Quantitation of drug metabolites in the absence of pure metabolite standards by high-performance liquid chromatography coupled with a chemiluminescence nitrogen detector and mass spectrometer

Rapid Communications in Mass Spectrometry

Volumn 18, Issue 15, 2004, Pages 1681-1685

  Deng, Yuzhong ^a   Wu, Jing Tao ^a,b   Zhang, Hongwei ^a   Olah, Timothy V ^a  

^a BRISTOL MYERS SQUIBB   (United States)

^b MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; BODY FLUIDS; CHEMILUMINESCENCE; DRUG PRODUCTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; METABOLITES;

ANALYTE RESPONSE; DEVELOPMENT PROCESS; DRUG DEVELOPMENT; DRUG DISCOVERY PROCESS; DRUG METABOLITES; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; OXAZEPAM; QUANTITATIVE INFORMATION; RESPONSE FACTOR; SMALL VARIATIONS;

NITROGEN;

DRUG METABOLITE; OXAZEPAM; TEMAZEPAM;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; CHEMOLUMINESCENCE; CHROMATOGRAPHY; DOG; DRUG METABOLISM; DRUG URINE LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN;

EID: 3543100262     PISSN: 09514198     EISSN: None     Source Type: Journal    
DOI: 10.1002/rcm.1540     Document Type: Article

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