Mutation analysis of a recombinant NS replicon shows that influenza virus NS1 protein blocks the splicing and nucleo-cytoplasmic transport of its own viral mRNA

Nucleic Acids Research

Volumn 35, Issue 14, 2007, Pages 4573-4582

  Garaigorta, Urtzi ^a   Ortín, Juan ^a  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; MICROORGANISM PROTEIN; PROTEIN M2; PROTEIN NEP; PROTEIN NS1; PROTEIN NS2; RECOMBINANT RNA; RIBONUCLEOPROTEIN; RIBONUCLEOPROTEIN 7; RIBONUCLEOPROTEIN 8; RNA BINDING PROTEIN; RNA POLYMERASE II; SINGLE STRANDED RNA; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RNA;

AMINO TERMINAL SEQUENCE; ARTICLE; GENE MUTATION; HUMAN; HUMAN CELL; INFLUENZA VIRUS A; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA BINDING; RNA PROCESSING; RNA REPLICATION; RNA SPLICING; RNA TRANSCRIPTION; RNA TRANSPORT; VIRUS ACTIVATION; VIRUS ASSEMBLY; VIRUS TRANSCRIPTION;

ACTIVE TRANSPORT, CELL NUCLEUS; CELL LINE; CELL NUCLEUS; DNA MUTATIONAL ANALYSIS; DOWN-REGULATION; GENE EXPRESSION REGULATION, VIRAL; HUMANS; INFLUENZA A VIRUS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; REPLICON; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA SPLICING; RNA STABILITY; RNA, MESSENGER; RNA, VIRAL; TRANSCRIPTION, GENETIC; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE;

EID: 34547870537     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkm230     Document Type: Article

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