Neurotoxic mechanisms of electrophilic type-2 Alkenes: Soft-soft interactions described by quantum mechanical parameters

Toxicological Sciences

Volumn 98, Issue 2, 2007, Pages 561-570

  LoPachin, Richard M ^a   Gavin, Terrence ^b   Geohagen, Brian C ^a   Das, Soma ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b IONA COLLEGE   (United States)

Author keywords

Acrolein; Acrylamide; Adduct formation; Distal axonopathy; Nerve terminal; Neurotoxicity; Type 2 alkenes

Indexed keywords

ACETYLCYSTEINE; ACROLEIN; ACRYLAMIDE; ACRYLIC ACID METHYL ESTER; ALKENE DERIVATIVE; CYSTEINE DERIVATIVE; KETONE DERIVATIVE; LYSINE DERIVATIVE; N ETHYLMALEIMIDE; THIOL DERIVATIVE; THIOL GROUP;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRON TRANSPORT; HARDNESS; MOLECULAR INTERACTION; NEUROTOXICITY; NONHUMAN; PROTEIN INTERACTION; PROTEIN TARGETING; QUANTUM MECHANICS; RAT; SYNAPTOSOME;

1-PROPANOL; ACROLEIN; ACRYLAMIDE; ACRYLATES; ALKENES; ANIMALS; BUTANONES; CORPUS STRIATUM; CYSTEINE; DOPAMINE; ETHYLMALEIMIDE; MALE; NEUROTOXICITY SYNDROMES; PROPANOLS; QUANTUM THEORY; RATS; RATS, SPRAGUE-DAWLEY; SYNAPTOSOMES;

EID: 34547851659     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm127     Document Type: Article

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