메뉴 건너뛰기




Volumn 49, Issue 12, 2005, Pages 5146-5148

Attenuation of the activity of caspofungin at high concentrations against Candida albicans: Possible role of cell wall integrity and calcineurin pathways

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; CASPOFUNGIN; FUNGAL PROTEIN; PROTEIN MKC1; UNCLASSIFIED DRUG;

EID: 28844490053     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.49.12.5146-5148.2005     Document Type: Article
Times cited : (118)

References (24)
  • 1
    • 0042818290 scopus 로고    scopus 로고
    • Genome-wide expression profiling of the response to polyene, pyrimidine, azolc, and echinocandin antifungal agents in Saccharomyces cerevisiae
    • Agarwal, A. K., P. D. Rogers, S. R. Baerson, M. R. Jacob, K. S. Barker, J. D. Cleary, L. A. Walker, D. G. Nagle, and A. M. Clark. 2003. Genome-wide expression profiling of the response to polyene, pyrimidine, azolc, and echinocandin antifungal agents in Saccharomyces cerevisiae. J. Biol. Chem. 278:34998-35015.
    • (2003) J. Biol. Chem. , vol.278 , pp. 34998-35015
    • Agarwal, A.K.1    Rogers, P.D.2    Baerson, S.R.3    Jacob, M.R.4    Barker, K.S.5    Cleary, J.D.6    Walker, L.A.7    Nagle, D.G.8    Clark, A.M.9
  • 3
    • 0027192868 scopus 로고
    • Isogenic strain construction and gene mapping in Candida albicans
    • Fonzi, W. A., and M. Y. Irwin. 1993. Isogenic strain construction and gene mapping in Candida albicans. Genetics 134:717-728.
    • (1993) Genetics , vol.134 , pp. 717-728
    • Fonzi, W.A.1    Irwin, M.Y.2
  • 4
    • 0032602932 scopus 로고    scopus 로고
    • Calcineurin. Structure, function, and inhibition
    • Hemenway, C. S., and J. Heitman. 1999. Calcineurin. Structure, function, and inhibition. Cell Biochem. Biophys. 30:115-151.
    • (1999) Cell Biochem. Biophys. , vol.30 , pp. 115-151
    • Hemenway, C.S.1    Heitman, J.2
  • 5
    • 12944300987 scopus 로고    scopus 로고
    • Caspofungin inhibits Rhizopus oryzae 1,3-β-D-glucan synthase, lowers burden in brain measured by quantitative PCR, and improves survival at a low but not a high dose during murine disseminated zygomycosis
    • Ibrahim, A. S., J. C. Bowman, V. Avanessian, K. Brown, B. Spellberg, J. E. Edwards, Jr., and C. M. Douglas. 2005. Caspofungin inhibits Rhizopus oryzae 1,3-β-D-glucan synthase, lowers burden in brain measured by quantitative PCR, and improves survival at a low but not a high dose during murine disseminated zygomycosis. Antimicrob. Agents Chemother. 49:721-727.
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 721-727
    • Ibrahim, A.S.1    Bowman, J.C.2    Avanessian, V.3    Brown, K.4    Spellberg, B.5    Edwards Jr., J.E.6    Douglas, C.M.7
  • 6
    • 0037326390 scopus 로고    scopus 로고
    • Combination of caspofungin with inhibitors of the Calcineurin pathway attenuates growth in vitro in Aspergillus species
    • Kontoyiannis, D. P., R. E. Lewis, N. Osherov, N. D. Albert, and G. S. May. 2003. Combination of caspofungin with inhibitors of the Calcineurin pathway attenuates growth in vitro in Aspergillus species. J. Antimicrob. Chemother. 51:313-316.
    • (2003) J. Antimicrob. Chemother. , vol.51 , pp. 313-316
    • Kontoyiannis, D.P.1    Lewis, R.E.2    Osherov, N.3    Albert, N.D.4    May, G.S.5
  • 7
    • 0030943354 scopus 로고    scopus 로고
    • Lipopeptide inhibitors of fungal glucan synthase
    • Kurtz, M. B., and C. M. Douglas. 1997. Lipopeptide inhibitors of fungal glucan synthase. J. Med. Vet. Mycol. 35:79-86.
    • (1997) J. Med. Vet. Mycol. , vol.35 , pp. 79-86
    • Kurtz, M.B.1    Douglas, C.M.2
  • 8
    • 18844393429 scopus 로고    scopus 로고
    • Genome-wide expression profiling of the response to azole, polyene, echinocandin, and pyrimidine antifungal agents in Candida albicans
    • Liu, T. T., R. E. Lee, K. S. Barker, L. Wei, R. Homayouni, and P. D. Rogers. 2005. Genome-wide expression profiling of the response to azole, polyene, echinocandin, and pyrimidine antifungal agents in Candida albicans. Antimicrob. Agents Chemother. 49:2226-2236.
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 2226-2236
    • Liu, T.T.1    Lee, R.E.2    Barker, K.S.3    Wei, L.4    Homayouni, R.5    Rogers, P.D.6
  • 9
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2 - ΔΔCT method
    • Livak, K. J., and T. D. Schmittgen. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2 - ΔΔCT method. Methods 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 10
    • 4644302726 scopus 로고    scopus 로고
    • Genomic approach to identification of mutations affecting caspofungin susceptibility in Saccharomyces cerevisiae
    • Markovich, S., A. Yekutiel, I. Shalit, Y. Shadkchan, and N. Osherov. 2004. Genomic approach to identification of mutations affecting caspofungin susceptibility in Saccharomyces cerevisiae. Antimicrob. Agents Chemother. 48:3871-3876.
    • (2004) Antimicrob. Agents Chemother. , vol.48 , pp. 3871-3876
    • Markovich, S.1    Yekutiel, A.2    Shalit, I.3    Shadkchan, Y.4    Osherov, N.5
  • 13
    • 0029938309 scopus 로고    scopus 로고
    • Genetic evidence for the functional redundancy of the calcineurin- and Mpk1-mediated pathways in the regulation of cellular events important for growth in Saccharomyces cerevisiae
    • Nakamura, T., T. Ohmoto, D. Hirata, E. Tsuchiya, and T. Miyakawa. 1996. Genetic evidence for the functional redundancy of the calcineurin- and Mpk1-mediated pathways in the regulation of cellular events important for growth in Saccharomyces cerevisiae. Mol. Gen. Genet. 251:211-219.
    • (1996) Mol. Gen. Genet. , vol.251 , pp. 211-219
    • Nakamura, T.1    Ohmoto, T.2    Hirata, D.3    Tsuchiya, E.4    Miyakawa, T.5
  • 14
    • 0031888386 scopus 로고    scopus 로고
    • A role for the MAP kinase gene MKC1 in cell wall construction and morphological transitions in Candida albicans
    • Navarro-Garcia, F., R. Alonso-Monge, H. Rico, J. Pla, R. Sentandreu, and C. Nombela. 1998. A role for the MAP kinase gene MKC1 in cell wall construction and morphological transitions in Candida albicans. Microbiology 144:411-424.
    • (1998) Microbiology , vol.144 , pp. 411-424
    • Navarro-Garcia, F.1    Alonso-Monge, R.2    Rico, H.3    Pla, J.4    Sentandreu, R.5    Nombela, C.6
  • 15
    • 0028900072 scopus 로고
    • Functional characterization of the MKC1 gene of Candida albicans, which encodes a mitogen-activated protein kinase homolog related to cell integrity
    • Navarro-García, F., M. Sánchez, J. Pla, and C. Nombela. 1995. Functional characterization of the MKC1 gene of Candida albicans, which encodes a mitogen-activated protein kinase homolog related to cell integrity. Mol. Cell. Biol. 15:2197-2206.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2197-2206
    • Navarro-García, F.1    Sánchez, M.2    Pla, J.3    Nombela, C.4
  • 16
    • 0035991843 scopus 로고    scopus 로고
    • Overexpression of Sbe2p, a Golgi protein, results in resistance to caspofungin in Saccharomyces cerevisiae
    • Osherov, N., G. S. May, N. D. Albert, and D. P. Kontoyiannis. 2002. Overexpression of Sbe2p, a Golgi protein, results in resistance to caspofungin in Saccharomyces cerevisiae. Antimicrob. Agents Chemother. 46:2462-2469.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 2462-2469
    • Osherov, N.1    May, G.S.2    Albert, N.D.3    Kontoyiannis, D.P.4
  • 17
    • 0036841154 scopus 로고    scopus 로고
    • In vitro pharmacodynamic properties of three antifungal agents against preformed Candida albicans biofilms determined by time-kill studies
    • Ramage, G., K. VandeWalle, S. P. Bachmann, B. L. Wickes, and J. L. Lopez-Ribot. 2002. In vitro pharmacodynamic properties of three antifungal agents against preformed Candida albicans biofilms determined by time-kill studies. Antimicrob. Agents Chemother. 46:3634-3636.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 3634-3636
    • Ramage, G.1    Vandewalle, K.2    Bachmann, S.P.3    Wickes, B.L.4    Lopez-Ribot, J.L.5
  • 18
    • 0346433839 scopus 로고    scopus 로고
    • The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signaling
    • Reinoso-Martin, C., C. Schuller, M. Schuetzer-Muehlbauer, and K. Kuchler. 2003. The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signaling. Eukaryot. Cell 2:1200-1210.
    • (2003) Eukaryot. Cell , vol.2 , pp. 1200-1210
    • Reinoso-Martin, C.1    Schuller, C.2    Schuetzer-Muehlbauer, M.3    Kuchler, K.4
  • 19
    • 0038016755 scopus 로고    scopus 로고
    • Calcineurin a of Candida albicans: Involvement in antifungal tolerance, cell morphogenesis and virulence
    • Sanglard, D., F. Ischer, O. Marchetti, J. Entenza, and J. Bille. 2003. Calcineurin A of Candida albicans: involvement in antifungal tolerance, cell morphogenesis and virulence. Mol. Microbiol. 48:959-976.
    • (2003) Mol. Microbiol. , vol.48 , pp. 959-976
    • Sanglard, D.1    Ischer, F.2    Marchetti, O.3    Entenza, J.4    Bille, J.5
  • 20
    • 0035048028 scopus 로고    scopus 로고
    • Differential regulation of cell wall biogenesis during growth and development in yeast
    • Smits, G. J., H. van den Ende, and F. M. Klis. 2001. Differential regulation of cell wall biogenesis during growth and development in yeast. Microbiology 147:781-794.
    • (2001) Microbiology , vol.147 , pp. 781-794
    • Smits, G.J.1    Van Den Ende, H.2    Klis, F.M.3
  • 21
    • 4344587092 scopus 로고    scopus 로고
    • Paradoxical effect of caspofungin: Reduced activity against Candida albicans at high drug concentrations
    • Stevens, D. A., M. Espiritu, and R. Parmar. 2004. Paradoxical effect of caspofungin: reduced activity against Candida albicans at high drug concentrations. Antimicrob. Agents Chemother. 48:3407-3411.
    • (2004) Antimicrob. Agents Chemother. , vol.48 , pp. 3407-3411
    • Stevens, D.A.1    Espiritu, M.2    Parmar, R.3
  • 23
    • 4944230721 scopus 로고    scopus 로고
    • Pharmacodynamics of caspofungin in a murine model of invasive pulmonary aspergillosis: Evidence of concentration-dependent activity
    • Wiederhold, N. P., D. P. Kontoyiannis, J. Chi, R. A. Prince, V. H. Tam, and R. E. Lewis. 2004. Pharmacodynamics of caspofungin in a murine model of invasive pulmonary aspergillosis: evidence of concentration-dependent activity. J. Infect. Dis. 190:1464-1471.
    • (2004) J. Infect. Dis. , vol.190 , pp. 1464-1471
    • Wiederhold, N.P.1    Kontoyiannis, D.P.2    Chi, J.3    Prince, R.A.4    Tam, V.H.5    Lewis, R.E.6
  • 24
    • 2642616985 scopus 로고    scopus 로고
    • Temperature-induced expression of yeast FKS2 is under the dual control of protein kinase C and calcineurin
    • Zhao, C., U. S. Jung, P. Garrett-Engele, T. Roe, M. S. Cyert, and D. E. Levin. 1998. Temperature-induced expression of yeast FKS2 is under the dual control of protein kinase C and calcineurin. Mol. Cell. Biol. 18:1013-1022.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 1013-1022
    • Zhao, C.1    Jung, U.S.2    Garrett-Engele, P.3    Roe, T.4    Cyert, M.S.5    Levin, D.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.