The oxidatively induced DNA lesions 8,5′-cyclo-2′-deoxyadenosine and 8-hydroxy-2′-deoxyadenosine are strongly resistant to acid-induced hydrolysis of the glycosidic bond

Mechanisms of Ageing and Development

Volumn 128, Issue 9, 2007, Pages 494-502

  Theruvathu, Jacob A ^a   Jaruga, Pawel ^b,c   Dizdaroglu, Miral ^d   Brooks, P J ^a  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^b Baltimore County   (United States)

^c NICOLAUS COPERNICUS UNIVERSITY   (Poland)

^d NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

Author keywords

DNA repair; Neurodegeneration; Oxidative stress; Xeroderma pigmentosum

Indexed keywords

8 HYDROXY 2' DEOXYADENOSINE; 8,5' CYCLO 2' DEOXYADENOSINE; ADENOSINE DERIVATIVE; DNA; GLYCOSIDE; UNCLASSIFIED DRUG;

AGING; ARTICLE; DNA DAMAGE; EXCISION REPAIR; FRAGMENTATION REACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYDROLYSIS KINETICS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FOLDING; XERODERMA PIGMENTOSUM;

AGING; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYADENOSINES; DNA DAMAGE; DNA REPAIR; FORMIC ACIDS; HUMANS; HYDROLYSIS; KINETICS; MASS SPECTROMETRY; OXIDATIVE STRESS; TEMPERATURE; XERODERMA PIGMENTOSUM;

EID: 34548403117     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2007.06.006     Document Type: Article

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