Biallelic mutation of MSH2 in primary human cells is associated with sensitivity to irradiation and altered RAD51 foci kinetics

Journal of Medical Genetics

Volumn 44, Issue 8, 2007, Pages 516-520

  Barwell, J ^a   Pangon, L ^b   Hodgson, S ^a   Georgiou, A ^b   Kesterton, I ^b   Slade, T ^b   Taylor, M ^c   Payne, S J ^c   Brinkman, H ^a,g   Smythe, J ^d   Sebire, N J ^e   Solomon, E ^b   Docherty, Z ^b   Camplejohn, R ^f   Homfray, T ^a   Morris, J R ^b  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b GUY S HOSPITAL   (United Kingdom)

^c ST MARK S HOSPITAL   (United Kingdom)

^d NHS BLOOD AND TRANSPLANT   (United Kingdom)

^e GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^f ST THOMAS HOSPITAL   (United Kingdom)

^g WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BUTADIENE DIEPOXIDE; MITOMYCIN C; RAD51 PROTEIN;

ALLELE; ANIMAL CELL; ARTICLE; CASE REPORT; CELL KINETICS; CELL VIABILITY; CHROMOSOME DAMAGE; CONTROLLED STUDY; DNA CROSS LINKING; GENE MUTATION; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; MALE; MISMATCH REPAIR; MSH2 GENE; MUTATOR GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIOSENSITIVITY;

CHILD, PRESCHOOL; DNA REPAIR; FEMALE; GENOTYPE; HETEROZYGOTE DETECTION; HUMANS; LYMPHOMA, NON-HODGKIN; MALE; MUTATION; MUTS HOMOLOG 2 PROTEIN; NEOPLASMS; NUCLEAR FAMILY; PEDIGREE; POLYMORPHISM, SINGLE NUCLEOTIDE; RAD51 RECOMBINASE; RADIATION TOLERANCE; RECOMBINATION, GENETIC;

ANIMALIA; MURINAE;

EID: 34548222124     PISSN: 00222593     EISSN: None     Source Type: Journal    
DOI: 10.1136/jmg.2006.048660     Document Type: Article

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