Rapid down-regulation of Ret following exposure of dopaminergic neurons to neurotoxins

Journal of Neurochemistry

Volumn 102, Issue 5, 2007, Pages 1606-1613

  Hirata, Yoko ^a   Kiuchi, Kazutoshi ^a  

^a GIFU UNIVERSITY   (Japan)

Author keywords

1 methyl 4 phenyl 1,2,3,6 tetrahydropyridine; PC12 cells; Ret; Rotenone

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; NEUROTOXIN; PROTEIN RET; ROTENONE; TYROSINE 3 MONOOXYGENASE; TYROSINE KINASE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL STRAIN; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; DOWN REGULATION; LIGAND BINDING; MALE; MOUSE; NERVE CELL DEGENERATION; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FAMILY; RAT;

ANIMALS; BRAIN; DOPAMINE; DOWN-REGULATION; MALE; MICE; MICE, INBRED C57BL; NERVE TISSUE PROTEINS; NEURONS; NEUROTOXINS; PC12 CELLS; PROTO-ONCOGENE PROTEINS C-RET; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TYROSINE 3-MONOOXYGENASE;

MAMMALIA; MUS; VERTEBRATA;

EID: 34547858138     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2007.04695.x     Document Type: Article

References (36)

1. Barroso-Chinea P., Cruz-Muros I., Aymerich M. S., Rodriguez-Diaz M., Afonso-Oramas D., Lanciego J. L. Gonzalez-Hernandez T. (2005) Striatal expression of GDNF and differential vulnerability of midbrain dopaminergic cells. Eur. J. Neurosci. 21, 1815 1827.
2. Bennett D. L., Boucher T. J., Armanini M. P., Poulsen K. T., Michael G. J., Priestley J. V., Phillips H. S., McMahon S. B. Shelton D. L. (2000) The glial cell line-derived neurotrophic factor family receptor components are differentially regulated within sensory neurons after nerve injury. J. Neurosci. 20, 427 437.
3. Betarbet R., Sherer T. B., MacKenzie G., Garcia-Osuna M., Panov A. V. Greenamyre J. T. (2000) Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat. Neurosci. 3, 1301 1306.
4. Betarbet R., Sherer T. B. Greenamyre J. T. (2002) Animal models of Parkinson's disease. Bioessays 24, 308 318.
5. Bordeaux M. C., Forcet C., Granger L., Corset V., Bidaud C., Billaud M., Bredesen D. E., Edery P. Mehlen P. (2000) The RET proto-oncogene induces apoptosis: a novel mechanism for Hirschsprung disease. EMBO J. 19, 4056 4063.
6. Bresjanac M. Antauer G. (2000) Reactive astrocytes of the quinolinic acid-lesioned rat striatum express GFRα1 as well as GDNF in vivo. Exp. Neurol. 164, 53 59.
7. 2-terminal protein kinases (JNKs): evidence for a divergence of the ERKs and JNKs pathways induced by Ret. Oncogene 16, 2435 2445.
8. Choi-Lundberg D. L., Lin Q., Chang Y. N., Chiang Y. L., Hay C. M., Mohajeri H., Davidson B. L. Bohn M. C. (1997) Dopaminergic neurons protected from degeneration by GDNF gene therapy. Science 275, 838 841.
9. Costantini L. C., Feinstein S. C., Radeke M. J. Snyder-Keller A. (1999) Compartmental expression of trkB receptor protein in the developing striatum. Neuroscience 89, 505 513.
10. Cristina N., Chatellard-Causse C., Manier M. Feuerstein C. (1995) GDNF: existence of a second transcript in the brain. Brain Res. Mol. Brain Res. 32, 354 357.
11. Durbec P., Marcos-Gutierrez C. V., Kilkenny C. et al. (1996) GDNF signalling through the Ret receptor tyrosine kinase. Nature 381, 789 793.
12. Golden J. P., Baloh R. H., Kotzbauer P. T., Lampe P. A., Osborne P. A., Milbrandt J. Johnson E. M. Jr. (1998) Expression of neurturin, GDNF, and their receptors in the adult mouse CNS. J. Comp. Neurol. 398, 139 150.
13. Hirata Y., Meguro T. Kiuchi K. (2006) Differential effect of nerve growth factor on dopaminergic neurotoxin-induced apoptosis. J. Neurochem. 99, 416 425.
14. Ho A., Gore A. C., Weickert C. S. Blum M. (1995) Glutamate regulation of GDNF gene expression in the striatum and primary striatal astrocytes. Neuroreport 6, 1454 1458.
15. Hyman C., Hofer M., Barde Y. A., Juhasz M., Yancopoulos G. D., Squinto S. P. Lindsay R. M. (1991) BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra. Nature 350, 230 232.
16. Inoue T., Tsui J., Wong N., Wong S. Y., Suzuki F. Kwok Y. N. (1999) Expression of glial cell line-derived neurotrophic factor and its mRNA in the nigrostriatal pathway following MPTP treatment. Brain Res. 826, 306 308.
17. Jing S., Wen D., Yu Y. et al. (1996) GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-α, a novel receptor for GDNF. Cell 85, 1113 1124.
18. Kopin I. J. Markey S. P. (1988) MPTP toxicity: implications for research in Parkinson's disease. Annu. Rev. Neurosci. 11, 81 96.
19. Kordower J. H., Emborg M. E., Bloch J. et al. (2000) Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science 290, 767 773.
20. Kramer E. R., Aron L., Ramakers G. M., Seitz S., Zhuang X., Beyer K., Smidt M. P. Klein R. (2007) Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system. PLoS Biol. 5, e39.
21. Krieglstein K. (2004) Factors promoting survival of mesencephalic dopaminergic neurons. Cell Tissue Res. 318, 73 80.
22. Li N., Ragheb K., Lawler G., Sturgis J., Rajwa B., Melendez J. A. Robinson J. P. (2003) Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. J. Biol. Chem. 278, 8516 8525.
23. Lin L. F., Doherty D. H., Lile J. D., Bektesh S. Collins F. (1993) GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260, 1130 1132.
24. Nakamura M., Ohta K., Hirokawa K., Fukushima M., Uchino M., Ando M. Tanaka H. (1996) Developmental and denervation changes in c-ret proto-oncogene expression in chick motoneurons. Brain Res. Mol. Brain Res. 39, 1 11.
25. Naveilhan P., ElShamy W. M. Ernfors P. (1997) Differential regulation of mRNAs for GDNF and its receptors Ret and GDNFR α after sciatic nerve lesion in the mouse. Eur. J. Neurosci. 9, 1450 1460.
26. Oppenheim R. W. (1991) Cell death during development of the nervous system. Annu. Rev. Neurosci. 14, 453 501.
27. Palfi S., Leventhal L., Chu Y., Ma S. Y., Emborg M., Bakay R., Deglon N., Hantraye P., Aebischer P. Kordower J. H. (2002) Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration. J. Neurosci. 22, 4942 4954.
28. Przedborski S., Jackson-Lewis V., Yokoyama R., Shibata T., Dawson V. L. Dawson T. M. (1996) Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity. Proc. Natl Acad. Sci. USA 93, 4565 4571.
29. Radad K., Rausch W. D. Gille G. (2006) Rotenone induces cell death in primary dopaminergic culture by increasing ROS production and inhibiting mitochondrial respiration. Neurochem. Int. 49, 379 386.
30. Smith A. D., Antion M., Zigmond M. J. Austin M. C. (2003) Effect of 6-hydroxydopamine on striatal GDNF and nigral GFRα1 and RET mRNAs in the adult rat. Brain Res. Mol. Brain Res. 117, 129 138.
31. Takahashi M., Buma Y. Taniguchi M. (1991) Identification of the ret proto-oncogene products in neuroblastoma and leukemia cells. Oncogene 6, 297 301.
32. Tomac A., Widenfalk J., Lin L. F., Kohno T., Ebendal T., Hoffer B. J. Olson L. (1995) Retrograde axonal transport of glial cell line-derived neurotrophic factor in the adult nigrostriatal system suggests a trophic role in the adult. Proc. Natl Acad. Sci. USA 92, 8274 8278.
33. Treanor J. J., Goodman L., de Sauvage F. et al. (1996) Characterization of a multicomponent receptor for GDNF. Nature 382, 80 83.
34. Trupp M., Arenas E., Fainzilber M., Nilsson A. S., Sieber B. A., Grigoriou M., Kilkenny C., Salazar-Grueso E., Pachnis V. Arumae U. (1996) Functional receptor for GDNF encoded by the c-ret proto-oncogene. Nature 381, 785 789.
35. Trupp M., Belluardo N., Funakoshi H. Ibanez C. F. (1997) Complementary and overlapping expression of glial cell line-derived neurotrophic factor (GDNF), c-ret proto-oncogene, and GDNF receptor-α indicates multiple mechanisms of trophic actions in the adult rat CNS. J. Neurosci. 17, 3554 3567.
36. Wang K. K. (2000) Calpain and caspase: can you tell the difference? Trends Neurosci. 23, 20 26.