Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas

Development

Volumn 134, Issue 15, 2007, Pages 2719-2725

  Strom, Alessandra ^a   Bonal, Claire ^a   Ashery Padan, Ruth ^b   Hashimoto, Naoko ^f   Campos, M Luisa ^d   Trumpp, Andreas ^e,g   Noda, Tetsuo ^c   Kido, Yoshiaki ^f   Real, Francisco X ^d   Thorel, Fabrizio ^a   Herrera, Pedro L ^a  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^b TEL AVIV UNIVERSITY   (Israel)

^c CANCER INSTITUTE   (Japan)

^d UNIVERSITAT POMPEU FABRA   (Spain)

^e SWISS INST FOR EXP CANCER RESEARCH   (Switzerland)

^f Department of Clinical Molecular Medicine ^*  (Japan)

^g EPFL   (Switzerland)

Author keywords

catenin; Apc; c myc; Growth; ICAT; Mouse; Pancreas

Indexed keywords

APC PROTEIN; AXIN; AXIN 2; BETA CATENIN; CYCLIN D2; CYCLIN DEPENDENT KINASE 4; MYC PROTEIN; PROTEIN C JUN; PROTEIN P21; T CELL FACTOR 4 PROTEIN; T CELL FACTOR PROTEIN; UNCLASSIFIED DRUG; UVOMORULIN;

ACINAR CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CELL GROWTH; CELL SPECIFICITY; COLON MUCOSA; CONTROLLED STUDY; FETUS; GENE EXPRESSION PROFILING; GROWTH REGULATION; HOMEOSTASIS; KIDNEY PARENCHYMA; LIVER PARENCHYMA; MOUSE; NONHUMAN; ONCOGENE C MYC; PANCREAS ISLET CELL HYPERPLASIA; PANCREAS TUMOR; PATHOPHYSIOLOGY; PENETRANCE; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; PROTEIN SYNTHESIS REGULATION;

ANIMALS; BETA CATENIN; GENES, APC; GENES, MYC; GENES, TUMOR SUPPRESSOR; GROWTH; HYPERPLASIA; HYPERTROPHY; MICE; MICE, TRANSGENIC; ORGAN SPECIFICITY; PANCREAS; PANCREATIC NEOPLASMS; SIGNAL TRANSDUCTION;

MUS;

EID: 34548167006     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.02875     Document Type: Article

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