-
1
-
-
18144416611
-
The transcriptional targets of p53 in apoptosis control
-
Yu J, Zhang L. The transcriptional targets of p53 in apoptosis control. Biochem Biophys Res Commun 2005; 331: 851-858.
-
(2005)
Biochem Biophys Res Commun
, vol.331
, pp. 851-858
-
-
Yu, J.1
Zhang, L.2
-
2
-
-
0029803281
-
Wild-type p53 negatively regulates the expression of a microtubule-associated protein
-
Murphy M, Hinman A, Levine AJ. Wild-type p53 negatively regulates the expression of a microtubule-associated protein. Genes Dev 1996; 10: 2971-2980.
-
(1996)
Genes Dev
, vol.10
, pp. 2971-2980
-
-
Murphy, M.1
Hinman, A.2
Levine, A.J.3
-
3
-
-
0030983240
-
Inhibition of protein phosphatase activity induces p53-dependent apoptosis in the absence of p53 transactivation
-
Yan Y, Shay JW, Wright WE, Mumby MC. Inhibition of protein phosphatase activity induces p53-dependent apoptosis in the absence of p53 transactivation. J Biol Chem 1997; 272: 15220-15226.
-
(1997)
J Biol Chem
, vol.272
, pp. 15220-15226
-
-
Yan, Y.1
Shay, J.W.2
Wright, W.E.3
Mumby, M.C.4
-
4
-
-
0035137882
-
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB
-
Baldwin AS. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. J Clin Invest 2001; 107: 241-246.
-
(2001)
J Clin Invest
, vol.107
, pp. 241-246
-
-
Baldwin, A.S.1
-
5
-
-
0036845841
-
Activation of nuclear factor-kappaB during doxorubicin-induced apoptosis in endothelial cells and myocytes is pro-apoptotic: The role of hydrogen peroxide
-
Wang S, Kotamraju S, Konorev E, Kalivendi S, Joseph J, Kalyanaraman B. Activation of nuclear factor-kappaB during doxorubicin-induced apoptosis in endothelial cells and myocytes is pro-apoptotic: The role of hydrogen peroxide. Biochem J 2002; 367: 729-740.
-
(2002)
Biochem J
, vol.367
, pp. 729-740
-
-
Wang, S.1
Kotamraju, S.2
Konorev, E.3
Kalivendi, S.4
Joseph, J.5
Kalyanaraman, B.6
-
6
-
-
1842526076
-
Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B
-
Campbell KJ, Rocha S, Perkins ND. Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B. Mol Cell 2004; 13: 853-865.
-
(2004)
Mol Cell
, vol.13
, pp. 853-865
-
-
Campbell, K.J.1
Rocha, S.2
Perkins, N.D.3
-
7
-
-
0037421484
-
NF-kappaB blockade and oncogenic Ras trigger invasive human apidermal neoplasia
-
Dajee M, Lazarov M, Zhang JY, Cai T, Green CL, Russell AJ et al. NF-kappaB blockade and oncogenic Ras trigger invasive human apidermal neoplasia. Nature 2003; 421: 639-643.
-
(2003)
Nature
, vol.421
, pp. 639-643
-
-
Dajee, M.1
Lazarov, M.2
Zhang, J.Y.3
Cai, T.4
Green, C.L.5
Russell, A.J.6
-
8
-
-
0029166389
-
Proenkephalin is a nuclear protein responsive to growth arrest and differentiation signals
-
Bottger A, Spruce BA. Proenkephalin is a nuclear protein responsive to growth arrest and differentiation signals. J Cell Biol 1995; 130: 1251-1262.
-
(1995)
J Cell Biol
, vol.130
, pp. 1251-1262
-
-
Bottger, A.1
Spruce, B.A.2
-
9
-
-
4143066901
-
Opioids as modulators of cell death and survival - unraveling mechanisms and revealing new indications
-
Tegeder I, Geisslinger G. Opioids as modulators of cell death and survival - unraveling mechanisms and revealing new indications. Pharmacol Rev 2004; 56: 351-369.
-
(2004)
Pharmacol Rev
, vol.56
, pp. 351-369
-
-
Tegeder, I.1
Geisslinger, G.2
-
10
-
-
0037446984
-
G protein-independent G1 cell cycle block and apoptosis with morphine in adenocarcinoma cells: Involvement of p53 phosphorylation
-
Tegeder I, Grosch S, Schmidtko A, Haussler A, Schmidt H, Niederberger E et al. G protein-independent G1 cell cycle block and apoptosis with morphine in adenocarcinoma cells: Involvement of p53 phosphorylation. Cancer Res 2003; 63: 1846-1852.
-
(2003)
Cancer Res
, vol.63
, pp. 1846-1852
-
-
Tegeder, I.1
Grosch, S.2
Schmidtko, A.3
Haussler, A.4
Schmidt, H.5
Niederberger, E.6
-
12
-
-
33751549096
-
SUMO-specific protease SUSP4 positively regulates p53 by promoting Mdm2 self-ubiquitination
-
Lee MH, Lee SW, Lee EJ, Choi SJ, Chung SS, Lee JI et al. SUMO-specific protease SUSP4 positively regulates p53 by promoting Mdm2 self-ubiquitination. Nat Cell Biol 2006; 8: 1424-1431.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1424-1431
-
-
Lee, M.H.1
Lee, S.W.2
Lee, E.J.3
Choi, S.J.4
Chung, S.S.5
Lee, J.I.6
-
13
-
-
0031826298
-
Elevated proenkephalin-derived peptide levels in ACTH-producing adenomas: Nucleus and cytoplasm localization
-
Vindrola O, Chervin A, Vitale M, Mella AN, Aloyz R, Basso A. Elevated proenkephalin-derived peptide levels in ACTH-producing adenomas: Nucleus and cytoplasm localization. Endocrine 1998; 8: 231-240.
-
(1998)
Endocrine
, vol.8
, pp. 231-240
-
-
Vindrola, O.1
Chervin, A.2
Vitale, M.3
Mella, A.N.4
Aloyz, R.5
Basso, A.6
-
14
-
-
0034916694
-
The trigger to cell death determines the efficiency with which dying cells are cleared by neighbours
-
Wiegand UK, Corbach S, Prescott AR, Savill J, Spruce BA. The trigger to cell death determines the efficiency with which dying cells are cleared by neighbours. Cell Death Differ 2001; 8: 734-746.
-
(2001)
Cell Death Differ
, vol.8
, pp. 734-746
-
-
Wiegand, U.K.1
Corbach, S.2
Prescott, A.R.3
Savill, J.4
Spruce, B.A.5
-
15
-
-
0032954928
-
Transcriptional cross talk between NF-kappaB and p53
-
Webster GA, Perkins ND. Transcriptional cross talk between NF-kappaB and p53. Mol Cell Biol 1999; 19: 3485-3495.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 3485-3495
-
-
Webster, G.A.1
Perkins, N.D.2
-
16
-
-
0033947601
-
The pro- or anti-apoptotic function of NF-kappaB is determined by the nature of the apoptotic stimulus
-
Kaltschmidt B, Kaltschmidt C, Hofmann TG, Hehner SP, Droge W, Schmitz ML. The pro- or anti-apoptotic function of NF-kappaB is determined by the nature of the apoptotic stimulus. Eur J Biochem, 2000; 267 3828-3835.
-
(2000)
Eur J Biochem
, vol.267
, pp. 3828-3835
-
-
Kaltschmidt, B.1
Kaltschmidt, C.2
Hofmann, T.G.3
Hehner, S.P.4
Droge, W.5
Schmitz, M.L.6
-
17
-
-
0029976817
-
An essential role for NF-kappaB in preventing TNF-alpha-induced cell death
-
Beg AA, Baltimore D. An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science 1996; 274: 782-784.
-
(1996)
Science
, vol.274
, pp. 782-784
-
-
Beg, A.A.1
Baltimore, D.2
-
18
-
-
0026546865
-
Distinct combinations of NF-kappa B subunits determine the specificity of transcriptional activation
-
Perkins ND, Schmid RM, Duckett CS, Leung K, Rice NR, Nabel GJ. Distinct combinations of NF-kappa B subunits determine the specificity of transcriptional activation. Proc Natl Acad Sci USA 1992; 89: 1529-1533.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 1529-1533
-
-
Perkins, N.D.1
Schmid, R.M.2
Duckett, C.S.3
Leung, K.4
Rice, N.R.5
Nabel, G.J.6
-
19
-
-
0027983512
-
An interaction between the DNA-binding domains of RelA(p65) and Sp1 mediates human immunodeficiency virus gene activation
-
Perkins ND, Agranoff AB, Pascal E, Nabel GJ. An interaction between the DNA-binding domains of RelA(p65) and Sp1 mediates human immunodeficiency virus gene activation. Mol Cell Biol 1994; 14: 6570-6583.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 6570-6583
-
-
Perkins, N.D.1
Agranoff, A.B.2
Pascal, E.3
Nabel, G.J.4
-
20
-
-
0034689773
-
Role of NF-kappaB in p53-mediated programmed cell death
-
Ryan KM, Ernst MK, Rice NR, Vousden KH. Role of NF-kappaB in p53-mediated programmed cell death. Nature 2000; 404: 892-897.
-
(2000)
Nature
, vol.404
, pp. 892-897
-
-
Ryan, K.M.1
Ernst, M.K.2
Rice, N.R.3
Vousden, K.H.4
-
21
-
-
0025854757
-
Sequence similarity between opioid peptide precursors and DNA-binding proteins
-
Bakalkin G, Ponomarlev D, Sarkisyan RA, Terenius L. Sequence similarity between opioid peptide precursors and DNA-binding proteins. FEBS Lett 1991; 282: 175-177.
-
(1991)
FEBS Lett
, vol.282
, pp. 175-177
-
-
Bakalkin, G.1
Ponomarlev, D.2
Sarkisyan, R.A.3
Terenius, L.4
-
22
-
-
0036337748
-
A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells
-
He KL, Ting AT. A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells. Mol Cell Biol 2002; 22: 6034-6045.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 6034-6045
-
-
KL, H.1
Ting, A.T.2
-
23
-
-
18644372124
-
-
Li J, Tan M, Li L, Pamarthy D, Lawrence TS, Sun Y. SAK, a new polo-like kinase, is transcriptionally repressed by p53 and induces apoptosis upon RNAi silencing. Neoplasia 2005; 7: 312-323.
-
Li J, Tan M, Li L, Pamarthy D, Lawrence TS, Sun Y. SAK, a new polo-like kinase, is transcriptionally repressed by p53 and induces apoptosis upon RNAi silencing. Neoplasia 2005; 7: 312-323.
-
-
-
-
24
-
-
0036479115
-
Transcriptional repression of the anti-apoptotic survivin gene by wild type p53
-
Hoffman WH, Biade S, Ziffou JT, Chen J, Murphy M. Transcriptional repression of the anti-apoptotic survivin gene by wild type p53. J Biol Chem 2002; 277: 3247-3257.
-
(2002)
J Biol Chem
, vol.277
, pp. 3247-3257
-
-
Hoffman, W.H.1
Biade, S.2
Ziffou, J.T.3
Chen, J.4
Murphy, M.5
-
25
-
-
0031048422
-
Repression of glucocorticoid receptor transactivation and DNA binding of a glucocorticoid response element within the serum/glucocorticoid-inducible protein kinase (sgk) gene promoter by the p53 tumor suppressor protein
-
Maiyar AC, Phu PT, Huang AJ, Firestone GL. Repression of glucocorticoid receptor transactivation and DNA binding of a glucocorticoid response element within the serum/glucocorticoid-inducible protein kinase (sgk) gene promoter by the p53 tumor suppressor protein. Mol Endocrinol 1997; 11: 312-329.
-
(1997)
Mol Endocrinol
, vol.11
, pp. 312-329
-
-
Maiyar, A.C.1
Phu, P.T.2
Huang, A.J.3
Firestone, G.L.4
-
26
-
-
0027168447
-
NF-kappa B controls expression of inhibitor I kappa B alpha: Evidence for an inducible autoregulatory pathway
-
Sun SC, Ganchi PA, Ballard DW, Greene WC. NF-kappa B controls expression of inhibitor I kappa B alpha: Evidence for an inducible autoregulatory pathway. Science 1993; 259: 1912-1915.
-
(1993)
Science
, vol.259
, pp. 1912-1915
-
-
Sun, S.C.1
Ganchi, P.A.2
Ballard, D.W.3
Greene, W.C.4
-
27
-
-
0034802887
-
The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression
-
Ashbumer BP, Westerheide SD, Baldwin Jr AS. The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. Mol Cell Biol 2001; 21: 7065-7077.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 7065-7077
-
-
Ashbumer, B.P.1
Westerheide, S.D.2
Baldwin Jr, A.S.3
-
28
-
-
0033215387
-
Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a
-
Murphy M, Ahn J, Walker KK, Hoffman WH, Evans RM, Levine AJ et al. Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a. Genes Dev 1999; 13: 2490-2501.
-
(1999)
Genes Dev
, vol.13
, pp. 2490-2501
-
-
Murphy, M.1
Ahn, J.2
Walker, K.K.3
Hoffman, W.H.4
Evans, R.M.5
Levine, A.J.6
-
29
-
-
1642553460
-
To be, or not to be: NF-kappaB is the answer - role of Rel/NF-kappaB in this regulation of apoptosis
-
Kucharczak J, Simmons MJ, Fan Y, Gelinas C. To be, or not to be: NF-kappaB is the answer - role of Rel/NF-kappaB in this regulation of apoptosis. Oncogene 2003; 22: 8961-8982.
-
(2003)
Oncogene
, vol.22
, pp. 8961-8982
-
-
Kucharczak, J.1
Simmons, M.J.2
Fan, Y.3
Gelinas, C.4
-
30
-
-
0029858387
-
TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB
-
Wang CY, Mayo MW, Baldwin Jr AS. TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB. Science 1996; 274: 784-787.
-
(1996)
Science
, vol.274
, pp. 784-787
-
-
Wang, C.Y.1
Mayo, M.W.2
Baldwin Jr, A.S.3
-
31
-
-
0035140981
-
Regulation of p53 by hypoxia: Dissociation of transcriptional repression and apoptosis from p53-dependent transactivation
-
Koumenis C, Alarcon R, Hammond E, Sutphin P, Hoffman W, Murphy M et al. Regulation of p53 by hypoxia: Dissociation of transcriptional repression and apoptosis from p53-dependent transactivation. Mol Cell Biol 2001; 21: 1297-1310.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1297-1310
-
-
Koumenis, C.1
Alarcon, R.2
Hammond, E.3
Sutphin, P.4
Hoffman, W.5
Murphy, M.6
-
33
-
-
3142771914
-
Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response
-
Saccani S, Marazzi I, Beg AA, Natoli G. Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response. J Exp Med 2004; 200: 107-113.
-
(2004)
J Exp Med
, vol.200
, pp. 107-113
-
-
Saccani, S.1
Marazzi, I.2
Beg, A.A.3
Natoli, G.4
-
34
-
-
21744432851
-
Differences in the association of p53 phosphorylated on serine 15 and key enzymes of homologous recombination
-
Restle A, Janz C, Wiesmuller L. Differences in the association of p53 phosphorylated on serine 15 and key enzymes of homologous recombination. Oncogene 2005; 24: 4380-4387.
-
(2005)
Oncogene
, vol.24
, pp. 4380-4387
-
-
Restle, A.1
Janz, C.2
Wiesmuller, L.3
-
35
-
-
0037223362
-
Regulation of RelA (p65) function by the large subunit of replication G
-
Anderson LA, Perkins ND. Regulation of RelA (p65) function by the large subunit of replication G. Mol Cell Biol 2003; 23: 721-732.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 721-732
-
-
Anderson, L.A.1
Perkins, N.D.2
-
36
-
-
4744350876
-
Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo
-
Saville MK, Sparks A, Xirodimas DP, Wardrop J, Stevenson LF, Bourdon JC et al. Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo. J Biol Chem 2004, 279: 42169-42181.
-
(2004)
J Biol Chem
, vol.279
, pp. 42169-42181
-
-
Saville, M.K.1
Sparks, A.2
Xirodimas, D.P.3
Wardrop, J.4
Stevenson, L.F.5
Bourdon, J.C.6
-
37
-
-
0037119388
-
The large subunit of replication factor C interacts with the histone deacetylase HDAC1
-
Anderson LA, Perkins ND. The large subunit of replication factor C interacts with the histone deacetylase HDAC1. J Biol Chem 2002; 277: 29550-29554.
-
(2002)
J Biol Chem
, vol.277
, pp. 29550-29554
-
-
Anderson, L.A.1
Perkins, N.D.2
-
38
-
-
0038409927
-
p53 represses cyclin D1 transcription through down regulation of Bcl-3 and inducing increased association of the p52 NF-kappaB subunit with histone deacetylase 1
-
Rocha S, Martin AM, Meek DW, Perkins ND. p53 represses cyclin D1 transcription through down regulation of Bcl-3 and inducing increased association of the p52 NF-kappaB subunit with histone deacetylase 1: Mol Cell Biol 2003; 23: 4713-4727.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 4713-4727
-
-
Rocha, S.1
Martin, A.M.2
Meek, D.W.3
Perkins, N.D.4
-
39
-
-
0029928512
-
Modification of an N-terminal regulatory domain of T antigen restores p53-T antigen complex formation in the absence of an essential metal ion cofactor
-
Kemohan NM, Hupp TR, Lane DP. Modification of an N-terminal regulatory domain of T antigen restores p53-T antigen complex formation in the absence of an essential metal ion cofactor. J Biol Chem 1996; 271: 4954-4960.
-
(1996)
J Biol Chem
, vol.271
, pp. 4954-4960
-
-
Kemohan, N.M.1
Hupp, T.R.2
Lane, D.P.3
-
40
-
-
3142699893
-
Small molecule antagonists of the sigma-1 receptor cause selective release of the death program in tumor and self-reliant calls and inhibit tumor growth in vitro and in vivo
-
Spruce BA, Campbell LA, McTavish N, Cooper MA, Appleyard MV, O'Neill M et al. Small molecule antagonists of the sigma-1 receptor cause selective release of the death program in tumor and self-reliant calls and inhibit tumor growth in vitro and in vivo. Cancer Res 2004; 64: 4875-4886.
-
(2004)
Cancer Res
, vol.64
, pp. 4875-4886
-
-
Spruce, B.A.1
Campbell, L.A.2
McTavish, N.3
Cooper, M.A.4
Appleyard, M.V.5
O'Neill, M.6
|