-
1
-
-
0030058570
-
Control of the complement system
-
Liszewski MK, Farries TC, Lublin DM, Rooney IA, Atkinson JP. Control of the complement system. Adv Immunol 1996;61:201-83.
-
(1996)
Adv Immunol
, vol.61
, pp. 201-283
-
-
Liszewski, M.K.1
Farries, T.C.2
Lublin, D.M.3
Rooney, I.A.4
Atkinson, J.P.5
-
2
-
-
0025847781
-
Membrane cofactor protein (MCP or CD46): Newest member of the regulators of complement activation gene cluster
-
Liszewski MK, Post TW, Atkinson JP. Membrane cofactor protein (MCP or CD46): newest member of the regulators of complement activation gene cluster. Annu Rev Immunol 1991;9:431-55.
-
(1991)
Annu Rev Immunol
, vol.9
, pp. 431-455
-
-
Liszewski, M.K.1
Post, T.W.2
Atkinson, J.P.3
-
3
-
-
0031018621
-
Complement- regulatory proteins in ovarian malignancies
-
Bjorge L, Hakulinen J, Wahlstrom T, Matre R, Meri S. Complement- regulatory proteins in ovarian malignancies. Int J Cancer 1997;70:14-25.
-
(1997)
Int J Cancer
, vol.70
, pp. 14-25
-
-
Bjorge, L.1
Hakulinen, J.2
Wahlstrom, T.3
Matre, R.4
Meri, S.5
-
4
-
-
0037097650
-
Role of membrane cofactor protein (CD46) in regulation of C4b and C3b deposited on cells
-
Barilla-LaBarca ML, Liszewski MK, Lambris JD, Hourcade D, Atkinson JP. Role of membrane cofactor protein (CD46) in regulation of C4b and C3b deposited on cells. J Immunol 2002;168:6298-304.
-
(2002)
J Immunol
, vol.168
, pp. 6298-6304
-
-
Barilla-LaBarca, M.L.1
Liszewski, M.K.2
Lambris, J.D.3
Hourcade, D.4
Atkinson, J.P.5
-
5
-
-
0029035287
-
Purification and functional properties of soluble forms of membrane cofactor protein (CD46) of complement: Identification of forms increased in cancer patients' sera
-
Seya T, Hara T, Iwata K, et al. Purification and functional properties of soluble forms of membrane cofactor protein (CD46) of complement: identification of forms increased in cancer patients' sera. Int Immunol 1995;7:727-36.
-
(1995)
Int Immunol
, vol.7
, pp. 727-736
-
-
Seya, T.1
Hara, T.2
Iwata, K.3
-
6
-
-
0036554816
-
Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
-
Buettner R, Mora LB, Jove R. Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin Cancer Res 2002;8:945-54.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 945-954
-
-
Buettner, R.1
Mora, L.B.2
Jove, R.3
-
7
-
-
0037112367
-
Constitutive activation of Stat3 in human prostate tumors and cell lines: Direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells
-
Mora LB, Buettner R, Seigne J, et al. Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells. Cancer Res 2002;62:6659-66.
-
(2002)
Cancer Res
, vol.62
, pp. 6659-6666
-
-
Mora, L.B.1
Buettner, R.2
Seigne, J.3
-
8
-
-
0035799531
-
Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells
-
Garcia R, Bowman TL, Niu G, et al. Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells. Oncogene 2001;20:2499-513.
-
(2001)
Oncogene
, vol.20
, pp. 2499-2513
-
-
Garcia, R.1
Bowman, T.L.2
Niu, G.3
-
9
-
-
0035912763
-
Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis
-
Bowman T, Broome MA, Sinibaldi D, et al. Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis. Proc Natl Acad Sci U S A 2002;98:7319-24.
-
(2002)
Proc Natl Acad Sci U S A
, vol.98
, pp. 7319-7324
-
-
Bowman, T.1
Broome, M.A.2
Sinibaldi, D.3
-
10
-
-
0037028249
-
Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells
-
Rahaman SO, Harbor PC, Chernova O, Barnett GH, Vogelbaum MA, Haque SJ. Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells. Oncogene 2002;21:8404-13.
-
(2002)
Oncogene
, vol.21
, pp. 8404-8413
-
-
Rahaman, S.O.1
Harbor, P.C.2
Chernova, O.3
Barnett, G.H.4
Vogelbaum, M.A.5
Haque, S.J.6
-
11
-
-
0032984589
-
Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells
-
Catlett-Falcone R, Landowski TH, Oshiro MM, et al. Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity 1999;10:105-15.
-
(1999)
Immunity
, vol.10
, pp. 105-115
-
-
Catlett-Falcone, R.1
Landowski, T.H.2
Oshiro, M.M.3
-
12
-
-
0034676267
-
Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: Role of activated STAT3 signaling
-
Sinibaldi D, Wharton W, Turkson J, Bowman T, Pledger WJ, Jove R. Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling. Oncogene 2000;19:5419-27.
-
(2000)
Oncogene
, vol.19
, pp. 5419-5427
-
-
Sinibaldi, D.1
Wharton, W.2
Turkson, J.3
Bowman, T.4
Pledger, W.J.5
Jove, R.6
-
13
-
-
0035136846
-
Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression
-
Epling-Burnette PK, Liu JH, Catlett-Falcone R, et al. Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression. J Clin Invest 2001;107:351-62.
-
(2001)
J Clin Invest
, vol.107
, pp. 351-362
-
-
Epling-Burnette, P.K.1
Liu, J.H.2
Catlett-Falcone, R.3
-
14
-
-
0037461934
-
Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis
-
Wei D, Le X, Zheng L, et al. Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis. Oncogene 2003;22:319-29.
-
(2003)
Oncogene
, vol.22
, pp. 319-329
-
-
Wei, D.1
Le, X.2
Zheng, L.3
-
15
-
-
85047695527
-
Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis
-
Niu G, Wright KL, Huang M, et al. Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis. Oncogene 2002;21:2000-8.
-
(2002)
Oncogene
, vol.21
, pp. 2000-2008
-
-
Niu, G.1
Wright, K.L.2
Huang, M.3
-
16
-
-
2442685645
-
Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis
-
Xie TX, Wei D, Liu M, et al. Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis. Oncogene 2004;23:3550-60.
-
(2004)
Oncogene
, vol.23
, pp. 3550-3560
-
-
Xie, T.X.1
Wei, D.2
Liu, M.3
-
17
-
-
11144357779
-
Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells
-
Wang T, Niu G, Kortylewski M, et al. Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells. Nat Med 2004;10:48-54.
-
(2004)
Nat Med
, vol.10
, pp. 48-54
-
-
Wang, T.1
Niu, G.2
Kortylewski, M.3
-
18
-
-
0032560475
-
Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice
-
Kaplan DH, Shankaran V, Dighe AS, et al. Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice. Proc Natl Acad Sci U S A 1998;95:7556-61.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 7556-7561
-
-
Kaplan, D.H.1
Shankaran, V.2
Dighe, A.S.3
-
19
-
-
4744364574
-
Alternative activation of STAT1 and STAT3 in response to interferon-γ
-
Qing Y, Stark GR. Alternative activation of STAT1 and STAT3 in response to interferon-γ. J Biol Chem 2004;279:41679-85.
-
(2004)
J Biol Chem
, vol.279
, pp. 41679-41685
-
-
Qing, Y.1
Stark, G.R.2
-
20
-
-
1042302005
-
The STATs of cancer - new molecular targets come of age
-
Yu H, Jove R. The STATs of cancer - new molecular targets come of age. Nat Rev Cancer 2004;4:97-105.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 97-105
-
-
Yu, H.1
Jove, R.2
-
21
-
-
0028937707
-
Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity
-
Seidel HM, Milocco LH, Lamb P, Darnell JE, Jr., Stein RB, Rosen J. Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity. Proc Natl Acad Sci U S A 1995;92:3041-5.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 3041-3045
-
-
Seidel, H.M.1
Milocco, L.H.2
Lamb, P.3
Darnell Jr., J.E.4
Stein, R.B.5
Rosen, J.6
-
22
-
-
0029069540
-
Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein
-
Yu CL, Meyer DJ, Campbell GS, et al. Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. Science 1995;269:81-3.
-
(1995)
Science
, vol.269
, pp. 81-83
-
-
Yu, C.L.1
Meyer, D.J.2
Campbell, G.S.3
-
23
-
-
0031953831
-
Stat3 activation by Src induces specific gene regulation and is required for cell transformation
-
Turkson J, Bowman T, Garcia R, Caldenhoven E, De Groot RP, Jove R. Stat3 activation by Src induces specific gene regulation and is required for cell transformation. Mol Cell Biol 1998;18:2545-52.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 2545-2552
-
-
Turkson, J.1
Bowman, T.2
Garcia, R.3
Caldenhoven, E.4
De Groot, R.P.5
Jove, R.6
-
24
-
-
0029970628
-
Engineering of recombinant soluble CD46: An inhibitor of complement activation
-
Christiansen D, Milland J, Thorley BR, et al. Engineering of recombinant soluble CD46: an inhibitor of complement activation. Immunology 1996;87:348-54.
-
(1996)
Immunology
, vol.87
, pp. 348-354
-
-
Christiansen, D.1
Milland, J.2
Thorley, B.R.3
-
25
-
-
0027184998
-
Membrane cofactor protein (CD46) protects cells predominantly from alternative complement pathway-mediated C3-fragment deposition and cytolysis
-
Kojima A, Iwata K, Seya T, et al. Membrane cofactor protein (CD46) protects cells predominantly from alternative complement pathway-mediated C3-fragment deposition and cytolysis. J Immunol 1993;151:1519-27.
-
(1993)
J Immunol
, vol.151
, pp. 1519-1527
-
-
Kojima, A.1
Iwata, K.2
Seya, T.3
-
26
-
-
0034292339
-
Cooperation between decay-accelerating factor and membrane cofactor protein in protecting cells from autologous complement attack
-
Brodbeck WG, Mold C, Atkinson JP, Medof ME. Cooperation between decay-accelerating factor and membrane cofactor protein in protecting cells from autologous complement attack. J Immunol 2000;165:3999-4006.
-
(2000)
J Immunol
, vol.165
, pp. 3999-4006
-
-
Brodbeck, W.G.1
Mold, C.2
Atkinson, J.P.3
Medof, M.E.4
-
27
-
-
0029923882
-
Characterisation of the complement-regulatory proteins decay-accelerating factor (DAF, CD55) and membrane cofactor protein (MCP, CD46) on a human colonic adenocarcinoma cell line
-
Bjorge L, Jensen TS, Matre R. Characterisation of the complement-regulatory proteins decay-accelerating factor (DAF, CD55) and membrane cofactor protein (MCP, CD46) on a human colonic adenocarcinoma cell line. Cancer Immunol Immunother 1996;42:185-92.
-
(1996)
Cancer Immunol Immunother
, vol.42
, pp. 185-192
-
-
Bjorge, L.1
Jensen, T.S.2
Matre, R.3
-
28
-
-
0027432063
-
Characterization of the promoter region of the membrane cofactor protein (CD46) gene of the human complement system and comparison to a membrane cofactor protein-like genetic element
-
Cui W, Hourcade D, Post T, Greenlund AC, Atkinson JP, Kumar V. Characterization of the promoter region of the membrane cofactor protein (CD46) gene of the human complement system and comparison to a membrane cofactor protein-like genetic element. J Immunol 1993;151:4137-46.
-
(1993)
J Immunol
, vol.151
, pp. 4137-4146
-
-
Cui, W.1
Hourcade, D.2
Post, T.3
Greenlund, A.C.4
Atkinson, J.P.5
Kumar, V.6
-
29
-
-
0028176302
-
Chimeric anti-ganglioside GM2 antibody with antitumor activity
-
Nakamura K, Koike M, Shitara K, et al. Chimeric anti-ganglioside GM2 antibody with antitumor activity. Cancer Res 1994;54:1511-6.
-
(1994)
Cancer Res
, vol.54
, pp. 1511-1516
-
-
Nakamura, K.1
Koike, M.2
Shitara, K.3
-
30
-
-
0031048165
-
Tumour necrosis factor-a up-regulates decay-accelerating factor gene expression in human intestinal epithelial cells
-
Andoh A, Fujiyama Y, Sumiyoshi K, Sakumoto H, Okabe H, Bamba T. Tumour necrosis factor-a up-regulates decay-accelerating factor gene expression in human intestinal epithelial cells. Immunology 1997;90:358-63.
-
(1997)
Immunology
, vol.90
, pp. 358-363
-
-
Andoh, A.1
Fujiyama, Y.2
Sumiyoshi, K.3
Sakumoto, H.4
Okabe, H.5
Bamba, T.6
-
31
-
-
0030724920
-
Lack of effect of different cytokines on expression of membrane-bound regulators of complement activity on human uveal melanoma cells
-
Blom DJ, Goslings WR, DeWaard-Siebinga I, et al. Lack of effect of different cytokines on expression of membrane-bound regulators of complement activity on human uveal melanoma cells. J Interferon Cytokine Res 1997;17:695-700.
-
(1997)
J Interferon Cytokine Res
, vol.17
, pp. 695-700
-
-
Blom, D.J.1
Goslings, W.R.2
DeWaard-Siebinga, I.3
-
32
-
-
0032718891
-
Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo
-
Niu G, Heller R, Catlett-Falcone R, et al. Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo. Cancer Res 1999;59:5059-63.
-
(1999)
Cancer Res
, vol.59
, pp. 5059-5063
-
-
Niu, G.1
Heller, R.2
Catlett-Falcone, R.3
-
33
-
-
0035977055
-
Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation
-
Turkson J, Ryan D, Kim JS, et al. Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation. J Biol Chem 2001;276:45443-55.
-
(2001)
J Biol Chem
, vol.276
, pp. 45443-45455
-
-
Turkson, J.1
Ryan, D.2
Kim, J.S.3
-
34
-
-
3543055012
-
Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity
-
Turkson J, Kim JS, Zhang S, et al. Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity. Mol Cancer Ther 2004;3:261-9.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 261-269
-
-
Turkson, J.1
Kim, J.S.2
Zhang, S.3
-
35
-
-
12344328541
-
Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity
-
Turkson J, Zhang S, Palmer J, et al. Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity. Mol Cancer Ther 2004;3:1533-42.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 1533-1542
-
-
Turkson, J.1
Zhang, S.2
Palmer, J.3
-
36
-
-
0034659107
-
STAT3 regulates the growth and immunoglobulin production of BCL(1) B cell lymphoma through control of cell cycle progression
-
Karras JG, McKay RA, Lu T, et al. STAT3 regulates the growth and immunoglobulin production of BCL(1) B cell lymphoma through control of cell cycle progression. Cell Immunol 2000;202:124-35.
-
(2000)
Cell Immunol
, vol.202
, pp. 124-135
-
-
Karras, J.G.1
McKay, R.A.2
Lu, T.3
-
37
-
-
0025639009
-
The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter
-
Wagner BJ, Hayes TE, Hoban CJ, Cochran BH. The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter. EMBO J 1990;9:4477-84.
-
(1990)
EMBO J
, vol.9
, pp. 4477-4484
-
-
Wagner, B.J.1
Hayes, T.E.2
Hoban, C.J.3
Cochran, B.H.4
|