Engineering high-speed allosteric hammerhead ribozymes

Biological Chemistry

Volumn 388, Issue 8, 2007, Pages 779-786

  Link, Kristian H ^a   Guo, Lixia ^a   Ames, Tyler D ^a   Yen, Laising ^b   Mulligan, Richard C ^b   Breaker, Ronald R ^a  

^a YALE UNIVERSITY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Aptamer; Riboswitch; RNA folding; RNA switch; Self cleavage; Theophylline

Indexed keywords

ENZYME VARIANT; HAMMERHEAD RIBOZYME; MAGNESIUM; RNA; THEOPHYLLINE;

ALLOSTERISM; ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME KINETICS; GENE ACTIVITY; GENE CONTROL; GENE EXPRESSION REGULATION; GENE ISOLATION; GENE SEQUENCE; GENETIC ENGINEERING; HUMAN; HUMAN CELL; IN VITRO SELECTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; REPORTER GENE;

ALLOSTERIC REGULATION; ALLOSTERIC SITE; ANIMALS; BASE SEQUENCE; CAFFEINE; CELL LINE; CLONE CELLS; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; REGULATORY SEQUENCES, RIBONUCLEIC ACID; RNA, CATALYTIC; SCHISTOSOMA MANSONI; SELEX APTAMER TECHNIQUE; SEQUENCE ANALYSIS, RNA; THEOPHYLLINE;

EID: 34547519117     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2007.105     Document Type: Article

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