Structural and functional analysis of the ligand specificity of the HtrA2/Omi PDZ domain

Protein Science

Volumn 16, Issue 8, 2007, Pages 1738-1750

  Zhang, Yingnan ^a   Appleton, Brent A ^a   Wu, Ping ^a   Wiesmann, Christian ^a   Sidhu, Sachdev S ^a  

^a GENENTECH INC   (United States)

Author keywords

Apoptosis; Mitochondria; PDZ domain; Peptide binding module; Serine protease

Indexed keywords

HYBRID PROTEIN; LIGAND; SERINE PROTEINASE OMI;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIGAND BINDING; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY;

ALANINE; AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; LIGANDS; MITOCHONDRIAL PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; SERINE ENDOPEPTIDASES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 34547559252     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1110/ps.072833207     Document Type: Article

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