Synthesis, structure-activity relationship, and evaluation of SR141716 analogues: Development of central cannabinoid receptor ligands with lower lipophilicity

Journal of Medicinal Chemistry

Volumn 46, Issue 4, 2003, Pages 642-645

  Katoch Rouse, Reeti ^a   Pavlova, Olga A ^a   Caulder, Tara ^a   Hoffman, Alexander F ^a   Mukhin, Alexey G ^a   Horti, Andrew G ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANNABINOID RECEPTOR; RADIOLIGAND; RIMONABANT; TRACER;

ARTICLE; BINDING AFFINITY; BRAIN HOMOGENATE; DRUG SCREENING; DRUG SYNTHESIS; ELECTROPHYSIOLOGY; LIPOPHILICITY; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PROTEIN FUNCTION; RAT; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; TECHNIQUE;

ANIMALS; CANNABINOIDS; CEREBELLUM; LIGANDS; MEMBRANE POTENTIALS; MORPHOLINES; NAPHTHALENES; NUCLEUS ACCUMBENS; PIPERIDINES; PYRAZOLES; RADIOLIGAND ASSAY; RATS; RECEPTORS, CANNABINOID; RECEPTORS, DRUG; STRUCTURE-ACTIVITY RELATIONSHIP; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0037434591     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020157x     Document Type: Article

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