The role of leukocytes bearing Natural Killer Complex receptors and Killer Immunoglobulin-like Receptors in the immunology of malaria

Current Opinion in Immunology

Volumn 19, Issue 4, 2007, Pages 416-423

  Hansen, Diana S ^a   D'Ombrain, Marthe C ^a   Schofield, Louis ^a  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROCYTE MEMBRANE PROTEIN 1; GENE PRODUCT; GLYCOSYLPHOSPHATIDYLINOSITOL; KILLER IMMUNOGLOBULIN LIKE RECEPTOR; LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NATURAL KILLER CELL RECEPTOR; UNCLASSIFIED DRUG;

ACCESSORY CELL; ADAPTIVE IMMUNITY; CYTOTOXICITY; DISEASE MODEL; DISEASE PREDISPOSITION; DISEASE RESISTANCE; DISEASE SEVERITY; ERYTHROCYTE; GENE CONTROL; HLA SYSTEM; HUMAN; IMMUNOGENETICS; IMMUNOLOGY; IMMUNOPATHOLOGY; IN VITRO STUDY; INNATE IMMUNITY; LEUKOCYTE; LEUKOCYTE ACTIVATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MALARIA; NATURAL KILLER CELL; NONHUMAN; PLASMODIUM FALCIPARUM; REVIEW; RODENT; T LYMPHOCYTE;

ANIMALS; CYTOKINES; HLA ANTIGENS; HUMANS; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; MALARIA; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; RECEPTORS, IMMUNOLOGIC; T-LYMPHOCYTE SUBSETS;

EID: 34548137267     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coi.2007.07.011     Document Type: Review

References (57)

1. Yokoyama W.M., and Plougastel B.F. Immune functions encoded by the natural killer gene complex. Nat Rev Immunol 3 (2003) 304-316
2. Moretta L., and Moretta A. Killer immunoglobulin-like receptors. Curr Opin Immunol 16 (2004) 626-633
3. McQueen K.L., and Parham P. Variable receptors controlling activation and inhibition of NK cells. Curr Opin Immunol 14 (2002) 615-621
4. Biassoni R., Cantoni C., Pende D., Sivori S., Parolini S., Vitale M., Bottino C., and Moretta A. Human natural killer cell receptors and co-receptors. Immunol Rev 181 (2001) 203-214
5. Raulet D.H., Vance R.E., and McMahon C.W. Regulation of the natural killer cell receptor repertoire. Annu Rev Immunol 19 (2001) 291-330
6. Hansen D.S., Siomos M.A., Buckingham L., Scalzo A.A., and Schofield L. Regulation of murine cerebral malaria pathogenesis by CD1d-restricted NKT cells and the natural killer complex. Immunity 18 (2003) 391-402. This study establishes the control of malaria pathogenesis by NKC loci expressed on CD1d-restricted iNKT cells.
7. Poccia F., Malkovsky M., Gougeon M.L., Bonneville M., Lopez-Botet M., Fournie J.J., and Colizzi V. Gammadelta T cell activation or energy during infections: the role of nonpeptidic TCR ligands and HLA class I molecules. J Leukoc Biol 62 (1997) 287-291
8. Snow R.W., Guerra C.A., Noor A.M., Myint H.Y., and Hay S.I. The global distribution of clinical episodes of Plasmodium falciparum malaria. Nature 434 (2005) 214-217
9. Schofield L., and Grau G. Immunological processes in malaria pathogenesis. Nat Rev Immunol 5 (2005) 722-735
10. Schofield L., and Mueller I. Clinical immunity to malaria. Curr Mol Med 6 (2006) 205-221
11. Kwiatkowski D. Genetic susceptibility to malaria getting complex. Curr Opin Genet Dev 10 (2000) 320-324
12. Stevenson M.M., and Riley E.M. Innate immunity to malaria. Nat Rev Immunol 4 (2004) 169-180
13. Chaicumpa W., Chatkaeomorakot A., Patarapotikul J., and Looareesuwan S. Effects of human natural killer (NK) cells on Plasmodium falciparum infected red cells. Asian Pac J Allergy Immunol 1 (1983) 135-139
14. Orago A., and Facer C.A. Cytotoxicity of human natural killer (NK) cell subsets for Plasmodium falciparum erythrocytic schizonts: stimulation by cytokines and inhibition by neomycin. Clin Exp Immunol 86 (1991) 22-29
15. Theander T.G., Andersen B.J., Pedersen B.K., Jepsen S., and Bygbjerg I.C. Cell-mediated immunity to Plasmodium falciparum infection: evidence against the involvement of cytotoxic lymphocytes. Scand J Immunol 28 (1988) 105-111
16. Saxena Q.B., Biswas S., and Sharma V.P. Interaction of human natural killer cells with plasmodium-infected erythrocytes. Exp Parasitol 69 (1989) 300-302
17. Solomon J.B. Natural cytotoxicity for Plasmodium berghei in vitro by spleen cells from susceptible and resistant rats. Immunology 59 (1986) 277-281
18. Skamene E., Stevenson M.M., and Lemieux S. Murine malaria: dissociation of natural killer (NK) cell activity and resistance to Plasmodium chabaudi. Parasite Immunol 5 (1983) 557-565
19. Solomon J.B., Forbes M.G., and Solomon G.R. A possible role for natural killer cells in providing protection against Plasmodium berghei in early stages of infection. Immunol Lett 9 (1985) 349-352
20. Mohan K., Moulin P., and Stevenson M.M. Natural killer cell cytokine production, not cytotoxicity, contributes to resistance against blood-stage Plasmodium chabaudi AS infection. J Immunol 159 (1997) 4990-4998
21. Hansen D.S., Bernard N.J., Nie C.Q., and Schofield L. NK cells stimulate recruitment of CXCR3+ T cells to the brain during Plasmodium berghei-mediated cerebral malaria. J Immunol 178 (2007) 5779-5788. This study demonstrates that NK cells are essential for fatal cerebral malaria in mice by controlling chemokine-dependent recruitment of CXCR3+ T cells to the brain.
22. Hunt N.H., and Grau G.E. Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria. Trends Immunol 24 (2003) 491-499
23. Yanez D.M., Batchelder J., van der Heyde H.C., Manning D.D., and Weidanz W.P. Gamma delta T-cell function in pathogenesis of cerebral malaria in mice infected with Plasmodium berghei ANKA. Infect Immun 67 (1999) 446-448
24. Nie C.Q., Bernard N.J., Schofield L., and Hansen D.S. CD4+ CD25+ regulatory T cells suppress CD4+ T-cell function and inhibit the development of Plasmodium berghei-specific TH1 responses involved in cerebral malaria pathogenesis. Infect Immun 75 (2007) 2275-2282
25. Grau G.E., Heremans H., Piguet P.F., Pointaire P., Lambert P.H., Billiau A., and Vassalli P. Monoclonal antibody against interferon gamma can prevent experimental cerebral malaria and its associated overproduction of tumor necrosis factor. Proc Natl Acad Sci USA 86 (1989) 5572-5574
26. Engwerda C.R., Mynott T.L., Sawhney S., De Souza J.B., Bickle Q.D., and Kaye P.M. Locally up-regulated lymphotoxin alpha, not systemic tumor necrosis factor alpha, is the principle mediator of murine cerebral malaria. J Exp Med 195 (2002) 1371-1377
27. Sexton A.C., Good R.T., Hansen D.S., D'Ombrain M.C., Buckingham L., Simpson K., and Schofield L. Transcriptional profiling reveals suppressed erythropoiesis, up-regulated glycolysis, and interferon-associated responses in murine malaria. J Infect Dis 189 (2004) 1245-1256
28. Hansen D.S., Evans K.J., D'Ombrain M.C., Bernard N.J., Sexton A.C., Buckingham L., Scalzo A.A., and Schofield L. The natural killer complex regulates severe malarial pathogenesis and influences acquired immune responses to Plasmodium berghei ANKA. Infect Immun 73 (2005) 2288-2297
29. Hansen D.S., Siomos M.A., De Koning-Ward T., Buckingham L., Crabb B.S., and Schofield L. CD1d-restricted NKT cells contribute to malarial splenomegaly and enhance parasite-specific antibody responses. Eur J Immunol 33 (2003) 2588-2598
30. de Kossodo S., and Grau G.E. Profiles of cytokine production in relation with susceptibility to cerebral malaria. J Immunol 151 (1993) 4811-4820
31. Hansen D.S., and Schofield L. Regulation of immunity and pathogenesis in infectious diseases by CD1d-restricted NKT cells. Int J Parasitol 34 (2004) 15-25
32. Yanez D.M., Manning D.D., Cooley A.J., Weidanz W.P., and van der Heyde H.C. Participation of lymphocyte subpopulations in the pathogenesis of experimental murine cerebral malaria. J Immunol 157 (1996) 1620-1624
33. Yokoyama W.M., and Kim S. Licensing of natural killer cells by self-major histocompatibility complex class I. Immunol Rev 214 (2006) 143-154
34. Schofield L., McConville M.J., Hansen D., Campbell A.S., Fraser-Reid B., Grusby M.J., and Tachado S.D. CD1d-restricted immunoglobulin G formation to GPI-anchored antigens mediated by NKT cells. Science 283 (1999) 225-229
35. Hensmann M., and Kwiatkowski D. Cellular basis of early cytokine response to Plasmodium falciparum. Infect Immun 69 (2001) 2364-2371
36. Artavanis-Tsakonas K., and Riley E.M. Innate immune response to malaria: rapid induction of IFNγ from human NK cells by live Plasmodium falciparum-infected erythrocytes. J Immunol 169 (2002) 2956-2963
37. Artavanis-Tsakonas K., Eleme K., McQueen K.L., Cheng N.W., Parham P., Davis D.M., and Riley E.M. Activation of a subset of human NK cells upon contact with Plasmodium falciparum-infected erythrocytes. J Immunol 171 (2003) 5396-5405
38. Korbel D.S., Newman K.C., Almeida C.R., Davis D.M., and Riley E.M. Heterogeneous human NK cell responses to Plasmodium falciparum-infected erythrocytes. J Immunol 175 (2005) 7466-7473. This study identifies NKRs associated with human NK cell activation by malaria parasites.
39. Zevering Y., Amante F., Smillie A., Currier J., Smith G., Houghten R.A., and Good M.F. High frequency of malaria-specific T cells in non-exposed humans. Eur J Immunol 22 (1992) 689-696
40. Ndungu F.M., Sanni L., Urban B., Stephens R., Newbold C.I., Marsh K., and Langhorne J. CD4 T cells from malaria-nonexposed individuals respond to the CD36-Binding Domain of Plasmodium falciparum erythrocyte membrane protein-1 via an MHC class II-TCR-independent pathway. J Immunol 176 (2006) 5504-5512
41. D'Ombrain M.C., Hansen D.S., Simpson K.M., and Schofield L. γδ-T cells expressing NK receptors predominate over NK cells and conventional T cells in the innate IFN-γ response to Plasmodium falciparum malaria. Eur J Immunol 37 (2007) 1864-1873
42. Lanier L.L. NK cell receptors. Annu Rev Immunol 16 (1998) 359-393
43. Braud V.M., Allan D.S., O'Callaghan C.A., Soderstrom K., D'Andrea A., Ogg G.S., Lazetic S., Young N.T., Bell J.I., Phillips J.H., et al. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature 391 (1998) 795-799
44. Ordi J., Menendez C., Ismail M.R., Ventura P.J., Palacin A., Kahigwa E., Ferrer B., Cardesa A., and Alonso P.L. Placental malaria is associated with cell-mediated inflammatory responses with selective absence of natural killer cells. J Infect Dis 183 (2001) 1100-1107
45. Sartelet H., Schleiermacher D., Le-Hesran J.Y., Graesslin O., Gaillard D., Fe M., Lechki C., Gaye A., Le Bouteiller P., and Birembaut P. Less HLA-G expression in Plasmodium falciparum-infected third trimester placentas is associated with more natural killer cells. Placenta 26 (2005) 505-511
46. Jones S.M., Goodier M.R., and Langhorne J. The response of gamma delta T cells to Plasmodium falciparum is dependent on activated CD4+ T cells and the recognition of MHC class I molecules. Immunology 89 (1996) 405-412
47. Newman K.C., Korbel D.S., Hafalla J.C., and Riley E.M. Cross-talk with myeloid accessory cells regulates human natural killer cell interferon-gamma responses to malaria. PLoS Pathog 2 (2006) e118
48. Baratin M., Roetynck S., Lepolard C., Falk C., Sawadogo S., Uematsu S., Akira S., Ryffel B., Tiraby J.G., Alexopoulou L., et al. Natural killer cell and macrophage cooperation in MyD88-dependent innate responses to Plasmodium falciparum. Proc Natl Acad Sci USA 102 (2005) 14747-14752. These two studies identify accessory signals required for the activation of human NK cells by malaria.
49. Togbe D., Schofield L., Grau G.E., Schnyder B., Boissay V., Charron S., Rose S., Beutler B., Quesniaux V.F., and Ryffel B. Murine cerebral malaria development is independent of toll-like receptor signaling. Am J Pathol 170 (2007) 1640-1648
50. Robinson B.A., Welch T.L., and Smith J.D. Widespread functional specialization of Plasmodium falciparum erythrocyte membrane protein 1 family members to bind CD36 analysed across a parasite genome. Mol Microbiol 47 (2003) 1265-1278
51. Urban B., Ferguson D., Pain A., Willcox N., Plebansk iM, Austyn J., and Roberts D. Plasmodium falciparum-infected erythrocytes modulate the maturation of dendritic cells. Nature 400 (1999) 73-77
52. Urban B.C., Willcox N., and Roberts D.J. A role for CD36 in the regulation of dendritic cell function. Proc Natl Acad Sci USA 98 (2001) 8750-8755
53. Elliott S.R., Spurckdodin T.P., Dodin J.M., Maier A.G., Voss T.S., Yosaatmadja F., Payne P.D., McFadden G.I., Cowman A.F., Rogerson S.J., et al. Inhibition of dendritic cell maturation by malaria is dose-dependent and does not require Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1). Infect Immun (2007)
54. D'Ombrain M.C., Voss T.S., Maier A.G., Pearce J.A., Hansen D.S., Cowman A.F., and Schofield L. Plasmodium falciparum erythrocyte membrane protein-1 specifically suppresses early production of host interferon-γ. Cell Host & Microbe (2007) 10.1016/j.chom.2007.06.012
55. Baratin M., Roetynck S., Pouvelle B., Lemmers C., Viebig N.K., Johansson S., Bierling P., Scherf A., Gysin J., Vivier E., et al. Dissection of the role of PfEMP1 and ICAM-1 in the sensing of Plasmodium falciparum-infected erythrocytes by natural killer cells. PLoS ONE 2 (2007) e228
56. Mavoungou E., Held J., Mewono L., and Kremsner P.G. A duffy binding-like domain is involved in the NKp30-mediated recognition of Plasmodium falciparum-parasitized erythrocytes by natural killer cells. J Infect Dis 195 (2007) 1521-1531. These three studies present conflicting data on the regulation of NK cell function by PfEMP-1.
57. Mavoungou E., Luty A.J., and Kremsner P.G. Natural killer (NK) cell-mediated cytolysis of Plasmodium falciparum-infected human red blood cells in vitro. Eur Cytokine Netw 14 (2003) 134-142