Refractory candidal meningitis in an immunocompromised patient cured by caspofungin

Journal of Clinical Microbiology

Volumn 42, Issue 12, 2004, Pages 5950-5953

  Liu, Kung Hung ^a   Wu, Chi Jung ^a   Chou, Chen Hsi ^b   Lee, Hsin Chun ^a,b   Lee, Nan Yao ^a   Hung, Shao Tsung ^a   Ko, Wen Chien ^a,b  

^a NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; ANTINEOPLASTIC AGENT; CASPOFUNGIN; FLUCONAZOLE;

ADULT; ARTICLE; CANCER CHEMOTHERAPY; CANDIDA ALBICANS; CEREBROSPINAL FLUID CULTURE; DISEASE COURSE; FEMALE; FEVER; FUNGUS ISOLATION; HEADACHE; HUMAN; IMMUNE DEFICIENCY; LEUKEMIA; LUMBAR PUNCTURE; LYMPHOBLASTOMA; MENINGITIS; MYELODYSPLASIA; PLEOCYTOSIS; PRIORITY JOURNAL; TREATMENT OUTCOME;

ANTIFUNGAL AGENTS; CANDIDA ALBICANS; CANDIDIASIS; FEMALE; HUMANS; IMMUNOCOMPROMISED HOST; MENINGITIS, FUNGAL; MIDDLE AGED; PEPTIDES, CYCLIC; TREATMENT OUTCOME;

CANDIDA; CANDIDA ALBICANS; FUNGI;

EID: 10844290643     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.42.12.5950-5953.2004     Document Type: Article

References (14)

1. Casado, J. L., C. Quereda, J. Oliva, E. Navas, A. Moreno, V. Pintado, J. Cobo, and I. Corral. 1997. Candidal meningitis in HIV-infected patients: analysis of 14 cases. Clin. Infect. Dis. 25:673-676.
2. Chen, T. L., C. A. Tasi, C. P. Fung, M. Y. Lin, K. W. Yu, and C. Y. Liu. 2002. Clinical significance of Candida species isolated from cerebrospinal fluid. J. Microbiol. Immunol. Infect. 35:249-254.
3. Colombo, A. L., and R. C. Rosas. 2003. Successful treatment of an Aspergillus brain abscess with caspofungin: case report of a diabetic patient intolerant of amphotericin B. Eur. J. Clin. Microbiol. Infect. Dis. 22:575-576.
4. Deresinski, S. C., and D. A. Stevens. 2003. Caspofungin. Clin. Infect. Dis. 36:1445-1457.
5. Geers, T. A., and S. M. Gordon. 1999. Clinical significance of Candida species isolated from cerebrospinal fluid following neurosurgery. Clin. Infect. Dis. 28:1139-1147.
6. Gottfredsson, M., and J. R. Perfect. 2000. Fungal meningitis. Semin. Neurol. 20:307-322.
7. Hossain, M. A., G. H. Reyes, L. A. Long, P. K. Mukherjee, and M. A. Ghannoum. 2003. Efficacy of caspofungin combined with amphotericin B against azole-resistant Candida albicans. J. Antimicrob. Chemother. 51:1427-1429.
8. Jafari, H. S., S. L. Savier, C. Severien, F. Parras, I. Friedland, S. Rinderknecht, S. Ehrett, K. D. Olsen, C. Abramowsky, and G. H. McCracken. 1994. Effects of antifungal therapy on inflammation, sterilization, and histology in experimental Candida albicans meningitis. Antimicrob. Agents Chemother. 38:83-89.
9. Nguyen, M. H., and V. L. Yu. 1995. Meningitis caused by Candida species: an emerging problem in neurosurgical patients. Clin. Infect. Dis. 21:323-327.
10. Pappas, P. G., J. H. Rex, J. D. Sobel, S. G. Filler, W. E. Dismukes, T. J. Walsh, and J. E. Edwards. 2004. Guidelines for treatment of candidiasis. Clin. Infect. Dis. 38:161-189.
11. Rabah, R., W. J. Kupsky, and J. E. Haas. 1998. Arteritis and fatal subarachnoid hemorrhage complicating occult Candida meningitis. Unusual presentation in pediatric acquired immunodeficiency syndrome. Arch. Pathol. Lab. Med. 122:1030-1033.
12. Ramage, G., K. VandeWalle, S. P. Bachmann, B. L. Wickes, and J. L. Lopez-Ribot. 2002. In vitro pharmacodynamic properties of three antifungal agents against preformed Candida albicans biofilms determined by time-kill studies. Antimicrob. Agents Chemother. 46:3634-3636.
13. Sanchez-Portocarrero, J., E. Perez-Cecilia, O. Corral, J. Romero-Vivas, and J. J. Picazo. 2000. The central nervous system and infection by Candida species. Diagn. Microbiol. Infect. Dis. 37:169-179.
14. Voice, R. A., S. F. Bradley, J. A. Sangeorzan, and C. A. Kauffman. 1994. Chronic candidal meningitis: an uncommon manifestation of candidiasis. Clin. Infect. Dis. 19:60-66.