Quantification of drugs in plasma without primary reference standards by liquid chromatography-chemiluminescence nitrogen detection: Application to tramadol metabolite ratios

Therapeutic Drug Monitoring

Volumn 29, Issue 4, 2007, Pages 423-428

  Ojanperä, Suvi ^a,b   Rasanen, Ilpo ^a   Sistonen, Johanna ^a   Pelander, Anna ^a   Vuori, Erkki ^a   Ojanperä, Ilkka ^a  

^a Department of Forensic Medicine ^*  (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Extraction recovery; LC CLND; Metabolite ratio; Therapeutic drug monitoring; Tramadol

Indexed keywords

ALCOHOL DERIVATIVE; CAFFEINE; DRUG METABOLITE; NORTRAMADOL; O NORTRAMADOL; OPIATE; TRAMADOL; UNCLASSIFIED DRUG;

ARTICLE; BLOOD SAMPLING; CALIBRATION; CHEMOLUMINESCENCE; CHEMOLUMINESCENCE NITROGEN DETECTION; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG BLOOD LEVEL; FEASIBILITY STUDY; GAS CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; INTERMETHOD COMPARISON; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MASS SPECTROMETRY; NITROGEN DETECTOR; NORMAL HUMAN; PH; PHARMACOGENETICS; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; STANDARD;

ANALGESICS, OPIOID; CHEMILUMINESCENT MEASUREMENTS; CHROMATOGRAPHY, LIQUID; CYTOCHROME P-450 CYP2D6; FEASIBILITY STUDIES; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; NITROGEN; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TRAMADOL;

EID: 34547655753     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/FTD.0b013e318074de97     Document Type: Article

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