Characterization of the aldehyde reactive probe reaction with AP-sites in DNA: Influence of AP-lyase on adduct stability

Nucleosides, Nucleotides and Nucleic Acids

Volumn 25, Issue 7, 2006, Pages 823-842

  Bennett, Samuel ^a   Kitner, Joshua ^a  

^a OREGON STATE UNIVERSITY   (United States)

Author keywords

Aldehyde reactive probe; AP endonuclease; AP lyase; AP site; Oxime; Uracil DNA glycosylase

Indexed keywords

ALDEHYDE; DEOXYRIBONUCLEASE I; DNA; DNA GLYCOSYLTRANSFERASE; METHOXYAMINE; PYRIMIDINE DIMER;

APYRIMIDINIC SITE; ARTICLE; INCUBATION TIME; NONHUMAN; YEAST;

ALDEHYDES; BINDING SITES; DEOXYRIBONUCLEASE IV (PHAGE T4-INDUCED); DNA; DNA ADDUCTS; DNA DAMAGE; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; ENZYME STABILITY; MOLECULAR PROBES;

EID: 33746824232     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770600726133     Document Type: Article

References (21)

1. Lindahl, T. Instability and Decay of the Primary Structure of DNA. Nature 1993, 362, 709-715.
2. Rabow, L.; Stubbe, J.; Kozarich, J.W.; Gerlt, J.A. Identification of the Alkaline-Labile Product Accompanying Cytosine Release during Bleomycin-Mediated Degradation of d(CGCGCG). Journal of the American Chemical Society 1986, 108, 7130-7131.
3. Drinkwater, N.R.; Miller, E.C.;Miller, J.A. Estimation of Apurinic/Apyrimidinic Sites and Phosphotriesters in Deoxyribonucleic Acid Treated with Electrophilic Carcinogens And Mutagens. Biochemistry 1980, 19, 5087-5092.
4. Foster, P.L.; Davis, E.F. Loss of an Apurinic/Apyrimidinic Site Endonuclease Increases the Mutagenicity of N-Methyl-N′-Nitro-N- Nitrosoguanidine to Escherichia coli. Proceedings of the National Academy of. Sciences USA 1987, 84, 2891-2895.
5. Scholes, G.; Stein, G.; Weiss, J. Action of X-Rays on Nucleic Acids. Nature 1949, 164, 709.
6. Von Sonntag, C. The Chemical Basis of Radiation Biology. Taylor & Francis: Philadelphia, 1987.
7. Lindahl, T.; Nyberg, B. Rate of Depurination of Native Deoxyribonucleic Acid. Biochemistry 1972, 11, 3610-3618.
8. Nakamura, J.; Swenberg, J.A. Endogenous Apurinic/Apyrimidinic Sites in Genomic DNA of Mammalian Tissues. Cancer Research 1999, 59, 2522-2526.
9. Kokoska, R.J.; McCulloch, S.D.; Kunkel, T.A. The Efficiency and Specificity of Apurinic/Apyrimidinic Site Bypass by Human DNA Polymerase {eta} and Sulfolobus solfataricus Dpo4. Journal of Biological Chemistry 2003, 278, 50537-50545.
10. Yu, S.-L.; Lee, S.-K.; Johnson, R.E.; Prakash, L.; Prakash, S. The Stalling of Transcription at Abasic Sites Is Highly Mutagenic. Molecular and Cellular Biology 2003, 23, 382-388.
11. Loeb, L.A.; Preston, B.D. Mutagenesis by Apurinic/Apyrimidinic Sites. Annuual Review of Genetics 1986, 20, 201-230.
12. Manoharan, M.; Ransom, S.C.; Mazumder, A.; Gerit, J.A.; Wilde, J.A.; Withka, J.A.; Bolton, P.H. The Characterization of Abasic Sites in DNA Heteroduplexes by Site Specific Labeling with Carbon-13. Journal of the American Chemical Society 1988, 110, 1620-1622.
13. Beger, R.D.; Bolton, P.H. Structures of Apurinic and Apyrimidinic Sites in Duplex DNAs. Journal of the Biological Chemical 1998, 273, 15565-15573.
14. Coombs, M.M.; Livingston, D.C. Reaction of Apurinic Acid with Aldehyde Reagents. Biochimica et Biophysica Acta 1969, 174, 161-173.
15. 14C]Methoxyamine. A Method for the Quantitative Assay of AP Sites in DNA. Biochimica et Biophysica Acta 1983, 740, 410-416.
16. Kow, Y.W. Mechanism of Action of Escherichia coli Exonuclease III. Biochemistry 1989, 28, 3280-3287.
17. Kubo, K.; Ide, H.; Wallace, S.S.; Kow, Y.W. A novel, Sensitive, and Specific Assay for Abasic Sites, the Most Commonly Produced DNA Lesion. Biochemistry 1992, 31, 3703-3708.
18. Kow, Y.W.; Dare, A. Detection of Abasic Sites and Oxidative DNA Base Damage Using an ELISA-Like Assay. Methods 2000, 22, 164-169.
19. Nakamura, J.; Walker, V.E.; Upton, P.B.; Chiang, S.Y.; Kow, Y.W.; Swenberg, J.A. Highly Sensitive Apurinic/Apyrimidinic Site Assay can Detect Spontaneous and Chemically Induced Depurination under Physiological Conditions. Cancer Research 1998, 58, 222-225.
20. Bennett, S.E.; Sung, J.-S. Fidelity of Uracil-Initiated Base Excision DNA Repair in DNA Polymerase Beta-Proficient and -Deficient Mouse Embryonic Fibroblast Cell Extracts. Journal of Biological Chemistry 2001, 276, 42588-42600.
21. Levin, J.D.; Demple, B. Analysis of Class II (hydrolytic) and Class I (Beta-Lyase) Apurinic/Apyrimidinic Endonucleases with a Synthetic DNA Substrate. Nucleic Acids Research 1990, 18, 5069-5075.