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Douthwhite et al. supposed the existence of these species as intermediates in the reaction of allylic alkylation using iminocarbene ligands (see ref 7a).
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34547423294
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This signal is visible only for the major exo isomer
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This signal is visible only for the major exo isomer.
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61
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a values for piperidine and benzylamine are 11.12 and 9.34, respectively (Albert, A.; Serjeant, E. P. In The Determination of Ionization Constant; Chapman and Hall: London, 1984; p 151.
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76
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34547461671
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For example [Pd-(η3-allyl)(NHR2) 2, are pratically inert toward nucleophilic attack see ref 30a
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+ are pratically inert toward nucleophilic attack (see ref 30a).
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0001448190
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34547470475
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The unreacted 1,3-diphenylallylethyl carbonate was still racemic
-
The unreacted 1,3-diphenylallylethyl carbonate was still racemic.
-
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81
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34547403084
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It seems improbable that the minor isomers may display such different rates for the nucleophilic attack to compensate for a possible preferential attack at one allylic terminus in the major isomer. Indeed, the case of a pyrazole-phosphine complex with an isomeric distribution very similar to 6f was reported, for which a preferential attack at the carbon trans to phosphorus led to high ee's see ref 11a
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It seems improbable that the minor isomers may display such different rates for the nucleophilic attack to compensate for a possible preferential attack at one allylic terminus in the major isomer. Indeed, the case of a pyrazole-phosphine complex with an isomeric distribution very similar to 6f was reported, for which a preferential attack at the carbon trans to phosphorus led to high ee's (see ref 11a).
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82
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Perry, M. C.; Cui, X.; Powell, M. T.; Hou, D.; Rebenspeis, J. H.; Burgess, K. J. Am. Chem. Soc. 2003, 125, 113.
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Perry, M.C.1
Cui, X.2
Powell, M.T.3
Hou, D.4
Rebenspeis, J.H.5
Burgess, K.6
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Goddard, R.; Krüger, C.; Mynott, R.; Neumann, M.; Wilke, G. J. Organomet. Chem. 1993, C20-C25, 454.
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J. Organomet. Chem
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Goddard, R.1
Krüger, C.2
Mynott, R.3
Neumann, M.4
Wilke, G.5
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