-
1
-
-
34548071005
-
Secreted frizzled-related protein 1 loss contributes to tumor phenotype of clear cell renal cell carcinoma
-
Gumz ML, Zou H, Kreinest PA, et al. Secreted frizzled-related protein 1 loss contributes to tumor phenotype of clear cell renal cell carcinoma. Clin Cancer Res 2007;13:4740-9.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4740-4749
-
-
Gumz, M.L.1
Zou, H.2
Kreinest, P.A.3
-
2
-
-
33746808398
-
Wnt/β-catenin signaling in development and disease
-
Clevers H. Wnt/β-catenin signaling in development and disease. Cell 2006;127:469-80.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
4
-
-
12644269195
-
Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action
-
Finch PW, He X, Kelley MJ, et al. Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action. Proc Natl Acad Sci U S A 1997;94:6770-5.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 6770-6775
-
-
Finch, P.W.1
He, X.2
Kelley, M.J.3
-
5
-
-
0030933978
-
Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer
-
Leyns L, Bouwmeester T, Kim SH, Piccolo S, De Robertis EM. Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer. Cell 1997;88:747-56.
-
(1997)
Cell
, vol.88
, pp. 747-756
-
-
Leyns, L.1
Bouwmeester, T.2
Kim, S.H.3
Piccolo, S.4
De Robertis, E.M.5
-
6
-
-
33845778949
-
Wnt antagonist family genes as biomarkers for diagnosis, staging, and prognosis of renal cell carcinoma using tumor and serum DNA
-
Urakami S, Shiina H, Enokida H, et al. Wnt antagonist family genes as biomarkers for diagnosis, staging, and prognosis of renal cell carcinoma using tumor and serum DNA. Clin Cancer Res 2006;12:6989-97.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6989-6997
-
-
Urakami, S.1
Shiina, H.2
Enokida, H.3
-
7
-
-
34547943693
-
Frequent loss of SFRP1 expression in multiple human solid tumours: Associationwith aberrant promoter methylation in renal cell carcinoma
-
Dahl E, Wiesmann F, Woenckhaus M, et al. Frequent loss of SFRP1 expression in multiple human solid tumours: associationwith aberrant promoter methylation in renal cell carcinoma. Oncogene 2007.
-
(2007)
Oncogene
-
-
Dahl, E.1
Wiesmann, F.2
Woenckhaus, M.3
-
8
-
-
33846876103
-
Identification of the genes for kidney cancer: Opportunity for disease-specific targeted therapeutics
-
s
-
Linehan WM, Pinto PA, Srinivasan R, et al. Identification of the genes for kidney cancer: opportunity for disease-specific targeted therapeutics. Clin Cancer Res 2007;13:671-9s.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 671-679
-
-
Linehan, W.M.1
Pinto, P.A.2
Srinivasan, R.3
-
9
-
-
33751161268
-
The cellular basis of kidney development
-
Dressler GR. The cellular basis of kidney development. Annu Rev Cell Dev Biol 2006;22:509-29.
-
(2006)
Annu Rev Cell Dev Biol
, vol.22
, pp. 509-529
-
-
Dressler, G.R.1
-
10
-
-
7944230668
-
An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells
-
Bafico A, Liu G, Goldin L, Harris V, Aaronson SA. An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells. Cancer Cell 2004;6:497-506.
-
(2004)
Cancer Cell
, vol.6
, pp. 497-506
-
-
Bafico, A.1
Liu, G.2
Goldin, L.3
Harris, V.4
Aaronson, S.A.5
-
11
-
-
12144291274
-
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer
-
Suzuki H, Watkins DN, Jair KW, et al. Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nat Genet 2004;36:417-22.
-
(2004)
Nat Genet
, vol.36
, pp. 417-422
-
-
Suzuki, H.1
Watkins, D.N.2
Jair, K.W.3
-
12
-
-
0036528247
-
Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma
-
Weeraratna AT, Jiang Y, Hostetter G, et al. Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma. Cancer Cell 2002;1:279-88.
-
(2002)
Cancer Cell
, vol.1
, pp. 279-288
-
-
Weeraratna, A.T.1
Jiang, Y.2
Hostetter, G.3
-
13
-
-
33846396811
-
Frizzled/PCP signalling: A conserved mechanism regulating cell polarity and directed motility
-
Seifert JR, Mlodzik M. Frizzled/PCP signalling: a conserved mechanism regulating cell polarity and directed motility. Nat Rev Genet 2007;8:126-38.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 126-138
-
-
Seifert, J.R.1
Mlodzik, M.2
-
14
-
-
0036613250
-
A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer
-
Suzuki H, Gabrielson E, Chen W, et al. A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer. Nat Genet 2002;31:141-9.
-
(2002)
Nat Genet
, vol.31
, pp. 141-149
-
-
Suzuki, H.1
Gabrielson, E.2
Chen, W.3
-
15
-
-
13644251086
-
Loss of SFRP1 is associated with breast cancer progression and poor prognosis in early stage tumors
-
Klopocki E, Kristiansen G, Wild PJ, et al. Loss of SFRP1 is associated with breast cancer progression and poor prognosis in early stage tumors. Int J Oncol 2004;25:641-9.
-
(2004)
Int J Oncol
, vol.25
, pp. 641-649
-
-
Klopocki, E.1
Kristiansen, G.2
Wild, P.J.3
-
16
-
-
12144288255
-
Decreased expression of REIC/Dkk-3 in human renal clear cell carcinoma
-
Kurose K, Sakaguchi M, Nasu Y, et al. Decreased expression of REIC/Dkk-3 in human renal clear cell carcinoma. J Urol 2004;171:1314-8.
-
(2004)
J Urol
, vol.171
, pp. 1314-1318
-
-
Kurose, K.1
Sakaguchi, M.2
Nasu, Y.3
-
17
-
-
27544457678
-
Adenovirus-mediated overexpression of REIC/Dkk-3 selectively induces apoptosis in human prostate cancer cells through activation of c-Jun-NH2-kinase
-
Abarzua F, Sakaguchi M, Takaishi M, et al. Adenovirus-mediated overexpression of REIC/Dkk-3 selectively induces apoptosis in human prostate cancer cells through activation of c-Jun-NH2-kinase. Cancer Res 2005;65:9617-22.
-
(2005)
Cancer Res
, vol.65
, pp. 9617-9622
-
-
Abarzua, F.1
Sakaguchi, M.2
Takaishi, M.3
-
18
-
-
33846643931
-
The role of VHL in the regulation of E-cadherin: A new connection in an old pathway
-
Russell RC, Ohh M. The role of VHL in the regulation of E-cadherin: a new connection in an old pathway. Cell Cycle 2007;6:56-9.
-
(2007)
Cell Cycle
, vol.6
, pp. 56-59
-
-
Russell, R.C.1
Ohh, M.2
-
19
-
-
33645302628
-
The epithelial-mesenchymal transition: New insights in signaling, development and disease
-
Lee JM, Dedkar S, Kalluri R, Thompson EW. The epithelial-mesenchymal transition: new insights in signaling, development and disease. J Cell Biol 2006;172:973-81.
-
(2006)
J Cell Biol
, vol.172
, pp. 973-981
-
-
Lee, J.M.1
Dedkar, S.2
Kalluri, R.3
Thompson, E.W.4
-
20
-
-
0034908762
-
Oncogenic mutants of RON and MET receptor tyrosine kinases cause activation of the β-catenin pathway
-
Danilkovitch-Miagkova A, Miagkov A, Skeel A, Nakaigawa N, Zbar B, Leonard EJ. Oncogenic mutants of RON and MET receptor tyrosine kinases cause activation of the β-catenin pathway. Mol Cell Biol 2001;21:5857-68.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5857-5868
-
-
Danilkovitch-Miagkova, A.1
Miagkov, A.2
Skeel, A.3
Nakaigawa, N.4
Zbar, B.5
Leonard, E.J.6
-
21
-
-
4444276194
-
Essential role of BCL9-2 in the switch between β-catenin's adhesive and transcriptional functions
-
Brembeck FH, Schwarz-Romond T, Bakkers J, Wilhelm S, Hammerschmidt M, Birchmeier W. Essential role of BCL9-2 in the switch between β-catenin's adhesive and transcriptional functions. Genes Dev 2004;18:2225-30.
-
(2004)
Genes Dev
, vol.18
, pp. 2225-2230
-
-
Brembeck, F.H.1
Schwarz-Romond, T.2
Bakkers, J.3
Wilhelm, S.4
Hammerschmidt, M.5
Birchmeier, W.6
-
22
-
-
0036718539
-
Molecular basis of the VHL hereditary cancer syndrome
-
Kaelin WG, Jr. Molecular basis of the VHL hereditary cancer syndrome. Nat Rev Cancer 2002;2:673-82.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 673-682
-
-
Kaelin Jr., W.G.1
-
23
-
-
33749238874
-
The von Hippel-Lindau tumor suppressor gene product represses oncogenic h-catenin signaling in renal carcinoma cells
-
Peruzzi B, Athauda G, Bottaro DP. The von Hippel-Lindau tumor suppressor gene product represses oncogenic h-catenin signaling in renal carcinoma cells. Proc Natl Acad Sci U S A 2006;103:14531-6.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 14531-14536
-
-
Peruzzi, B.1
Athauda, G.2
Bottaro, D.P.3
-
24
-
-
33947217823
-
Interaction between β-catenin and HIF-1 promotes cellular adaptation to hypoxia
-
Kaidi A, Williams AC, Paraskeva C. Interaction between β-catenin and HIF-1 promotes cellular adaptation to hypoxia. Nat Cell Biol 2007;9:210-7.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 210-217
-
-
Kaidi, A.1
Williams, A.C.2
Paraskeva, C.3
-
25
-
-
33846821872
-
Targeted therapy for metastatic renal cell carcinoma
-
Motzer RJ, Bukowski RM. Targeted therapy for metastatic renal cell carcinoma. J Clin Oncol 2006;24:5601-8.
-
(2006)
J Clin Oncol
, vol.24
, pp. 5601-5608
-
-
Motzer, R.J.1
Bukowski, R.M.2
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