메뉴 건너뛰기




Volumn 13, Issue 5, 2007, Pages 461-467

Immunohistochemical detection of phosphorylated Akt, PI3K, and PTEN in ameloblastic tumors

Author keywords

Akt; Ameloblastoma; PI3K; PTEN; Tooth germ

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B;

EID: 34547842827     PISSN: 1354523X     EISSN: 16010825     Source Type: Journal    
DOI: 10.1111/j.1601-0825.2006.01321.x     Document Type: Article
Times cited : (26)

References (39)
  • 1
    • 27844445642 scopus 로고    scopus 로고
    • Perturbations of the AKT signaling pathway in human cancer
    • Altomare DA, Testa JR (2005). Perturbations of the AKT signaling pathway in human cancer. Oncogene 24 : 7455 7464.
    • (2005) Oncogene , vol.24 , pp. 7455-7464
    • Altomare, D.A.1    Testa, J.R.2
  • 2
    • 0026010958 scopus 로고
    • Expression of IGF-I and -II mRNA in the brain and craniofacial region of the rat fetus
    • Ayer-le Lievre C, Stahlbom PA, Sara VR (1991). Expression of IGF-I and -II mRNA in the brain and craniofacial region of the rat fetus. Development 111 : 105 115.
    • (1991) Development , vol.111 , pp. 105-115
    • Ayer-Le Lievre, C.1    Stahlbom, P.A.2    Sara, V.R.3
  • 3
    • 0035902180 scopus 로고    scopus 로고
    • Oncogenic kinase signalling
    • Blume-Jensen P, Hunter T (2001). Oncogenic kinase signalling. Nature 411 : 355 365.
    • (2001) Nature , vol.411 , pp. 355-365
    • Blume-Jensen, P.1    Hunter, T.2
  • 4
    • 0026486379 scopus 로고
    • Immunolocalization of acidic and basic fibroblast growth factors during mouse odontogenesis
    • Cam Y, Neumann MR, Oliver L et al. (1992). Immunolocalization of acidic and basic fibroblast growth factors during mouse odontogenesis. Int J Dev Biol 36 : 381 389.
    • (1992) Int J Dev Biol , vol.36 , pp. 381-389
    • Cam, Y.1    Neumann, M.R.2    Oliver, L.3
  • 5
    • 0000440912 scopus 로고    scopus 로고
    • Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase
    • Chang HW, Aoki M, Fruman D et al. (1997). Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase. Science 276 : 1848 1850.
    • (1997) Science , vol.276 , pp. 1848-1850
    • Chang, H.W.1    Aoki, M.2    Fruman, D.3
  • 6
    • 0035448879 scopus 로고    scopus 로고
    • Growth retardation and increased apoptosis in mice with homozygous disruption of the akt1 gene
    • Chen WS, Xu PZ, Gottlob K et al. (2001). Growth retardation and increased apoptosis in mice with homozygous disruption of the akt1 gene. Genes Dev 15 : 2203 2208.
    • (2001) Genes Dev , vol.15 , pp. 2203-2208
    • Chen, W.S.1    Xu, P.Z.2    Gottlob, K.3
  • 7
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: A play in three Akts
    • Datta SR, Brunet A, Greenberg ME (1999). Cellular survival: a play in three Akts. Genes Dev 13 : 2905 2927.
    • (1999) Genes Dev , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 8
    • 0031870959 scopus 로고    scopus 로고
    • Pten is essential for embryonic development and tumour suppression
    • Di Cristofano A, Pesce B, Cordon-Cardo C et al. (1998). Pten is essential for embryonic development and tumour suppression. Nat Genet 19 : 348 355.
    • (1998) Nat Genet , vol.19 , pp. 348-355
    • Di Cristofano, A.1    Pesce, B.2    Cordon-Cardo, C.3
  • 9
    • 0033556333 scopus 로고    scopus 로고
    • Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85α
    • Fruman DA, Snapper SB, Yballe CM et al. (1999). Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85α. Science 283 : 393 397.
    • (1999) Science , vol.283 , pp. 393-397
    • Fruman, D.A.1    Snapper, S.B.2    Yballe, C.M.3
  • 10
    • 0027380546 scopus 로고
    • EGF receptor and its ligands, EGF and TGF-alpha, in developing and neoplastic human odontogenic tissues
    • Heikinheimo K, Voutilainen R, Happonen RP et al. (1993). EGF receptor and its ligands, EGF and TGF-alpha, in developing and neoplastic human odontogenic tissues. Int J Dev Biol 37 : 387 396.
    • (1993) Int J Dev Biol , vol.37 , pp. 387-396
    • Heikinheimo, K.1    Voutilainen, R.2    Happonen, R.P.3
  • 11
    • 0036704481 scopus 로고    scopus 로고
    • Gene expression profiling of ameloblastoma and human tooth germ by means of a cDNA microarray
    • Heikinheimo K, Jee KJ, Niini T et al. (2002). Gene expression profiling of ameloblastoma and human tooth germ by means of a cDNA microarray. J Dent Res 81 : 525 530.
    • (2002) J Dent Res , vol.81 , pp. 525-530
    • Heikinheimo, K.1    Jee, K.J.2    Niini, T.3
  • 12
    • 15244354009 scopus 로고    scopus 로고
    • TNFα played a role in induction of Akt and MAPK signals in ameloblastoma
    • Hendarmin L, Sandra F, Nakao Y et al. (2005). TNFα played a role in induction of Akt and MAPK signals in ameloblastoma. Oral Oncol 41 : 375 382.
    • (2005) Oral Oncol , vol.41 , pp. 375-382
    • Hendarmin, L.1    Sandra, F.2    Nakao, Y.3
  • 13
    • 0032472913 scopus 로고    scopus 로고
    • Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3-kinase
    • Jimenez C, Jones DR, Rodriguez-Viciana P et al. (1998). Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3-kinase. EMBO J 17 : 743 753.
    • (1998) EMBO J , vol.17 , pp. 743-753
    • Jimenez, C.1    Jones, D.R.2    Rodriguez-Viciana, P.3
  • 14
    • 33645237170 scopus 로고    scopus 로고
    • Molecular pathology of odontogenic tumors
    • Kumamoto H (2006). Molecular pathology of odontogenic tumors. J Oral Pathol Med 35 : 65 74.
    • (2006) J Oral Pathol Med , vol.35 , pp. 65-74
    • Kumamoto, H.1
  • 15
    • 17144391880 scopus 로고    scopus 로고
    • Expression of tumor necrosis factor α, TNF-related apoptosis-inducing ligand, and their associated molecules in ameloblastomas
    • Kumamoto H, Ooya K (2005a). Expression of tumor necrosis factor α, TNF-related apoptosis-inducing ligand, and their associated molecules in ameloblastomas. J Oral Pathol Med 34 : 287 294.
    • (2005) J Oral Pathol Med , vol.34 , pp. 287-294
    • Kumamoto, H.1    Ooya, K.2
  • 16
    • 25144489570 scopus 로고    scopus 로고
    • Detection of mitochondria-mediated apoptosis signaling molecules in ameloblastomas
    • Kumamoto H, Ooya K (2005b). Detection of mitochondria-mediated apoptosis signaling molecules in ameloblastomas. J Oral Pathol Med 34 : 565 572.
    • (2005) J Oral Pathol Med , vol.34 , pp. 565-572
    • Kumamoto, H.1    Ooya, K.2
  • 17
    • 0034914296 scopus 로고    scopus 로고
    • Detection of cell cycle-related factors in ameloblastomas
    • Kumamoto H, Kimi K, Ooya K (2001). Detection of cell cycle-related factors in ameloblastomas. J Oral Pathol Med 30 : 309 315.
    • (2001) J Oral Pathol Med , vol.30 , pp. 309-315
    • Kumamoto, H.1    Kimi, K.2    Ooya, K.3
  • 18
    • 0036786808 scopus 로고    scopus 로고
    • Immunohistochemical detection of hepatocyte growth factor, transforming growth factor-β and their receptors in epithelial odontogenic tumors
    • Kumamoto H, Yoshida M, Ooya K (2002). Immunohistochemical detection of hepatocyte growth factor, transforming growth factor-β and their receptors in epithelial odontogenic tumors. J Oral Pathol Med 31 : 539 548.
    • (2002) J Oral Pathol Med , vol.31 , pp. 539-548
    • Kumamoto, H.1    Yoshida, M.2    Ooya, K.3
  • 19
    • 2342486778 scopus 로고    scopus 로고
    • P53 gene status and expression of p53, MDM2, and p14ARF proteins in ameloblastomas
    • Kumamoto H, Izutsu T, Ohki K et al. (2004a). p53 gene status and expression of p53, MDM2, and p14ARF proteins in ameloblastomas. J Oral Pathol Med 33 : 292 299.
    • (2004) J Oral Pathol Med , vol.33 , pp. 292-299
    • Kumamoto, H.1    Izutsu, T.2    Ohki, K.3
  • 20
    • 3142703561 scopus 로고    scopus 로고
    • K-Ras gene status and expression of Ras/mitogen-activated protein kinase (MAPK) signaling molecules in ameloblastomas
    • Kumamoto H, Takahashi N, Ooya K (2004b). K-Ras gene status and expression of Ras/mitogen-activated protein kinase (MAPK) signaling molecules in ameloblastomas. J Oral Pathol Med 33 : 360 367.
    • (2004) J Oral Pathol Med , vol.33 , pp. 360-367
    • Kumamoto, H.1    Takahashi, N.2    Ooya, K.3
  • 21
    • 0030936323 scopus 로고    scopus 로고
    • PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
    • Li J, Yen C, Liaw D et al. (1997). PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 275 : 1943 1947.
    • (1997) Science , vol.275 , pp. 1943-1947
    • Li, J.1    Yen, C.2    Liaw, D.3
  • 22
    • 0031004088 scopus 로고    scopus 로고
    • Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
    • Liaw D, Marsh DJ, Li J et al. (1997). Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat Genet 16 : 64 67.
    • (1997) Nat Genet , vol.16 , pp. 64-67
    • Liaw, D.1    Marsh, D.J.2    Li, J.3
  • 23
    • 0031203265 scopus 로고    scopus 로고
    • Germline mutations in PTEN are present in Bannayan-Zonana syndrome
    • Marsh DJ, Dahia PL, Zheng Z et al. (1997). Germline mutations in PTEN are present in Bannayan-Zonana syndrome. Nat Genet 16 : 333 334.
    • (1997) Nat Genet , vol.16 , pp. 333-334
    • Marsh, D.J.1    Dahia, P.L.2    Zheng, Z.3
  • 24
    • 0036710512 scopus 로고    scopus 로고
    • The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network
    • Mayo LD, Donner DB (2002). The PTEN, Mdm2, p53 tumor suppressor- oncoprotein network. Trends Biochem Sci 27 : 462 677.
    • (2002) Trends Biochem Sci , vol.27 , pp. 462-677
    • Mayo, L.D.1    Donner, D.B.2
  • 25
    • 4344675306 scopus 로고    scopus 로고
    • Allelic loss of tumor suppressor genes in ameloblastic tumors
    • Nodit L, Barnes L, Childers E et al. (2004). Allelic loss of tumor suppressor genes in ameloblastic tumors. Mod Pathol 17 : 1062 1067.
    • (2004) Mod Pathol , vol.17 , pp. 1062-1067
    • Nodit, L.1    Barnes, L.2    Childers, E.3
  • 26
    • 33745042414 scopus 로고    scopus 로고
    • Odontogenic tumours
    • In: Barnes, L., Eveson, J.W., Reichart, P.A., Sidransky, D., eds. Pathology & Genetics. Lyon: IARC Press, pp.
    • Philipsen HP, Reichart PA, Slootweg PJ et al. (2005). Odontogenic tumours. In : Barnes L, Eveson JW, Reichart PA, Sidransky D, eds. WHO classification of head and neck tumours. Pathology & Genetics. Lyon : IARC Press, pp. 283 327.
    • (2005) WHO Classification of Head and Neck Tumours. , pp. 283-327
    • Philipsen, H.P.1    Reichart, P.A.2    Slootweg, P.J.3
  • 27
    • 11144358645 scopus 로고    scopus 로고
    • High frequency of mutations of the PIK3CA gene in human cancers
    • Samuels Y, Wang Z, Bardelli A et al. (2004). High frequency of mutations of the PIK3CA gene in human cancers. Science 304 : 554.
    • (2004) Science , vol.304 , pp. 554
    • Samuels, Y.1    Wang, Z.2    Bardelli, A.3
  • 28
    • 0036180587 scopus 로고    scopus 로고
    • The role of MDM2 in the proliferative activity of ameloblastoma
    • Sandra F, Nakamura N, Kanematsu T et al. (2002). The role of MDM2 in the proliferative activity of ameloblastoma. Oral Oncol 38 : 153 157.
    • (2002) Oral Oncol , vol.38 , pp. 153-157
    • Sandra, F.1    Nakamura, N.2    Kanematsu, T.3
  • 29
    • 20444454718 scopus 로고    scopus 로고
    • Ameloblastoma induces osteoclastogenesis: A possible role of ameloblastoma in expanding in the bone
    • Sandra F, Hendarmin L, Kukita T et al. (2005). Ameloblastoma induces osteoclastogenesis: a possible role of ameloblastoma in expanding in the bone. Oral Oncol 41 : 637 644.
    • (2005) Oral Oncol , vol.41 , pp. 637-644
    • Sandra, F.1    Hendarmin, L.2    Kukita, T.3
  • 31
    • 0032590011 scopus 로고    scopus 로고
    • PIK3CA is implicated as an oncogene in ovarian cancer
    • Shayesteh L, Lu Y, Kuo WL et al. (1999). PIK3CA is implicated as an oncogene in ovarian cancer. Nat Genet 21 : 99 102.
    • (1999) Nat Genet , vol.21 , pp. 99-102
    • Shayesteh, L.1    Lu, Y.2    Kuo, W.L.3
  • 32
    • 0024338138 scopus 로고
    • Localization of epidermal growth factor precursor in tooth and lung during embryonic mouse development
    • Snead ML, Luo W, Oliver P et al. (1989). Localization of epidermal growth factor precursor in tooth and lung during embryonic mouse development. Dev Biol 134 : 420 429.
    • (1989) Dev Biol , vol.134 , pp. 420-429
    • Snead, M.L.1    Luo, W.2    Oliver, P.3
  • 33
    • 0034945433 scopus 로고    scopus 로고
    • Immunohistochemical localization of fibroblast growth factors FGF-1 and FGF-2, and receptors FGFR2 and FGFR3 in the epithelium of human odontogenic cysts and tumors
    • So F, Daley TD, Jackson L, Wysocki GP (2001). Immunohistochemical localization of fibroblast growth factors FGF-1 and FGF-2, and receptors FGFR2 and FGFR3 in the epithelium of human odontogenic cysts and tumors. J Oral Pathol Med 30 : 428 433.
    • (2001) J Oral Pathol Med , vol.30 , pp. 428-433
    • So, F.1    Daley, T.D.2    Jackson, L.3    Wysocki, G.P.4
  • 34
    • 0001582482 scopus 로고
    • Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: Amplification of AKT1 in a primary human gastric adenocarcinoma
    • Staal SP (1987). Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma. Proc Natl Acad Sci U S A 84 : 5034 5037.
    • (1987) Proc Natl Acad Sci U S a , vol.84 , pp. 5034-5037
    • Staal, S.P.1
  • 35
    • 0032475861 scopus 로고    scopus 로고
    • Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
    • Stambolic V, Suzuki A, de la Pompa JL et al. (1998). Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell 95 : 29 39.
    • (1998) Cell , vol.95 , pp. 29-39
    • Stambolic, V.1    Suzuki, A.2    De La Pompa, J.L.3
  • 36
    • 15844364380 scopus 로고    scopus 로고
    • Hepatocyte growth factor is involved in the morphogenesis of tooth germ in murine molars
    • Tabata MJ, Kim K, Liu JG et al. (1996). Hepatocyte growth factor is involved in the morphogenesis of tooth germ in murine molars. Development 122 : 1243 1251.
    • (1996) Development , vol.122 , pp. 1243-1251
    • Tabata, M.J.1    Kim, K.2    Liu, J.G.3
  • 37
    • 0032909703 scopus 로고    scopus 로고
    • Increased insulin sensitivity and hypoglycaemia in mice lacking the p85α subunit of phosphoinositide 3-kinase
    • Terauchi Y, Tsuji Y, Satoh S et al. (1999). Increased insulin sensitivity and hypoglycaemia in mice lacking the p85α subunit of phosphoinositide 3-kinase. Nat Genet 21 : 230 235.
    • (1999) Nat Genet , vol.21 , pp. 230-235
    • Terauchi, Y.1    Tsuji, Y.2    Satoh, S.3
  • 38
    • 0023897684 scopus 로고
    • Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate
    • Whitman M, Downes CP, Keeler M et al. (1988). Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate. Nature 332 : 644 646.
    • (1988) Nature , vol.332 , pp. 644-646
    • Whitman, M.1    Downes, C.P.2    Keeler, M.3
  • 39
    • 0028963084 scopus 로고
    • Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor
    • Yao R, Cooper GM (1995). Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor. Science 267 : 2003 2006.
    • (1995) Science , vol.267 , pp. 2003-2006
    • Yao, R.1    Cooper, G.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.