Finding Plk3

Cell Cycle

Volumn 6, Issue 11, 2007, Pages 1314-1318

  Zimmerman, Wendy C ^a   Erikson, Raymond L ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

Cell cycle; Nucleolus; Plk1; Plk3

Indexed keywords

POLO LIKE KINASE 1; POLO LIKE KINASE 2; POLO LIKE KINASE 3; CELL CYCLE PROTEIN; CYCLIN E; ONCOPROTEIN; PLK3 PROTEIN, HUMAN; PLK3 PROTEIN, MOUSE; POLO-LIKE KINASE 1; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; HUMAN; MITOSIS; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; NUCLEOLUS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; ANIMAL; CELL CYCLE; CELL LINE; ENZYME INDUCTION; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; IMMEDIATE EARLY GENE; ISOLATION AND PURIFICATION; MAMMAL; METABOLISM; MOUSE; MOUSE MUTANT; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; VERTEBRATE;

VERTEBRATA;

ANIMALS; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE; CELL NUCLEOLUS; CYCLIN E; ENZYME INDUCTION; G1 PHASE; GENES, IMMEDIATE-EARLY; HUMANS; MAMMALS; MICE; MICE, KNOCKOUT; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; S PHASE; SUBSTRATE SPECIFICITY; VERTEBRATES;

EID: 34547673620     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.6.11.4275     Document Type: Review

References (49)

1. Lee KS, Park JE, Asano S, Park CJ. Yeast polo-like kinases: Functionally conserved multitask mitotic regulators. Oncogene 2005; 24:217-29.
2. Glover DM. Polo kinase and progression through M phase in Drosophila: A perspective from the spindle poles. Oncogene 2005; 24:230-7.
3. Leung GC, Hudson JW, Kozarova A, Davidson A, Dennis JW, Sicheri F. The Sak polo-box comprises a structural domain sufficient for mitotic subcellular localization. Nat Struct Biol 2002; 9:719-24.
4. Zimmerman WC, Erikson RL. Polo-like kinase 3 is required for entry into S phase. Proc Natl Acad Sci USA 2007; 104:1847-52.
5. 1 phase polo-like kinase that is inhibited by the calcium- and integrin-binding protein CIB. Mol Cancer Res 2003; 1:376-84.
6. Lee KS, Grenfell TZ, Yarm FR, Erikson RL. Mutation of the polo-box disrupts localization and mitotic functions of the mammalian polo kinase Plk. Proc Natl Acad Sci USA 1998; 95:9301-6.
7. Elia AE, Rellos P, Haire LF, Chao JW, Ivins FJ, Hoepker K, Mohammad D, Cantley LC, Smerdon SJ, Yaffe MB. The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain. Cell 2003; 115:83-95.
8. Elia AE, Cantley LC, Yaffe MB. Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates. Science 2003; 299:1228-31.
9. Gumireddy K, Reddy MV, Cosenza SC, Boomi Nathan R, Baker SJ, Papathi N, Jiang J, Holland J, Reddy EP. ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent. Cancer Cell 2005; 7:275-86.
10. Xie S, Wu H, Wang Q, Cogswell JP, Husain I, Conn C, Stambrook P, Jhanwar-Uniyal M, Dai W. Plk3 functionally links DNA damage to cell cycle arrest and apoptosis at least in part via the p53 pathway. J Biol Chem 2001; 276:43305-12.
11. Barr FA, Sillje HH, Nigg EA. Polo-like kinases and the orchestration of cell division. Nat Rev Mol Cell Biol 2004; 5:429-40.
12. van Vugt MA, Medema RH. Getting in and out of mitosis with Polo-like kinase-1. Oncogene 2005; 24:2844-59.
13. Hernandez-Verdun D, Roussel P, Gebrane-Younes J. Emerging concepts of nucleolar assembly. J Cell Sci 2002; 115:2265-70.
14. Jiang N, Wang X, Jhanwar-Uniyal M, Darzynkiewicz Z, Dai W. Polo-box domain of PLK3 functions as a centrosome localization signal, over-expression of which causes mitotic arrest, cytokinesis defects, and apoptosis. J Biol Chem 2006.
15. Conn CW, Hennigan RF, Dai W, Sanchez Y, Stambrook PJ. Incomplete cytokinesis and induction of apoptosis by overexpression of the mammalian polo-like kinase, Plk3. Cancer Res 2000; 60:6826-31.
16. Jang YJ, Lin CY, Ma S, Erikson RL. Functional studies on the role of the C-terminal domain of mammalian polo-like kinase. Proc Natl Acad Sci USA 2002; 99:1984-9.
17. Lindon C, Pines J. Ordered proteolysis in anaphase inactivates Plk1 to contribute to proper mitotic exit in human cells. J Cell Biol 2004; 164:233-41.
18. Donohue PJ, Alberts GF, Guo Y, Winkles JA. Identification by targeted differential display of an immediate early gene encoding a putative serine/threonine kinase. J Biol Chem 1995; 270:10351-7.
19. Li B, Ouyang B, Pan H, Reissmann PT, Slamon DJ, Arceci R, Lu L, Dai W. Prk, a cytokine-inducible human protein serine/threonine kinase whose expression appears to be down-regulated in lung carcinomas. J Biol Chem 1996; 271:19402-8.
20. Anger M, Kues WA, Klima J, Mielenz M, Kubelka M, Motlik J, Esner M, Dvorak P, Carnwath JW, Niemann H. Cell cycle dependent expression of Plk1 in synchronized porcine fetal fibroblasts. Mol Reprod Dev 2003; 65:245-53.
21. Bahassi el M, Conn CW, Myer DL, Hennigan RF, McGowan CH, Sanchez Y, Stambrook PJ. Mammalian Polo-like kinase 3 (Plk3) is a multifunctional protein involved in stress response pathways. Oncogene 2002; 21:6633-40.
22. Chase D, Feng Y, Hanshew B, Winkles JA, Longo DL, Ferris DK. Expression and phosphorylation of fibroblast-growth-factor-inducible kinase (Fnk) during cell-cycle progression. Biochem J 1998; 333(Pt 3):655-60.
23. Dignam JD, Lebovitz RM, Roeder RG. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 1983; 11:1475-89.
24. Xie S, Wang Q, Ruan Q, Liu T, Jhanwar-Uniyal M, Guan K, Dai W. MEK1-induced Golgi dynamics during cell cycle progression is partly mediated by Polo-like kinase-3. Oncogene 2004; 23:3822-9.
25. Xie S, Wang Q, Wu H, Cogswell J, Lu L, Jhanwar-Uniyal M, Dai W. Reactive oxygen species-induced phosphorylation of p53 on serine 20 is mediated in part by polo-like kinase-3. J Biol Chem 2001; 276:36194-9.
26. Wang Q, Xie S, Chen J, Fukasawa K, Naik U, Traganos F, Darzynkiewicz Z, Jhanwar-Uniyal M, Dai W. Cell cycle arrest and apoptosis induced by human Polo-like kinase 3 is mediated through perturbation of microtubule integrity. Mol Cell Biol 2002; 22:3450-9.
27. Myer DL, Bahassi el M, Stambrook PJ. The Plk3-Cdc25 circuit. Oncogene 2005; 24:299-305.
28. Geng Y, Yu Q, Das M, Schneider JE, Bhattacharya S, Rideout WM, Bronson RT, Gardner H, Sicinski P. Cyclin E ablation in the mouse. Cell 2003; 114:431-43.
29. Wiest J, Clark AM, Dai W. Intron/exon organization and polymorphisms of the PLK3/PRK gene in human lung carcinoma cell lines. Genes Chromosomes Cancer 2001; 32:384-9.
30. Syed N, Smith P, Sullivan A, Spender LC, Dyer M, Karran L, O'Nions J, Allday M, Hoffmann I, Crawford D, Griffin B, Farrell PJ, Crook T. Transcriptional silencing of Polo-like kinase 2 (SNK/PLK2) is a frequent event in B-cell malignancies. Blood 2006; 107:250-6.
31. Sjoblom T, Jones S, Wood LD, Parsons DW, Lin J, Barber TD, Mandelker D, Leary RJ, Ptak J, Silliman N, Szabo S, Buckhaults P, Farrell C, Meeh P, Markowitz SD, Willis J, Dawson D, Willson JK, Gazdar AF, Hartigan J, Wu L, Liu C, Parmigiani G, Park BH, Bachman KE, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE. The consensus coding sequences of human breast and colorectal cancers. Science 2006; 314:268-74.
32. Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O'Meara S, Vastrik I, Schmidt EE, Avis T, Barthorpe S, Bhamra G, Buck G, Choudhury B, Clements J, Cole J, Dicks E, Forbes S, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jenkinson A, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Tofts C, Varian J, Webb T, West S, Widaa S, Yates A, Cahill DP, Louis DN, Goldstraw P, Nicholson AG, Brasseur F, Looijenga L, Weber BL, Chiew YE, DeFazio A, Greaves MF, Green AR, Campbell P, Birney E, Easton DF, Chenevix-Trench G, Tan MH, Khoo SK, Teh BT, Yuen ST, Leung SY, Wooster R, Futreal PA, Stratton MR. Patterns of somatic mutation in human cancer genomes. Nature 2007; 446:153-8.
33. Levchenko A, Bruck J, Sternberg PW. Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties. Proc Natl Acad Sci USA 2000; 97:5818-23.
34. Morrison DK, Davis RJ. Regulation of MAP kinase signaling modules by scaffold proteins in mammals. Annu Rev Cell Dev Biol 2003; 19:91-118.
35. Diehl JA, Cheng M, Roussel MF, Sherr CJ. Glycogen synthase kinase -3beta regulates cyclin D1 proteolysis and subcellular localization. Genes Dev 1998; 12:3499-511.
36. Juan G, Cordon-Cardo C. Intranuclear compartmentalization of cyclin E during the cell cycle: Disruption of the nucleoplasm-nucleolar shuttling of cyclin E in bladder cancer. Cancer Res 2001; 61:1220-6.
37. Cazzalini O, Perucca P, Valsecchi F, Stivala LA, Bianchi L, Vannini V, Prosperi E. Intracellular localization of the cyclin-dependent kinase inhibitor p21CDKN1A-GFP fusion protein during cell cycle arrest. Histochem Cell Biol 2004; 121:377-81.
38. Kim SH, Li C, Maller JL. A maternal form of the Phosphatase Cdc25A regulates early embryonic cycles in Xenopus laevis. Dev Biol 1999; 212:381-91.
39. Welcker M, Orian A, Grim JA, Eisenman RN, Clurman BE. A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size. Curr Biol 2004; 14:1852-7.
40. Mekhail K, Khacho M, Carrigan A, Hache RR, Gunaratnam L, Lee S. Regulation of ubiquitin ligase dynamics by the nucleolus. J Cell Biol 2005; 170:733-44.
41. Cerutti L, Simanis V. Controlling the end of the cell cycle. Curr Opin Genet Dev 2000; 10:65-9.
42. Klibanov SA, O'Hagan HM, Ljungman M. Accumulation of soluble and nucleolar-associated p53 proteins following cellular stress. J Cell Sci 2001; 114:1867-73.
43. Argentini M, Barboule N, Wasylyk B. The contribution of the RING finger domain of MDM2 to cell cycle progression. Oncogene 2000; 19:3849-57.
44. Rogalsky V, Todorov G, Moran D. Translocation of retinoblastoma protein associated with tumor cell growth inhibition. Biochemi Biophys Res Commun 1993; 192:1139-46.
45. Zini N, Trimarchi C, Claudio PP, Stiegler P, Marinelli F, Maltarello MC, La Sala D, De Falco G, Russo G, Ammirati G, Maraldi NM, Giordano A, Cinti C. pRb2/p130 and p107 control cell growth by multiple strategies and in association with different compartments within the nucleus. J Cell Physiol 2001; 189:34-44.
46. Green C, Chatterjee R, McGarrigle HH, Ahmed F, Thomas NS. p107 is active in the nucleolus in non-dividing human granulosa lutein cells. J Mol Endocrinol 2000; 25:275-86.
47. Wsierska-Gadek J, Horky M. How the nucleolar sequestration of p53 protein or its interplayers contributes to its (re)-activation. Ann NY Acad Sci 2003; 1010:266-72.
48. Rizos H, Darmanian AP, Mann GJ, Kefford RF. Two arginine rich domains in the p14ARF tumour suppressor mediate nucleolar localization. Oncogene 2000; 19:2978-85.
49. Taniguchi E, Toyoshima-Morimoto F, Nishida E. Nuclear translocation of plk1 mediated by its bipartite nuclear localization signal. J Biol Chem 2002; 277:48884-8.