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Volumn 82, Issue 3, 2007, Pages 465-476

Pivotal Advance: Slit-2/Robo-1 modulates the CXCL12/CXCR4-induced chemotaxis of T cells

Author keywords

Chemokine; Inflammation; Leukocytes; Migration; Signal transduction

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PROTEIN KINASE B; PROTEIN KINASE LCK; PROTEIN TYROSINE KINASE; ROUNDABOUT RECEPTOR; SLIT2 PROTEIN; STROMAL CELL DERIVED FACTOR 1; ALPHA CHEMOKINE; IMMUNOGLOBULIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; NERVE PROTEIN; PROTEIN CDC42; SIGNAL PEPTIDE; SLIT HOMOLOG 2 PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 34548407427     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.1106678     Document Type: Article
Times cited : (92)

References (62)
  • 1
    • 0033582914 scopus 로고    scopus 로고
    • Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance
    • Brose, K., Bland, K. S., Wang, K. H., Arnott, D., Henzel, W., Goodman, C. S., Tessier-Lavigne, M., Kidd, T. (1999) Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance. Cell 96, 795-806.
    • (1999) Cell , vol.96 , pp. 795-806
    • Brose, K.1    Bland, K.S.2    Wang, K.H.3    Arnott, D.4    Henzel, W.5    Goodman, C.S.6    Tessier-Lavigne, M.7    Kidd, T.8
  • 2
    • 0033582907 scopus 로고    scopus 로고
    • Slit is the midline repellent for the Robo receptor in Drosophila
    • Kidd, T., Bland, K. S., Goodman, C. S. (1999) Slit is the midline repellent for the Robo receptor in Drosophila. Cell 96, 785-794.
    • (1999) Cell , vol.96 , pp. 785-794
    • Kidd, T.1    Bland, K.S.2    Goodman, C.S.3
  • 3
    • 0033953450 scopus 로고    scopus 로고
    • Embryonic expression and extracellular secretion of Xenopus slit
    • Chen, J. H., Wu, W., Li, H. S., Fagaly, T., Zhou, L., Wu, J. Y., Rao, Y. (2000) Embryonic expression and extracellular secretion of Xenopus slit. Neuroscience 96, 231-236.
    • (2000) Neuroscience , vol.96 , pp. 231-236
    • Chen, J.H.1    Wu, W.2    Li, H.S.3    Fagaly, T.4    Zhou, L.5    Wu, J.Y.6    Rao, Y.7
  • 5
    • 0034213443 scopus 로고    scopus 로고
    • Expression of the vertebrate Slit gene family and their putative receptors, the Robo genes, in the developing murine kidney
    • Piper, M., Georgas, K., Yamada, T., Little, M. (2000) Expression of the vertebrate Slit gene family and their putative receptors, the Robo genes, in the developing murine kidney. Mech. Dev. 94, 213-217.
    • (2000) Mech. Dev , vol.94 , pp. 213-217
    • Piper, M.1    Georgas, K.2    Yamada, T.3    Little, M.4
  • 6
    • 0035831296 scopus 로고    scopus 로고
    • Hierarchical organization of guidance receptors: Silencing of netrin attraction by slit through a Robo/DCC receptor complex
    • Stein, E., Tessier-Lavigne, M. (2001) Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complex. Science 291, 1928-1938.
    • (2001) Science , vol.291 , pp. 1928-1938
    • Stein, E.1    Tessier-Lavigne, M.2
  • 7
    • 0036777901 scopus 로고    scopus 로고
    • Slit proteins: Molecular guidance cues for cells ranging from neurons to leukocytes
    • Wong, K., Park, H. T., Wu, J. Y., Rao, Y. (2002) Slit proteins: molecular guidance cues for cells ranging from neurons to leukocytes. Curr. Opin. Genet. Dev. 12, 583-591.
    • (2002) Curr. Opin. Genet. Dev , vol.12 , pp. 583-591
    • Wong, K.1    Park, H.T.2    Wu, J.Y.3    Rao, Y.4
  • 8
    • 0033603247 scopus 로고    scopus 로고
    • Chimeric axon guidance receptors: The cytoplasmic domains of slit and netrin receptors specify attraction versus repulsion
    • Bashaw, G. J., Goodman, C. S. (1999) Chimeric axon guidance receptors: the cytoplasmic domains of slit and netrin receptors specify attraction versus repulsion. Cell 97, 917-926.
    • (1999) Cell , vol.97 , pp. 917-926
    • Bashaw, G.J.1    Goodman, C.S.2
  • 9
    • 0033595192 scopus 로고    scopus 로고
    • Directional guidance of neuronal migration in the olfactory system by the protein Slit
    • Wu, W., Wong, K., Chen, J., Jiang, Z., Dupuis, S., Wu, J. Y., Rao, Y. (1999) Directional guidance of neuronal migration in the olfactory system by the protein Slit. Nature 400, 331-336.
    • (1999) Nature , vol.400 , pp. 331-336
    • Wu, W.1    Wong, K.2    Chen, J.3    Jiang, Z.4    Dupuis, S.5    Wu, J.Y.6    Rao, Y.7
  • 10
    • 18744438104 scopus 로고    scopus 로고
    • Slit: A roadblock for chemotaxis
    • Fernandis, A. Z., Ganju, R. K. (2001) Slit: a roadblock for chemotaxis. Sci. STKE 2001, PE1.
    • (2001) Sci. STKE , vol.2001
    • Fernandis, A.Z.1    Ganju, R.K.2
  • 11
    • 0035282797 scopus 로고    scopus 로고
    • The N-terminal leucine-rich regions in Slit are sufficient to repel olfactory bulb axons and subventricular zone neurons
    • Chen, J. H., Wen, L., Dupuis, S., Wu, J. Y., Rao, Y. (2001) The N-terminal leucine-rich regions in Slit are sufficient to repel olfactory bulb axons and subventricular zone neurons. J. Neurosci. 21, 1548-1556.
    • (2001) J. Neurosci , vol.21 , pp. 1548-1556
    • Chen, J.H.1    Wen, L.2    Dupuis, S.3    Wu, J.Y.4    Rao, Y.5
  • 12
    • 0036013772 scopus 로고    scopus 로고
    • GAPs in Slit-Robo signaling
    • Ghose, A., Van Vactor, D. (2002) GAPs in Slit-Robo signaling. Bioessays 24, 401-404.
    • (2002) Bioessays , vol.24 , pp. 401-404
    • Ghose, A.1    Van Vactor, D.2
  • 13
    • 0032416836 scopus 로고    scopus 로고
    • Distinct but overlapping expression patterns of two vertebrate slit homologs implies functional roles in CNS development and organogenesis
    • Holmes, G. P., Negus, K., Burridge, L., Raman, S., Algar, E., Yamada, T., Little, M. H. (1998) Distinct but overlapping expression patterns of two vertebrate slit homologs implies functional roles in CNS development and organogenesis. Mech. Dev. 79, 57-72.
    • (1998) Mech. Dev , vol.79 , pp. 57-72
    • Holmes, G.P.1    Negus, K.2    Burridge, L.3    Raman, S.4    Algar, E.5    Yamada, T.6    Little, M.H.7
  • 14
    • 0032570050 scopus 로고    scopus 로고
    • Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system
    • Itoh, A., Miyabayashi, T., Ohno, M., Sakano, S. (1998) Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system. Brain Res. Mol. Brain Res. 62, 175-186.
    • (1998) Brain Res. Mol. Brain Res , vol.62 , pp. 175-186
    • Itoh, A.1    Miyabayashi, T.2    Ohno, M.3    Sakano, S.4
  • 15
    • 0033566579 scopus 로고    scopus 로고
    • The mouse SLIT family: Secreted ligands for ROBO expressed in patterns that suggest a role in morphogenesis and axon guidance
    • Yuan, W., Zhou, L., Chen, J. H., Wu, J. Y., Rao, Y., Ornitz, D. M. (1999) The mouse SLIT family: secreted ligands for ROBO expressed in patterns that suggest a role in morphogenesis and axon guidance. Dev. Biol. 212, 290-306.
    • (1999) Dev. Biol , vol.212 , pp. 290-306
    • Yuan, W.1    Zhou, L.2    Chen, J.H.3    Wu, J.Y.4    Rao, Y.5    Ornitz, D.M.6
  • 16
    • 0032559219 scopus 로고    scopus 로고
    • Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors
    • Kidd, T., Brose, K., Mitchell, K. J., Fetter, R. D., Tessier-Lavigne, M., Goodman, C. S., Tear, G. (1998) Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors. Cell 92, 205-215.
    • (1998) Cell , vol.92 , pp. 205-215
    • Kidd, T.1    Brose, K.2    Mitchell, K.J.3    Fetter, R.D.4    Tessier-Lavigne, M.5    Goodman, C.S.6    Tear, G.7
  • 17
    • 0034705292 scopus 로고    scopus 로고
    • Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor
    • Bashaw, G. J., Kidd, T., Murray, D., Pawson, T., Goodman, C. S. (2000) Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor. Cell 101, 703-715.
    • (2000) Cell , vol.101 , pp. 703-715
    • Bashaw, G.J.1    Kidd, T.2    Murray, D.3    Pawson, T.4    Goodman, C.S.5
  • 18
    • 0027481755 scopus 로고
    • Mutations affecting growth cone guidance in Drosophila: Genes necessary for guidance toward or away from the midline
    • Seeger, M., Tear, G., Ferres-Marco, D., Goodman, C. S. (1993) Mutations affecting growth cone guidance in Drosophila: genes necessary for guidance toward or away from the midline. Neuron 10, 409-426.
    • (1993) Neuron , vol.10 , pp. 409-426
    • Seeger, M.1    Tear, G.2    Ferres-Marco, D.3    Goodman, C.S.4
  • 19
    • 0036800124 scopus 로고    scopus 로고
    • Activation of the repulsive receptor Roundabout inhibits N-cadherin-mediated cell adhesion
    • Rhee, J., Mahfooz, N. S., Arregui, C., Lilien, J., Balsamo, J., VanBerkum, M. F. (2002) Activation of the repulsive receptor Roundabout inhibits N-cadherin-mediated cell adhesion. Nat. Cell Biol. 4, 798-805.
    • (2002) Nat. Cell Biol , vol.4 , pp. 798-805
    • Rhee, J.1    Mahfooz, N.S.2    Arregui, C.3    Lilien, J.4    Balsamo, J.5    VanBerkum, M.F.6
  • 20
  • 21
    • 19044369900 scopus 로고    scopus 로고
    • Axon guidance: Growth cones make an unexpected turn
    • Dickson, B. J., Senti, K. A. (2002) Axon guidance: growth cones make an unexpected turn. Curr. Biol. 12, R218-R220.
    • (2002) Curr. Biol , vol.12
    • Dickson, B.J.1    Senti, K.A.2
  • 22
    • 0033578070 scopus 로고    scopus 로고
    • Axon guidance: Starting and stopping with slit
    • Guthrie, S. (1999) Axon guidance: starting and stopping with slit. Curr. Biol. 9, R432-R435.
    • (1999) Curr. Biol , vol.9
    • Guthrie, S.1
  • 24
    • 0035909966 scopus 로고    scopus 로고
    • Inadequate lung development and bronchial hyperplasia in mice with a targeted deletion in the Dutt1/Robo1 gene
    • Xian, J., Clark, K. J., Fordham, R., Pannell, R., Rabbitts, T. H., Rabbitts, P. H. (2001) Inadequate lung development and bronchial hyperplasia in mice with a targeted deletion in the Dutt1/Robo1 gene. Proc. Natl. Acad. Sci. USA 98, 15062-15066.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 15062-15066
    • Xian, J.1    Clark, K.J.2    Fordham, R.3    Pannell, R.4    Rabbitts, T.H.5    Rabbitts, P.H.6
  • 27
    • 0043170818 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of the SLIT2 gene in gliomas
    • Dallol, A., Krex, D., Hesson, L., Eng, C., Maher, E. R., Latif, F. (2003) Frequent epigenetic inactivation of the SLIT2 gene in gliomas. Oncogene 22, 4611-4616.
    • (2003) Oncogene , vol.22 , pp. 4611-4616
    • Dallol, A.1    Krex, D.2    Hesson, L.3    Eng, C.4    Maher, E.R.5    Latif, F.6
  • 29
    • 1542365170 scopus 로고    scopus 로고
    • Slit protein-mediated inhibition of CXCR4-induced chemotactic and chemoinvasive signaling pathways in breast cancer cells
    • Prasad, A., Fernandis, A. Z., Rao, Y., Ganju, R. K. (2004) Slit protein-mediated inhibition of CXCR4-induced chemotactic and chemoinvasive signaling pathways in breast cancer cells. J. Biol. Chem. 279, 9115-9124.
    • (2004) J. Biol. Chem , vol.279 , pp. 9115-9124
    • Prasad, A.1    Fernandis, A.Z.2    Rao, Y.3    Ganju, R.K.4
  • 31
    • 0036954119 scopus 로고    scopus 로고
    • Slit proteins, potential endogenous modulators of inflammation
    • Havlioglu, N., Yuan, L., Tang, H., Wu, J. Y. (2002) Slit proteins, potential endogenous modulators of inflammation. J. Neurovirol. 8, 486-495.
    • (2002) J. Neurovirol , vol.8 , pp. 486-495
    • Havlioglu, N.1    Yuan, L.2    Tang, H.3    Wu, J.Y.4
  • 35
    • 10744224816 scopus 로고    scopus 로고
    • Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity
    • Wang, B., Xiao, Y., Ding, B. B., Zhang, N., Yuan, X., Gui, L., Qian, K. X., Duan, S., Chen, Z., Rao, Y., Geng, J. G. (2003) Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity. Cancer Cell 4, 19-29.
    • (2003) Cancer Cell , vol.4 , pp. 19-29
    • Wang, B.1    Xiao, Y.2    Ding, B.B.3    Zhang, N.4    Yuan, X.5    Gui, L.6    Qian, K.X.7    Duan, S.8    Chen, Z.9    Rao, Y.10    Geng, J.G.11
  • 39
    • 0032507962 scopus 로고    scopus 로고
    • Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development
    • Zou, Y. R., Kottmann, A. H., Kuroda, M., Taniuchi, I., Littman, D. R. (1998) Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 393, 595-599.
    • (1998) Nature , vol.393 , pp. 595-599
    • Zou, Y.R.1    Kottmann, A.H.2    Kuroda, M.3    Taniuchi, I.4    Littman, D.R.5
  • 41
    • 0034235930 scopus 로고    scopus 로고
    • Critical involvement of the chemotactic axis CXCR4/stromal cell-derived factor-1 in the inflammatory component of allergic airway disease
    • Gonzalo, J. A., Lloyd, C. M., Peled, A., Delaney, T., Coyle, A. J., Gutierrez-Ramos, J. C. (2000) Critical involvement of the chemotactic axis CXCR4/stromal cell-derived factor-1 in the inflammatory component of allergic airway disease. J. Immunol. 165, 499-508.
    • (2000) J. Immunol , vol.165 , pp. 499-508
    • Gonzalo, J.A.1    Lloyd, C.M.2    Peled, A.3    Delaney, T.4    Coyle, A.J.5    Gutierrez-Ramos, J.C.6
  • 42
    • 0742325043 scopus 로고    scopus 로고
    • The CCR5 and CXCR4 coreceptors- central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection
    • Moore, J. P., Kitchen, S. G., Pugach, P., Zack, J. A. (2004) The CCR5 and CXCR4 coreceptors- central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection. AIDS Res. Hum. Retroviruses 20, 111-126.
    • (2004) AIDS Res. Hum. Retroviruses , vol.20 , pp. 111-126
    • Moore, J.P.1    Kitchen, S.G.2    Pugach, P.3    Zack, J.A.4
  • 43
    • 0034568757 scopus 로고    scopus 로고
    • Roles of chemokines and chemokine receptors in HIV-1 infection
    • Murakami, T., Yamamoto, N. (2000) Roles of chemokines and chemokine receptors in HIV-1 infection. Int. J. Hematol. 72, 412-417.
    • (2000) Int. J. Hematol , vol.72 , pp. 412-417
    • Murakami, T.1    Yamamoto, N.2
  • 44
    • 23844513413 scopus 로고    scopus 로고
    • Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: Pivotal role of the SDF-1-CXCR4 axis
    • Kucia, M., Reca, R., Miekus, K., Wanzeck, J., Wojakowski, W., Janowska-Wieczorek, A., Ratajczak, J., Ratajczak, M. Z. (2005) Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis. Stem Cells 23, 879-894.
    • (2005) Stem Cells , vol.23 , pp. 879-894
    • Kucia, M.1    Reca, R.2    Miekus, K.3    Wanzeck, J.4    Wojakowski, W.5    Janowska-Wieczorek, A.6    Ratajczak, J.7    Ratajczak, M.Z.8
  • 46
    • 31344466955 scopus 로고    scopus 로고
    • Chemokines induce matrix metalloproteinase-2 through activation of epidermal growth factor receptor in arterial smooth muscle cells
    • Kodali, R., Hajjou, M., Berman, A. B., Bansal, M. B., Zhang, S., Pan, J. J., Schecter, A. D. (2006) Chemokines induce matrix metalloproteinase-2 through activation of epidermal growth factor receptor in arterial smooth muscle cells. Cardiovasc. Res. 69, 706-715.
    • (2006) Cardiovasc. Res , vol.69 , pp. 706-715
    • Kodali, R.1    Hajjou, M.2    Berman, A.B.3    Bansal, M.B.4    Zhang, S.5    Pan, J.J.6    Schecter, A.D.7
  • 47
    • 23844452417 scopus 로고    scopus 로고
    • The therapeutic potential in targeting CCR5 and CXCR4 receptors in infectious and allergic pulmonary disease
    • Hogaboam, C. M., Carpenter, K. J., Schuh, J. M., Proudfoot, A. A., Bridger, G., Buckland, K. F. (2005) The therapeutic potential in targeting CCR5 and CXCR4 receptors in infectious and allergic pulmonary disease. Pharmacol. Ther. 107, 314-328.
    • (2005) Pharmacol. Ther , vol.107 , pp. 314-328
    • Hogaboam, C.M.1    Carpenter, K.J.2    Schuh, J.M.3    Proudfoot, A.A.4    Bridger, G.5    Buckland, K.F.6
  • 49
    • 0035284742 scopus 로고    scopus 로고
    • Stromal cell-derived factor 1 α-induced chemotaxis in T cells is mediated by nitric oxide signaling pathways
    • Cherla, R. P., Ganju, R. K. (2001) Stromal cell-derived factor 1 α-induced chemotaxis in T cells is mediated by nitric oxide signaling pathways. J. Immunol. 166, 3067-3074.
    • (2001) J. Immunol , vol.166 , pp. 3067-3074
    • Cherla, R.P.1    Ganju, R.K.2
  • 50
    • 0038526242 scopus 로고    scopus 로고
    • Differential regulation of CXCR4-mediated T-cell chemotaxis and mitogen-activated protein kinase activation by the membrane tyrosine phosphatase, CD45
    • Fernandis, A. Z., Cherla, R. P., Ganju, R. K. (2003) Differential regulation of CXCR4-mediated T-cell chemotaxis and mitogen-activated protein kinase activation by the membrane tyrosine phosphatase, CD45. J. Biol. Chem. 278, 9536-9543.
    • (2003) J. Biol. Chem , vol.278 , pp. 9536-9543
    • Fernandis, A.Z.1    Cherla, R.P.2    Ganju, R.K.3
  • 51
    • 0032483419 scopus 로고    scopus 로고
    • The α-chemokine, stromal cell-derived factor-1α, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways
    • Ganju, R. K., Brubaker, S. A., Meyer, J., Dutt, P., Yang, Y., Qin, S., Newman, W., Groopman, J. E. (1998) The α-chemokine, stromal cell-derived factor-1α, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways. J. Biol. Chem. 273, 23169-23175.
    • (1998) J. Biol. Chem , vol.273 , pp. 23169-23175
    • Ganju, R.K.1    Brubaker, S.A.2    Meyer, J.3    Dutt, P.4    Yang, Y.5    Qin, S.6    Newman, W.7    Groopman, J.E.8
  • 52
    • 0033527738 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus-encoded G protein-coupled receptor activation of c-jun amino-terminal kinase/stress-activated protein kinase and lyn kinase is mediated by related adhesion focal tyrosine kinase/proline-rich tyrosine kinase 2
    • Munshi, N., Ganju, R. K., Avraham, S., Mesri, E. A., Groopman, J. E. (1999) Kaposi's sarcoma-associated herpesvirus-encoded G protein-coupled receptor activation of c-jun amino-terminal kinase/stress-activated protein kinase and lyn kinase is mediated by related adhesion focal tyrosine kinase/proline-rich tyrosine kinase 2. J. Biol. Chem. 274, 31863-31867.
    • (1999) J. Biol. Chem , vol.274 , pp. 31863-31867
    • Munshi, N.1    Ganju, R.K.2    Avraham, S.3    Mesri, E.A.4    Groopman, J.E.5
  • 54
    • 0035242032 scopus 로고    scopus 로고
    • SHP2 and cbl participate in α-chemokine receptor CXCR4-mediated signaling pathways
    • Chernock, R. D., Cherla, R. P., Ganju, R. K. (2001) SHP2 and cbl participate in α-chemokine receptor CXCR4-mediated signaling pathways. Blood 97, 608-615.
    • (2001) Blood , vol.97 , pp. 608-615
    • Chernock, R.D.1    Cherla, R.P.2    Ganju, R.K.3
  • 55
    • 0037097588 scopus 로고    scopus 로고
    • Lck is required for stromal cell-derived factor 1 α (CXCL12)-induced lymphoid cell chemotaxis
    • Inngjerdingen, M., Torgersen, K. M., Maghazachi, A. A. (2002) Lck is required for stromal cell-derived factor 1 α (CXCL12)-induced lymphoid cell chemotaxis. Blood 99, 4318-4325.
    • (2002) Blood , vol.99 , pp. 4318-4325
    • Inngjerdingen, M.1    Torgersen, K.M.2    Maghazachi, A.A.3
  • 56
    • 11244275367 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1α/CXCL12-induced chemotaxis of T cells involves activation of the Ras-GAP-associated docking protein p62Dok-1
    • Okabe, S., Fukuda, S., Kim, Y. J., Niki, M., Pelus, L. M., Ohyashiki, K., Pandolfi, P. P., Broxmeyer, H. E. (2005) Stromal cell-derived factor-1α/CXCL12-induced chemotaxis of T cells involves activation of the Ras-GAP-associated docking protein p62Dok-1. Blood 105, 474-480.
    • (2005) Blood , vol.105 , pp. 474-480
    • Okabe, S.1    Fukuda, S.2    Kim, Y.J.3    Niki, M.4    Pelus, L.M.5    Ohyashiki, K.6    Pandolfi, P.P.7    Broxmeyer, H.E.8
  • 57
    • 0034733540 scopus 로고    scopus 로고
    • Characterization of the tyrosine kinases RAFTK/Pyk2 and FAK in nerve growth factor-induced neuronal differentiation
    • Park, S. Y., Avraham, H., Avraham, S. (2000) Characterization of the tyrosine kinases RAFTK/Pyk2 and FAK in nerve growth factor-induced neuronal differentiation. J. Biol. Chem. 275, 19768-19777.
    • (2000) J. Biol. Chem , vol.275 , pp. 19768-19777
    • Park, S.Y.1    Avraham, H.2    Avraham, S.3
  • 59
    • 21244489948 scopus 로고    scopus 로고
    • Heat shock protein 60 activates cytokine-associated negative regulator suppressor of cytokine signaling 3 in T cells: Effects on signaling, chemotaxis, and inflammation
    • Zanin-Zhorov, A., Tal, G., Shivtiel, S., Cohen, M., Lapidot, T., Nussbaum, G., Marqalit, R., Cohen, I. R., Lider, O. (2005) Heat shock protein 60 activates cytokine-associated negative regulator suppressor of cytokine signaling 3 in T cells: effects on signaling, chemotaxis, and inflammation. J. Immunol. 175, 276-285.
    • (2005) J. Immunol , vol.175 , pp. 276-285
    • Zanin-Zhorov, A.1    Tal, G.2    Shivtiel, S.3    Cohen, M.4    Lapidot, T.5    Nussbaum, G.6    Marqalit, R.7    Cohen, I.R.8    Lider, O.9
  • 60
    • 0028961293 scopus 로고
    • Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
    • Nobes, C. D., Hall, A. (1995) Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 81, 53-62.
    • (1995) Cell , vol.81 , pp. 53-62
    • Nobes, C.D.1    Hall, A.2
  • 62
    • 0036142414 scopus 로고    scopus 로고
    • Stromal cell derived factor 1 activates LIM kinase 1 and induces cofilin phosphorylation for T-cell chemotaxis
    • Nishita, M., Aizawa, H., Mizumo, K. (2002) Stromal cell derived factor 1 activates LIM kinase 1 and induces cofilin phosphorylation for T-cell chemotaxis. Mol. Cell. Biol. 22, 774-783.
    • (2002) Mol. Cell. Biol , vol.22 , pp. 774-783
    • Nishita, M.1    Aizawa, H.2    Mizumo, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.