Connective tissue growth factor is responsible for transforming growth factor-beta-induced peritoneal mesothelial cell apoptosis

Nephron - Experimental Nephrology

Volumn 103, Issue 4, 2006, Pages

  Szeto, Cheuk Chun ^a   Chow, Kai Ming ^a   Lai, Ka Bik ^a   Szeto, Carol Yi Ki ^a   Kwan, Bonnie Ching Ha ^a   Li, Philip Kam Tao ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Cytokine; Peritoneal dialysis; RNA interference

Indexed keywords

ANTIBODY; CONNECTIVE TISSUE GROWTH FACTOR; PROTEIN BAX; PROTEIN BCL 2; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEATH; CONTROLLED STUDY; DOWN REGULATION; FLOW CYTOMETRY; GENE EXPRESSION; GENE SILENCING; INCIDENCE; MESOTHELIUM CELL; NONHUMAN; PERITONEUM CELL; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; DOWN-REGULATION; EPITHELIAL CELLS; FIBROSIS; IMMEDIATE-EARLY PROTEINS; INFLAMMATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; PERITONEUM; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; RNA INTERFERENCE; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 33746350745     PISSN: 16602129     EISSN: None     Source Type: Journal    
DOI: 10.1159/000092907     Document Type: Article

References (34)

1. Kawaguchi Y, Hasegawa T, Nakayama M, Kubo H, Shigematu T: Issues affecting the longevity of the continuous peritoneal dialysis therapy. Kidney Int Suppl 1997;62:S105-107.
2. Nagy J: Peritoneal membrane morphology and function. Kidney Int Suppl 1996;56:S2-S11.
3. Margetts PJ, Kolb M, Galt T, Hoff CM, Shockley TR, Gauldie J: Gene transfer of transforming growth factor-beta1 to the rat peritoneum: effects on membrane function. J Am Soc Nephrol 2001;12:2029-2039.
4. Margetts PJ, Bonniaud P: Basic mechanisms and clinical implications of peritoneal fibrosis. Perit Dial Int 2003;23:530-541.
5. Szeto CC, Lai KB, Chow KM, Szeto CY, Wong TY, Li PK: Differential effects of transforming growth factor-beta on the synthesis of connective tissue growth factor and vascular endothelial growth factor by peritoneal mesothelial cell. Nephron Exp Nephrol 2005;99:95-104.
6. Leard LE, Broaddus VC: Mesothelial cell proliferation and apoptosis. Respirology 2004;9:292-299.
7. Boulanger E, Wautier MP, Gane P, Mariette C, Devuyst O, Wautier JL: The triggering of human peritoneal mesothelial cell apoptosis and oncosis by glucose and glycoxidation products. Nephrol Dial Transplant 2004;19:2208-2216.
8. Alscher DM, Biegger D, Mettang T, van der Kuip H, Kuhlmann U, Fritz P: Apoptosis of mesothelial cells caused by unphysiological characteristics of peritoneal dialysis fluids. Artif Organs 2003;27:1035-1040.
9. Amore A, Cappelli G, Cirina P, Conti G, Gambaruto C, Silvestro L, Coppo R: Glucose degradation products increase apoptosis of human mesothelial cells. Nephrol Dial Transplant 2003;18:677-688.
10. Brown TL, Patil S, Howe PH: Analysis of TGF-beta-inducible apoptosis. Methods Mol Biol 2000;142:149-167.
11. Schuster N, Krieglstein K: Mechanisms of TGF-beta-mediated apoptosis. Cell Tissue Res 2002;307:1-14.
12. Bottinger EP, Bitzer M: TGF-beta signaling in renal disease. J Am Soc Nephrol 2002;13:2600-2610.
13. Shima Y, Nakao K, Nakashima T, Kawakami A, Nakata K, Hamasaki K, Kato Y, Eguchi K, Ishii N: Activation of caspase-8 in transforming growth factor-beta-induced apoptosis of human hepatoma cells. Hepatology 1999;30:1215-1222.
14. Chalaux E, Lopez-Rovira T, Rosa JL, Pons G, Boxer LM, Bartrons R, Ventura F: A zinc-finger transcription factor induced by TGF-beta promotes apoptotic cell death in epithelial Mv1Lu cells. FEBS Lett 1999;457:478-482.
15. Gupta S, Clarkson MR, Duggan J, Brady HR: Connective tissue growth factor: potential role in glomerulosclerosis and tubulointerstitial fibrosis. Kidney Int 2000;58:1389-1399.
16. Hishikawa K, Oemar BS, Tanner FC, Nakaki T, Fujii T, Luscher TF: Overexpression of connective tissue growth factor gene induces apoptosis in human aortic smooth muscle cells. Circulation 1999;100:2108-2112.
17. Hishikawa K, Oemar BS, Tanner FC, Nakaki T, Luscher TF, Fujii T: Connective tissue growth factor induces apoptosis in human breast cancer cell line MCF-7. J Biol Chem 1999;274:37461-37466.
18. Hishikawa K, Nakaki T, Fujii T: Connective tissue growth factor induces apoptosis via caspase 3 in cultured human aortic smooth muscle cells. Eur J Pharmacol 2000;392:19-22.
19. Hishikawa K, Nakaki T, Fujii T: Transforming growth factor-beta(1) induces apoptosis via connective tissue growth factor in human aortic smooth muscle cells. Eur J Pharmacol 1999;385:287-290.
20. Coyle B, Freathy C, Gant TW, Roberts RA, Cain K: Characterization of the transforming growth factor-beta 1-induced apoptotic transcriptome in FaO hepatoma cells. J Biol Chem 2003;278:5920-5928.
21. Akiba T, Ota T, Fushimi K, Shimamura H, Tamura H, Sasaki S, Marumo F: Water channel AQP-1 in the primary cell culture of rat peritoneum. Adv Perit Dial 1999;15:3-6.
22. Offner FA, Feichtinger H, Stadimann S, Obrist P, Marth C, Klingler P, Grage B, Schmahl M, Knabbe C: Transforming growth factor-beta synthesis by human peritoneal mesothelial cells. Induction by interleukin-1. Am J Pathol 1996;148:1679-1688.
23. Lai KN, Lai KB, Szeto CC, Lam CW, Leung JC: Growth factors in continuous ambulatory peritoneal dialysis effluent: relation with peritoneal transport of small solutes. Am J Nephrol 1999;19:416-422.
24. Lin CY, Chen WP, Yang LY, Chen A, Huang TP: Persistent transforming growth factor-beta 1 expression may predict peritoneal fibrosis in CAPD patients with frequent peritonitis occurrence. Am J Nephrol 1998;18:513-519.
25. Yanez-Mo M, Lara-Pezzi E, Selgas R, Ramirez-Huesca M, Dominguez-Jimenez C, Jimenez-Heffernan JA, Aguilera A, Sanchez-Tomero JA, Bajo MA, Alvarez V, Castro MA, del Peso G, Cirujeda A, Gamallo C, Sanchez-Madrid F, Lopez-Cabrera M: Peritoneal dialysis and epithelial-to-mesenchymal transition of mesothelial cells. N Engl J Med 2003;348:403-413.
26. Musi B, Braide M, Carlsson O, Wieslander A, Albrektsson A, Ketteier M, Westenfeld R, Floege J, Rippe B: Biocompatibility of peritoneal dialysis fluids: long-term exposure of non-uremic rats. Perit Dial Int 2004;24:37-47.
27. Kang DH, Hong YS, Lim HJ, Choi JH, Han DS, Yoon KI: High glucose solution and spent dialysate stimulate the synthesis of transforming growth factor-beta 1 of human peritoneal mesothelial cells: effect of cytokine costimulation. Perit Dial Int 1999;19:221-230.
28. Wong TY, Szeto CC, Lai KB, Lam CW, Lai KN, Li PK: Longitudinal study of peritoneal membrane function in CAPD: relationship with peritonitis and fibrosing factors. Perit Dial Int 2000;20:679-686.
29. Lai KN, Lai KB, Szeto CC, Lam CW, Leung JC: Growth factors in continuous ambulatory peritoneal dialysis effluent: their relation with peritoneal transport of small solutes. Am J Nephrol 1999;19:416-422.
30. Grotendorst GR: Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts. Cytokine Growth Factor Rev 1997;8:171-179.
31. Grotendorst GR, Okochi H, Hayashi N: A novel transforming growth factor beta response element controls the expression of the connective tissue growth factor gene. Cell Growth Differ 1996;7:469-480.
32. Chen MM, Lam A, Abraham JA, et al: CTGF expression is induced by TGF- beta in cardiac fibroblasts and cardiac myocytes: a potential role in heart fibrosis. J Mol Cell Cardiol 2000;32:1805-1819.
33. Zarrinkalam KH, Stanley JM, Gray J, Oliver N, Faull RJ: Connective tissue growth factor and its regulation in the peritoneal cavity of peritoneal dialysis patients. Kidney Int 2003;64:331-338.
34. Stevenson M: Therapeutic potential of RNA interference. N Engl J Med 2004;351:1772-1777.