Reaction of β-lactam carbenes with alkyl isonitriles for a ready approach to 4-cyano and 4-carbamoyl substituted β-lactams

Tetrahedron

Volumn 63, Issue 38, 2007, Pages 9359-9364

  Cheng, Lan Qing ^a   Cheng, Ying ^a  

^a BEIJING NORMAL UNIVERSITY   (China)

Author keywords

Lactam carbene; 4 Carbamoyl lactam; 4 Cyano lactam; Ketenimine

Indexed keywords

1 (4 BROMOPHENYL) 4 CYANO 3,3 DIMETHYL 4 (1 PHENYLETHYL) BETA LACTAM; 1 (4 BROMOPHENYL) 4 CYANO 3,3 DIMETHYL 4 (4 FLUOROBENZYL) BETA LACTAM; 1 (4 BROMOPHENYL) 4 CYANO 3,3 DIMETHYL 4 (4 METHOXYBENZYL) BETA LACTAM; 1 (4 BROMOPHENYL) 4 CYCLOHEXYLCARBAMOYL 3,3 DIPHENYL BETA LACTAM; 1 (4 BROMOPHENYL)4 CYANO 3,3 DIMETHYL 4 (1 PHENYLETHYL) BETA LACTAM; 1 (4 CHLOROPHENYL) 3,3 DIPHENYL 4 (N HEXYLCARBAMOYL) BETA LACTAM; 3,3 DIMETHYL 4 (N HEXYLCARBAMOYL) 1 (4 METHOXYPHENYL) BETA LACTAM; 4 (N HEXYLCARBAMOYL) 3,3 DIPHENYL 1 (4 METHOXYPHENYL) BETA LACTAM; 4 (TERT BUTYLCARBAMOYL) 3,3 DIMETHYL 1 (4 METHOXYPHENYL) BETA LACTAM; 4 BENZYL 4 CYANO 3,3 DIMETHYL 1 (4 BROMOPHENYL) BETA LACTAM; 4 BENZYL 4 CYANO 3,3 DIMETHYL 1 (4 METHOXYPHENYL) BETA LACTAM; 4 BENZYL 4 CYANO 3,3 DIMETHYL 1 (4 METHYLPHENYL) BETA LACTAM; 4 BENZYL 4 CYANO 3,3 DIMETHYL 1 PHENYL BETA LACTAM; 4 CYANO 3,3 DIPHENYL 1 (4 BROMOPHENYL) 4 (4 METHOXYBENZYL) BETA LACTAM; 4 CYANO 3,3 DIPHENYL 1 (4 METHYLPHENYL) BETA LACTAM; 4 CYCLOHEXYLCARBAMOYL 3,3 DIPHENYL 1 (4 METHYLPHENYL) BETA LACTAM; ALKYL GROUP; BETA LACTAM; BETA LACTAM ANTIBIOTIC; CARBENE; CARBON; FUNCTIONAL GROUP; IMINE; ISONITRILE DERIVATIVE; KETENIMINE; NITROGEN; TRICHLOROETHYLENE; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; COMPARATIVE STUDY; DERIVATIZATION; DRUG ISOLATION; DRUG POTENCY; DRUG SYNTHESIS; HYDROLYSIS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; SUBSTITUTION REACTION;

EID: 34547579874     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2007.06.111     Document Type: Article

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