Plasticity of fission yeast CENP-A chromatin driven by relative levels of histone H3 and H4

PLoS Genetics

Volumn 3, Issue 7, 2007, Pages 1264-1274

  Castillo, Araceli G ^a   Mellonea, Barbara G ^a,b   Partridgeb, Janet F ^a,c   Richardsonc, William ^a,d   Hamilton, Georgina L ^a   Allshire, Robin C ^a   Pidoux, Alison L ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^d MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CENTROMERE PROTEIN A; DNA; HISTONE H3; HISTONE H4; NUCLEAR PROTEIN; AUTOANTIGEN; FUNGAL PROTEIN; HISTONE; NONHISTONE PROTEIN; PRIMER DNA;

ARTICLE; CENTROMERE; CHROMATIN; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMOSOME SEGREGATION; CORRELATION ANALYSIS; DNA SEQUENCE; GENE SEQUENCE; GENE SILENCING; MARKER GENE; MITOSIS; NONHUMAN; YEAST; BIOLOGICAL MODEL; CHEMISTRY; GENOME; METABOLISM; MITOSIS SPINDLE; PLASMID; PROTEIN TERTIARY STRUCTURE; SCHIZOSACCHAROMYCES;

SCHIZOSACCHAROMYCETACEAE;

AUTOANTIGENS; CENTROMERE; CHROMATIN; CHROMOSOMAL PROTEINS, NON-HISTONE; DNA; DNA PRIMERS; FUNGAL PROTEINS; GENOME, FUNGAL; HISTONES; KINETOCHORES; MITOTIC SPINDLE APPARATUS; MODELS, BIOLOGICAL; PLASMIDS; PROTEIN STRUCTURE, TERTIARY; SCHIZOSACCHAROMYCES;

EID: 34547639766     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.0030121     Document Type: Article

References (59)

1. Cleveland DW, Mao Y, Sullivan KF (2003) Centromeres and kinetochores: From epigenetics to mitotic checkpoint signaling. Cell 112: 407-421.
2. Sullivan BA, Blower MD, Karpen GH (2001) Determining centromere identity: Cyclical stories and forking paths. Nat Rev Genet 2: 584-596.
3. Ahmad K, Henikoff S (2002) The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly. Mol Cell 9: 1191-1200.
4. McKittrick E, Gafken PR, Ahmad K, Henikoff S (2004) Histone H3.3 is enriched in covalent modifications associated with active chromatin. Proc Natl Acad Sci U S A 101: 1525-1530.
5. Mito Y, Henikoff JG, Henikoff S (2005) Genome-scale profiling of histone H3.3 replacement patterns. Nat Genet 37: 1090-1097.
6. Sullivan KF, Hechenberger M, Masri K (1994) Human CENP-A contains a histone H3 related histone fold domain that is required for targeting to the centromere. J Cell Biol 127: 581-592.
7. Henikoff S, Dalal Y (2005) Centromeric chromatin: What makes it unique? Curr Opin Genet Dev 15: 177-184.
8. Blower MD, Karpen GH (2001) The role of Drosophila CID in kinetochore formation, cell-cycle progression, and heterochromatin interactions. Nat Cell Biol 3: 730-739.
9. Buchwitz BJ, Ahmad K, Moore LL, Roth MB, Henikoff S (1999) A histone H3-like protein in C. elegans. Nature 401: 547-548.
10. Collins KA, Castillo AR, Tatsutani SY, Biggins S (2005) De novo kinetochore assembly requires the centromeric histone H3 variant. Mol Biol Cell 16: 5649-5660.
11. Takahashi K, Chen ES, Yanagida M (2000) Requirement of Mis6 centromere connector for localizing a CENP-A-like protein in fission yeast. Science 288: 2215-2219.
12. Howman EV, Fowler KJ, Newson AJ, Redward S, MacDonald AC, et al. (2000) Early disruption of centromeric chromatin organization in centromere protein A (CENP-A) null mice. Proc Natl Acad Sci U S A 97: 1148-1153.
13. Karpen GH, Allshire RC (1997) The case for epigenetic effects on centromere identity and function. Trends Genet 13: 489-496.
14. Warburton PE, Cooke CA, Bourassa S, Vafa O, Sullivan BA, et al. (1997) Immunolocalization of CENP-A suggests a distinct nucleosome structure at the inner kinetochore plate of active centromeres. Curr Biol 7: 901-904.
15. du Sart D, Cancilla MR, Earle E, Mao JI, Saffery R, et al. (1997) A functional neocentromere formed through activation of a latent human centromere and consisting of non-alpha-satellite DNA. Nat Genet 16: 144-153.
16. Lam AL, Boivin CD, Bonney CF, Rudd MK, Sullivan BA (2006) Human centromeric chromatin is a dynamic chromosomal domain that can spread over noncentromeric DNA. Proc Natl Acad Sci U S A 103: 4186-4191.
17. Saffery R, Irvine DV, Griffiths B, Kalitsis P, Wordeman L, et al. (2000) Human centromeres and neocentromeres show identical distribution patterns of >20 functionally important kinetochore-associated proteins. Hum Mol Genet 9: 175-185.
18. Satinover DL, Vance GH, Van Dyke DL, Schwartz S (2001) Cytogenetic analysis and construction of a BAC contig across a common neocentromeric region from 9p. Chromosoma 110: 275-283.
19. Alonso A, Mahmood R, Li S, Cheung F, Yoda K, et al. (2003) Genomic microarray analysis reveals distinct locations for the CENP-A binding domains in three human chromosome 13q32 neocentromeres. Hum Mol Genet 12: 2711-2721.
20. Williams BC, Murphy TD, Goldberg ML, Karpen GH (1998) Neocentromere activity of structurally acentric mini-chromosomes in Drosophila. Nat Genet 18: 30-37.
21. Maggert KA, Karpen GH (2001) The activation of a neocentromere in Drosophila requires proximity to an endogenous centromere. Genetics 158: 1615-1628.
22. Heun P, Erhardt S, Blower MD, Weiss S, Skora AD, et al. (2006) Mislocalization of the Drosophila centromere-specific histone CID promotes formation of functional ectopic kinetochores. Dev Cell 10: 303-315.
23. Takahashi K, Murakami S, Chikashige Y, Funabiki H, Niwa O, et al. (1992) A low copy number central sequence with strict symmetry and unusual chromatin structure in fission yeast centromere. Mol Biol Cell 3: 819-835.
24. Steiner NC, Clarke L (1994) A novel epigenetic effect can alter centromere function in .ssion yeast. Cell 79: 865-874.
25. Steiner NC, Hahnenberger KM, Clarke L (1993) Centromeres of the fission yeast Schizosaccharomyces pombe are highly variable genetic loci. Mol Cell Biol 13: 4578-4587.
26. Verdel A, Moazed D (2005) RNAi-directed assembly of heterochromatin in fission yeast. FEBS Lett 579: 5872-5878.
27. Polizzi C, Clarke L (1991) The chromatin structure of centromeres from fission yeast: Differentiation of the central core that correlates with function. J Cell Biol 112: 191-201.
28. Cam HP, Sugiyama T, Chen ES, Chen X, FitzGerald PC, et al. (2005) Comprehensive analysis of heterochromatin- and RNAi-mediated epigenetic control of the fission yeast genome. Nat Genet 37: 809-819.
29. Hayashi T, Fujita Y, Iwasaki O, Adachi Y, Takahashi K, et al. (2004) Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres. Cell 118: 715-729.
30. Goshima G, Saitoh S, Yanagida M (1999) Proper metaphase spindle length is determined by centromere proteins Mis12 and Mis6 required for faithful chromosome segregation. Genes Dev 13: 1664-1677.
31. Jin QW, Pidoux AL, Decker C, Allshire RC, Fleig U (2002) The mal2p protein is an essential component of the fission yeast centromere. Mol Cell Biol 22: 7168-7183.
32. Kerres A, Jakopec V, Beuter C, Karig I, Pohlmann J, et al. (2006) Fta2, an essential fission yeast kinetochore component, interacts closely with the conserved Mal2 protein. Mol Biol Cell 17: 4167-4178.
33. Liu X, McLeod I, Anderson S, Yates JR III, He X (2005) Molecular analysis of kinetochore architecture in fission yeast. EMBO J 24: 2919-2930.
34. Partridge JF, Scott KS, Bannister AJ, Kouzarides T, Allshire RC (2002) cisacting DNA from fission yeast centromeres mediates histone H3 methylation and recruitment of silencing factors and cohesin to an ectopic site. Curr Biol 12: 1652-1660.
35. Pidoux AL, Richardson W, Allshire RC (2003) Sim4: A novel fission yeast kinetochore protein required for centromeric silencing and chromosome segregation. J Cell Biol 161: 295-307.
36. Partridge JF, Borgstrom B, Allshire RC (2000) Distinct protein interaction domains and protein spreading in a complex centromere. Genes Dev 14: 783-791.
37. Scott KC, Merrett SL, Willard HF (2006) A heterochromatin barrier partitions the fission yeast centromere into discrete chromatin domains. Curr Biol 16: 119-129.
38. Allshire RC, Nimmo ER, Ekwall K, Javerzat JP, Cranston G (1995) Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation. Genes Dev 9: 218-233.
39. Allshire RC, Javerzat JP, Redhead NJ, Cranston G (1994) Position effect variegation at fission yeast centromeres. Cell 76: 157-169.
40. Baum M, Ngan VK, Clarke L (1994) The centromeric K-type repeat and the central core are together sufficient to establish a functional Schizosaccharomyces pombe centromere. Mol Biol Cell 5: 747-761.
41. Takahashi K, Takayama Y, Masuda F, Kobayashi Y, Saitoh S (2005) Two distinct pathways responsible for the loading of CENP-A to centromeres in the fission yeast cell cycle. Philos Trans R Soc Lond B Biol Sci 360: 595-606
42. Chen ES, Saitoh S, Yanagida M, Takahashi K (2003) A cell cycle-regulated GATA factor promotes centromeric localization of CENP-A in fission yeast. Mol Cell 11: 175-187.
43. Blower MD, Sullivan BA, Karpen GH (2002) Conserved organization of centromeric chromatin in flies and humans. Dev Cell 2: 319-330.
44. Collins KA, Furuyama S, Biggins S (2004) Proteolysis contributes to the exclusive centromere localization of the yeast Cse4/CENP-A histone H3 variant. Curr Biol 14: 1968-1972.
45. Matsumoto S, Yanagida M, Nurse P (1987) Histone transcription in cell cycle mutants of fission yeast. EMBO J 6: 1093-1097.
46. Matsumoto S, Yanagida M (1985) Histone gene organization of fission yeast: A common upstream sequence. EMBO J 4: 3531-3538.
47. Mellone BG, Ball L, Suka N, Grunstein MR, Partridge JF, et al. (2003) Centromere silencing and function in fission yeast is governed by the amino terminus of histone H3. Curr Biol 13: 1748-1757.
48. Kim SM, Dubey DD, Huberman JA (2003) Early-replicating heterochromatin. Genes Dev 17: 330-335.
49. Kim SM, Huberman JA (2001) Regulation of replication timing in fission yeast. EMBO J 20: 6115-6126.
50. Tomonaga T, Matsushita K, Yamaguchi S, Oohashi T, Shimada H, et al. (2003) Overexpression and mistargeting of centromere protein-A in human primary colorectal cancer. Cancer Res 63: 3511-3516.
51. Meeks-Wagner D, Hartwell LH (1986) Normal stoichiometry of histone dimer sets is necessary for high fidelity of mitotic chromosome transmission. Cell 44: 43-52.
52. Shelby RD, Monier K, Sullivan KF (2000) Chromatin assembly at kinetochores is uncoupled from DNA replication. J Cell Biol 151: 1113-1118.
53. Sullivan KF (2001) A solid foundation: Functional specialization of centromeric chromatin. Curr Opin Genet Dev 11: 182-188.
54. Moreno S, Klar A, Nurse P (1991) Molecular genetic-analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol 194: 795-823.
55. Bahler J, Wu JQ, Longtine MS, Shah NG, McKenzie A III, et al. (1998) Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe. Yeast 14: 943-951.
56. Ekwall K, Olsson T, Turner BM, Cranston G, Allshire RC (1997) Transient inhibition of histone deacetylation alters the structural and functional imprint at fission yeast centromeres. Cell 91: 1021-1032.
57. Pidoux A, Mellone B, Allshire R (2004) Analysis of chromatin in fission yeast. Methods 33: 252-259.
58. Kniola B, O'Toole E, McIntosh JR, Mellone B, Allshire R, et al. (2001) The domain structure of centromeres is conserved from fission yeast to humans. Mol Biol Cell 12: 2767-2775.
59. Pidoux AL, Uzawa S, Perry PE, Cande WZ, Allshire RC (2000) Live analysis of lagging chromosomes during anaphase and their effect on spindle elongation rate in fission yeast. J Cell Sci 113 (Pt 23): 4177-4191.