.4    Rosenthal, K.L.5
  • 62
    • 0037223705 scopus 로고    scopus 로고
    • A protective role of locally administered immunostimulatory CpG oligodeoxynucleotide in a mouse model of genital herpes infection
    • Harandi AM, Eriksson K, Holmgren J. A protective role of locally administered immunostimulatory CpG oligodeoxynucleotide in a mouse model of genital herpes infection. J Virol 2003; 77: 953-962.
    • (2003) J Virol , vol.77 , pp. 953-962
    • Harandi, A.M.1    Eriksson, K.2    Holmgren, J.3
  • 63
    • 31444448763 scopus 로고    scopus 로고
    • Treatment of intravaginal HSV-2 infection in mice: A comparison of CpG oligodeoxy-nucleotides and resiquimod (R-848)
    • McCluskie MJ, Cartier JL, Patrick AJ, Sajic D, Weeratna RD, Rosenthal KL et al. Treatment of intravaginal HSV-2 infection in mice: a comparison of CpG oligodeoxy-nucleotides and resiquimod (R-848). Antiviral Res 2006; 69: 77-85.
    • (2006) Antiviral Res , vol.69 , pp. 77-85
    • McCluskie, M.J.1    Cartier, J.L.2    Patrick, A.J.3    Sajic, D.4    Weeratna, R.D.5    Rosenthal, K.L.6
  • 64
    • 33746671960 scopus 로고    scopus 로고
    • A crucial role for plasmacytoid dendritic cells in antiviral protection by CpG ODN-based vaginal microbicide
    • Shen H, Iwasaki A. A crucial role for plasmacytoid dendritic cells in antiviral protection by CpG ODN-based vaginal microbicide. J Clin Invest 2006; 116: 2237-2243.
    • (2006) J Clin Invest , vol.116 , pp. 2237-2243
    • Shen, H.1    Iwasaki, A.2
  • 65
    • 33749497006 scopus 로고    scopus 로고
    • Quantification of poly(I:C)-mediated protection against genital herpes simplex virus type 2 infection
    • Herbst-Kralovetz MM, Pyles RB. Quantification of poly(I:C)-mediated protection against genital herpes simplex virus type 2 infection. J Virol 2006; 80: 9988-9997.
    • (2006) J Virol , vol.80 , pp. 9988-9997
    • Herbst-Kralovetz, M.M.1    Pyles, R.B.2
  • 66
    • 27644446403 scopus 로고    scopus 로고
    • The Toll-like receptor 7 (TLR7) agonist, imiquimod, and the TLR9 agonist, CpG ODN, induce antiviral cytokines and chemokines but do not prevent vaginal transmission of simian immunodeficiency virus when applied intravaginally to rhesus macaques
    • Wang Y, Abel K, Lantz K, Krieg AM, McChesney MB, Miller CJ. The Toll-like receptor 7 (TLR7) agonist, imiquimod, and the TLR9 agonist, CpG ODN, induce antiviral cytokines and chemokines but do not prevent vaginal transmission of simian immunodeficiency virus when applied intravaginally to rhesus macaques. J Virol 2005; 79: 14355-14370.
    • (2005) J Virol , vol.79 , pp. 14355-14370
    • Wang, Y.1    Abel, K.2    Lantz, K.3    Krieg, A.M.4    McChesney, M.B.5    Miller, C.J.6
  • 67
    • 19644362276 scopus 로고    scopus 로고
    • Tissue-specific mRNA expression profiles of human toll-like receptors and related genes
    • Nishimura M, Naito S. Tissue-specific mRNA expression profiles of human toll-like receptors and related genes. Biol Pharmaceut Bull 2005; 28: 886-892.
    • (2005) Biol Pharmaceut Bull , vol.28 , pp. 886-892
    • Nishimura, M.1    Naito, S.2
  • 68
    • 33750828914 scopus 로고    scopus 로고
    • Sertoli cells initiate testicular innate immune responses through TLR activation
    • Riccioli A, Starace D, Galli R, Fuso A, Scarpa S, Palombi F et al. Sertoli cells initiate testicular innate immune responses through TLR activation. J Immunol 2006; 177: 7122-7130.
    • (2006) J Immunol , vol.177 , pp. 7122-7130
    • Riccioli, A.1    Starace, D.2    Galli, R.3    Fuso, A.4    Scarpa, S.5    Palombi, F.6
  • 69
    • 34249749938 scopus 로고    scopus 로고
    • Members of the Toll-like receptor family of innate immunity pattern-recognition receptors are abundant in the male rat reproductive tract
    • Palladino MA, Johnson TA, Gupta R, Chapman JL, Ojha P. Members of the Toll-like receptor family of innate immunity pattern-recognition receptors are abundant in the male rat reproductive tract. Biol Reprod 2007; 76: 958-964.
    • (2007) Biol Reprod , vol.76 , pp. 958-964
    • Palladino, M.A.1    Johnson, T.A.2    Gupta, R.3    Chapman, J.L.4    Ojha, P.5
  • 72
  • 74
    • 0025973916 scopus 로고
    • Variation in sperm penetration assay related to viral illness
    • Buch JP, Havlovec SK. Variation in sperm penetration assay related to viral illness. Fertil Steril 1991; 55: 844-846.
    • (1991) Fertil Steril , vol.55 , pp. 844-846
    • Buch, J.P.1    Havlovec, S.K.2
  • 75
    • 0023803386 scopus 로고
    • Sex hormone status of male patients with rheumatoid arthritis: Evidence of low serum concentrations of testosterone at baseline and after human chorionic gonadotropin stimulation
    • Cutolo M, Balleari E, Giusti M, Monachesi M, Accardo S. Sex hormone status of male patients with rheumatoid arthritis: evidence of low serum concentrations of testosterone at baseline and after human chorionic gonadotropin stimulation. Arthritis Rheum 1988; 31: 1314-1317.
    • (1988) Arthritis Rheum , vol.31 , pp. 1314-1317
    • Cutolo, M.1    Balleari, E.2    Giusti, M.3    Monachesi, M.4    Accardo, S.5
  • 76
    • 33845984004 scopus 로고    scopus 로고
    • A stereological analysis of the response of spermatogenesis to an acute inflammatory episode in adult rats
    • Liew SH, Meachem SJ, Hedger MP. A stereological analysis of the response of spermatogenesis to an acute inflammatory episode in adult rats. J Androl 2007; 28: 176-185.
    • (2007) J Androl , vol.28 , pp. 176-185
    • Liew, S.H.1    Meachem, S.J.2    Hedger, M.P.3
  • 77
    • 0034463922 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide-induced inflammation compromises testicular function at multiple levels in vivo
    • O'Bryan MK, Schlatt S, Phillips DJ, de Kretser DM, Hedger MP. Bacterial lipopolysaccharide-induced inflammation compromises testicular function at multiple levels in vivo. Endocrinology 2000; 141: 238-246.
    • (2000) Endocrinology , vol.141 , pp. 238-246
    • O'Bryan, M.K.1    Schlatt, S.2    Phillips, D.J.3    de Kretser, D.M.4    Hedger, M.P.5
  • 78
    • 0035101072 scopus 로고    scopus 로고
    • The in vitro role of tumour necrosis factor-α and interleukin-6 in the hypothalamic-pituitary gonadal axis
    • Russell SH, Small CJ, Stanley SA, Franks S, Ghatei MA, Bloom SR. The in vitro role of tumour necrosis factor-α and interleukin-6 in the hypothalamic-pituitary gonadal axis. J Neuroendocrinol 2001; 13: 296-301.
    • (2001) J Neuroendocrinol , vol.13 , pp. 296-301
    • Russell, S.H.1    Small, C.J.2    Stanley, S.A.3    Franks, S.4    Ghatei, M.A.5    Bloom, S.R.6
  • 79
    • 0038744340 scopus 로고    scopus 로고
    • Cooperation between toll-like receptor 2 and 4 in the brain of mice challenged with cell wall components derived from gram-negative and gram-positive bacteria
    • Laflamme N, Echchannaoui H, Landmann R, Rivest S. Cooperation between toll-like receptor 2 and 4 in the brain of mice challenged with cell wall components derived from gram-negative and gram-positive bacteria. Eur J Immunol 2003; 33: 1127-1138.
    • (2003) Eur J Immunol , vol.33 , pp. 1127-1138
    • Laflamme, N.1    Echchannaoui, H.2    Landmann, R.3    Rivest, S.4
  • 80
    • 0034522674 scopus 로고    scopus 로고
    • Lipopolysaccharide directly stimulates the intrapituitary interleukin-6 production by folliculostellate cells via specific receptors and the p38α mitogen-activated protein kinase/nuclear factor-κB pathway
    • Lohrer P, Gloddek J, Nagashima AC, Korali Z, Hopfner U, Pereda MP et al. Lipopolysaccharide directly stimulates the intrapituitary interleukin-6 production by folliculostellate cells via specific receptors and the p38α mitogen-activated protein kinase/nuclear factor-κB pathway. Endocrinology 2000; 141: 4457-4465.
    • (2000) Endocrinology , vol.141 , pp. 4457-4465
    • Lohrer, P.1    Gloddek, J.2    Nagashima, A.C.3    Korali, Z.4    Hopfner, U.5    Pereda, M.P.6
  • 81
    • 0028017810 scopus 로고
    • Leukocyte populations of the adult rat testis following removal of the Leydig cells by treatment with ethane dimethane sulfonate and subcutaneous testosterone implants
    • Wang J, Wreford NG, Lan HY, Atkins R, Hedger MP. Leukocyte populations of the adult rat testis following removal of the Leydig cells by treatment with ethane dimethane sulfonate and subcutaneous testosterone implants. Biol Reprod 1994; 51: 551-561.
    • (1994) Biol Reprod , vol.51 , pp. 551-561
    • Wang, J.1    Wreford, N.G.2    Lan, H.Y.3    Atkins, R.4    Hedger, M.P.5
  • 82
    • 0031688693 scopus 로고    scopus 로고
    • Interactions between testicular macrophages and Leydig cells
    • Hutson JC. Interactions between testicular macrophages and Leydig cells. J Androl 1998; 19: 394-398.
    • (1998) J Androl , vol.19 , pp. 394-398
    • Hutson, J.C.1
  • 83
    • 0027475198 scopus 로고
    • The effect of testicular macrophages and interleukin-1 on testosterone production by purified adult rat Leydig cells cultured under in vitro maintenance conditions
    • Sun XR, Hedger MP, Risbridger GP. The effect of testicular macrophages and interleukin-1 on testosterone production by purified adult rat Leydig cells cultured under in vitro maintenance conditions. Endocrinology 1993; 132: 186-192.
    • (1993) Endocrinology , vol.132 , pp. 186-192
    • Sun, X.R.1    Hedger, M.P.2    Risbridger, G.P.3
  • 84
    • 0027975606 scopus 로고
    • Immune - endocrine interactions in the mouse testis: Cytokine-mediated inhibition of Leydig cell steroidogenesis
    • Xiong Y, Hales DB. Immune - endocrine interactions in the mouse testis: cytokine-mediated inhibition of Leydig cell steroidogenesis. Endocr J 1994; 2: 223-228.
    • (1994) Endocr J , vol.2 , pp. 223-228
    • Xiong, Y.1    Hales, D.B.2
  • 85
    • 0031767025 scopus 로고    scopus 로고
    • Nitric oxide is a mediator of the inhibitory effect of activated macrophages on production of androgen by the Leydig cell of the mouse
    • Pomerantz DK, Pitelka V. Nitric oxide is a mediator of the inhibitory effect of activated macrophages on production of androgen by the Leydig cell of the mouse. Endocrinology 1998; 139: 922-931.
    • (1998) Endocrinology , vol.139 , pp. 922-931
    • Pomerantz, D.K.1    Pitelka, V.2
  • 86
    • 0027535555 scopus 로고
    • Identification, ontogeny, and regulation of an interleukin-6-like factor in the rat seminiferous tubule
    • Syed V, Gerard N, Kaipia A, Bardin CW, Parvinen M, Jegou B. Identification, ontogeny, and regulation of an interleukin-6-like factor in the rat seminiferous tubule. Endocrinology 1993; 132: 293-299.
    • (1993) Endocrinology , vol.132 , pp. 293-299
    • Syed, V.1    Gerard, N.2    Kaipia, A.3    Bardin, C.W.4    Parvinen, M.5    Jegou, B.6
  • 87
    • 0029060690 scopus 로고
    • Residual bodies activate Sertoli cell interleukin-1α (IL-1α) release, which triggers IL-6 production by an autocrine mechanism, through the lipoxygenase pathway
    • Syed V, Stéphan JP, Gérard N, Legrand A, Parvinen M, Bardin CW et al. Residual bodies activate Sertoli cell interleukin-1α (IL-1α) release, which triggers IL-6 production by an autocrine mechanism, through the lipoxygenase pathway. Endocrinology 1995; 136: 3070-3078.
    • (1995) Endocrinology , vol.136 , pp. 3070-3078
    • Syed, V.1    Stéphan, J.P.2    Gérard, N.3    Legrand, A.4    Parvinen, M.5    Bardin, C.W.6
  • 88
    • 0344004079 scopus 로고    scopus 로고
    • Regulation of Sertoli cell IL-1 and IL-6 production in vitro
    • Stéphan JP, Syed V, Jégou B. Regulation of Sertoli cell IL-1 and IL-6 production in vitro. Mol Cell Endocrinol 1997; 134: 109-118.
    • (1997) Mol Cell Endocrinol , vol.134 , pp. 109-118
    • Stéphan, J.P.1    Syed, V.2    Jégou, B.3
  • 89
    • 2642602085 scopus 로고    scopus 로고
    • In vitro regulation of an inducible-type NO synthase in the rat seminiferous tubule cells
    • Bauché F, Stéphan JP, Touzalin AM, Jégou B. In vitro regulation of an inducible-type NO synthase in the rat seminiferous tubule cells. Biol Reprod 1998; 58: 431-438.
    • (1998) Biol Reprod , vol.58 , pp. 431-438
    • Bauché, F.1    Stéphan, J.P.2    Touzalin, A.M.3    Jégou, B.4
  • 90
    • 0038310271 scopus 로고    scopus 로고
    • Regulation of Sertoli cell tight junction dynamics in the rat testis via the nitric oxide synthase/soluble guanylate cyclase/3′, 5′-cyclic guanosine monophosphate/protein kinase G signaling pathway: An in vitro study
    • Lee NP, Cheng CY. Regulation of Sertoli cell tight junction dynamics in the rat testis via the nitric oxide synthase/soluble guanylate cyclase/3′, 5′-cyclic guanosine monophosphate/protein kinase G signaling pathway: an in vitro study. Endocrinology 2003; 144: 3114-3129.
    • (2003) Endocrinology , vol.144 , pp. 3114-3129
    • Lee, N.P.1    Cheng, C.Y.2
  • 91
    • 0028918585 scopus 로고
    • Function of interleukin-6 as an inhibitor of meiotic DNA synthesis in the rat seminiferous epithelium
    • Hakovirta H, Syed V, Jégou B, Parvinen M. Function of interleukin-6 as an inhibitor of meiotic DNA synthesis in the rat seminiferous epithelium. Mol Cell Endocrinol 1995; 108: 193-198.
    • (1995) Mol Cell Endocrinol , vol.108 , pp. 193-198
    • Hakovirta, H.1    Syed, V.2    Jégou, B.3    Parvinen, M.4
  • 93
    • 0026004459 scopus 로고
    • In vitro stimulation of stage-specific deoxyribonucleic acid synthesis in rat seminiferous tubule segments by interleukin-1α
    • Parvinen M, Söder O, Mali P, Fröysa B, Ritzén EM. In vitro stimulation of stage-specific deoxyribonucleic acid synthesis in rat seminiferous tubule segments by interleukin-1α. Endocrinology 1991; 129: 1614-1620.
    • (1991) Endocrinology , vol.129 , pp. 1614-1620
    • Parvinen, M.1    Söder, O.2    Mali, P.3    Fröysa, B.4    Ritzén, E.M.5
  • 94
    • 0025910546 scopus 로고
    • Production and secretion of an interleukin-1-like factor is stage-dependent and correlates with spermatogonial DNA synthesis in the rat seminiferous epithelium
    • Söder O, Syed V, Callard GV, Toppari J, Pöllänen P, Parvinen M et al. Production and secretion of an interleukin-1-like factor is stage-dependent and correlates with spermatogonial DNA synthesis in the rat seminiferous epithelium. Int J Androl 1991; 14: 223-231.
    • (1991) Int J Androl , vol.14 , pp. 223-231
    • Söder, O.1    Syed, V.2    Callard, G.V.3    Toppari, J.4    Pöllänen, P.5    Parvinen, M.6
  • 95
    • 0027484186 scopus 로고
    • Effects of activin-A, inhibin-A, and transforming growth factor-β1 on stage-specific deoxyribonucleic acid synthesis during rat seminiferous epithelial cycle
    • Hakovirta H, Kaipia A, Söder O, Parvinen M. Effects of activin-A, inhibin-A, and transforming growth factor-β1 on stage-specific deoxyribonucleic acid synthesis during rat seminiferous epithelial cycle. Endocrinology 1993; 133: 1664-1668.
    • (1993) Endocrinology , vol.133 , pp. 1664-1668
    • Hakovirta, H.1    Kaipia, A.2    Söder, O.3    Parvinen, M.4
  • 96
    • 0025685417 scopus 로고
    • Activin stimulates spermatogonial proliferation in germ-Sertoli cell cocultures from immature rat testis
    • Mather JP, Attie KM, Woodruff TK, Rice GC, Phillips DM. Activin stimulates spermatogonial proliferation in germ-Sertoli cell cocultures from immature rat testis. Endocrinology 1990; 127: 3206-3214.
    • (1990) Endocrinology , vol.127 , pp. 3206-3214
    • Mather, J.P.1    Attie, K.M.2    Woodruff, T.K.3    Rice, G.C.4    Phillips, D.M.5
  • 97
    • 0030931403 scopus 로고    scopus 로고
    • Identification of IL-6 as one of the important cytokines responsible for the ability of mononuclear cells to stimulate Sertoli cell functions
    • Hoeben E, Wuyts A, Proost P, Van Damme J, Verhoeven G. Identification of IL-6 as one of the important cytokines responsible for the ability of mononuclear cells to stimulate Sertoli cell functions. Mol Cell Endocrinol 1997; 132: 149-160.
    • (1997) Mol Cell Endocrinol , vol.132 , pp. 149-160
    • Hoeben, E.1    Wuyts, A.2    Proost, P.3    Van Damme, J.4    Verhoeven, G.5
  • 98
    • 0031597419 scopus 로고    scopus 로고
    • Interleukin 1α stimulates lactate dehydrogenase A expression and lactate production in cultured porcine Sertoli cells
    • Nehar D, Mauduit C, Boussouar F, Benahmed M. Interleukin 1α stimulates lactate dehydrogenase A expression and lactate production in cultured porcine Sertoli cells. Biol Reprod 1998; 59: 1425-1432.
    • (1998) Biol Reprod , vol.59 , pp. 1425-1432
    • Nehar, D.1    Mauduit, C.2    Boussouar, F.3    Benahmed, M.4
  • 99
    • 0026740931 scopus 로고
    • Lipopolysaccharide, latex beads and residual bodies are potent activators of Sertoli cell interleukin-1α production
    • Gérard N, Syed V, Jégou B. Lipopolysaccharide, latex beads and residual bodies are potent activators of Sertoli cell interleukin-1α production. Biochem Biophys Res Commun 1992; 185: 154-161.
    • (1992) Biochem Biophys Res Commun , vol.185 , pp. 154-161
    • Gérard, N.1    Syed, V.2    Jégou, B.3
  • 100
    • 33747887227 scopus 로고    scopus 로고
    • Regulated production of activin A and inhibin B throughout the cycle of the seminiferous epithelium in the rat
    • Okuma Y, O'Connor AE, Hayashi T, Loveland KL, de Kretser DM, Hedger MP. Regulated production of activin A and inhibin B throughout the cycle of the seminiferous epithelium in the rat. J Endocrinol 2006; 190: 331-340.
    • (2006) J Endocrinol , vol.190 , pp. 331-340
    • Okuma, Y.1    O'Connor, A.E.2    Hayashi, T.3    Loveland, K.L.4    de Kretser, D.M.5    Hedger, M.P.6
  • 101
    • 18644383289 scopus 로고    scopus 로고
    • Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and - independent pathways
    • Yasuda K, Yu P, Kirschning CJ, Schlatter B, Schmitz F, Heit A et al. Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and - independent pathways. J Immunol 2005; 174: 6129-6136.
    • (2005) J Immunol , vol.174 , pp. 6129-6136
    • Yasuda, K.1    Yu, P.2    Kirschning, C.J.3    Schlatter, B.4    Schmitz, F.5    Heit, A.6
  • 102
  • 103
    • 33750031603 scopus 로고    scopus 로고
    • The high mobility group box chromosomal protein 1 is expressed in the human and rat testis where it may function as an antibacterial factor
    • Zetterström CK, Strand ML, Söder O. The high mobility group box chromosomal protein 1 is expressed in the human and rat testis where it may function as an antibacterial factor. Hum Reprod 2006; 21: 2801-2809.
    • (2006) Hum Reprod , vol.21 , pp. 2801-2809
    • Zetterström, C.K.1    Strand, M.L.2    Söder, O.3
  • 104
    • 33746731651 scopus 로고    scopus 로고
    • HMGB1 signals through toll-like receptor (TLR) 4 and TLR2
    • Yu M, Wang H, Ding A, Golenbock DT, Latz E, Czura CJ et al. HMGB1 signals through toll-like receptor (TLR) 4 and TLR2. Shock 2006; 26: 174-179.
    • (2006) Shock , vol.26 , pp. 174-179
    • Yu, M.1    Wang, H.2    Ding, A.3    Golenbock, D.T.4    Latz, E.5    Czura, C.J.6
  • 105
    • 20444398156 scopus 로고    scopus 로고
    • Lipopolysaccharide-binding protein is produced in the epididymis and associated with spermatozoa and prostasomes
    • Malm J, Nordahl EA, Bjartell A, Sørensen OE, Frohm B, Dentener MA et al. Lipopolysaccharide-binding protein is produced in the epididymis and associated with spermatozoa and prostasomes. J Reprod Immunol 2005; 66: 33-43.
    • (2005) J Reprod Immunol , vol.66 , pp. 33-43
    • Malm, J.1    Nordahl, E.A.2    Bjartell, A.3    Sørensen, O.E.4    Frohm, B.5    Dentener, M.A.6
  • 106
    • 33845528962 scopus 로고    scopus 로고
    • Susceptibility of prostate epithelial cells to Chlamydia muridarum infection and their role in innate immunity by recruitment of intracellular Toll-like receptors 4 and 2 and MyD88 to the inclusion
    • Mackern-Oberti JP, Maccioni M, Cuffini C, Gatti G, Rivero VE. Susceptibility of prostate epithelial cells to Chlamydia muridarum infection and their role in innate immunity by recruitment of intracellular Toll-like receptors 4 and 2 and MyD88 to the inclusion. Infect Immun 2006; 74: 6973-6981.
    • (2006) Infect Immun , vol.74 , pp. 6973-6981
    • Mackern-Oberti, J.P.1    Maccioni, M.2    Cuffini, C.3    Gatti, G.4    Rivero, V.E.5
  • 107
    • 33750881157 scopus 로고    scopus 로고
    • Toll-like receptor 4 in rat prostate: Modulation by testosterone and acute bacterial infection in epithelial and stromal cells
    • Quintar AA, Roth FD, De Paul AL, Aoki A, Maldonado CA. Toll-like receptor 4 in rat prostate: modulation by testosterone and acute bacterial infection in epithelial and stromal cells. Biol Reprod 2006; 75: 664-672.
    • (2006) Biol Reprod , vol.75 , pp. 664-672
    • Quintar, A.A.1    Roth, F.D.2    De Paul, A.L.3    Aoki, A.4    Maldonado, C.A.5
  • 108
    • 33745310156 scopus 로고    scopus 로고
    • Prostate epithelial cells can act as early sensors of infection by up-regulating TLR4 expression and proinflammatory mediators upon LPS stimulation
    • Gatti G, Rivero V, Motrich RD, Maccioni M. Prostate epithelial cells can act as early sensors of infection by up-regulating TLR4 expression and proinflammatory mediators upon LPS stimulation. J Leukoc Biol 2006; 79: 989-998.
    • (2006) J Leukoc Biol , vol.79 , pp. 989-998
    • Gatti, G.1    Rivero, V.2    Motrich, R.D.3    Maccioni, M.4
  • 110
    • 33644767300 scopus 로고    scopus 로고
    • Prostate cell lines secrete IL-8 in response to Mycoplasma hominis through Toll-like receptor 2-mediated mechanism
    • Takeyama K, Mitsuzawa H, Shimizu T, Konishi M, Nishitani C, Sano H et al. Prostate cell lines secrete IL-8 in response to Mycoplasma hominis through Toll-like receptor 2-mediated mechanism. Prostate 2006; 66: 386-391.
    • (2006) Prostate , vol.66 , pp. 386-391
    • Takeyama, K.1    Mitsuzawa, H.2    Shimizu, T.3    Konishi, M.4    Nishitani, C.5    Sano, H.6
  • 112
    • 8444235603 scopus 로고    scopus 로고
    • Sequence variants of toll-like receptor 4 are associated with prostate cancer risk: Results fromthe CAncer Prostate in Sweden Study
    • Zheng SL, Augustsson-Balter K, Chang B, Hedelin M, Li L, Adami HO et al. Sequence variants of toll-like receptor 4 are associated with prostate cancer risk: results fromthe CAncer Prostate in Sweden Study. Cancer Res 2004; 64: 2918-2922.
    • (2004) Cancer Res , vol.64 , pp. 2918-2922
    • Zheng, S.L.1    Augustsson-Balter, K.2    Chang, B.3    Hedelin, M.4    Li, L.5    Adami, H.O.6
  • 113
    • 29244441698 scopus 로고    scopus 로고
    • Sequence variants of Toll-like receptor 4 and susceptibility to prostate cancer
    • Chen YC, Giovannucci E, Lazarus R, Kraft P, Ketkar S, Hunter DJ. Sequence variants of Toll-like receptor 4 and susceptibility to prostate cancer. Cancer Res 2005; 65: 11771-11778.
    • (2005) Cancer Res , vol.65 , pp. 11771-11778
    • Chen, Y.C.1    Giovannucci, E.2    Lazarus, R.3    Kraft, P.4    Ketkar, S.5    Hunter, D.J.6
  • 114
    • 15944377845 scopus 로고    scopus 로고
    • Sequence variants in Toll-like receptor gene cluster (TLR6-TLR1-TLR10) and prostate cancer risk
    • Sun J, Wiklund F, Zheng SL, Chang B, Bälter K, Li L et al. Sequence variants in Toll-like receptor gene cluster (TLR6-TLR1-TLR10) and prostate cancer risk. J Nat Cancer Inst 2005; 97: 525-532.
    • (2005) J Nat Cancer Inst , vol.97 , pp. 525-532
    • Sun, J.1    Wiklund, F.2    Zheng, S.L.3    Chang, B.4    Bälter, K.5    Li, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.