Simvastatin prevents oxygen and glucose deprivation/reoxygenation-induced death of cortical neurons by reducing the production and toxicity of 4-hydroxy-2E-nonenal

Journal of Neurochemistry

Volumn 97, Issue 1, 2006, Pages 140-150

  Lim, Ji Hyae ^a   Lee, Jae Chul ^a   Lee, Yong Hyun ^a   Choi, In Young ^a   Oh, Yu Kyoung ^b   Kim, Hee Sun ^a   Park, Jin Sun ^a   Kim, Won Ki ^a  

^a Ewha Womans University School of Medicine   (South Korea)

^b Korea University   (South Korea)

Author keywords

4 hydroxy 2E nonenal; Ischemia; Nuclear factor kappa B; Simvastatin

Indexed keywords

4 HYDROXYNONENAL; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; DIZOCILPINE; GLUCOSE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; OXYGEN; SIMVASTATIN;

ANIMAL CELL; ARTICLE; BRAIN CELL; CALCIUM TRANSPORT; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; DEGENERATIVE DISEASE; ENZYME ACTIVATION; ENZYME ACTIVITY; EXCITOTOXICITY; FETUS; GLIA CELL; LIPID PEROXIDATION; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REOXYGENATION; TOXICITY;

ALDEHYDES; ANIMALS; CELL DEATH; CELLS, CULTURED; CEREBRAL CORTEX; CYTOPROTECTION; ENZYME INHIBITORS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPOXIA-ISCHEMIA, BRAIN; LIPID PEROXIDATION; NERVE DEGENERATION; NEURONS; NEUROPROTECTIVE AGENTS; NEUROTOXINS; NF-KAPPA B; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; SIMVASTATIN;

ANIMALIA;

EID: 33644946838     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.03715.x     Document Type: Article

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