Computational design and experimental validation of oligonucleotide-sensing allosteric ribozymes

Nature Biotechnology

Volumn 23, Issue 11, 2005, Pages 1424-1433

  Penchovsky, Robert ^a   Breaker, Ronald R ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMEDICAL ENGINEERING; CATALYSIS; FUNCTIONS;

LIGAND BINDING; RNA ENGINEERING;

RNA;

RIBOZYME; RNA; SYNTHETIC DNA;

ALLOSTERISM; ARTICLE; BINDING SITE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME ENGINEERING; ENZYME SPECIFICITY; OLIGONUCLEOTIDE PROBE; PRIORITY JOURNAL; VALIDATION PROCESS;

ALLOSTERIC SITE; ANIMALS; BASE SEQUENCE; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; GENETIC ENGINEERING; LIGANDS; MATHEMATICAL COMPUTING; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; PROGRAMMING LANGUAGES; RNA; RNA, CATALYTIC; SCHISTOSOMA; SIGNAL TRANSDUCTION; SOFTWARE;

EID: 27944493648     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt1155     Document Type: Article

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