Temperature sensitive influenza a virus genome replication results from low thermal stability of polymerase-cRNA complexes

Virology Journal

Volumn 3, Issue , 2006, Pages

  Dalton, Rosa M ^a   Mullin, Anne E ^a   Amorim, Maria Joao ^a   Medcalf, Elizabeth ^a   Tiley, Laurence S ^a   Digard, Paul ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; RNA POLYMERASE; VIRUS ENZYME; VIRUS PROTEIN;

ARTICLE; BINDING ASSAY; BIOACCUMULATION; COMPARATIVE STUDY; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; ENZYME SYNTHESIS; GENE REPLICATION; HIGH TEMPERATURE; HOST RANGE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLUENZA VIRUS A; MUTANT; NONHUMAN; PROMOTER REGION; RNA ANALYSIS; RNA SEQUENCE; RNA SYNTHESIS; TEMPERATURE DEPENDENCE; TEMPERATURE SENSITIVITY; THERMOSTABILITY; TRANSCRIPTION REGULATION; VIRUS GENOME; WILD TYPE;

ANIMALS; BLOTTING, WESTERN; CELL LINE; GENOME, VIRAL; HEAT-SHOCK PROTEINS; HUMANS; INFLUENZA A VIRUS; PROMOTER REGIONS, GENETIC; RIBONUCLEOPROTEINS; RNA REPLICASE; RNA, VIRAL; RNA-BINDING PROTEINS; TEMPERATURE; TRANSCRIPTION, GENETIC; VIRAL PROTEINS; VIRUS REPLICATION;

AVES; INFLUENZA A VIRUS;

EID: 33748757153     PISSN: 1743422X     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-3-58     Document Type: Article

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