The role of mitochondrial DNA large deletion for the development of presbycusis in Fischer 344 rats

Neurobiology of Disease

Volumn 27, Issue 3, 2007, Pages 370-377

  Yin, Shankai ^a   Yu, Zhiping ^b   Sockalingam, Ravi ^b   Bance, Manohar ^b   Sun, Genlou ^c   Wang, Jian ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b DALHOUSIE UNIVERSITY   (Canada)

^c SAINT MARY S UNIVERSITY   (Canada)

Author keywords

Fischer 344 rat; Large scale deletion; Mitochondrial DNA; Presbycusis; qRT PCR

Indexed keywords

MITOCHONDRIAL DNA;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DNA DAMAGE; GENE DELETION; HAIR CELL; HEARING LOSS; MALE; NONHUMAN; PATHOGENESIS; PRESBYACUSIS; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION;

AGING; ANIMALS; DNA, MITOCHONDRIAL; GENE DELETION; HAIR CELLS; MALE; PRESBYCUSIS; RATS; RATS, INBRED F344; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 34548253352     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2007.06.006     Document Type: Article

References (63)

1. Alam S.A., Oshima T., Suzuki M., Kawase T., Takasaka T., and Ikeda K. The expression of apoptosis-related proteins in the aged cochlea of Mongolian gerbils. Laryngoscope 111 3 (2001) 528-534
2. Bai U., Seidman M.D., Hinojosa R., and Quirk W.S. Mitochondrial DNA deletions associated with aging and possibly presbycusis: a human archival temporal bone study. Am. J. Otol. 18 4 (1997) 449-453
3. Boulet L., Karpati G., and Shoubridge E.A. Distribution and threshold expression of the tRNA(Lys) mutation in skeletal muscle of patients with myoclonic epilepsy and ragged-red fibers (MERRF). Am. J. Hum. Genet. 51 6 (1992) 1187-1200
4. Cadenas E., and Davies K.J. Mitochondrial free radical generation, oxidative stress, and aging. Free Radical Biol. Med. 29 3-4 (2000) 222-230
5. Cao Z., Wanagat J., McKiernan S.H., and Aiken J.M. Mitochondrial DNA deletion mutations are concomitant with ragged red regions of individual, aged muscle fibers: analysis by laser-capture microdissection. Nucleic Acids Res. 29 21 (2001) 4502-4508
6. Chabi B., Mousson de Camaret B., Duborjal H., Issartel J.P., and Stepien G. Quantification of mitochondrial DNA deletion, depletion, and overreplication: application to diagnosis. Clin. Chem. 49 8 (2003) 1309-1317
7. Chomyn A., Martinuzzi A., Yoneda M., Daga A., Hurko O., Johns D., Lai S.T., Nonaka I., Angelini C., and Attardi G. MELAS mutation in mtDNA binding site for transcription termination factor causes defects in protein synthesis and in respiration but no change in levels of upstream and downstream mature transcripts. Proc. Natl. Acad. Sci. U. S. A. 89 10 (1992) 4221-4225
8. Dai P., Yang W., Jiang S., Gu R., Yuan H., Han D., Guo W., and Cao J. Correlation of cochlear blood supply with mitochondrial DNA common deletion in presbyacusis. Acta Otolaryngol. 124 2 (2004) 130-136
9. Edris W., Burgett B., Stine O.C., and Filburn C.R. Detection and quantitation by competitive PCR of an age-associated increase in a 4.8-kb deletion in rat mitochondrial DNA. Mutat. Res. 316 2 (1994) 69-78
10. Eshaghian A., Vleugels R.A., Canter J.A., McDonald M.A., Stasko T., and Sligh J.E. Mitochondrial DNA deletions serve as biomarkers of aging in the skin, but are typically absent in nonmelanoma skin cancers. J. Invest. Dermatol. 126 2 (2006) 336-344
11. Ferlin T., Guironnet G., Barnoux M.C., Dumoulin R., Stepien G., and Mousson B. Detection of mitochondrial DNA deletions by a screening procedure using the polymerase chain reaction. Mol. Cell. Biochem. 174 1-2 (1997) 221-225
12. Fischel-Ghodsian N., Bykhovskaya Y., Taylor K., Kahen T., Cantor R., Ehrenman K., Smith R., and Keithley E. Temporal bone analysis of patients with presbycusis reveals high frequency of mitochondrial mutations. Hear. Res. 110 1-2 (1997) 147-154
13. Frisina D.R. Anatomical and neurochemical bases of presbycusis. In: Hof P.R., and Mobbs C.V. (Eds). Functional Neurobiology of Aging (2001), Academic Press, San Diego 531-547
14. Frisina D.R., and Rajan R. Inferior colliculus: aging and plasticity. In: Winer J., and Schreiner C. (Eds). The Inferior Colliculus (2005), Springer, New York 559-584
15. Gadaleta M.N., Rainaldi G., Lezza A.M., Milella F., Fracasso F., and Cantatore P. Mitochondrial DNA copy number and mitochondrial DNA deletion in adult and senescent rats. Mutat. Res. 275 3-6 (1992) 181-193
16. Gadaleta M.N., Cormio A., Pesce V., Lezza A.M., and Cantatore P. Aging and mitochondria. Biochimie 80 10 (1998) 863-870
17. Harman D. The aging process. Proc. Natl. Acad. Sci. U. S. A. 78 11 (1981) 7124-7128
18. Harman D. Aging: overview. Ann. N. Y. Acad. Sci. 928 (2001) 1-21
19. He L., Chinnery P.F., Durham S.E., Blakely E.L., Wardell T.M., Borthwick G.M., Taylor R.W., and Turnbull D.M. Detection and quantification of mitochondrial DNA deletions in individual cells by real-time PCR. Nucleic Acids Res. 30 14 (2002) e68
20. Holt I.J., Harding A.E., Cooper J.M., Schapira A.H., Toscano A., Clark J.B., and Morgan-Hughes J.A. Mitochondrial myopathies: clinical and biochemical features of 30 patients with major deletions of muscle mitochondrial DNA. Ann. Neurol. 26 6 (1989) 699-708
21. Iwai H., Lee S., Inaba M., Sugiura K., Tomoda K., Yamashita T., and Ikehara S. Prevention of accelerated presbycusis by bone marrow transplantation in senescence-accelerated mice. Bone Marrow Transplant. 28 4 (2001) 323-328
22. Kong W.J., Hu Y.J., Wang Q., Wang Y., Han Y.C., Cheng H.M., Kong W., and Guan M.X. The effect of the mtDNA 4834 deletion on hearing. Biochem. Biophys. Res. Commun. 344 1 (2006) 425-430
23. Lebrecht D., Kokkori A., Ketelsen U.P., Setzer B., and Walker U.A. Tissue-specific mtDNA lesions and radical-associated mitochondrial dysfunction in human hearts exposed to doxorubicin. J. Pathol. 207 4 (2005) 436-444
24. Liu J., Kong W., and Liu Z. Mitochondrial DNA large deletions associated with presbycusis. Lin Chuang Er Bi Yan Hou Ke Za Zhi 17 11 (2003) 678-680
25. McFadden S.L., Ding D., and Salvi R. Anatomical, metabolic and genetic aspects of age-related hearing loss in mice. Audiology 40 6 (2001) 313-321
26. Mohamed S.A., Hanke T., Erasmi A.W., Bechtel M.J., Scharfschwerdt M., Meissner C., Sievers H.H., and Gosslau A. Mitochondrial DNA deletions and the aging heart. Exp. Gerontol. 41 5 (2006) 508-517
27. Morris A.A., Taanman J.W., Blake J., Cooper J.M., Lake B.D., Malone M., Love S., Clayton P.T., Leonard J.V., and Schapira A.H. Liver failure associated with mitochondrial DNA depletion. J. Hepatol. 28 4 (1998) 556-563
28. Nickander K.K., Schmelzer J.D., and Low P.A. Assessment of the "common" 4.8-kb mitochondrial DNA deletion and identification of several closely related deletions in the dorsal root ganglion of aging and streptozotocin rats. J. Peripher Nerv. Syst. 7 2 (2002) 96-103
29. Nicklas J.A., Brooks E.M., Hunter T.C., Single R., and Branda R.F. Development of a quantitative PCR (TaqMan) assay for relative mitochondrial DNA copy number and the common mitochondrial DNA deletion in the rat. Environ. Mol. Mutagen 44 4 (2004) 313-320
30. Nicolino M., Ferlin T., Forest M., Godinot C., Carrier H., David M., Chatelain P., and Mousson B. Identification of a large-scale mitochondrial deoxyribonucleic acid deletion in endocrinopathies and deafness: report of two unrelated cases with diabetes mellitus and adrenal insufficiency, respectively. J. Clin. Endocrinol. Metab. 82 9 (1997) 3063-3067
31. Ozawa T. Genetic and functional changes in mitochondria associated with aging. Physiol. Rev. 77 2 (1997) 425-464
32. Pickles J.O. Mutation in mitochondrial DNA as a cause of presbyacusis. Audiol. Neuro-otol. 9 1 (2004) 23-33
33. Popelar J., Groh D., Mazelova J., and Syka J. Cochlear function in young and adult Fischer 344 rats. Hear. Res. 186 1-2 (2003) 75-84
34. Popelar J., Groh D., Pelanova J., Canlon B., and Syka J. Age-related changes in cochlear and brainstem auditory functions in Fischer 344 rats. Neurobiol. Aging 27 3 (2006) 490-500
35. Schon E.A., Rizzuto R., Moraes C.T., Nakase H., Zeviani M., and DiMauro S. A direct repeat is a hotspot for large-scale deletion of human mitochondrial DNA. Science 244 4902 (1989) 346-349
36. Sciacco M., Bonilla E., Schon E.A., DiMauro S., and Moraes C.T. Distribution of wild-type and common deletion forms of mtDNA in normal and respiration-deficient muscle fibers from patients with mitochondrial myopathy. Hum. Mol. Genet. 3 1 (1994) 13-19
37. Seidman M.D. Effects of dietary restriction and antioxidants on presbyacusis. Laryngoscope 110 5 Pt 1 (2000) 727-738
38. Seidman M.D., Bai U., Khan M.J., Murphy M.J., Quirk W.S., Castora F.L., and Hinojosa R. Association of mitochondrial DNA deletions and cochlear pathology: a molecular biologic tool. Laryngoscope 106 6 (1996) 777-783
39. Seidman M.D., Bai U., Khan M.J., and Quirk W.S. Mitochondrial DNA deletions associated with aging and presbyacusis. Arch. Otolaryngol. Head Neck Surg. 123 10 (1997) 1039-1045
40. Seidman M.D., Khan M.J., Bai U., Shirwany N., and Quirk W.S. Biologic activity of mitochondrial metabolites on aging and age-related hearing loss. Am. J. Otol. 21 2 (2000) 161-167
41. Seidman M.D., Ahmad N., and Bai U. Molecular mechanisms of age-related hearing loss. Ageing Res. Rev. 1 3 (2002) 331-343
42. Shoffner J.M., Lott M.T., Voljavec A.S., Soueidan S.A., Costigan D.A., and Wallace D.C. Spontaneous Kearns-Sayre/chronic external ophthalmoplegia plus syndrome associated with a mitochondrial DNA deletion: a slip-replication model and metabolic therapy. Proc. Natl. Acad. Sci. U. S. A. 86 20 (1989) 7952-7956
43. Spicer S.S., and Schulte B.A. Spiral ligament pathology in quiet-aged gerbils. Hear. Res. 172 1-2 (2002) 172-185
44. Spicer S.S., Salvi R.J., and Schulte B.A. Ablation of inner hair cells by carboplatin alters cells in the medial K(+) flow route and disrupts tectorial membrane. Hear. Res. 136 1-2 (1999) 139-150
45. Tang Y., Schon E.A., Wilichowski E., Vazquez-Memije M.E., Davidson E., and King M.P. Rearrangements of human mitochondrial DNA (mtDNA): new insights into the regulation of mtDNA copy number and gene expression. Mol. Biol. Cell 11 4 (2000) 1471-1485
46. Tarnowski B.I., Schmiedt R.A., Hellstrom L.I., Lee F.S., and Adams J.C. Age-related changes in cochleas of Mongolian gerbils. Hear. Res. 54 1 (1991) 123-134
47. Ueda N., Oshima T., Ikeda K., Abe K., Aoki M., and Takasaka T. Mitochondrial DNA deletion is a predisposing cause for sensorineural hearing loss. Laryngoscope 108 4 Pt 1 (1998) 580-584
48. Vazquez-Acevedo M., Coria R., Gonzalez-Astiazaran A., Medina-Crespo V., Ridaura-Sanz C., and Gonzalez-Halphen D. Characterization of a 5025 base pair mitochondrial DNA deletion in Kearns-Sayre syndrome. Biochim. Biophys. Acta 1271 2-3 (1995) 363-368
49. Vazquez-Acevedo M., Vazquez-Memije M.E., Mutchinick O.M., Morales J.J., Garcia-Ramos G., and Gonzalez-Halphen D. A case of Kearns-Sayre syndrome with the 4,977-bp common deletion associated with a novel 7,704-bp deletion. Neurol. Sci. 23 5 (2002) 247-250
50. Viberg A., and Canlon B. The guide to plotting a cochleogram. Hear. Res. 197 1-2 (2004) 1-10
51. Wallace D.C., Lott M.T., Lezza A.M., Seibel P., Voljavec A.S., and Shoffner J.M. Mitochondrial DNA mutations associated with neuromuscular diseases: analysis and diagnosis using the polymerase chain reaction. Pediatr. Res. 28 5 (1990) 525-528
52. Wang J., Ding D., and Salvi R. Carboplatin-induced early cochlear lesion in chinchillas. Hear. Res. 181 1-2 (2003) 65-72
53. Wei Y.H., and Lee H.C. Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging. Exp. Biol. Med. (Maywood) 227 9 (2002) 671-682
54. Wei Y.H., Ma Y.S., Lee H.C., Lee C.F., and Lu C.Y. Mitochondrial theory of aging matures - roles of mtDNA mutation and oxidative stress in human aging. Zhonghua Yixue Zazhi (Taipei) 64 5 (2001) 259-270
55. Willott J.F. Aging and the Auditory System: Anatomy, Physiology, and Psychophysics (1991), Singular Publishing Group, Inc., San Diego, London
56. Willott J.F., and Mortenson V. Age-related cochlear histopathology in C57BL/6J and CBA/J mice. Abstr. Assoc. Res. Otolaryngol. 14 (1991) 16
57. Willott J.F., Hnath Chisolm T., and Lister J.J. Modulation of presbycusis: current status and future directions. Audiol. Neurootol. 6 5 (2001) 231-249
58. Wu H., Du B., Wang P., Niu C., and Jin X. Effects of mtDNA deletion associated with abnormal expression in rat cochlear with presbycusis. Zhonghua Er-Bi-Yanhouke Zazhi 37 3 (2002) 191-193
59. Zettel M.L., O'Neill W.E., Trang T.T., and Frisina R.D. Early bilateral deafening prevents calretinin up-regulation in the dorsal cortex of the inferior colliculus of aged CBA/CaJ mice. Hear. Res. 158 1-2 (2001) 131-138
60. Zettel M.L., O'Neill W.E., Trang T.T., and Frisina R.D. The effects of early bilateral deafening on calretinin expression in the dorsal cochlear nucleus of aged CBA/CaJ mice. Hear. Res. 183 1-2 (2003) 57-66
61. Zhang X., Han D., Ding D., Dai P., Yang W., Jiang S., and Salvi R.J. Cochlear mitochondrial DNA 3867 bp deletion in aged mice. Chin. Med. J. (Engl.) 115 9 (2002) 1390-1393
62. Zhang X., Han D., Ding D., Dai P., Yang W., Jiang S., and Salvi R.J. Deletions are easy detectable in cochlear mitochondrial DNA of Cu/Zn superoxide dismutase gene knockout mice. Chin. Med. J. (Engl.) 115 2 (2002) 258-263
63. Zheng Y., Ikeda K., Nakamura M., and Takasaka T. Endonuclease cleavage of DNA in the aged cochlea of Mongolian gerbil. Hear. Res. 126 1-2 (1998) 11-18