2D NMR and conformational analysis of a prototype anti-tumour steroidal ester

Journal of Pharmaceutical and Biomedical Analysis

Volumn 38, Issue 3, 2005, Pages 428-434

  Kapou, Agnes ^a,b   Fousteris, Manolis A ^a   Nikolaropoulos, Sotiris S ^a   Zervou, Maria ^b   Grdadolnik, Simona G ^c   Zoumpoulakis, Panagiotis ^b   Kyrikou, Ioanna ^b   Mavromoustakos, Thomas ^b  

^a UNIVERSITY OF PATRAS   (Greece)

^b INSTITUTE OF BIOLOGY   (Greece)

^c NATIONAL INSTITUTE OF CHEMISTRY   (Slovenia)

Author keywords

2D NOESY NMR; Anti tumour steroidal esters; Chlorambucil; Conformational analysis; Molecular modeling; Nitrogen mustards

Indexed keywords

3 BETA HYDROXY 17ALPHA AZA DEXTRO HOMO 5 ANDROSTEN 7,17 DIONE 4 N,N BIS(2 CHLOROETHYL)AMINOPHENYLACETATE; PHENYLACETIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CORRELATION ANALYSIS; DRUG MECHANISM; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; VALIDATION PROCESS;

ANTINEOPLASTIC AGENTS; ESTERS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; STEROIDS; TECHNOLOGY, PHARMACEUTICAL;

EID: 19544394290     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2005.01.012     Document Type: Article

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