Integration of the metabolic and cardiovascular effects of exercise

Essays in Biochemistry

Volumn 42, Issue , 2006, Pages 193-210

  Wagenmakers, Anton J M ^a,b   Van Riel, Natal A W ^b   Frenneaux, Michael P ^a   Stewart, Paul M ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRIC OXIDE; SUPEROXIDE;

ATHEROSCLEROSIS; BIOLOGICAL MODEL; CARDIOVASCULAR FUNCTION; EXERCISE; HUMAN; INFLAMMATION; INSULIN RESISTANCE; LIFESTYLE; METABOLIC SYNDROME X; METABOLISM; MICROCIRCULATION; OBESITY; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW; SKELETAL MUSCLE; SYSTEMS BIOLOGY; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; VASCULARIZATION;

ATHEROSCLEROSIS; CARDIOVASCULAR PHYSIOLOGY; ENDOTHELIUM, VASCULAR; EXERCISE; HUMANS; INFLAMMATION; INSULIN RESISTANCE; LIFE STYLE; METABOLIC SYNDROME X; MICROCIRCULATION; MODELS, CARDIOVASCULAR; MUSCLE, SKELETAL; MUSCLE, SMOOTH, VASCULAR; NF-KAPPA B; NITRIC OXIDE; OBESITY; SUPEROXIDES; SYSTEMS BIOLOGY;

EID: 34547564222     PISSN: 00711365     EISSN: None     Source Type: Journal    
DOI: 10.1042/bse0420193     Document Type: Article

References (39)

1. Chakravarthy, M.V. & Booth, F.W. (2004) Eating, exercise, and 'thrifty' genotypes: connecting the dots toward an evolutionary understanding of modern chronic diseases. J. Appl. Physiol. 96, 3-10
2. Frayn, K.N. (2002) Adipose tissue as a buffer for daily lipid flux. Diabetologia 45, 1201-1210
3. Anderson, P. & Saltin, B. (1985) Maximal perfusion of skeletal muscle in man. J. Physiol. 366, 233-249
4. Landmesser, U., Hornig, B. & Drexler, H. (2004) Endothelial function: a critical determinant in atherosclerosis? Circulation 109, 27-33
5. Brown, M.D., Davies, M.K. & Hudlicka, O. (2005) Angiogenesis in ischaemic and hypertrophic hearts induced by long-term bradycardia. Angiogenesis 8, 253-262
6. Hudlicka, O., Brown, M.D., May, S., Zakrzewicz, A. & Pries, A.R. (2006) Changes in capillary shear stress in skeletal muscles exposed to long-term activity: role of nitric oxide. Microcirculation 13, 249-259
7. rd July 2006.
8. Renkin, E.M. & Crone, C. (1996) Microcirculation and capillary exchange. In: Comprehensive Human Physiology, (Greger, R. & Windhorst, U., eds), pp 1965-1979, Berlin-Heidelberg Springer Verlag.
9. Gudbjörnsdóttir, S., Sjöstrand, M., Strindberg, L., Wahren, J. & Lönnroth, P. (2003) Direct measurements of the permeability surface area for insulin and glucose in human skeletal muscle. J. Clin. Endocrinol. Metab. 88, 4559-4564
10. Gudbjörnsdóttir, S., Sjöstrand, M., Strindberg, L & Lönnroth, P. (2005) Decreased muscle capillary permeability surface area in type 2 diabetic subjects. J. Clin. Endocrinol. Metab. 90, 1078-1082
11. Petersen, K.F., Dufour, S. & Shulman, G.I. (2005) Decreased insulin-stimulated rates of mitochondrial ATP synthesis and phosphate transport in skeletal muscle of insulin-resistant offspring of type 2 diabetic patients. PLoS Med 2, e233
12. Wagenmakers, A.J.M. (2005) Insulin resistance in the offspring of parents with type 2 diabetes. PLoS Med 2, e289
13. Itani, S.I., Zhou, Q., Pories, W.J., MacDonald, K.G. & Dohm, G.L (2000) Involvement of protein kinase C in human skeletal muscle insulin resistance and obesity. Diabetes 49, 1353-1358
14. Itani, S.I., Pories, W.J., Macdonald, K.G. & Dohm, G.L. (2001) Increased protein kinase C-θ in skeletal muscle of diabetic patients. Metabolism 50, 553-557
15. Itani, S.I., Ruderman, N.B., Schmieder, F. & Boden G. (2002) Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C and IκBα Diabetes 51, 2005-2011
16. Naruse, K., Rask-Madsen, C., Takahara, N., Ha, S.-W., Suzuma, K., Way, K.J., Jacobs, J.R.C., Clermont, A.C., Ueki, K., Ohshiro, Y. et al. (2006) Activation of vascular protein kinase C-β inhibits Akt-dependent endothelial nitric oxide synthase function in obesity-associated insulin resistance. Diabetes 55, 691-698
17. Yuan M., Konstantopoulos N., Lee J., Hansen L., Li Z.-W., Karin M. & Shoelson S.E. (2001) Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of IKKβ. Science 293, 1673-1677
18. Kim, F., Tysseling, K.A., Rice, J., Pham, M., Haji, L., Gallis, B.M., Baas, A.S., Paramsothy, P., Giachelli, C.M., Corson, M.A. & Raines, E.W. (2005) Free fatty acid impairment of nitric oxide production in endothelial cells is mediated by IKKβ. Arterioscler. Thromb. Vas. Biol. 25, 989-994
19. Kim, F., Tysseling, K.A., Rice, J., Gallis, B., Haji, L., Giachelli, C.M., Raines, E.W., Corson, M.A. & Schwartz, M.W. (2005) Activation of IKKβ by glucose is necessary and sufficient to impair insulin signaling and nitric oxide production in endothelial cells. J. Mol. Cell. Cardiol. 39, 327-334
20. Jones, W.K., Brown, M., Wilhide, M., He, S. & Ren, X. (2005) NF-κB in cardiovascular disease: diverse and specific effects of a 'general' transcription factor. Cardiovasc Toxicol. 5, 183-202
21. Shen, H.M. & Pervaiz, S. (2006) TNF receptor superfamily-induced cell death: redox dependent execution. FASEBJ. 20, 1589-1598
22. Brandes, R.P. & Kreuzer, J. (2005) Vascular NADPH oxidases: molecular mechanisms of activation. Cardiovasc Res. 65, 16-27
23. 2+/calmodulin- dependent and tetrahydrobiopterin regulatory process. J. Biol. Chem. 273, 25804-25808
24. Landmesser, U., Dikalov, S., Price, S.R., McCann, L., Fukai, T., Holland, S.M., Mitch, W.E. & Harrison, D.G. (2003) Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. J. Clin. Invest. 111, 1201-1209
25. Bevers, L.M., Braam, B., Post, J.A., van Zonneveld, A.J., Rabelink, T.J., Koomans, H.A., Verhaar, M.C., & Joles, J.A. (2006) Tetrahydrobiopterin, but not L-arginine, decreases NO synthase uncoupling in cells expressing high levels of endothelial NO synthase. Hypertension 47, 87-94
26. Nyström, T., Nygren, A. & Sjöholm, Å. (2004) Tetrahydrobiopterin increases insulin sensitivity in patients with type 2 diabetes and coronary heart disease. Am. J. Physiol. 287, E919-E925
27. Seynhave, A.L., Vermeulen, C.E., Eggermont, A.M. & Ten Hagen, T.L (2006) Cytokines and vascular permeability: an in vitro study on human endothelial cells in relation to tumor necrosis factor-α-primed peripheral blood mononuclear cells. Cell. Biochem. Biophys. 44, 157-169
28. Hoffmann, A. & Baltimore, D. (2006) Circuitry of nuclear factor κB signaling. Immunol. Rev. 210, 171-186
29. Campbell, K., J. & Perkins, N.D. (2006) Regulation of NF-κB function. Biochem. Soc Symp. 73, 165-180
30. Li, Y., Ha, T., Gao, X., Kelley, J., Williams, D.L., Browder, I.W., Kao, R.L. & Li, C. (2004) NF-κB activation is required for the development of cardiac hypertrophy in vivo. Am. J. Physiol. 287, H1712-H1720
31. Smith, R.S., Agata, J., Xia, C.F., Chao, L. & Chao, J. (2005) Human endothelial nitric oxide synthase gene delivery protects against cardiac remodeling and reduces oxidative stress after myocardial infarction. Life Sci. 76, 2457-2471
32. Jeffcoate, W.J., Game, F. & Cavanagh, P.R. (2005) The role of proinflammatory cytokines in the cause of neuropathic osteoarthropathy (acute Charcot foot) in diabetes. Lancet 366, 2058-2061
33. Pizzi, M. & Spano P. (2006) Distinct roles of diverse nuclear factor-kappaB complexes in neuropathological mechanisms. Eur. J. Pharmacol. 545, 22-28
34. Harada, C., Okumura, A., Namekata, K., Nakamura, K., Mitamura, Y., Ohguro, H., & Harada, T. (2006). Role of monocyte chemotactic protein-1 and nuclear factor-κB in the pathogenesis of proliferative diabetic retinopathy. Diabetes Res. Clin. Pract., doi: 10.1016/J.diabres. 2006.04.017
35. Zoja, C., Abbate, M. & Remuzzi, G. (2006) Progression of chronic kidney disease: insights from animal models. Curr. Opin. Neprol. Hypertens. 15, 250-257
36. Kitano H., Oda K., Kimura T. et al. (2004) Metabolic syndrome and robustness tradeoffs. Diabetes 53, S6-S15
37. Butcher E.C., Berg E. L. & Kunkel E. J. (2004) Systems biology in drug discovery. Nat. Biotech. 22, 1253-1259
38. Scheuermann-Freestone, M., Madsen, P.L., Manners D., Blamire, A.M., Buckingham, R.E., Styles, P., Radda, G.K., Neubauer, S. & Clarke, K. (2003) Abnormal cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes. Circulation 107, 3040-3046
39. Lam, C.-F., Peterson, T.E., Richardson, D.M., Croatt, A.J., d'Uscio, L.V., Nath, K.A. & Katusic, Z.S. (2006) Increased blood flow causes coordinated upregulation of arterial eNOS and biosynthesis of tetrahydriobiopterin. Am. J. Physiol. 290, H786-H793