-
1
-
-
12944300987
-
Caspofungin inhibits Rhizopus oryzae 1,3-beta-D-glucan synthase, lowers burden in brain measured by quantitative PCR, and improves survival at a low but not a high dose during murine disseminated zygomycosis
-
IBRAHIM AS, BOWMAN JC, AVANESSIAN V et al.: Caspofungin inhibits Rhizopus oryzae 1,3-beta-D-glucan synthase, lowers burden in brain measured by quantitative PCR, and improves survival at a low but not a high dose during murine disseminated zygomycosis. Antimicrob. Agents Chemother. (2005) 49:721-727.
-
(2005)
Antimicrob. Agents Chemother
, vol.49
, pp. 721-727
-
-
IBRAHIM, A.S.1
BOWMAN, J.C.2
AVANESSIAN, V.3
-
2
-
-
12944268368
-
Combination therapy with amphotericin B lipid complex and caspofungin acetate of disseminated zygomycosis in diabetic ketoacidotic mice
-
SPELLBERG B, FU Y, EDWARDS JE Jr, IBRAHIM AS: Combination therapy with amphotericin B lipid complex and caspofungin acetate of disseminated zygomycosis in diabetic ketoacidotic mice. Antimicrob. Agents Chemother. (2005) 49:830-832.
-
(2005)
Antimicrob. Agents Chemother
, vol.49
, pp. 830-832
-
-
SPELLBERG, B.1
FU, Y.2
EDWARDS Jr, J.E.3
IBRAHIM, A.S.4
-
3
-
-
33947187696
-
Comparison of antifungal treatments for murine fusariosis
-
SPELLBERG B, SCHWARTZ J, FU Y et al.: Comparison of antifungal treatments for murine fusariosis. J. Antimicrob. Chemother. (2006) 58:973-979.
-
(2006)
J. Antimicrob. Chemother
, vol.58
, pp. 973-979
-
-
SPELLBERG, B.1
SCHWARTZ, J.2
FU, Y.3
-
4
-
-
0033680483
-
The effect of the echinocandin analogue caspofungin on cell wall glucan synthesis by Cryptococcus neoformans
-
FELDMESSER M, KRESS Y, MEDNICK A, CASADEVALL A: The effect of the echinocandin analogue caspofungin on cell wall glucan synthesis by Cryptococcus neoformans. J. Infect. Dis. (2000) 182:1791-1795.
-
(2000)
J. Infect. Dis
, vol.182
, pp. 1791-1795
-
-
FELDMESSER, M.1
KRESS, Y.2
MEDNICK, A.3
CASADEVALL, A.4
-
5
-
-
0032925368
-
A glucan synthase FKS1 homolog in Cryptococcus neoformans is single copy and encodes an essential function
-
THOMPSON JR, DOUGLAS CM, LI W et al.: A glucan synthase FKS1 homolog in Cryptococcus neoformans is single copy and encodes an essential function. J. Bacteriol. (1999) 181:444-453.
-
(1999)
J. Bacteriol
, vol.181
, pp. 444-453
-
-
THOMPSON, J.R.1
DOUGLAS, C.M.2
LI, W.3
-
6
-
-
21444455677
-
Cryptococcus neoformans resistance to echinocandins: (1,3)beta-glucan synthase activity is sensitive to echinocandins
-
MALIGIE MA, SELITRENNIKOFF CP: Cryptococcus neoformans resistance to echinocandins: (1,3)beta-glucan synthase activity is sensitive to echinocandins. Antimicrob. Agents Chemother. (2005) 49:2851-2856.
-
(2005)
Antimicrob. Agents Chemother
, vol.49
, pp. 2851-2856
-
-
MALIGIE, M.A.1
SELITRENNIKOFF, C.P.2
-
7
-
-
0346433839
-
The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signaling
-
REINOSO-MARTIN C, SCHULLER C, SCHUETZER-MUEHLBAUER M, KUCHLER K: The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signaling. Eukaryot. Cell (2003) 2:1200-1210.
-
(2003)
Eukaryot. Cell
, vol.2
, pp. 1200-1210
-
-
REINOSO-MARTIN, C.1
SCHULLER, C.2
SCHUETZER-MUEHLBAUER, M.3
KUCHLER, K.4
-
8
-
-
0029892037
-
Identification of yeast Rho1p GTPase as a regulatory subunit of 1,3-beta-glucan synthase
-
QADOTA H, PYTHON CP, INOUE SB et al.: Identification of yeast Rho1p GTPase as a regulatory subunit of 1,3-beta-glucan synthase. Science (1996) 272:279-281.
-
(1996)
Science
, vol.272
, pp. 279-281
-
-
QADOTA, H.1
PYTHON, C.P.2
INOUE, S.B.3
-
9
-
-
0030671386
-
Identification of the FKS1 gene of Candida albicans as the essential target of 1,3-beta-D-glucan synthase inhibitors
-
DOUGLAS CM, D'IPPOLITO JA, SHEI GJ et al.: Identification of the FKS1 gene of Candida albicans as the essential target of 1,3-beta-D-glucan synthase inhibitors. Antimicrob. Agents Chemother. (1997) 41:2471-2479.
-
(1997)
Antimicrob. Agents Chemother
, vol.41
, pp. 2471-2479
-
-
DOUGLAS, C.M.1
D'IPPOLITO, J.A.2
SHEI, G.J.3
-
10
-
-
23044471740
-
Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates
-
PARK S, KELLY R, KAHN JN et al.: Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates. Antimicrob. Agents Chemother. (2005) 49:3264-3273.
-
(2005)
Antimicrob. Agents Chemother
, vol.49
, pp. 3264-3273
-
-
PARK, S.1
KELLY, R.2
KAHN, J.N.3
-
11
-
-
33748695822
-
-
STEVENS DA, ICHINOMIYA M, KOSHI Y, HORIUCHI H: Escape of Candida from caspofungin inhibition at concentrations above the MIC (paradoxical effect) accomplished by increased cell wall chitin; evidence for beta-1,6-glucan synthesis inhibition by caspofungin. Antimicrob. Agents Chemother. (2006) 50:3160-3161.
-
STEVENS DA, ICHINOMIYA M, KOSHI Y, HORIUCHI H: Escape of Candida from caspofungin inhibition at concentrations above the MIC (paradoxical effect) accomplished by increased cell wall chitin; evidence for beta-1,6-glucan synthesis inhibition by caspofungin. Antimicrob. Agents Chemother. (2006) 50:3160-3161.
-
-
-
-
12
-
-
0028568052
-
The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1,3-beta-D-glucan synthase
-
DOUGLAS CM, FOOR F, MARRINAN JA et al.: The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1,3-beta-D-glucan synthase. Proc. Natl. Acad. Sci. USA (1994) 91:12907-12911.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12907-12911
-
-
DOUGLAS, C.M.1
FOOR, F.2
MARRINAN, J.A.3
-
13
-
-
4644370711
-
Caspofungin uptake is mediated by a high-affinity transporter in Candida albicans
-
PADERU P, PARK S, PERLIN DS: Caspofungin uptake is mediated by a high-affinity transporter in Candida albicans. Antimicrob. Agents Chemother. (2004) 48:3845-3849.
-
(2004)
Antimicrob. Agents Chemother
, vol.48
, pp. 3845-3849
-
-
PADERU, P.1
PARK, S.2
PERLIN, D.S.3
-
14
-
-
0035668391
-
Fungal beta(1,3)-D-glucan synthesis
-
DOUGLAS CM: Fungal beta(1,3)-D-glucan synthesis. Med. Mycol. (2001) 39(Suppl. 1):55-66.
-
(2001)
Med. Mycol
, vol.39
, Issue.SUPPL. 1
, pp. 55-66
-
-
DOUGLAS, C.M.1
-
15
-
-
0029128074
-
Differential expression and function of two homologous subunits of yeast 1,3-beta-D-glucan synthase
-
MAZUR P, MORIN N, BAGINSKY W et al.: Differential expression and function of two homologous subunits of yeast 1,3-beta-D-glucan synthase. Mol. Cell Biol. (1995) 15:5671-5681.
-
(1995)
Mol. Cell Biol
, vol.15
, pp. 5671-5681
-
-
MAZUR, P.1
MORIN, N.2
BAGINSKY, W.3
-
16
-
-
15844412765
-
In vitro activity of 1,3-beta-D-glucan synthase requires the GTP-binding protein Rho1
-
MAZUR P, BAGINSKY W: In vitro activity of 1,3-beta-D-glucan synthase requires the GTP-binding protein Rho1. J. Biol. Chem. (1996) 271:14604-14609.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 14604-14609
-
-
MAZUR, P.1
BAGINSKY, W.2
-
17
-
-
0030005715
-
Cell shape determination: A pivotal role for Rho
-
BUSSEY H: Cell shape determination: a pivotal role for Rho. Science (1996) 272:224-225.
-
(1996)
Science
, vol.272
, pp. 224-225
-
-
BUSSEY, H.1
-
18
-
-
0030785108
-
Cloning of the RHO1 gene from Candida albicans and its regulation of beta-1,3-glucan synthesis
-
KONDOH O, TACHIBANA Y, OHYA Y, ARISAWA M, WATANABE T: Cloning of the RHO1 gene from Candida albicans and its regulation of beta-1,3-glucan synthesis. J. Bacteriol. (1997) 179:7734-7741.
-
(1997)
J. Bacteriol
, vol.179
, pp. 7734-7741
-
-
KONDOH, O.1
TACHIBANA, Y.2
OHYA, Y.3
ARISAWA, M.4
WATANABE, T.5
-
19
-
-
0035088108
-
Glucan synthase complex of Aspergillus fumigatus
-
BEAUVAIS A, BRUNEAU JM, MOL PC, BUITRAGO MJ, LEGRAND R, LATGE JP: Glucan synthase complex of Aspergillus fumigatus. J. Bacteriol. (2001) 183:2273-2279.
-
(2001)
J. Bacteriol
, vol.183
, pp. 2273-2279
-
-
BEAUVAIS, A.1
BRUNEAU, J.M.2
MOL, P.C.3
BUITRAGO, M.J.4
LEGRAND, R.5
LATGE, J.P.6
-
20
-
-
1642420267
-
Caspofungin resistance in Candida albicans: Correlating clinical outcome with laboratory susceptibility testing of three isogenic isolates serially obtained from a patient with progressive Candida esophagitis
-
HERNANDEZ S, LOPEZ-RIBOT JL, NAJVAR LK, MCCARTHY DI, BOCANEGRA R, GRAYBILL JR: Caspofungin resistance in Candida albicans: correlating clinical outcome with laboratory susceptibility testing of three isogenic isolates serially obtained from a patient with progressive Candida esophagitis. Antimicrob. Agents Chemother. (2004) 48:1382-1383.
-
(2004)
Antimicrob. Agents Chemother
, vol.48
, pp. 1382-1383
-
-
HERNANDEZ, S.1
LOPEZ-RIBOT, J.L.2
NAJVAR, L.K.3
MCCARTHY, D.I.4
BOCANEGRA, R.5
GRAYBILL, J.R.6
-
21
-
-
33744504444
-
Assessing resistance to the echinocandin antifungal drug caspofungin in Candida albicans by profiling mutations in FKS1
-
BALASHOV SV, PARK S, PERLIN DS: Assessing resistance to the echinocandin antifungal drug caspofungin in Candida albicans by profiling mutations in FKS1. Antimicrob. Agents Chemother. (2006) 50:2058-2063.
-
(2006)
Antimicrob. Agents Chemother
, vol.50
, pp. 2058-2063
-
-
BALASHOV, S.V.1
PARK, S.2
PERLIN, D.S.3
-
22
-
-
33746922380
-
Candida albicans and Candida glabrata clinical isolates exhibiting reduced echinocandin susceptibility
-
KATIYAR S, PFALLER M, EDLIND T: Candida albicans and Candida glabrata clinical isolates exhibiting reduced echinocandin susceptibility. Antimicrob. Agents Chemother. (2006) 50:2892-2894.
-
(2006)
Antimicrob. Agents Chemother
, vol.50
, pp. 2892-2894
-
-
KATIYAR, S.1
PFALLER, M.2
EDLIND, T.3
-
23
-
-
33645111403
-
Progressive loss of echinocandin activity following prolonged use for treatment of Candida albicans oesophagitis
-
LAVERDIERE M, LALONDE RG, BARIL JG, SHEPPARD DC, PARK S, PERLIN DS: Progressive loss of echinocandin activity following prolonged use for treatment of Candida albicans oesophagitis. J. Antimicrob. Chemother. (2006) 57:705-708.
-
(2006)
J. Antimicrob. Chemother
, vol.57
, pp. 705-708
-
-
LAVERDIERE, M.1
LALONDE, R.G.2
BARIL, J.G.3
SHEPPARD, D.C.4
PARK, S.5
PERLIN, D.S.6
-
24
-
-
33744494301
-
Progressive esophagitis caused by Candida albicans with reduced susceptibility to caspofungin
-
MILLER CD, LOMAESTRO BW, PARK S, PERLIN DS: Progressive esophagitis caused by Candida albicans with reduced susceptibility to caspofungin. Pharmacotherapy (2006) 26:877-880.
-
(2006)
Pharmacotherapy
, vol.26
, pp. 877-880
-
-
MILLER, C.D.1
LOMAESTRO, B.W.2
PARK, S.3
PERLIN, D.S.4
-
25
-
-
22844431862
-
Characterization of Aspergillus fumigatus mutants with reduced susceptibility to caspofungin
-
GARDINER RE, SOUTEROPOULOS P, PARK S, PERLIN DS: Characterization of Aspergillus fumigatus mutants with reduced susceptibility to caspofungin. Med. Mycol. (2005) 43(Suppl. 1):S299-S305.
-
(2005)
Med. Mycol
, vol.43
, Issue.SUPPL. 1
-
-
GARDINER, R.E.1
SOUTEROPOULOS, P.2
PARK, S.3
PERLIN, D.S.4
-
26
-
-
17044455920
-
In vitro preclinical evaluation studies with the echinocandin antifungal MK-0991 (L-743,872)
-
BARTIZAL K, GILL CJ, ABRUZZO GK et al.: In vitro preclinical evaluation studies with the echinocandin antifungal MK-0991 (L-743,872). Antimicrob. Agents Chemother. (1997) 41:2326-2332.
-
(1997)
Antimicrob. Agents Chemother
, vol.41
, pp. 2326-2332
-
-
BARTIZAL, K.1
GILL, C.J.2
ABRUZZO, G.K.3
-
27
-
-
0036170209
-
Single- and multiple-dose pharmacokinetics of caspofungin in healthy men
-
STONE JA, HOLLAND SD, WICKERSHAM PJ et al.: Single- and multiple-dose pharmacokinetics of caspofungin in healthy men. Antimicrob. Agents Chemother. (2002) 46:739-745.
-
(2002)
Antimicrob. Agents Chemother
, vol.46
, pp. 739-745
-
-
STONE, J.A.1
HOLLAND, S.D.2
WICKERSHAM, P.J.3
-
28
-
-
0035144963
-
Compartmental pharmacokinetics of the antifungal echinocandin caspofungin (MK-0991) in rabbits
-
GROLL AH, GULLICK BM, PETRAITIENE R et al.: Compartmental pharmacokinetics of the antifungal echinocandin caspofungin (MK-0991) in rabbits. Antimicrob. Agents Chemother. (2001) 45:596-600.
-
(2001)
Antimicrob. Agents Chemother
, vol.45
, pp. 596-600
-
-
GROLL, A.H.1
GULLICK, B.M.2
PETRAITIENE, R.3
-
29
-
-
28844486224
-
Pharmacodynamics of caspofungin in a murine model of systemic candidiasis: Importance of persistence of caspofungin in tissues to understanding drug activity
-
LOUIE A, DEZIEL M, LIU W, DRUSANO MF, GUMBO T, DRUSANO GL: Pharmacodynamics of caspofungin in a murine model of systemic candidiasis: importance of persistence of caspofungin in tissues to understanding drug activity. Antimicrob. Agents Chemother. (2005) 49:5058-5068.
-
(2005)
Antimicrob. Agents Chemother
, vol.49
, pp. 5058-5068
-
-
LOUIE, A.1
DEZIEL, M.2
LIU, W.3
DRUSANO, M.F.4
GUMBO, T.5
DRUSANO, G.L.6
-
30
-
-
0030711704
-
Preliminary animal pharmacokinetics of the parenteral antifungal agent MK-0991 (L-743,872)
-
HAJDU R, THOMPSON R, SUNDELOF JG et al.: Preliminary animal pharmacokinetics of the parenteral antifungal agent MK-0991 (L-743,872). Antimicrob. Agents Chemother. (1997) 41:2339-2344.
-
(1997)
Antimicrob. Agents Chemother
, vol.41
, pp. 2339-2344
-
-
HAJDU, R.1
THOMPSON, R.2
SUNDELOF, J.G.3
-
31
-
-
0034905598
-
Caspofungin: Pharmacology, safety and therapeutic potential in superficial and invasive fungal infections
-
GROLL AH, WALSH TJ: Caspofungin: pharmacology, safety and therapeutic potential in superficial and invasive fungal infections. Expert Opin. Investig. Drugs (2001) 10:1545-1558.
-
(2001)
Expert Opin. Investig. Drugs
, vol.10
, pp. 1545-1558
-
-
GROLL, A.H.1
WALSH, T.J.2
-
32
-
-
4944230721
-
Pharmacodynamics of caspofungin in a murine model of invasive pulmonary aspergillosis: Evidence of concentration-dependent activity
-
WIEDERHOLD NP, KONTOYIANNIS DP, CHI J, PRINCE RA, TAM VH, LEWIS RE: Pharmacodynamics of caspofungin in a murine model of invasive pulmonary aspergillosis: evidence of concentration-dependent activity. J. Infect. Dis. (2004) 190:1464-1471.
-
(2004)
J. Infect. Dis
, vol.190
, pp. 1464-1471
-
-
WIEDERHOLD, N.P.1
KONTOYIANNIS, D.P.2
CHI, J.3
PRINCE, R.A.4
TAM, V.H.5
LEWIS, R.E.6
-
33
-
-
0042349758
-
Effects of amphotericin B and caspofungin on histamine expression
-
CLEARY JD, SCHWARTZ M, ROGERS PD, DE MESTRAL J, CHAPMAN SW: Effects of amphotericin B and caspofungin on histamine expression. Pharmacotherapy (2003) 23:966-973.
-
(2003)
Pharmacotherapy
, vol.23
, pp. 966-973
-
-
CLEARY, J.D.1
SCHWARTZ, M.2
ROGERS, P.D.3
DE MESTRAL, J.4
CHAPMAN, S.W.5
-
34
-
-
10744227193
-
Disposition of caspofungin: Role of distribution in determining pharmacokinetics in plasma
-
STONE JA, XU X, WINCHELL GA et al.: Disposition of caspofungin: role of distribution in determining pharmacokinetics in plasma. Antimicrob. Agents Chemother. (2004) 48:815-823.
-
(2004)
Antimicrob. Agents Chemother
, vol.48
, pp. 815-823
-
-
STONE, J.A.1
XU, X.2
WINCHELL, G.A.3
-
35
-
-
1642543135
-
Disposition of caspofungin, a novel antifungal agent, in mice, rats, rabbits, and monkeys
-
SANDHU P, XU X, BONDISKEY PJ et al.: Disposition of caspofungin, a novel antifungal agent, in mice, rats, rabbits, and monkeys. Antimicrob. Agents Chemother. (2004) 48:1272-1280.
-
(2004)
Antimicrob. Agents Chemother
, vol.48
, pp. 1272-1280
-
-
SANDHU, P.1
XU, X.2
BONDISKEY, P.J.3
-
36
-
-
17844402485
-
Hepatic uptake of the novel antifungal agent caspofungin
-
SANDHU P, LEE W, XU X et al.: Hepatic uptake of the novel antifungal agent caspofungin. Drug Metab. Dispos. (2005) 33:676-682.
-
(2005)
Drug Metab. Dispos
, vol.33
, pp. 676-682
-
-
SANDHU, P.1
LEE, W.2
XU, X.3
-
37
-
-
0033787342
-
Metabolites of caspofungin acetate, a potent antifungal agent, in human plasma and urine
-
BALANI SK, XU X, ARISON BH et al.: Metabolites of caspofungin acetate, a potent antifungal agent, in human plasma and urine. Drug Metab. Dispos. (2000) 28:1274-1278.
-
(2000)
Drug Metab. Dispos
, vol.28
, pp. 1274-1278
-
-
BALANI, S.K.1
XU, X.2
ARISON, B.H.3
-
38
-
-
32644466027
-
Treatment with caspofungin in immunocompromised paediatric patients: A multicentre survey
-
GROLL AH, ATTARBASCHI A, SCHUSTER FR et al.: Treatment with caspofungin in immunocompromised paediatric patients: a multicentre survey. J. Antimicrob. Chemother. (2006) 57:527-535.
-
(2006)
J. Antimicrob. Chemother
, vol.57
, pp. 527-535
-
-
GROLL, A.H.1
ATTARBASCHI, A.2
SCHUSTER, F.R.3
-
39
-
-
27644585388
-
Pharmacokinetics, safety, and tolerability of caspofungin in children and adolescents
-
WALSH TJ, ADAMSON PC, SEIBEL NL et al.: Pharmacokinetics, safety, and tolerability of caspofungin in children and adolescents. Antimicrob. Agents Chemother. (2005) 49:4536-4545.
-
(2005)
Antimicrob. Agents Chemother
, vol.49
, pp. 4536-4545
-
-
WALSH, T.J.1
ADAMSON, P.C.2
SEIBEL, N.L.3
-
40
-
-
16644371770
-
Caspofungin therapy of neonates with invasive candidiasis
-
ODIO CM, ARAYA R, PINTO LE et al.: Caspofungin therapy of neonates with invasive candidiasis. Pediatr. Infect. Dis. J. (2004) 23:1093-1097.
-
(2004)
Pediatr. Infect. Dis. J
, vol.23
, pp. 1093-1097
-
-
ODIO, C.M.1
ARAYA, R.2
PINTO, L.E.3
-
41
-
-
7244258914
-
Potential for interactions between caspofungin and nelfinavir or rifampin
-
STONE JA, MIGOYA EM, HICKEY L et al.: Potential for interactions between caspofungin and nelfinavir or rifampin. Antimicrob. Agents Chemother. (2004) 48:4306-4314.
-
(2004)
Antimicrob. Agents Chemother
, vol.48
, pp. 4306-4314
-
-
STONE, J.A.1
MIGOYA, E.M.2
HICKEY, L.3
-
42
-
-
3843088493
-
Interlaboratory comparison of results of susceptibility testing with caspofungin against Candida and Aspergillus species
-
ODDS FC, MOTYL M, ANDRADE R et al.: Interlaboratory comparison of results of susceptibility testing with caspofungin against Candida and Aspergillus species. J. Clin. Microbiol. (2004) 42:3475-3482.
-
(2004)
J. Clin. Microbiol
, vol.42
, pp. 3475-3482
-
-
ODDS, F.C.1
MOTYL, M.2
ANDRADE, R.3
-
43
-
-
24144492350
-
Caspofungin susceptibility testing of isolates from patients with esophageal candidiasis or invasive candidiasis: Relationship of MIC to treatment outcome
-
KARTSONIS N, KILLAR J, MIXSON L et al.: Caspofungin susceptibility testing of isolates from patients with esophageal candidiasis or invasive candidiasis: relationship of MIC to treatment outcome. Antimicrob. Agents Chemother. (2005) 49:3616-3623.
-
(2005)
Antimicrob. Agents Chemother
, vol.49
, pp. 3616-3623
-
-
KARTSONIS, N.1
KILLAR, J.2
MIXSON, L.3
-
44
-
-
0032965923
-
In vitro pharmacodynamic properties of MK-0991 determined by time-kill methods
-
ERNST EJ, KLEPSER ME, ERNST ME, MESSER SA, PFALLER MA: In vitro pharmacodynamic properties of MK-0991 determined by time-kill methods. Diagn. Microbiol. Infect. Dis. (1999) 33:75-80.
-
(1999)
Diagn. Microbiol. Infect. Dis
, vol.33
, pp. 75-80
-
-
ERNST, E.J.1
KLEPSER, M.E.2
ERNST, M.E.3
MESSER, S.A.4
PFALLER, M.A.5
-
45
-
-
0036720290
-
The antifungal echinocandin caspofungin acetate kills growing cells of Aspergillus fumigatus in vitro
-
BOWMAN JC, HICKS PS, KURTZ MB et al.: The antifungal echinocandin caspofungin acetate kills growing cells of Aspergillus fumigatus in vitro. Antimicrob. Agents Chemother. (2002) 46:3001-3012.
-
(2002)
Antimicrob. Agents Chemother
, vol.46
, pp. 3001-3012
-
-
BOWMAN, J.C.1
HICKS, P.S.2
KURTZ, M.B.3
-
46
-
-
0036135430
-
Antifungal efficacy of caspofungin (MK-0991) in experimental pulmonary aspergillosis in persistently neutropenic rabbits: Pharmacokinetics, drug disposition, and relationship to galactomannan antigenemia
-
PETRAITIENE R, PETRAITIS V, GROLL AH et al.: Antifungal efficacy of caspofungin (MK-0991) in experimental pulmonary aspergillosis in persistently neutropenic rabbits: pharmacokinetics, drug disposition, and relationship to galactomannan antigenemia. Antimicrob. Agents Chemother. (2002) 46:12-23.
-
(2002)
Antimicrob. Agents Chemother
, vol.46
, pp. 12-23
-
-
PETRAITIENE, R.1
PETRAITIS, V.2
GROLL, A.H.3
-
47
-
-
0033836270
-
Efficacy of the echinocandin caspofungin against disseminated aspergillosis and candidiasis in cyclophosphamide-induced immunosuppressed mice
-
ABRUZZO GK, GILL CJ, FLATTERY AM et al.: Efficacy of the echinocandin caspofungin against disseminated aspergillosis and candidiasis in cyclophosphamide-induced immunosuppressed mice. Antimicrob. Agents Chemother. (2000) 44:2310-2318.
-
(2000)
Antimicrob. Agents Chemother
, vol.44
, pp. 2310-2318
-
-
ABRUZZO, G.K.1
GILL, C.J.2
FLATTERY, A.M.3
-
48
-
-
0035188628
-
Quantitative PCR assay to measure Aspergillus fumigatus burden in a murine model of disseminated aspergillosis: Demonstration of efficacy of caspofungin acetate
-
BOWMAN JC, ABRUZZO GK, ANDERSON JW et al.: Quantitative PCR assay to measure Aspergillus fumigatus burden in a murine model of disseminated aspergillosis: demonstration of efficacy of caspofungin acetate. Antimicrob. Agents Chemother. (2001) 45:3474-3481.
-
(2001)
Antimicrob. Agents Chemother
, vol.45
, pp. 3474-3481
-
-
BOWMAN, J.C.1
ABRUZZO, G.K.2
ANDERSON, J.W.3
-
49
-
-
24044479088
-
Efficacy of Abelcet and caspofungin, alone or in combination, against CNS aspergillosis in a murine model
-
IMAI J, SINGH G, FERNANDEZ B, CLEMONS KV, STEVENS DA: Efficacy of Abelcet and caspofungin, alone or in combination, against CNS aspergillosis in a murine model. J. Antimicrob. Chemother. (2005) 56:166-171.
-
(2005)
J. Antimicrob. Chemother
, vol.56
, pp. 166-171
-
-
IMAI, J.1
SINGH, G.2
FERNANDEZ, B.3
CLEMONS, K.V.4
STEVENS, D.A.5
-
50
-
-
16244373678
-
Efficacy of caspofungin against central nervous system Aspergillus fumigatus infection in mice determined by TaqMan PCR and CFU methods
-
SINGH G, IMAI J, CLEMONS KV, STEVENS DA: Efficacy of caspofungin against central nervous system Aspergillus fumigatus infection in mice determined by TaqMan PCR and CFU methods. Antimicrob. Agents Chemother. (2005) 49:1369-1376.
-
(2005)
Antimicrob. Agents Chemother
, vol.49
, pp. 1369-1376
-
-
SINGH, G.1
IMAI, J.2
CLEMONS, K.V.3
STEVENS, D.A.4
-
51
-
-
28844507822
-
Comparative efficacies of conventional amphotericin b, liposomal amphotericin B (AmBisome), caspofungin, micafungin, and voriconazole alone and in combination against experimental murine central nervous system aspergillosis
-
CLEMONS KV, ESPIRITU M, PARMAR R, STEVENS DA: Comparative efficacies of conventional amphotericin b, liposomal amphotericin B (AmBisome), caspofungin, micafungin, and voriconazole alone and in combination against experimental murine central nervous system aspergillosis. Antimicrob. Agents Chemother. (2005) 49:4867-4875.
-
(2005)
Antimicrob. Agents Chemother
, vol.49
, pp. 4867-4875
-
-
CLEMONS, K.V.1
ESPIRITU, M.2
PARMAR, R.3
STEVENS, D.A.4
-
52
-
-
4344587092
-
Paradoxical effect of caspofungin: Reduced activity against Candida albicans at high drug concentrations
-
STEVENS DA, ESPIRITU M, PARMAR R: Paradoxical effect of caspofungin: reduced activity against Candida albicans at high drug concentrations. Antimicrob. Agents Chemother. (2004) 48:3407-3411.
-
(2004)
Antimicrob. Agents Chemother
, vol.48
, pp. 3407-3411
-
-
STEVENS, D.A.1
ESPIRITU, M.2
PARMAR, R.3
-
55
-
-
28844490053
-
Attenuation of the activity of caspofungin at high concentrations against candida albicans: Possible role of cell wall integrity and calcineurin pathways
-
WIEDERHOLD NP, KONTOYIANNIS DP, PRINCE RA, LEWIS RE: Attenuation of the activity of caspofungin at high concentrations against candida albicans: possible role of cell wall integrity and calcineurin pathways. Antimicrob. Agents Chemother. (2005) 49:5146-5148.
-
(2005)
Antimicrob. Agents Chemother
, vol.49
, pp. 5146-5148
-
-
WIEDERHOLD, N.P.1
KONTOYIANNIS, D.P.2
PRINCE, R.A.3
LEWIS, R.E.4
-
56
-
-
0036840519
-
In vitro activity of caspofungin against Candida albicans biofilms
-
BACHMANN SP, VANDEWALLE K, RAMAGE G et al.: In vitro activity of caspofungin against Candida albicans biofilms. Antimicrob. Agents Chemother. (2002) 46:3591-3596.
-
(2002)
Antimicrob. Agents Chemother
, vol.46
, pp. 3591-3596
-
-
BACHMANN, S.P.1
VANDEWALLE, K.2
RAMAGE, G.3
-
57
-
-
33748035709
-
Evaluation of caspofungin and amphotericin B deoxycholate against Candida albicans biofilms in an experimental intravascular catheter infection model
-
SHUFORD JA, ROUSE MS, PIPER KE, STECKELBERG JM, PATEL R: Evaluation of caspofungin and amphotericin B deoxycholate against Candida albicans biofilms in an experimental intravascular catheter infection model. J. Infect. Dis. (2006) 194:710-713.
-
(2006)
J. Infect. Dis
, vol.194
, pp. 710-713
-
-
SHUFORD, J.A.1
ROUSE, M.S.2
PIPER, K.E.3
STECKELBERG, J.M.4
PATEL, R.5
-
58
-
-
0036841154
-
In vitro pharmacodynamic properties of three antifungal agents against preformed Candida albicans biofilms determined by time-kill studies
-
RAMAGE G, VANDEWALLE K, BACHMANN SP, WICKES BL, LOPEZ-RIBOT JL: In vitro pharmacodynamic properties of three antifungal agents against preformed Candida albicans biofilms determined by time-kill studies. Antimicrob. Agents Chemother. (2002) 46:3634-3636.
-
(2002)
Antimicrob. Agents Chemother
, vol.46
, pp. 3634-3636
-
-
RAMAGE, G.1
VANDEWALLE, K.2
BACHMANN, S.P.3
WICKES, B.L.4
LOPEZ-RIBOT, J.L.5
-
59
-
-
0034102140
-
Postantifungal effects of echinocandin, azole, and polyene antifungal agents against Candida albicans and Cryptococcus neoformans
-
ERNST EJ, KLEPSER ME, PFALLER MA: Postantifungal effects of echinocandin, azole, and polyene antifungal agents against Candida albicans and Cryptococcus neoformans. Antimicrob. Agents Chemother. (2000) 44:1108-1111.
-
(2000)
Antimicrob. Agents Chemother
, vol.44
, pp. 1108-1111
-
-
ERNST, E.J.1
KLEPSER, M.E.2
PFALLER, M.A.3
-
60
-
-
0037629905
-
Combination therapy in treatment of experimental pulmonary aspergillosis: Synergistic interaction between an antifungal triazole and an echinocandin
-
PETRAITIS V, PETRAITIENE R, SARAFANDI AA et al.: Combination therapy in treatment of experimental pulmonary aspergillosis: synergistic interaction between an antifungal triazole and an echinocandin. J. Infect. Dis. (2003) 187:1834-1843.
-
(2003)
J. Infect. Dis
, vol.187
, pp. 1834-1843
-
-
PETRAITIS, V.1
PETRAITIENE, R.2
SARAFANDI, A.A.3
-
61
-
-
24144486212
-
Efficacy of caspofungin and voriconazole combinations in experimental aspergillosis
-
MACCALLUM DM, WHYTE JA, ODDS FC: Efficacy of caspofungin and voriconazole combinations in experimental aspergillosis. Antimicrob. Agents Chemother. (2005) 49:3697-3701.
-
(2005)
Antimicrob. Agents Chemother
, vol.49
, pp. 3697-3701
-
-
MACCALLUM, D.M.1
WHYTE, J.A.2
ODDS, F.C.3
-
62
-
-
0035991955
-
Efficacy of caspofungin alone and in combination with voriconazole in a Guinea pig model of invasive aspergillosis
-
KIRKPATRICK WR, PEREA S, COCO BJ, PATTERSON TF: Efficacy of caspofungin alone and in combination with voriconazole in a Guinea pig model of invasive aspergillosis. Antimicrob. Agents Chemother. (2002) 46:2564-2568.
-
(2002)
Antimicrob. Agents Chemother
, vol.46
, pp. 2564-2568
-
-
KIRKPATRICK, W.R.1
PEREA, S.2
COCO, B.J.3
PATTERSON, T.F.4
-
63
-
-
0033998663
-
Synergistic antifungal activities of bafilomycin A(1), fluconazole, and the pneumocandin MK-0991/caspofungin acetate (L-743,873) with calcineurin inhibitors FK-506 and L-685,818 against Cryptococcus neoformans
-
DEL POETA M, CRUZ MC, CARDENAS ME, PERFECT JR, HEITMAN J: Synergistic antifungal activities of bafilomycin A(1), fluconazole, and the pneumocandin MK-0991/caspofungin acetate (L-743,873) with calcineurin inhibitors FK-506 and L-685,818 against Cryptococcus neoformans. Antimicrob. Agents Chemother. (2000) 44:739-746.
-
(2000)
Antimicrob. Agents Chemother
, vol.44
, pp. 739-746
-
-
DEL POETA, M.1
CRUZ, M.C.2
CARDENAS, M.E.3
PERFECT, J.R.4
HEITMAN, J.5
-
64
-
-
2142656385
-
In vitro interactions between antifungals and immunosuppressants against Aspergillus fumigatus
-
STEINBACH WJ, SCHELL WA, BLANKENSHIP JR, ONYEWU C, HEITMAN J, PERFECT JR: In vitro interactions between antifungals and immunosuppressants against Aspergillus fumigatus. Antimicrob. Agents Chemother. (2004) 48:1664-1669.
-
(2004)
Antimicrob. Agents Chemother
, vol.48
, pp. 1664-1669
-
-
STEINBACH, W.J.1
SCHELL, W.A.2
BLANKENSHIP, J.R.3
ONYEWU, C.4
HEITMAN, J.5
PERFECT, J.R.6
-
65
-
-
4644346490
-
Caspofungin versus liposomal ansphotericin B for empirical antifungal therapy in patients with persistent fever and neutropenia
-
WALSH TJ, TEPPLER H, DONOWITZ GR et al.: Caspofungin versus liposomal ansphotericin B for empirical antifungal therapy in patients with persistent fever and neutropenia. N. Engl. J. Med. (2004) 351:1391-1402.
-
(2004)
N. Engl. J. Med
, vol.351
, pp. 1391-1402
-
-
WALSH, T.J.1
TEPPLER, H.2
DONOWITZ, G.R.3
-
66
-
-
0035503456
-
A randomized double-blind study of caspofungin versus amphotericin for the treatment of candidal esophagitis
-
VILLANUEVA A, ARATHOON EG, GOTUZZO E, BERMAN RS, DINUBILE MJ, SABLE CA: A randomized double-blind study of caspofungin versus amphotericin for the treatment of candidal esophagitis. Clin. Infect. Dis. (2001) 33:1529-1535.
-
(2001)
Clin. Infect. Dis
, vol.33
, pp. 1529-1535
-
-
VILLANUEVA, A.1
ARATHOON, E.G.2
GOTUZZO, E.3
BERMAN, R.S.4
DINUBILE, M.J.5
SABLE, C.A.6
-
67
-
-
0036148508
-
Randomized, double-blind, multicenter study of caspofungin versus amphotericin B for treatment of oropharyngeal and esophageal candidiases
-
ARATHOON EG, GOTUZZO E, NORIEGA LM, BERMAN RS, DINUBILE MJ, SABLE CA: Randomized, double-blind, multicenter study of caspofungin versus amphotericin B for treatment of oropharyngeal and esophageal candidiases. Antimicrob. Agents Chemother. (2002) 46:451-457.
-
(2002)
Antimicrob. Agents Chemother
, vol.46
, pp. 451-457
-
-
ARATHOON, E.G.1
GOTUZZO, E.2
NORIEGA, L.M.3
BERMAN, R.S.4
DINUBILE, M.J.5
SABLE, C.A.6
-
68
-
-
0036701952
-
A randomized double-blind study of caspofungin versus fluconazole for the treatment of esophageal candidiasis
-
VILLANUEVA A, GOTUZZO E, ARATHOON EG et al.: A randomized double-blind study of caspofungin versus fluconazole for the treatment of esophageal candidiasis. Am. J. Med. (2002) 113:294-299.
-
(2002)
Am. J. Med
, vol.113
, pp. 294-299
-
-
VILLANUEVA, A.1
GOTUZZO, E.2
ARATHOON, E.G.3
-
69
-
-
0036797389
-
Efficacy of caspofungin in the treatment of esophageal candidiasis resistant to fluconazole
-
KARTSONIS N, DINUBILE MJ, BARTIZAL K, HICKS PS, RYAN D, SABLE CA: Efficacy of caspofungin in the treatment of esophageal candidiasis resistant to fluconazole. J. Acquir. Immune Defic. Syndr. (2002) 31:183-187.
-
(2002)
J. Acquir. Immune Defic. Syndr
, vol.31
, pp. 183-187
-
-
KARTSONIS, N.1
DINUBILE, M.J.2
BARTIZAL, K.3
HICKS, P.S.4
RYAN, D.5
SABLE, C.A.6
-
70
-
-
0037137576
-
Comparison of caspofungin and amphotericin B for invasive candidiasis
-
MORA-DUARTE J, BETTS R, ROTSTEIN C et al.: Comparison of caspofungin and amphotericin B for invasive candidiasis. N. Engl. J. Med. (2002) 347:2020-2029.
-
(2002)
N. Engl. J. Med
, vol.347
, pp. 2020-2029
-
-
MORA-DUARTE, J.1
BETTS, R.2
ROTSTEIN, C.3
-
71
-
-
14344249357
-
Native valve endocarditis due to Candida glabrata treated without valvular replacement: A potential role for caspofungin in the induction and maintenance treatment
-
JIMENEZ-EXPOSITO MJ, TORRES G, BARALDES A et al.: Native valve endocarditis due to Candida glabrata treated without valvular replacement: a potential role for caspofungin in the induction and maintenance treatment. Clin. Infect. Dis. (2004) 39:e70-e73.
-
(2004)
Clin. Infect. Dis
, vol.39
-
-
JIMENEZ-EXPOSITO, M.J.1
TORRES, G.2
BARALDES, A.3
-
73
-
-
32144462483
-
Candida prosthetic valve endocarditis cured by caspofungin therapy without valve replacement
-
RAJENDRAM R, ALP NJ, MITCHELL AR, BOWLER IC, FORFAR JC: Candida prosthetic valve endocarditis cured by caspofungin therapy without valve replacement. Clin. Infect. Dis. (2005) 40:e72-e74.
-
(2005)
Clin. Infect. Dis
, vol.40
-
-
RAJENDRAM, R.1
ALP, N.J.2
MITCHELL, A.R.3
BOWLER, I.C.4
FORFAR, J.C.5
-
74
-
-
28644442734
-
Candida glabrata prosthetic valve endocarditis treated successfully with fluconazole plus caspofungin without surgery: A case report and literature review
-
LYE DC, HUGHES A. O'BRIEN D, ATHAN E: Candida glabrata prosthetic valve endocarditis treated successfully with fluconazole plus caspofungin without surgery: a case report and literature review. Eur. J. Clin. Microbiol. Infect. Dis. (2005) 24:753-755.
-
(2005)
Eur. J. Clin. Microbiol. Infect. Dis
, vol.24
, pp. 753-755
-
-
LYE, D.C.1
HUGHES, A.2
O'BRIEN, D.3
ATHAN, E.4
-
75
-
-
33845465220
-
Successful treatment of refractory chronic disseminated candidiasis after prolonged administration of caspofungin in a child with acute myeloid leukemia
-
Epub ahead of print
-
KONTNY U, WALSH TJ, ROSSLER J, UHL M, NIEMEYER CM: Successful treatment of refractory chronic disseminated candidiasis after prolonged administration of caspofungin in a child with acute myeloid leukemia. Pediatr. Blood Cancer (2006). Epub ahead of print.
-
(2006)
Pediatr. Blood Cancer
-
-
KONTNY, U.1
WALSH, T.J.2
ROSSLER, J.3
UHL, M.4
NIEMEYER, C.M.5
-
76
-
-
11844252656
-
Management of endogenous fungal endophthalmitis with voriconazole and caspofungin
-
BREIT SM, HARIPRASAD SM, MIELER WF, SHAH GK, MILLS MD, GRAND MG: Management of endogenous fungal endophthalmitis with voriconazole and caspofungin. Am. J. Ophthalmol. (2005) 139:135-140.
-
(2005)
Am. J. Ophthalmol
, vol.139
, pp. 135-140
-
-
BREIT, S.M.1
HARIPRASAD, S.M.2
MIELER, W.F.3
SHAH, G.K.4
MILLS, M.D.5
GRAND, M.G.6
-
77
-
-
33644892911
-
Candida glabrata endophthalmitis treated successfully with caspofungin
-
SARRIA JC, BRADLEY JC, HABASH R, MITCHELL KT, KIMBROUGH RC, VIDAL AM: Candida glabrata endophthalmitis treated successfully with caspofungin. Clin. Infect. Dis. (2005) 40:e46-e48.
-
(2005)
Clin. Infect. Dis
, vol.40
-
-
SARRIA, J.C.1
BRADLEY, J.C.2
HABASH, R.3
MITCHELL, K.T.4
KIMBROUGH, R.C.5
VIDAL, A.M.6
-
78
-
-
10844290643
-
Refractory candidal meningitis in an immunocompromised patient cured by caspofungin
-
LIU KH, WU CJ, CHOU CH et al.: Refractory candidal meningitis in an immunocompromised patient cured by caspofungin. J. Clin. Microbiol. (2004) 42:5950-5953.
-
(2004)
J. Clin. Microbiol
, vol.42
, pp. 5950-5953
-
-
LIU, K.H.1
WU, C.J.2
CHOU, C.H.3
-
79
-
-
27944435518
-
Subtherapeutic ocular penetration of caspofungin and associated treatment failure in Candida albicans endophthalmitis
-
GAUTHIER GM, NORK TM, PRINCE R, ANDES D: Subtherapeutic ocular penetration of caspofungin and associated treatment failure in Candida albicans endophthalmitis. Clin. Infect. Dis. (2005) 41:e27-e28.
-
(2005)
Clin. Infect. Dis
, vol.41
-
-
GAUTHIER, G.M.1
NORK, T.M.2
PRINCE, R.3
ANDES, D.4
-
80
-
-
28244488640
-
Emergence of disseminated candidiasis caused by Candida krusei during treatment with caspofungin: Case report and review of literature
-
PELLETIER R, ALARIE I, LAGACE R, WALSH TJ: Emergence of disseminated candidiasis caused by Candida krusei during treatment with caspofungin: case report and review of literature. Med. Mycol. (2005) 43:559-564.
-
(2005)
Med. Mycol
, vol.43
, pp. 559-564
-
-
PELLETIER, R.1
ALARIE, I.2
LAGACE, R.3
WALSH, T.J.4
-
81
-
-
9644284471
-
Efficacy and safety of caspofungin for treatment of invasive aspergillosis in patients refractory to or intolerant of conventional antifungal therapy
-
MAERTENS J, RAAD I, PETRIKKOS G et al.: Efficacy and safety of caspofungin for treatment of invasive aspergillosis in patients refractory to or intolerant of conventional antifungal therapy. Clin. Infect. Dis. (2004) 39:1563-1571.
-
(2004)
Clin. Infect. Dis
, vol.39
, pp. 1563-1571
-
-
MAERTENS, J.1
RAAD, I.2
PETRIKKOS, G.3
-
82
-
-
4544236836
-
Combination antifungal therapy for invasive aspergillosis
-
MARR KA, BOECKH M, CARTER RA, KIM HW, COREY L: Combination antifungal therapy for invasive aspergillosis. Clin. Infect. Dis. (2004) 39:797-802.
-
(2004)
Clin. Infect. Dis
, vol.39
, pp. 797-802
-
-
MARR, K.A.1
BOECKH, M.2
CARTER, R.A.3
KIM, H.W.4
COREY, L.5
-
83
-
-
32844474763
-
Combination of voriconazole and caspofungin as primary therapy for invasive aspergillosis in solid organ transplant recipients: A prospective, multicenter, observational study
-
SINGH N, LIMAYE AP, FORREST G et al.: Combination of voriconazole and caspofungin as primary therapy for invasive aspergillosis in solid organ transplant recipients: a prospective, multicenter, observational study. Transplantation (2006) 81:320-326.
-
(2006)
Transplantation
, vol.81
, pp. 320-326
-
-
SINGH, N.1
LIMAYE, A.P.2
FORREST, G.3
-
84
-
-
0141863188
-
Echinocandin antifungal drugs
-
DENNING DW: Echinocandin antifungal drugs. Lancet (2003) 362:1142-1151.
-
(2003)
Lancet
, vol.362
, pp. 1142-1151
-
-
DENNING, D.W.1
|