New analogues of the potent cytotoxic saponin OSW-1

Journal of Medicinal Chemistry

Volumn 50, Issue 15, 2007, Pages 3667-3673

  Wojtkielewicz, Agnieszka ^a   Długosz, Maciej ^b   Maj, Jadwiga ^a   Morzycki, Jacek W ^a   Nowakowski, Michał ^b   Renkiewicz, Joanna ^a   Strnad, Miroslav ^c   Swaczynová, Jana ^c   Wilczewska, Agnieszka Z ^a   Wójcik, Jacek ^b  

^a UNIVERSITY OF BIALYSTOK   (Poland)

^b INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^c PALACKÝ UNIVERSITY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

3BETA,16BETA,17ALPHA TRIHYDROXYCHOLEST 5 EN 22 ONE 16 O [O [2 O (4 MTEHOXYBENZOYL) BETA DEXTRO XYLOPYRANOSYL](1-3) 2 O ACETYL ALPHA ARABINOPYRANOSIDE; OSW 1; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL STRAIN 3T3; CHIRALITY; CONTROLLED STUDY; DRUG CONFORMATION; DRUG CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; ISOMER; MELANOMA CELL; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHOLESTENONES; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; SAPONINS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34547571520     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0613572     Document Type: Article

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